Aventis (NYSE:AVE)
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Aventis Ships 30 Million Doses of Influenza Vaccine to
Health-Care Providers
Pre-Booked Customers Received Partial or Full Influenza Vaccine Order in
September; Balance to be Shipped in October/November
SWIFTWATER, Pa., Oct. 4 /PRNewswire-FirstCall/ -- Aventis (NYSE:AVE), part of
the sanofi-aventis Group, announced today that the company has shipped more
than 30 million doses of its influenza vaccine, Fluzone(R), Influenza Virus
Vaccine, for the upcoming season. Aventis Pasteur, the human vaccines business
of Aventis, is on schedule to achieving the company's goal of providing Fluzone
vaccine to all its customers in time for the orderly immunization of consumers.
These doses represent the largest shipment of influenza vaccine by any
manufacturer for this influenza season.
"Aventis Pasteur is once again pleased to provide on-schedule delivery of
influenza vaccine, allowing health-care providers to begin immunizing patients
- especially those at greatest risk for influenza-related complications - early
during the immunization season," said Jim Robinson, vice president of
industrial operations for Aventis Pasteur in the U.S.
Aventis Pasteur began to ship Fluzone vaccine in August, one month earlier than
the company originally informed customers. Earlier shipments became possible
due to a strong production year. The company estimates it will produce more
than 52 million doses of Fluzone vaccine for the 2004-05 influenza season.
The 2004-05 influenza vaccine formulation contains the A/Fujian/411/2002
(H3N2)-like, A/New Caledonia/20/99 (H1N1)-like and B/Shanghai/361/2002-like
strains. The three strains for the new influenza vaccine formulation were
confirmed by the Food & Drug Administration (FDA), Center for Biologics
Evaluation & Research, Vaccines & Related Biological Products Advisory
Committee in March 2004. The FDA's decision corresponds with recommendations
made by the World Health Organization in February. Influenza vaccine is
reformulated each year to match the strain predicted to circulate in the coming
season.
For the first time, influenza immunization is now recommended for healthy
children aged 6 through 23 months. These children have been found to be at
increased risk for influenza-related hospitalizations. Children younger than 9
years of age receiving influenza vaccine for the first time require two doses,
one month apart. The vaccine is also recommended for household contacts and
out-of-home caregivers of all children younger than 24 months.
Other groups that have been identified as being at risk for developing serious
influenza-related complications include the elderly, pregnant women and adults
and children with chronic diseases, such as asthma and diabetes. Influenza
vaccination is also recommended for those 50 to 64 years of age, household
contacts of at-risk individuals and health-care workers who care for at-risk
patients.
All other healthy individuals under age 50 and anyone who wishes to decrease
their risk of influenza infection are also encouraged to seek vaccination.
Aventis Pasteur has established a waiting list of providers who request new or
additional influenza vaccine shipments. Health-care providers can place their
name on the waiting list via the company's Web site at
http://www.vaccineshoppe.com/ or by calling 1-800-VACCINE (1-800-822-2463).
Safety Information
The most common side effects from influenza vaccine are pain and swelling at
the vaccination site that can last up to two days. Some people may have mild
fever, myalgia (muscle aches), or feel tired for a day or two after receiving
the influenza vaccine. Other systemic reactions can occur.
Injectable influenza vaccine is made from killed strains of the viruses
predicted to be the main causes of influenza in the coming season. Because the
viruses are killed, it is impossible to get influenza from the vaccine. People
who have had previous reactions to the vaccine or people who are allergic to
eggs (the viruses used in the vaccine are grown in eggs), egg products, or
thimerosal should not receive influenza vaccine. Persons with acute febrile
illness usually should not be vaccinated until their symptoms have abated.
However, minor illnesses with or without fever do not contraindicate the use of
influenza vaccine, particularly among children with mild upper respiratory
tract infection or allergic rhinitis.
For full prescribing information, see the package insert at
http://www.us.aventispasteur.com/.
About sanofi-aventis
The sanofi-aventis Group is the world's 3rd largest pharmaceutical company,
ranking number 1 in Europe. Backed by a world-class R&D organization,
sanofi-aventis is developing leading positions in seven major therapeutic
areas: cardiovascular disease, thrombosis, oncology, diabetes, central nervous
system, internal medicine, vaccines. The sanofi-aventis Group is listed in
Paris (EURONEXT: SAN) and in New York (NYSE:SNY).
Aventis Pasteur, the vaccines business of Aventis, part of the sanofi-aventis
Group, produced 1.4 billion doses of vaccine in 2003, making it possible to
protect 500 million people across the globe, which is about 1.4 million per
day. The company offers the broadest range of vaccines, providing protection
against 20 bacterial and viral diseases. For more information, please visit:
http://www.aventispasteur.com/ .
Forward Looking Statements
Statements in this document containing projections or estimates of revenues,
income, earnings per share, capital expenditures, capital structure, or other
financial items; plans and objectives relating to future operations, products,
or services; future economic performance; or assumptions underlying or relating
to any such statements, are forward-looking statements subject to risks and
uncertainties. Actual results could differ materially depending on factors
such as the timing and effects of regulatory actions, the results of clinical
trials, the company's relative success developing and gaining market acceptance
for new products, the outcome of significant litigation, and the effectiveness
of patent protection. Additional information regarding risks and uncertainties
is set forth in the current Annual Report on Form 20-F of Aventis on file with
the Securities and Exchange Commission and in the current Annual Report
-"Document de Reference"- on file with the "Autorite des marches financiers" in
France.
Web Sites: http://www.vaccineshoppe.com
http://www.aventispasteur.com
http://www.us.aventispasteur.com
DATASOURCE: Aventis Pasteur
CONTACT: Len Lavenda of Aventis Pasteur US Media Relations,
+1-570-839-4446, or ; or Sarah Dumont of Cooney/Waters
Group, +1-212-886-2200, for Aventis Pasteur