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Share Name | Share Symbol | Market | Type |
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Neuralstem Inc | NASDAQ:CUR | NASDAQ | Common Stock |
Price Change | % Change | Share Price | Bid Price | Offer Price | High Price | Low Price | Open Price | Shares Traded | Last Trade | |
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0.00 | 0.00% | 1.52 | 1.58 | 1.62 | 0 | 01:00:00 |
- NSI-566 shown to have restorative function in primate paralysis model -
The manuscript, entitled ‘Restorative Effects of Human Neural Stem Cell Grafts on the Primate Spinal Cord,’ involved a study to evaluate the potential benefits of transplanting NSI-566 into rhesus monkeys two weeks after they received a hemisection lesion of the cervical spinal cord.
Key Findings:
The study was led by researchers at the University of California San Diego School of Medicine and builds on their previous work showing that grafted NSI-566 cells promote locomotor recovery in rats subjected to severe spinal cord injury.
“This study strengthens our conviction that NSI-566 could potentially confer a benefit in patients with motor deficits from spinal injury and supports our ongoing efforts in addressing conditions involving paralysis, such as ALS and stroke," said Richard Daly, Neuralstem’s Chairman and CEO.
About NSI-566
Neuralstem’s stem cell therapy product candidate, NSI-566, is a spinal cord-derived neural stem cell line. Neuralstem is currently evaluating NSI-566 in three indications: ischemic stroke, Amyotrophic Lateral Sclerosis (ALS), and chronic spinal cord injury (cSCI).
Neuralstem is conducting a Phase 1 safety study for the treatment of paralysis from chronic motor stroke at the BaYi Brain Hospital in Beijing, China. In addition, NSI-566 was evaluated in a Phase 1 safety study to treat paralysis due to chronic spinal cord injury as well as Phase 1 and Phase 2a dose escalation, safety trials for ALS. Subjects from all three indications are currently in long-term observational follow-up periods to continue to monitor safety and possible therapeutic benefits.
About Neuralstem
Neuralstem is a clinical-stage biopharmaceutical company developing novel treatments for nervous system diseases of high unmet medical need. The Company has two lead development candidates:
Neuralstem’s diversified portfolio of product candidates is based on its proprietary neural stem cell technology.
Cautionary Statement Regarding Forward Looking Information
This news release contains “forward-looking statements” made pursuant to the “safe harbor” provisions of the Private Securities Litigation Reform Act of 1995. Such forward-looking statements relate to future, not past, events and may often be identified by words such as “expect,” “anticipate,” “intend,” “plan,” “believe,” “seek” or “will.” Forward-looking statements by their nature address matters that are, to different degrees, uncertain. Specific risks and uncertainties that could cause our actual results to differ materially from those expressed in our forward-looking statements include risks inherent in the development and commercialization of potential products, uncertainty of clinical trial results or regulatory approvals or clearances, need for future capital, dependence upon collaborators and maintenance of our intellectual property rights. Actual results may differ materially from the results anticipated in these forward-looking statements. Additional information on potential factors that could affect our results and other risks and uncertainties are detailed from time to time in Neuralstem’s periodic reports, including the Annual Report on Form 10-K for the year ended December 31, 2016, and Form 10-Q for the three and nine months ended September 30, 2017, filed with the Securities and Exchange Commission (SEC), and in other reports filed with the SEC. We do not assume any obligation to update any forward-looking statements.
Contact:
Kimberly MinarovichArgot Partners (Investor Relations)212-600-1902neuralstem@argotpartners.com
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