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Share Name | Share Symbol | Market | Type | Share ISIN | Share Description |
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Lipoxen | LSE:LPX | London | Ordinary Share | GB00B08NWV55 | ORD 0.5P |
Price Change | % Change | Share Price | Bid Price | Offer Price | High Price | Low Price | Open Price | Shares Traded | Last Trade | |
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0.00 | 0.00% | 7.875 | 0.00 | 01:00:00 |
Industry Sector | Turnover | Profit | EPS - Basic | PE Ratio | Market Cap |
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0 | 0 | N/A | 0 |
RNS Number:1634Q Lipoxen PLC 17 March 2008 Lipoxen reports further advancement of its DNA vaccine delivery patent portfolio US allows further patent for Lipoxen's ImuXen(R) technology London, UK, 17th March 2008 - Lipoxen PLC, (AIM:LPX) a bio-pharmaceutical company specialising in the development of high value differentiated biologicals, vaccines and oncology drugs, announces today that an important ImuXen(R) patent (No 10/149670) has been allowed in the US, following grant in Europe in 2004. This extension of Lipoxen's DNA vaccine delivery patent estate covers its capisome technology, which relates to the entrapment of DNA vaccines into liposomes made of uncharged lipids rather than cationic (positively charged) liposomes. In the capisome approach, DNA is complexed with calcium and then trapped into neutral liposomes. Recognising the need for a new delivery system as, although harmless if used over a few injections, cationic lipids can present problems on prolonged use, Lipoxen developed a technology that could be applied chronically, and is viewed as essential for a more widespread use for DNA therapy. A further advantage of the capisome approach is that the delivery method is not limited to DNA vaccines, and it has the potential to be used in gene therapy and other nucleic acid-based therapies such as siRNA. Other benefits are expected to include low toxicity and capability to carry large amounts of DNA. The technology can also be applied in conjunction with Lipoxen's current ImuXen co-delivery approach, in which DNA vaccines and the proteins they encode are delivered together in order to provide an enhanced immune response. The allowance of this patent comes shortly after one of Lipoxen's cornerstone ImuXen patents (No 10/617734), which covers the encapsulation of DNA inside a liposome, was allowed in the US. Both these approaches further protect Lipoxen's position in the field of DNA vaccine delivery technology and help ensure that its advanced ImuXen technology continues to be at the forefront of novel vaccine development. M. Scott Maguire, CEO of Lipoxen, said: "Realising that a strong intellectual property position is key to our future success, the allowance of this patent in the US further strengthens our position as a leader in the development of DNA delivery technology with ImuXen. The potential widespread use of the capisome technology beyond vaccines into delivery of other DNA-based medicines increases the value of our patent estate, and we expect it to play a key role in the generation of further deals and R&D collaborations." Ends Enquiries Lipoxen PLC M. Scott Maguire, Chief Executive Officer +44 (0)20 7691 3583 Landsbanki Securities (UK) Limited (nominated adviser) Shaun Dobson / Claes Spang +44 (0)20 7426 9000 Citigate Dewe Rogerson +44 (0)20 7638 9571 David Dible / Emma Palmer Notes to Editors Lipoxen PLC (AIM:LPX) is a biopharmaceutical company specializing in the development of high value differentiated biologicals, vaccines and oncology drugs. Products currently under development include improved formulations of important biologicals such as erythropoietin (EPO), G-CSF, insulin and Interferon-alpha. Lipoxen has two products in clinical development SuliXen, a long acting insulin and long-acting EPO. These novel products, which are based on Lipoxen's proprietary PolyXen(R) technology, each address markets in excess of US$1 billion. Lipoxen's technology is designed to improve the stability, biological half-life and immunologic characteristics of therapeutic proteins naturally. Lipoxen has two further naturally-derived proprietary delivery technologies, ImuXen(R) and a related liposomal technology for the formulation of cytotoxic oncology drugs, which are being developed to enhance the efficacy and safety of various vaccines such as a multivalent Hepatitis B-E and pneumococcal vaccines, as well as a number of anti-cancer agents like paclitaxel. The Company's proprietary delivery technologies are attracting significant interest and Lipoxen is currently co-developing products with the Serum Institute of India Limited (one of the world's leading vaccine companies, India's largest biotech company and a major shareholder in Lipoxen) and has license agreements in place with Baxter International and InterVet, a leading animal health company. Lipoxen was admitted to trading on the AIM Market of the London Stock Exchange in January 2006. This announcement includes 'forward-looking statements' which include all statements other than statements of historical facts, including, without limitation, those regarding the Company's financial position, business strategy, plans and objectives of management for future operations (including development plans and objectives relating to the Company's products and services), and any statements preceded by, followed by or that include forward-looking terminology such as the words 'targets', 'believes', 'estimates', 'expects', 'aims', 'intends', 'will', 'can', 'may', 'anticipates', 'would', 'should', 'could' or similar expressions or the negative thereof. Such forward-looking statements involve known and unknown risks, uncertainties and other important factors beyond the Company's control that could cause the actual results, performance or achievements of the Company to be materially different from future results, performance or achievements expressed or implied by such forward-looking statements. Such forward-looking statements are based on numerous assumptions regarding the Company's present and future business strategies and the environment in which the Company will operate in the future. Among the important factors that could cause the Company's actual results, performance or achievements to differ materially from those in forward-looking statements include those relating to The Company's funding requirements, regulatory approvals, clinical trials, reliance on third parties, intellectual property, key personnel and other factors. These forward-looking statements speak only as at the date of this announcement. The Company expressly disclaims any obligation or undertaking to disseminate any updates or revisions to any forward-looking statements contained in this announcement to reflect any change in the Company's expectations with regard thereto or any change in events, conditions or circumstances on which any such statements are based. As a result of these factors, readers are cautioned not to rely on any forward-looking statement. This information is provided by RNS The company news service from the London Stock Exchange END MSCSFAFLLSASEDD
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