ADVFN Logo ADVFN

We could not find any results for:
Make sure your spelling is correct or try broadening your search.

Trending Now

Toplists

It looks like you aren't logged in.
Click the button below to log in and view your recent history.

Hot Features

Registration Strip Icon for charts Register for streaming realtime charts, analysis tools, and prices.

CYX Cytomyx Hldgs

1.10
0.00 (0.00%)
Last Updated: 01:00:00
Delayed by 15 minutes
Cytomyx Investors - CYX

Cytomyx Investors - CYX

Share Name Share Symbol Market Stock Type
Cytomyx Hldgs CYX London Ordinary Share
  Price Change Price Change % Share Price Last Trade
0.00 0.00% 1.10 01:00:00
Open Price Low Price High Price Close Price Previous Close
1.10
more quote information »

Top Investor Posts

Top Posts
Posted at 19/1/2005 10:53 by raldo
Cytomyx Holdings PLC
19 January 2005


For immediate release 19 January 2005

CYTOMYX HOLDINGS PLC

('Cytomyx' or 'the Company')

Preliminary results for the year ended 30 September 2004


Cytomyx Holdings plc (AIM: CYX), the leading provider of drug discovery products
and services, is pleased to announce its full year results for the year ended 30
September 2004.

Highlights:

• Turnover up 11 per cent at £5.66 million (2003: £5.10 million)
• Gross profit up 32 per cent at £3.38 million (2003: £2.56 million)
• Gross profit margin 60 per cent (2003: 50 per cent)
• Net loss £915,661 (2003: net loss £414,051), reflecting investment in new
US operations
• Successful institutional Placing to raise £1.9 million completed January
2004
• Acquisition of Clinomics Biosciences Inc., a US company with a major
collection of highly characterised human tissue samples, in January 2004
• Clinomics' new Oncology Cell Signalling Database licensed to AstraZeneca
in March 2004
• Significant expansion in the number of ion channel cell lines from 2 to 17
• Collaboration with Moffit Cancer Center, Florida, in July 2004



Highlights post the year end:

• Molecular Probes distribution contract reinstated
• Clinomics' integration with Cytomyx Ltd and equity fund raising facility
approved in December 2004
• $2.5 million convertible loan facility arranged through Laurus Master Fund
in December 2004



Commenting on the results, Mike Kerins, Cytomyx' Chief Executive, said: 'We are
delighted with the progress made during the year, reflected in the fact that we
now work regularly for eight out of the top ten pharmaceutical companies
worldwide. The developments post the year end, including additional flexibility
in financing the company, together with current trading give us confidence in
the year ahead.'



For further information, please contact:

Cytomyx Holdings plc 01223 508191
Mike Kerins, Chief Executive

Buchanan Communications 020 7466 5000
Mark Court/Mary-Jane Johnson

The Wall Street Group +1 212 888 4848
Ron Stabiner





CYTOMYX HOLDINGS PLC

Preliminary Statement for the year ended 30 September 2004

CHAIRMAN'S STATEMENT

Cytomyx has had an exciting year of growth and consolidation. This has included
not only a strengthening of gross profit margins through new high value
contracts in the second half of the financial year, but also the acquisition in
January 2004 of US-based Clinomics Biosciences Inc ('Clinomics'), a company
whose unique capabilities give us the potential for substantial growth in future
years.

As a result of this acquisition, we have been pleased to welcome Stephen Turner,
the Founder and CEO of Clinomics, to our Board. Mr Turner has a distinguished
track record in the life science industry and will be a major contributor to the
future direction of the group.

The acquisition of Clinomics will facilitate a number of plans that we have to
strengthen our offering of drug discovery technology solutions on a global
basis.

During the year, Cytomyx Ltd has greatly accelerated its progress in the
development of high value products used in drug discovery. A major effort to
develop recombinant cell lines that express ion channel proteins has been highly
successful and we are now recognised as the world's leading developer of these
systems. These high value products are used to develop new treatments in areas
such as pain, epilepsy and heart disease, as well as being widely used to test
new drugs for their potential to cause serious cardiac toxicity side effects.
These products have shown considerable promise for future revenues.

