Holding(s) in Company

RNS Number:5504X
Cobra Bio-Manufacturing PLC
13 April 2004

                                  SCHEDULE 10

                   NOTIFICATION OF MAJOR INTERESTS IN SHARES


1.     Name of company

       Cobra Bio-Manufacturing plc

2.     Name of shareholder having a major interest

       Standard Life Investments

3.     Please state whether notification indicates that it is in respect of holding of the shareholder named in 2 above
       or in respect of a non-beneficial interest orin the case of an individual holder if it is a holding of that
       person's spouse or children under the age of 18.

       As above

4.     Name of the registered holder(s) and, if more than one holder, the number of shares held by each of them

       StanLife Nominees Limited

5.     Number of shares/amount of stock acquired

       N/A

6.     Percentage of issued class

       N/A

7.     Number of shares/amount of stock disposed

       75,000

8.     Percentage of issued class

       Not stated

9.     Class of security

       Ordinary 10p shares

10.    Date of transaction

       8 April 2004

11.    Date company informed

       13 April 2004

12.    Total holding following this notification

  710,000 Ordinary Shares

13.    Total percentage holding of issued class following this notification

       3.641%

14.    Any additional information

15.    Name of contact and telephone number for queries

       Tracey Pughe 01782 877293

16.    Name and signature of authorised company official responsible for making this notification.

       Tracey Pughe

Date of notification: 13 April 2004




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