PRAECIS PHARMACEUTICALS INCORPORATED To Announce Third Quarter 2005 Financial Results on Friday, November 4, 2005

PRAECIS PHARMACEUTICALS INCORPORATED (NASDAQ:PRCS),
today announced that it will report Third Quarter 2005 financial
results on Friday, November 4, 2005, before the financial markets
open. Company management will host a conference call beginning at 9:00
a.m., EST, with members of the investment community.
   The Company's conference call may be accessed live by visiting
PRAECIS' website at http://www.praecis.com under "Investors" and
"Webcast Live." Interested parties also may listen to a replay of the
call beginning Friday, November 4, at 12:00 Noon (EST), until midnight
Friday, November 11, by calling 888-203-1112 or 719-457-0820, and
entering the passcode 175611.

   PRAECIS PHARMACEUTICALS INCORPORATED is a biopharmaceutical
company focused on the discovery, development and commercialization of
innovative therapies that either address unmet medical needs or offer
improvements over existing therapies. PRAECIS has a novel MetAP-2
inhibitor in clinical development for non-Hodgkin's lymphoma and solid
tumors, as well as an innovative drug discovery technology, Direct
Select(TM), which enables the generation and practical use of
ultra-large libraries for the discovery of orally active compounds for
drug development. PRAECIS has received approval to market Plenaxis(R)
in both the United States and Germany.