Clinomics has established a very large collection of human tissue samples,
spanning most of the major diseases currently being investigated by the
pharmaceutical industry. All of the samples in the collection are linked to
detailed clinical information from the donor patient and these are used by our
clients to discover new genes involved in disease progression.

Since January, we have relocated Clinomics to a new facility in Albany, New
York, and made rapid strides in expanding its offering of products to the
pharmaceutical industry. During the year we were successful in securing a number
of major contracts with leading pharmaceutical companies, including AstraZeneca.
In addition, we entered into a major new initiative to develop new Cancer Tissue
MicroArrays (our core technology) with the prestigious Moffitt Cancer Centre in
Florida.

We believe that there are many significant synergies between the Clinomics and
Cytomyx Ltd businesses and, in order to best exploit these, it is our intention
to merge the two companies into a single global business unit early in 2005.
While the integration of Clinomics is not yet complete, early indications are
that this will be a powerful and accretive acquisition of the Cytomyx group.

Cambridge BioScience Ltd continued to perform well, and, after extensive
negotiation, we were delighted to announce re-attaining the distribution
contract for Molecular Probes following its sale to Invitrogen Corporation.
Cambridge BioScience Ltd during the year has also initiated a number of exciting
new distribution contracts with innovative US suppliers.

Fund raising

Interest in the group's key strategic products and services has been strong
during the year. We also recognise the need to strengthen our position in the
critical US marketplace, which accounts for around 50% of global pharmaceutical
R&D expenditure. The acquisition of Clinomics was our first major step towards
strengthening our activities in the US.

As a result of this acquisition, we have received interest from several US-based
investors and in December we agreed to an offer of a $2.5m convertible loan
facility from Laurus Funds that will expand available working capital necessary
for our increased level of activity in the US. We anticipate continued growth
through the group in light of our new US activities.

Financial

The group grew its revenues by more than 11% to £5,664,252 in 2004 from
£5,101,315 in 2003. This growth came from new and acquired activities, some of
the growth being temporarily masked by the temporary loss of the Molecular
Probes contract and the decision to wind down some low margin activities such as
DNA sequencing services. Gross profit has grown to £3,383,859 from £2,560,138 in
2003. Notwithstanding the net loss in the first half which, to a large extent,
reflected costs related to the investment in and relocation of Clinomics, our
second half provided firm evidence of increasing gross profit margins including
the positive impact of the Clinomics' acquisition.



Dividend

In light of the loss for the year, the early stage nature of the company and the
ongoing need for investment to grow the Cytomyx Group, the Board does not
recommend the payment of a dividend for the year.

Summary

The group has continued to focus on developing world class technologies for use
in pharmaceutical R&D and we are now seeing strong demand for these key
products. The strategically important acquisition of Clinomics puts us in a
leading position in a major growth market and provides access to the critical US
market. We have also seen strong interest from the US investment community who
have taken notice of our increasing focus on business opportunities in North
America.

We believe 2005 will be a year of significant consolidation, growth and
development of our increasingly successful pharmaceutical solutions business.





Dr. Bill Mason

Chairman

19 January 2005





CONSOLIDATED PROFIT AND LOSS ACCOUNT

Year ended 30 September 2004
Note 2004 2003
£ £

TURNOVER
Existing operations 4,993,523 5,101,315
Acquisitions 670,729 -

Turnover - continuing operations 5,664,252 5,101,315

Cost of sales (2,280,393) (2,541,177)

Gross profit 3,383,859 2,560,138

Distribution costs (137,300) (152,937)
Administrative expenses (4,218,815) (2,757,265)
Other operating income - 15,969


OPERATING LOSS
Existing operations (814,880) (334,095)
Acquisitions (157,376) -

Operating loss - continuing operations (972,256) (334,095)
Restructuring costs - (118,086)

LOSS ON ORDINARY ACTIVITIES BEFORE INTEREST (972,256) (452,181)

Interest receivable and similar income 22,124 7,592
Interest payable and similar charges (46,960) (32,328)

LOSS ON ORDINARY ACTIVITIES BEFORE TAXATION (997,092) (476,917)
Tax on loss on ordinary activities 81,431 62,866

LOSS FOR THE FINANCIAL YEAR (915,661) (414,051)


