Directorate Change

RNS Number:8350L
Profile Therapeutics PLC
03 June 2003


For Immediate Release:                                      07:30, 3rd June 2003

                            Profile Therapeutics plc

                              Directorate Change

Profile Therapeutics plc ("Profile"), which develops and commercialises
specialist inhaled therapies to improve the treatment of respiratory patients,
today announces that Mark Kirby, currently Executive Chairman, will become
Non-Executive Chairman of the Board as of 2nd June 2003.

Mark Kirby, Chairman of Profile, commenting on this move, said:

"It was always our intention that I should take a lower profile role within the
Group as soon as the newly formed Executive Management team was firmly
established.  The Executive team is now strong, working well together and
entirely up to speed with the running of the Business and the strategy for
taking it forward.  I am therefore confident that my decision to take a step
back to a non-executive role is the right one - while remaining totally
committed to Profile."

                                     -ENDS-

For further information, please call:

Profile Therapeutics
Mark Kirby, Chairman                                        Today 07785 241046 Thereafter:  0870 770 2000
John Lisle, Chief Executive Officer                                                         0870 770 2000

Buchanan Communications                                                               Tel:  [phone]
Nicola How / James Strong


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