Holding(s) in Company

RNS Number:6435U
Acambis PLC
26 January 2004



Acambis plc ("the Company")

DISCLOSURE OF INTEREST

The Company received notification on 23 January 2004 that Aviva plc and Morley
Fund Management Limited (a subsidiary of Aviva plc) have a material interest of
5,867,927 Ordinary shares of 10p each in the Company, representing 5.55% of the
issued share capital of the Company.

The notification was prompted by the transfer of stock from material funds to
funds not classed as material on 21 January 2004.



The shares are registered as follows:

REGISTERED HOLDERS                                            NO. OF SHARES HELD
BNY Norwich Union Nominees Ltd                              833,266   (Material)
Chase GA Group Nominees Ltd                                 3,367,279 (Material)
Chase Nominees Ltd                                          323,474   (Material)
CUIM Nominee Ltd                                            1,157,925 (Material)
RBSTB Nominees Ltd                                          185,983   (Material)

Total Material Holding                                      5,867,927



Aviva plc is only required to notify interests which are defined as material
interests when the holding is equal to 3% or more of the Company's relevant
share capital. The term material interests excludes certain categories where
Aviva plc does not hold a beneficial interest, for example where the shares are
held in an Authorised Unit Trust Scheme or Open Ended Investment Company.
Holdings in those categories are therefore not included in the holding notified
to the Company.






                      This information is provided by RNS
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