SAR - BioFocus PLC-Replacemnt

RNS Number:9923R
ISIS Asset Management PLC
12 November 2003




The 'SAR - Protec PLC' announcement released on 4 November 2003 at 11.35 under
RNS No 6444R has been amended.

Amendments are identified with an asterisk (*).

The full amended text is shown below.



                                                        FORM SAR 3


                                       Date of disclosure 4TH NOVEMBER 03

                 DISCLOSURE UNDER RULE 3 OF THE RULES GOVERNING
                   SUBSTANTIAL ACQUISITIONS OF SHARES ("SARs")

                 
Date of acquisition     3RD NOVEMBER 2003

Acquisition in *BIOFOCUS PLC* (name of company)


(1) Class of voting shares    Number of shares/rights   If rights over shares
    (eg ordinary shares)      over shares acquired      acquired, as opposed
                                                        to the shares
                                                        themselves, specify
                                                        nature of rights

    ...ORDINARY SHARES.....   ..75,000....shares    .....................
                              ...N/A..........rights


(2) Resultant total holding   Resultant total holding   Total percentage
    of voting shares (and %   of rights over shares
    of total voting shares    (and % of total voting
    in issue)                 shares in issue)

    2,456,802                  ...............(    %)        15.42


(3) Party making disclosure     ISIS ASSET MANAGEMENT

(4)  (a)  Name of person acquiring shares or rights over shares
          and, if different, beneficial owner           ISIS ASSET MANAGEMENT

     (b)  Names of any other persons acting by
          agreement or understanding (see SAR 5)............................


Signed, for and on behalf of the party named in (3) above...................

(Also print name of signatory).....DOUGLAS STEWART...............

Telephone and extension number.....0131 465 1052...............

Note. Under SAR 5, the holdings of and acquisitions by persons acting by
agreement or understanding must be aggregated and treated as a holding of or
acquisition by one person.  Note 3 on SAR 5 requires persons who must aggregate
holdings to disclose certain disposals.

For full details of the SARs disclosure requirements, see Rules 3 and 5 of the
SARs.  If in doubt, contact the Panel on Takeovers and Mergers, Monitoring 
Section, Tel. No: 020 7638 0129.


                      This information is provided by RNS
            The company news service from the London Stock Exchange

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