Holding(s) in Company

RNS Number:4975T
Isotron PLC
19 December 2003


                                   SCHEDULE 10
 
                    NOTIFICATION OF MAJOR INTERESTS IN SHARES


1)   NAME OF COMPANY

     ISOTRON PLC


2)   NAME OF SHAREHOLDER HAVING A MAJOR INTEREST

     LEGAL & GENERAL PLC


3)   Please state whether notification indicates that it is in respect of 
     holding of the Shareholder named in 2 above or in respect of a 
     non-beneficial interest or in the case of an individual holder if it is a
     holding of that person's spouse or children under the age of 18

     2 ABOVE


4)   Name of the registered holder(s) and, if more than one holder, the 
     number of shares held by each of them.

     HSBC GLOBAL CUSTODY NOMINEE (UK) LTD A/C's 914945, 887711, 775245, 357206,
     747381, 363605, 866203, 360509


5)   Number of shares/amount of stock acquired.
     
     161404


6)   Percentage of issued Class

     0.76%

7)   Number of shares/amount of stock disposed


8)   Percentage of issued Class


9)   Class of security

     25P ORD SHARES


10)  Date of transaction

     16.12.03


11)  Date company informed

     19.12.03


12)  Total holding following this notification

     914309

               
13)  Total percentage holding of issued class following this notification

     4.33


14)  Any additional information



15)  Name of contact and telephone number for queries

     P WYNNE
     01793 567913/567903


16)  Name and signature of authorised company official responsible for 
     making this notification

     Date of Notification     19.12.2003



                      This information is provided by RNS
            The company news service from the London Stock Exchange

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