Rule 8 - Powderject Pharmace

RNS Number:3223L
Amvescap PLC
20 May 2003


                                                                                            FORM 8.1/8.3

Lodge with a RIS or Newstrack if appropriate and the Takeover Panel.  Use a separate form for each class
of securities in which dealings have been made.

Date of Disclosure  20 MAY 2003

DISCLOSURE UNDER RULES 8.1(a), 8.1(b)(i) and 8.3 OF THE CITY CODE ON TAKEOVERS AND MERGERS

Date of dealing  19 MAY 2003

Dealing in ...... POWDERJECT PHARMACEUTICALS PLC ......(name of company).

1)     Class of securities (eg ordinary shares) ..... ORDINARY 10P SHARES.

2)                Amount bought                      Amount sold                  Price per unit
                        -                             1,006,000                       545.00p

3)     Resultant total of the same class owned or controlled (and

       percentage of class) ......... 14,371 .......... (0.01%)

4)     Party making disclosure............... AMVESCAP PLC .................

5)     EITHER       (a)      Name of purchaser/vendor (Note 1) ...................
       OR           (b)      If dealing for discretionary client(s), name of fund management
                             organisation


       ............................. AMVESCAP PLC ..........................

6)     Reason for disclosure (Note 2)
       (a)      associate of         (i)      offeror (Note 3)                       NO
                                     (ii)     offeree company                        NO

       Specify which category or categories of associate (1-8 overleaf)....

       If category (8), explain ...........................................

       (b)      Rule 8.3 (ie disclosure because of ownership or control of 1%

                or more of the class of relevant securities dealt in)      YES

Signed, for and on behalf of the party named in (4) above ..... R.CLYDE ..

(Also print name of signatory) .......... ROBERT CLYDE ....................

Telephone and extension number .......... 020 7065 3720 ...................

Note 1.      Specify owner, not nominee or vehicle company.  If relevant, also

             identify controller of owner, eg where an owner normally acts on instructions of a
             controller.

Note 2.      Disclosure might be made for more than one reason; if so, state all reasons.

Note 3.      Specify which offeror if there is more than one.

Note 4.      When an arrangement exists with any offeror, with the offeree company or with an associate
             of any offeror or of the offeree company in relation to relevant securities, details of
             such arrangement must be disclosed, as required by Note 6 on Rule 8.

Note 5.      It may be necessary, particularly when disclosing derivative transactions, to append a
             sheet to this disclosure form so that relevant information can be given.

Note 6.      In the case of an average price bargain, each underlying trade should be disclosed.


For full details of disclosure requirements, see Rule 8 of the Code.  If in doubt, contact the Panel on
Takeovers and Mergers, Monitoring Section, Tel No: 020 7638 0129. Email: [e-mail]







DEFINITION OF ASSOCIATE

It is not practicable to define associate in terms which would cover all the
different relationships which may exist in an offer. The term associate is
intended to cover all persons (whether or not acting in concert) who directly or
indirectly own or deal in the shares of an offeror or the offeree company in an
offer and who have (in addition to their normal interests as shareholders) an
interest or potential interest, whether commercial, financial or personal, in
the outcome of the offer.

Without prejudice to the generality of the foregoing, the term associate will
normally include the following:-

(1)   an offeror's or the offeree company's parent, subsidiaries and fellow
subsidiaries, and their associated companies, and companies of which such
companies are associated companies (for this purpose ownership or control of 20%
or more of the equity share capital of a company is regarded as the test of
associated company status);

(2)   banks and financial and other professional advisers (including
stockbrokers)* to an offeror, the offeree company or any company covered in (1),
including persons controlling#, controlled by or under the same control as such
banks, financial and other professional advisers;

(3)   the directors (together with their close relatives and related trusts) of
an offeror, the offeree company or any company covered in (1);

(4)   the pension funds of an offeror, the offeree company or any company
covered in (1);

(5)   any investment company, unit trust or other person whose investments an
associate manages on a discretionary basis, in respect of the relevant
investment accounts;

(6)   a person who owns or controls 5% or more of any class of relevant
securities (as defined in paragraphs (a) to (d) in Note 2 on Rule 8) issued by
an offeror or an offeree company, including a person who as a result of any
transaction owns or controls 5% or more. When two or more persons act pursuant
to an agreement or understanding (formal or informal) to acquire or control such
securities, they will be deemed to be a single person for the purpose of this
paragraph. Such securities managed on a discretionary basis by an investment
management group will, unless otherwise agreed by the Panel, also be deemed to
be those of a single person (see Note 8 on Rule 8); and

(7)   a company having a material trading arrangement with an offeror or the
offeree company.

Paragraphs (1)-(7) are typical cases. Paragraph (8) below is a category to cover
associate status not within (1)-(7).

(8)Other.



Notes

* References to a "bank" do not apply to a bank whose sole relationship with a
party to an offer is the  provision of normal commercial banking services or
such activities in connection with the offer as confirming that cash is
available, handling acceptances and other registration work.

References to "financial and other professional advisers (including
stockbrokers)", in relation to a party to an offer, do not include an
organisation which has stood down, because of a conflict of interest or
otherwise, from acting for that party in connection with the offer. If the
organisation is to have a continuing involvement with that party during the
offer, the Panel must be consulted.  Unless the Panel is satisfied that the
involvement is entirely unconnected with the offer, the above exclusion will not
normally apply.

# The normal test for whether a person is controlled by, controls or is under
the same control as another person will be by reference to the definition of
control contained in the Code.  There may be other circumstances which the Panel
will regard as giving rise to such a relationship (eg where a majority of the
equity share capital is owned by another person who does not have a majority of
the voting rights); in cases of doubt, the Panel should be consulted.






                      This information is provided by RNS
            The company news service from the London Stock Exchange
END

DCCAMMTTMMBTBPJ