Mereo BioPharma Group plc AIM Rule 17 Disclosure Statement (7301K)

TIDMMPH

RNS Number : 7301K

Mereo BioPharma Group plc

17 December 2018

Mereo BioPharma Group plc

("Mereo" or the "Company")

AIM Rule 17 Disclosure Statement

London, 17 December 2018 - Mereo BioPharma Group plc (AIM: MPH), a clinical stage UK based biopharmaceutical company focused on rare diseases, announces in accordance with AIM Rule 17 that Richard Jones, Chief Financial Officer of Mereo, has been appointed as a Non-Executive Director of Alliance Pharma plc with effect from 1 January 2019.

Enquiries:

 
Mereo BioPharma Group plc                    [phone] 
Denise Scots-Knight, Chief Executive 
 Officer 
Richard Jones, Chief Financial Officer 
 
Cantor Fitzgerald Europe (Nominated 
 Adviser and Broker)                         [phone] 
Phil Davies 
Will Goode 
Rick Thompson 
 
RBC Capital Markets (Joint Broker)           [phone] 
Rupert Walford 
Jamil Miah 
 
FTI Consulting (Public Relations Adviser)    [phone] 
Simon Conway 
Brett Pollard 
 
Burns McClellan (US Public Relations 
 Advisor to Mereo Biopharma)                +01 (0) 212 213 0006 
Lisa Burns 
Ami Bavishi 
 

About Mereo

Mereo is a biopharmaceutical company focused on the development and commercialization of innovative therapeutics that aim to improve outcomes for patients with rare diseases. Mereo's strategy is to selectively acquire product candidates that have already received significant investment from pharmaceutical companies and that have substantial preclinical, clinical and manufacturing data packages. In December 2018, Mereo announced the proposed combination of Mereo and OncoMed Pharmaceuticals, with the transaction expected to close in the first half of 2019. Each of Mereo's four product candidates has previously generated positive clinical data for Mereo's target indication or in a related indication. Since inception Mereo has commenced large, randomized, placebo-controlled Phase 2 clinical trials for all four of the product candidates:

-- BPS-804 for osteogenesis imperfecta (OI). The Company recently announced completion of enrolment with 112 adult patients in a Phase 2b dose ranging study with some initial data expected in the H1 2019 and top-line dose ranging data in late 2019. A pediatric Phase 3 study design has also been approved by the EMA. BPS-804 has orphan designation in the US and EU and has been accepted into the PRIME and Adaptive Pathways in EU;

-- MPH-966 for alpha-1 antitrypsin deficiency (AATD). The Company recently announced first patient in in a Phase 2 dose ranging study in the US with data expected in late 2019;

-- BCT-197 for acute exacerbations of COPD (AECOPD). The Company announced positive top-line Phase 2 data in December 2017; and

-- BGS-649 for hypogonadotropic hypogonadism (HH). The Company announced positive top-line Phase 2b data in March 2018.

-- As at September 30, 2018 Mereo had (unaudited) total cash resources of approximately US$44.6 million

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December 17, 2018 10:44 ET (15:44 GMT)