Initial Statement of Beneficial Ownership (3)

FORM 3	UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES	OMB APPROVAL OMB Number: 3235-0104 Estimated average burden hours per response... 0.5
	Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940

1. Name and Address of Reporting Person * Rhodes William E.	2. Date of Event Requiring Statement (MM/DD/YYYY) 4/1/2020	3. Issuer Name and Ticker or Trading Symbol OPGEN INC [OPGN,OPGNW]
(Last)        (First)        (Middle) C/O OPGEN, INC. 708 QUINCE ORCHARD ROAD, SUITE 205	4. Relationship of Reporting Person(s) to Issuer (Check all applicable) __X__ Director                          _____ 10% Owner _____ Officer (give title below)        _____ Other (specify below)
(Street) GAITHERSBURG, MD 20878       (City)              (State)              (Zip)	5. If Amendment, Date Original Filed(MM/DD/YYYY)	6. Individual or Joint/Group Filing(Check Applicable Line) _X_ Form filed by One Reporting Person ___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security (Instr. 4)	2. Amount of Securities Beneficially Owned (Instr. 4)	3. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	4. Nature of Indirect Beneficial Ownership (Instr. 5)

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security (Instr. 4)	2. Date Exercisable and Expiration Date (MM/DD/YYYY)		3. Title and Amount of Securities Underlying Derivative Security (Instr. 4)		4. Conversion or Exercise Price of Derivative Security	5. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 5)	6. Nature of Indirect Beneficial Ownership (Instr. 5)
	Date Exercisable	Expiration Date	Title	Amount or Number of Shares
Nonqualified Stock Option (Right to Buy)	(1)(2)	6/16/2026	Common Stock	1439	$56.38	D
Nonqualified Stock Option (Right to Buy)	(1)(3)	6/16/2026	Common Stock	959	$52.78	D
Nonqualified Stock Option (Right to Buy)	(1)(4)	6/16/2026	Common Stock	959	$8.57	D

Explanation of Responses:
(1)	These options were originally granted pursuant to the Curetis Stock Option Plan 2016, as amended on July 19, 2018, which Plan was assumed by OpGen, Inc. (the "Company") as the Amended and Restated Stock Option Plan on April 1, 2020, upon the closing of the transactions contemplated by that certain Implementation Agreement, dated September 4, 2019, by and among the Company, Curetis N.V. and Crystal GmhH, and the stock options converted into options to acquire common stock of OpGen.
(2)	This option was originally granted on July 1, 2016 and vested over a period of three (3) years with the first third (1/3) vesting on the first anniversary of the date of grant and the remaining two thirds (2/3) vesting in monthly increments over the following twenty-four (24) months.
(3)	This option was originally granted on July 1, 2018 and vests over a period of three (3) years with the first third (1/3) vesting on the first anniversary of the date of grant and the remaining two thirds (2/3) vesting in monthly increments over the following twenty-four (24) months.
(4)	This option was originally granted on July 1, 2019 and vests over a period of three (3) years with the first third (1/3) vesting on the first anniversary of the date of grant and the remaining two thirds (2/3) vesting in monthly increments over the following twenty-four (24) months.

Remarks: Exhibit List: Exhibit 24 - Power of Attorney

Reporting Owners
Reporting Owner Name / Address	Relationships
	Director	10% Owner	Officer	Other
Rhodes William E. C/O OPGEN, INC. 708 QUINCE ORCHARD ROAD SUITE 205 GAITHERSBURG, MD 20878	X

Signatures
/s/ William E. Rhodes		4/10/2020
**Signature of Reporting Person		Date