Holding(s) in Company

RNS Number:9105R
Cyprotex PLC
22 February 2002

                                  SCHEDULE 10

                   NOTIFICATION OF MAJOR INTERESTS IN SHARES


1)   Name of company


     Cyprotex plc

2)   Name of shareholder having a major interest


     Dresdner Kleinwort Wasserstein Group Limited

3)   Please state whether notification indicates that it is in respect of
     holding of the shareholder named in 2 above or in respect of a
     non-beneficial interest or in the case of an individual holder if it is
     a holding of that person's spouse or children under the age of 18


     As above

4)   Name of the registered holder(s) and, if more than one holder, the
     number of shares held by each of them


     Dresdner Kleinwort Wasserstein Securities Limited

5)   Number of shares/amount of stock acquired


     750,000

6)   Percentage of issued class


     0.83

7)   Number of shares/amount of stock disposed


     N/A

8)   Percentage of issued class


     N/A

9)   Class of security


     Ordinary Shares of 0.1 pence each


10)  Date of transaction


     18 February 2002

11)  Date company informed


     19 February 2002

12)  Total holding following this notification


     17,809,465

13)  Total percentage holding of issued class following this notification


     19.70


14)  Any additional information


     N/A

15)  Name of contact and telephone number for queries


     Paul Lines - 0161 831 9133

16)  Name and signature of authorised company official responsible for
     making this notification


    _______________________

     John Nicholson
     Chief Operating Officer

     Date of notification 22 February 2002



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