Initial Statement of Beneficial Ownership (3)

FORM 3	UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES	OMB APPROVAL OMB Number: 3235-0104 Estimated average burden hours per response... 0.5
	Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940

1. Name and Address of Reporting Person * Loewen Andrea	2. Date of Event Requiring Statement (MM/DD/YYYY) 2/7/2022	3. Issuer Name and Ticker or Trading Symbol REATA PHARMACEUTICALS INC [RETA]
(Last)        (First)        (Middle) 5320 LEGACY DRIVE	4. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director                          _____ 10% Owner ___X___ Officer (give title below)        _____ Other (specify below) SVP, Global Regulatory Affairs /
(Street) PLANO, TX 75024       (City)              (State)              (Zip)	5. If Amendment, Date Original Filed(MM/DD/YYYY)	6. Individual or Joint/Group Filing(Check Applicable Line) _X_ Form filed by One Reporting Person ___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security (Instr. 4)	2. Amount of Securities Beneficially Owned (Instr. 4)	3. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	4. Nature of Indirect Beneficial Ownership (Instr. 5)
Class A common stock	32856 (1)	D

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security (Instr. 4)	2. Date Exercisable and Expiration Date (MM/DD/YYYY)		3. Title and Amount of Securities Underlying Derivative Security (Instr. 4)		4. Conversion or Exercise Price of Derivative Security	5. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 5)	6. Nature of Indirect Beneficial Ownership (Instr. 5)
	Date Exercisable	Expiration Date	Title	Amount or Number of Shares
Employee Stock Option (right to buy)	(2)	2/24/2030	Class A common stock	11250	$196.23	D
Employee Stock Option (right to buy)	(3)	1/4/2031	Class A common stock	9000	$121.29	D
Employee Stock Option (right to buy)	(4)	1/3/2032	Class A common stock	50000	$27.32	D

Explanation of Responses:
(1)	The shares represent 543 shares of Class A common stock; 750 Restricted Stock Units (RSU), which vest in equal installments on April 26, 2022, April 26, 2023, and April 26, 2024, subject to continued service through each vesting date; 4,500 RSUs, which vest in equal installments on March 6, 2022, March 6, 2023, March 6, 2024, and March 6, 2025, subject to continued service through each vesting date; 2,250 RSUs, which vest in equal installments on March 1, 2022, March 1, 2023, and March 1, 2024, subject to continued service through each vesting date; and 25,000 RSUs, which vest in equal installments on March 6, 2023, March 6, 2024, March 6, 2025, and March 6, 2026, subject to continued service through each vesting date.
(2)	The options vest 25% on February 24, 2021 and in 12 equal quarterly installments thereafter, subject to continued service through each vesting date.
(3)	The options vest in sixteen equal quarterly installments beginning on April 4, 2021, subject to continued service through each vesting date.
(4)	The options vest in sixteen equal quarterly installments beginning on April 3, 2022, subject to continued service through each vesting date.

Remarks: Exhibit List: Exhibit 24 - Power of Attorney

Reporting Owners
Reporting Owner Name / Address	Relationships
	Director	10% Owner	Officer	Other
Loewen Andrea 5320 LEGACY DRIVE PLANO, TX 75024			SVP, Global Regulatory Affairs

Signatures
/s/ Tracy Herson, attorney-in-fact		2/7/2022
**Signature of Reporting Person		Date