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Share Name | Share Symbol | Market | Type |
---|---|---|---|
Portola Pharmaceuticals Inc | NASDAQ:PTLA | NASDAQ | Common Stock |
Price Change | % Change | Share Price | Bid Price | Offer Price | High Price | Low Price | Open Price | Shares Traded | Last Trade | |
---|---|---|---|---|---|---|---|---|---|---|
0.00 | 0.00% | 18.03 | 18.00 | 18.10 | 0 | 01:00:00 |
Oral Presentation Details:• Presentation Title: Effect of Andexanet-TFPI Interaction on in Vitro Thrombin Formation and Coagulation Markers in the TF-Pathway
Poster Presentation Details:
• Poster Title: Physiologically-Based Pharmacokinetic (PBPK) Modeling for Betrixaban and the Impact of P-glycoprotein Inhibition on Betrixaban Pharmacokinetics
• Poster Title: Impact of D-Dimer Assays Performed at Local Labs vs. Central Laboratory in the Evaluation of APEX Trial Outcomes
• Poster Title: Did Patients with Renal Disease Receive Sufficient Prophylaxis for Venous Thromboembolism in the Real-World Settings?: A Study Among Hospitalized Acutely Medically Ill Patients
• Poster Title: The Frequency of Venous Thromboembolism (VTE) Prophylaxis Among Patients Hospitalized for Cancer in the US
• Poster Title: Cerdulatinib Pharmacodynamics and Relationships to Tumor Response Following Oral Dosing in Patients with Relapsed/Refractory B Cell Malignancies: Results from a Phase I Dose Escalation Study
Important U.S. Safety Information for Bevyxxa (betrixaban) capsulesINDICATION Bevyxxa is indicated for the prophylaxis of venous thromboembolism (VTE) in adult patients hospitalized for an acute medical illness who are at risk for thromboembolic complications due to moderate or severe restricted mobility and other risk factors for VTE. LIMITATIONS OF USE The safety and effectiveness of Bevyxxa have not been established in patients with prosthetic heart valves because this population has not been studied. SELECT IMPORTANT SAFETY INFORMATION ___________________________________________________________________________________________________________________________________________________ WARNING: SPINAL/EPIDURAL HEMATOMAEPIDURAL OR SPINAL HEMATOMAS MAY OCCUR IN PATIENTS TREATED WITH BEVYXXA WHO ARE RECEIVING NEURAXIAL ANESTHESIA OR UNDERGOING SPINAL PUNCTURE. THE RISK OF THESE EVENTS MAY BE INCREASED BY THE USE OF IN‑DWELLING EPIDURAL CATHETERS OR THE CONCOMITANT USE OF MEDICAL PRODUCTS AFFECTING HEMOSTASIS. THESE HEMATOMAS MAY RESULT IN LONG-TERM OR PERMANENT PARALYSIS. CONSIDER THESE RISKS WHEN SCHEDULING PATIENTS FOR SPINAL PROCEDURES. ___________________________________________________________________________________________________________________________________________________
CONTRAINDICATIONS
WARNINGS AND PRECAUTIONS Risk of Bleeding
Spinal/Epidural Anesthesia or Puncture
Use in Patients with Severe Renal Impairment
Use in Patients on Concomitant P-glycoprotein (P-gp) Inhibitors
ADVERSE REACTIONS
USE IN SPECIFIC POPULATIONS Hepatic Impairment
Please see additional Important Safety Information and full Prescribing Information, including the Boxed Warning at Bevyxxa.com About Portola Pharmaceuticals, Inc.Portola Pharmaceuticals is a biopharmaceutical company developing product candidates that could significantly advance the fields of thrombosis and other hematologic diseases. The Company’s first medicine Bevyxxa® (betrixaban), an oral, once-daily Factor Xa inhibitor, was approved by the U.S. Food and Drug Administration in June 2017. The company is also working to advance two clinical programs for andexanet alfa, a recombinant protein designed to reverse the anticoagulant effect in patients treated with an oral or injectable Factor Xa inhibitor; and cerdulatinib, a SYK/JAK inhibitor in development to treat hematologic cancers. Portola's partnered program is focused on developing selective SYK inhibitors for inflammatory conditions. For more information, visit http://www.portola.com and follow the Company on Twitter @Portola_Pharma. Forward-Looking StatementsThis announcement contains forward-looking statements, including statements relating to Portola Pharmaceuticals’ expectations regarding the anticipated product availability of Bevyxxa. These statements are subject to significant risks and uncertainties and actual results could differ materially from those projected. Portola Pharmaceuticals cautions investors not to place undue reliance on the forward-looking statements contained in this release. These risks and uncertainties include, without limitation, risks and uncertainties related to regulatory review and our manufacturing and distribution strategy. There can be no assurance that Portola Pharmaceuticals will be able to make Bevyxxa commercially available on our anticipated timeline. Risks and uncertainties relating to Portola Pharmaceuticals and its business can be found in the “Risk Factors” section of Portola Pharmaceuticals’ Quarterly Report on Form 10-Q for the third quarter of 2017, which was filed with the SEC on November 9, 2017. Portola Pharmaceuticals undertakes no duty or obligation to update any forward-looking statements contained in this release as a result of new information, future events or changes in Portola Pharmaceuticals’ expectations.
Investor Contact: | Media Contact: |
Michele Mantynen | Patrick Ryan |
Portola Pharmaceuticals | W2O Group |
ir@portola.com | pryan@w2ogroup.com |
1 Year Portola Pharmaceuticals Chart |
1 Month Portola Pharmaceuticals Chart |
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