Loss per ordinary share (pence) 2 (2.42) (1.59)

Diluted loss per ordinary share (pence) 2 (2.42) (1.59)






CONSOLIDATED BALANCE SHEET

30 September 2004
Note 2004 2003
£ £

FIXED ASSETS
Intangible assets 4,479,363 1,233,895
Tangible assets 1,615,138 1,069,576

6,094,501 2,303,471


CURRENT ASSETS
Stocks 477,815 375,799
Debtors
Due after more than one year 60,600 60,600
Due within one year 964,402 1,184,044
Short term investments 450,000 -
Cash at bank and in hand 387,553 414,529

2,340,370 2,034,972
CREDITORS: amounts falling due
within one year (1,330,278) (869,695)

NET CURRENT ASSETS 1,010,092 1,165,277

TOTAL ASSETS LESS CURRENT LIABILITIES 7,104,593 3,468,748

CREDITORS: amounts falling due
after more than one year (880,194) (1,158,327)

6,224,399 2,310,421


CAPITAL AND RESERVES 3
Called up share capital 1,044,809 701,230
Share premium account 5,107,518 3,478,203
Share capital to be issued 675,817 -
Merger reserve 2,089,460 (99,900)
Foreign exchange reserve (8,432) -
Profit and loss account (2,684,773) (1,769,112)

EQUITY SHAREHOLDERS' FUNDS 6,224,399 2,310,421




COMPANY BALANCE SHEET

30 September 2004
Note 2004 2003
£ £

FIXED ASSETS
Tangible assets 2,495 -
Investments 3,394,016 102,000

3,396,511 102,000


CURRENT ASSETS
Debtors
Due after more than one year 4,654,580 3,856,571
Due within one year 22,364 27,287
Short term investments 450,000 -
Cash at bank and in hand 74,967 6,180

5,201,911 3,890,038

CREDITORS: amounts falling due within one year (221,309) (42,500)

NET CURRENT ASSETS 4,980,602 3,847,538

TOTAL ASSETS LESS CURRENT LIABILITIES 8,377,113 3,949,538


CAPITAL AND RESERVES 3
Called up share capital 1,044,809 701,230
Share premium account 5,107,518 3,478,203
Share capital to be issued 675,817 -
Merger reserve 2,189,360 -
Profit and loss account (640,391) (229,895)

EQUITY SHAREHOLDERS' FUNDS 8,377,113 3,949,538




CONSOLIDATED CASH FLOW STATEMENT

Year ended 30 September 2004
Note 2004 2003
£ £

Net cash outflow from operating activities 4 (122,629) (920,219)

Returns on investments and servicing of finance 5 (24,836) (24,736)

Taxation 5 58,338 10,880

Capital expenditure and financial investment 5 (617,755) (74,002)

Acquisitions 5 (243,003) (369,982)

Net cash outflow before management of liquid resources and
financing (949,885) (1,378,059)

Management of liquid resources 5 (450,000) -

Financing 5 1,372,909 1,868,502

(Decrease) increase in cash in the year 6 (26,976) 490,443




RECONCILIATION OF NET CASH FLOW TO MOVEMENT IN NET DEBT

2004 2003
£ £

(Decrease) increase in cash in the year (26,976) 490,443
Cash outflow from decrease in lease financing 44,142 24,320
Cash outflow from decrease in loan notes 365,464 25,000
Cash inflow from new bank loan - (100,000)
Cash outflow from increase in liquid resources 450,000 -

Change in net debt resulting from cash flows 832,630 439,763
Loans and finance leases acquired with subsidiary (48,789) -
New finance leases (34,129) (46,243)
New loan notes - (1,180,000)

Change in net debt 749,712 (786,480)

Net debt at beginning of year (911,827) (125,347)

Net debt at end of year (162,115) (911,827)






STATEMENT OF TOTAL RECOGNISED GAINS AND LOSSES

Year ended 30 September 2004
2004 2003

£ £

Loss for the financial year (915,661) (414,051)
Currency translation difference on foreign currency net
investments (8,432) -

Total gains and losses since last annual report (924,093) (414,051)






NOTES

The information set out above does not constitute the Company's statutory
accounts for the years ended 30 September 2004 or 2003, but is derived from
those accounts, and is prepared on the basis of the accounting policies as
set out in the most recently published set of annual financial statements.
Statutory accounts for 2003 have been delivered to the Registrar of Companies,
and those for 2004 will be delivered following the Company's Annual General
Meeting. The auditors have reported on those accounts; their report was
unqualified and did not contain a statement under section 237(2) or (3) of the
Companies Act 1985.

