Holding(s) in Company

    rRNS Number:9312S
Cobra Bio-Manufacturing PLC
14 March 2007



TR-1: NOTIFICATION OF MAJOR INTERESTS IN SHARES

1. Identity of the issuer or the underlying issuer of existing shares to which
voting rights are attached:

Cobra Biomanufacturing Plc

2. Reason for the notification (please place an X inside the appropriate 
bracket/s):

An acquisition or disposal of voting rights:                                 ( )

An acquisition or disposal of financial instruments which may result in the
acquisition of shares already issued to which voting rights are attached:    ( )

An event changing the breakdown of voting rights:                            ( )

Other (please specify) :                                                     (X)

Initial notification of shareholding under the Transparency Directive

3. Full name of person(s) subject to the notification obligation:

Barclays PLC

4. Full name of shareholder(s) (if different from 3.) :

Barclays Stockbrokers Limited
Gerrard Limited

5. Date of the transaction (and date on which the threshold is crossed or
reached if different):

8 March 2007

6. Date on which issuer notified:

9 March 2007

7. Threshold(s) that is/are crossed or reached:

N/A

8. Notified details:

A: Voting rights attached to shares

Class/type of shares if possible using    Situation previous to the Triggering
the ISIN CODE                             transaction


                                          Number of       Number of voting
                                          shares          Rights


ISIN                                      1,020,477       1,020,477
GB0031704835



Resulting situation after the triggering transaction

Class/type of shares if     Number of   Number of voting     % of voting
possible using the ISIN     shares      rights               rights
CODE

                                        Direct   Indirect    Direct   Indirect


                            1,024,402   0        1,024,402                5.23%

B: Financial Instruments

Resulting situation after the triggering transaction

Type of      Expiration Exercise/     Number of voting rights that may   % of
financial    Date       Conversion    be acquired if the instrument is   voting
instrument              Period/       exercised/ converted.              rights
                        Date



Total (A+B)


Number of voting rights                      % of voting rights


1,024,402                                    5.23%

9. Chain of controlled undertakings through which the voting rights and/or the
financial instruments are effectively held, if applicable :

Barclays Stockbrokers Limited


Gerrard Limited

Proxy Voting:

10. Name of the proxy holder:

..........

11. Number of voting rights proxy holder will cease to hold:

..............
12. Date on which proxy holder will cease to hold voting rights:

................

13. Additional information:

.............

14. Contact name:

Peter Coleman

15. Contact telephone number:

01782 714181


                      This information is provided by RNS
            The company news service from the London Stock Exchange

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