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RNS Number:2893T M.L. Laboratories PLC 16 December 2003 16 December 2003 PERITONEAL DIALYSIS SOLUTION PRODUCT LAUNCHED IN JAPAN ML Laboratories PLC ("ML") announces that the worldwide licensee of its icodextrin peritoneal dialysis solution, Baxter Healthcare Corporation ("Baxter"), has launched the product in the Japanese market under its trademark 'Extraneal'. The product was approved for marketing earlier this year by the Ministry of Health and Welfare in Japan. Baxter considers Extraneal represents a significant achievement in its continued effort to develop innovative therapies for people with kidney disease. Of the estimated one million people worldwide suffering from chronic kidney disease ("ESRD") who are treated with some form of dialysis therapy, 10 to 15 per cent. use peritoneal dialysis. In Japan, approximately 220,000 ESRD patients are being treated with some form of dialysis. Globally the number of people suffering from ESRD is growing at around 6% per annum. Extraneal is currently approved for marketing in 36 countries and more than 10,000 patients worldwide are using the solution every day. Stuart Sim, Chairman of ML said today: "The Japanese launch of Extraneal represents excellent news as it offers the prospect of significant additional royalty income from this large market". - Ends - For further information please contact: ML Laboratories PLC 01925 844700 Stuart Sim, Executive Chairman Weber Shandwick Square Mile 020 7067 0700 Kevin Smith/Cass Helstrip Note to editors: ML is a pharmaceutical product development company with a track record of successful clinical development, regulatory approval and licensing of pharmaceutical products and a pipeline of future products targeted at specialist markets. ML's activities are supported by a growing income stream from marketed products it has successfully developed and licensed to other pharmaceutical companies, which include Baxter, Shire and Celltech. New therapeutic products in clinical development include cancer treatments, a pain management compound prepared to enter Phase III studies, a preventative of sexually transmitted infections, including HIV, and a phosphate binder to assist the management of kidney failure. ML's portfolio of early stage development projects includes unique polymer/drug molecules to provide safer and more potent cancer chemotherapy and technologies for use in the discovery and manufacture of biotechnology products. In addition ML provides inhaled drug delivery solutions to the global pharmaceutical industry through its dedicated respiratory subsidiary Innovata Biomed. More information on Extraneal can be found at www.baxter.com/extraneal This information is provided by RNS The company news service from the London Stock Exchange END PRLUVAWROORUAAA
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