LOSS PER ORDINARY SHARE

The diluted loss per share takes into account the dilutive effect of share
options. Ordinary shares which are potentially issuable are only included in the
calculation of diluted earnings per share if their issue would decrease net
profit per share or increase net loss per share. The exercise of share options
does not increase the basic loss per share and therefore the basic and diluted
loss per share remain the same.

The calculation of basic loss per ordinary share is based on a loss of £915,661
(2003 - £414,051) and on 37,878,653 (2003 - 26,103,565) ordinary shares being
the weighted average number of ordinary shares in issue during the year.


RECONCILIATION OF MOVEMENTS IN SHAREHOLDERS' FUNDS AND STATEMENT OF MOVEMENTS ON RESERVES

Called up Share Share Foreign Profit and
share premium capital to Merger exchange loss
capital account be issued reserve reserve account Total
£ £ £ £ £ £ £

Group
Balance at 1 October 2003 701,230 3,478,203 - (99,900) - (1,769,112) 2,310,421
Loss for the year - - - - - (915,661) (915,661)
Shares issued 343,579 1,761,800 - 2,189,360 - - 4,294,739
Shares to be issued - - 675,817 - - - 675,817
Currency translation
differences on foreign
currency net investments - - - - (8,432) - (8,432)
Costs set against share
premium - (132,485) - - - - (132,485)

Balance at 30 September
2002 1,044,809 5,107,518 675,817 2,089,460 (8,432) (2,684,773) 6,224,399

Company
Balance at 1 October 2003 701,230 3,478,203 - - - (229,895) 3,949,538
Loss for the year - - - - - (410,496) (410,496)
Shares issued 343,579 1,761,800 - 2,189,360 - - 4,294,739
Shares to be issued - - 675,817 - - - 675,817
Costs set against share
premium - (132,485) - - - - (132,485)

Balance at 30 September
2002 1,044,809 5,107,518 675,817 2,189,360 - (640,391) 8,377,113


Share capital to be issued represents Deferred Contingent Consideration in
relation to the acquisition of Clinomics Biosciences Inc.



NET CASH OUTFLOW FROM OPERATING ACTIVITIES
2004 2003
£ £

Operating loss (972,256) (334,095)
Depreciation charge 260,389 196,350
Loss on disposal of fixed assets 1,150 -
Amortisation of goodwill and intangibles 204,953 63,016
Exceptional restructuring costs - (118,086)
Decrease (increase) in debtors 333,737 (658,770)
Increase in stocks (102,016) (160,803)
Increase in creditors 151,414 92,169

Net cash outflow from operating activities (122,629) (920,219)


ANALYSIS OF CASH FLOWS FOR HEADINGS NETTED IN THE CASH FLOW STATEMENT
2004 2003
£ £
Returns on investments and servicing of finance
Interest received 22,124 7,592
Interest paid (7,227) (32,328)
Interest element of finance lease rental payments (39,733) -

Net cash outflow from returns on investments and servicing of finance (24,836) (24,736)

Taxation
Research and development tax credit 58,338 10,880

Capital expenditure and financial investment
Payments to acquire tangible fixed assets (512,972) (57,073)
Receipts from the sale of fixed assets 6,611 -
Payments to acquire intangible fixed assets (111,394) (16,929)

Net cash outflow from capital expenditure and financial investment (617,755) (74,002)

Acquisitions
Purchase of trade and assets of Cambridge BioScience Limited - (319,982)
Purchase of trade and assets of Cytocell Limited - (50,000)
Purchase of Clinomics Biosciences Inc (236,460) -
Overdraft acquired with subsidiary (6,543) -

(243,003) (369,982)

Management of liquid resources
Increase in short-term investments (450,000) -

Financing
Proceeds from issue of ordinary share capital 1,915,000 2,269,000
Cost of issuing ordinary share capital (132,485) (451,178)
Capital element of finance lease rental repayments (44,142) (24,320)
Repayment of loan notes (365,464) (25,000)
New bank loan - 100,000

