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SRA Serono S A

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Share Name Share Symbol Market Type
Serono S A NYSE:SRA NYSE Ordinary Share
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  0.00 0.00% 0.00 -

Merck Serono: REFLEX Study Results Show Treatment With Rebif(R) Delays Conversion to MS in Patients With First Clinical Signs of

25/10/2010 10:19am

PR Newswire (US)


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GENEVA, October 25, 2010 /PRNewswire/ -- Merck Serono, a division of Merck KGaA, Darmstadt, Germany, announced today that the two-year Phase III REFLEX 1 study met its primary endpoint by demonstrating that Rebif(R) (interferon beta-1a) significantly delayed conversion to multiple sclerosis (MS) diagnosed according to the McDonald criteria 2 in patients with a first clinical event suggestive of the disease.

The international REFLEX study with 517 patients was conducted with the serum-free formulation of Rebif(R) 3, which was first introduced in 2007 and is now available in all European Union countries, Australia, Canada and Switzerland, as well as a number of countries in Asia, Latin America, Africa and the Middle East. The serum-free formulation of Rebif(R) is currently not available in the United States.

The risk of conversion to MS (McDonald criteria) over two years was reduced by 51% (p

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