Net cash inflow from financing 1,372,909 1,868,502




ANALYSIS OF CHANGES IN NET DEBT

Acquisition
At 1 excluding Other At 30
October Cash cash and non-cash September
2003 flows overdraft changes 2004

£ £ £ £ £

Cash at bank and in hand 414,529 (26,976) - - 387,553

Debt due after one year (1,145,000) 224,103 (17,428) 83,025 (855,300)
Debt due within one year (110,000) 141,361 (31,361) (83,025) (83,025)
Finance leases (71,356) 44,142 - (34,129) (61,343)

(1,326,356) 409,606 (48,789) (34,129) (999,668)

Short term investment - 450,000 - - 450,000

Net debt (911,827) 832,630 (48,789) (34,129) (162,115)



This information is provided by RNS
The company news service from the London Stock Exchange
Posted at 30/9/2004 16:21 by irshaad
Director dealing, looks ready to rock and ROLL!!!!1
Posted at 13/1/2004 09:50 by ozgem
Correct.It is down on yesterdays close which is what I considered worst case scenario.I am hoping now this will create more upward pressure on the share price as the squeeze will be on to get some of these and eliminate the large spread that puts some investors off the 1 penny shares.
Posted at 02/1/2004 14:44 by james t kirk
I think a couple of the 1.7p trades may be sells as the bid touched there earlier. In particular the 1mill looks like a sell, which probably forced the bid back down.

Smaller investors still buying steadily, we're still moving in a very nice northwards motion.
Posted at 02/1/2004 10:07 by czar
A couple of things are happening here, firstly the enlarged group is expected to start to make serious profits, although i can't find any recent forecasts, and secondly the larger market cap and consolidation out of the penny share level is designed to attract institutional investors. A biotech that can make money and may be on a single figure pe will be extremely attractive. I found it very encouraging that they had no trouble placing 200m shares at 1.25p even though the price was down at 1.1p, you have to assume these people did their research, at least they will know more than us. You don't hear the term "ten bagger" these days but this could just be one, even a five bagger would be great.
Posted at 29/12/2003 15:59 by robertap
ozgem,
6.128x10^6 are being taken by institutional and other investors plus 7.6x10^6 for Clinomics purchase. These will be traded as of 13th Jan'y 2004 i.e a potential of nearly 14 million NEW ordinary shares (equivalent to 350 million shares at today's par value)
I am therefore as suprised as you by the recent increase. I would have thought there might be a small premium, say 10% but not 30% as it is at the moment

My thoughts only. But others may have a different view.

DYOR
Posted at 08/10/2003 17:29 by optimist23
As it is October now and several blocks of stock are changing hands I feel that it is time for a new thread.

Again big delayed buy and sells have been pouring in after close.

I believe that the price has continue to risen as someone is building a stake here. I think that the stock is not being accumalated on the open market hence the price doesn't seem to fall on the big sells. What is happening is the buyer is gathering stock from institutions etc. Where the big sell is followed with the big buy. IMHO.

Not the usual retail investors buying and selling so expecting interesting times ahead for the rest of October as the picture becomes clearer.
Posted at 08/10/2003 14:51 by optimist23
some pretty large buys which is moving the price. Not many retail investors having a dabble
Posted at 12/9/2003 09:58 by sandbank
The real problem with CYX is lack of newsflow - positive or negative. Whoever's in charge of their PR should be fired. Investors need to know what a company is actually doing - but the web site news section hasn't been updated since March (infact if you link to it from ADVFN you get the Cambridge Biosciences web site instead). Hopeless.
Posted at 15/8/2003 16:27 by bmont
Sitting on the sidelines and warming the bench is never any fun. It seems that after months of uncertainties, recently released data shows that investors are starting to get back into the game. This indicates that investors are becoming more optimistic about the market's performance in the next few months. In order to forge ahead with renewed confidence, register your email address with this newsletter. It will point you in the right direction by notifying you when an undervalued stock is about to move. It's free and you can cancel at any time. These shares are traded in the US markets.

Your Recent History

Delayed Upgrade Clock