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CHIR Chiron (MM)

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Chiron to Testify to Congress on Influenza Vaccine

12/02/2004 1:00pm

PR Newswire (US)


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Chiron to Testify to Congress on Influenza Vaccine President and CEO Howard Pien to Appear at U.S. House of Representatives Government Reform Committee Hearing Today EMERYVILLE, Calif., Feb. 12 /PRNewswire-FirstCall/ -- Chiron Corporation today announced that president and chief executive officer Howard Pien will appear before the U.S. House of Representatives Government Reform Committee in Washington, D.C., today as part of an oversight hearing to examine this year's influenza season and pandemic preparedness. Chiron will highlight the importance of strong cooperation between health agencies and private sector companies at all levels. "Chiron is committed to meeting demand for flu vaccine in the United States, today and tomorrow," said Mr. Pien. "Strengthening our public health infrastructure -- to increase immunization rates in the inter-pandemic years -- is the single most important initiative today to prepare for tomorrow's pandemic." Today's hearing will take place immediately following the committee's 10 a.m. EST business meeting. Mr. Pien's testimony will follow those of Dr. Julie Gerberding, director of the Centers for Disease Control and Prevention; Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases; and other witnesses. In a written statement submitted to the committee, Mr. Pien discussed Chiron's commitment to expanding flu vaccine production. Chiron projects that it will produce approximately 50 million doses of Fluvirin(R) flu vaccine in 2004, the vast majority of which will be destined for the United States. If sufficient demand for influenza vaccine exists, Chiron plans to increase its production capacity and supply of influenza vaccine to the United States even further in subsequent seasons. Mr. Pien also discussed Chiron's investment in the development of a cell culture-based flu vaccine and the company's pandemic preparedness plans. The cell-culture vaccine production process offers potential advantages to current egg-based vaccines, including flexibility, and could offer significant benefits in a flu pandemic situation. Chiron's influenza cell-culture research program has completed Phase II clinical trials in Europe. "Chiron is investing in bringing innovation to the U.S. market," said Mr. Pien. "This month we plan to file an IND application for our cell-culture flu vaccine, which is viewed as the best way to defend against a possible future pandemic." In his discussion of the 2003-2004 flu season, Mr. Pien noted that the estimated 83 million Americans immunized represented the highest immunization rate ever for flu, a milestone in public health. He advocated measures to minimize the burden of disease caused by the annual flu epidemic, including an adequate supply of flu vaccine in non-pandemic seasons, appropriate mechanisms to ensure delivery of the vaccine to target populations, and high public awareness of the need for immunization to ensure increased immunization. Chiron produced 38 million doses of Fluvirin for U.S. distribution for the 2003-2004 flu season, approximately 50 percent more than in the previous flu season. In total for the 2003-2004 flu season, Chiron produced 75 million doses of its four brands of flu vaccine for the global market,with production in Liverpool, United Kingdom; Marburg, Germany; and Siena and Rosia, Italy. About 10 to 20 percent of the U.S. population contracts flu each year. Vaccination not only decreases the risk of illness for the vaccine recipient but also helps prevent the spread of the flu virus and limits its role in the potential development of life-threatening complications. In an average year in the United States, flu kills 36,000 people, primarily in the over-65 population, and hospitalizes 114,000 people. About Flu and Chiron's Flu Vaccines Influenza (flu), a contagious disease caused by the influenza virus, affects the respiratory tract, often resulting in symptoms in the nose, throat and lungs, as well as fever, headache, tiredness and body aches. It can also lead to complications such as pneumonia, bronchitis, or sinus and ear infections or exacerbate chronic conditions. In the Northern Hemisphere, flu season typically begins in November and peaks between December and March. Flu vaccination provides protection from flu within about two weeks of administration and may last for as long as a year. The vaccine protects up to 80 percent of vaccinated people from contracting flu, and vaccinated people who do contract flu generally develop milder cases than unvaccinated people. Flu vaccines, the majority of which are made from inactivated (killed) flu strains, are updated each year to address changes in the viruses. People who are allergic to eggs, who have had a severe reaction to a flushot in the past, or who have previously developed Guillain-Barre syndrome in the six weeks after receiving a flu vaccination should consult their doctors before receiving flu vaccination. Chiron Vaccines is the world's second-largest flu vaccines company, with four leading brands. Fluvirin(R) is a triple-antigen flu vaccine, approved for sale in more than two dozen countries including the United States, the United Kingdom, and a number of countries in Europe and the Southern Hemisphere. Outside the United States, Chiron Vaccines markets Agrippal(R) S1, Begrivac(TM) and Fluad(R) flu vaccines. About Chiron Chiron Corporation, headquartered in Emeryville, California, is a global pharmaceutical company that leverages a diverse business model to develop and commercialize high-value products that make a difference in people's lives. The company has a strategic focus on cancer and infectious disease. Chiron applies its advanced understanding of the biology of cancer and infectious disease to develop products from its platforms in proteins, small molecules and vaccines. The company commercializes its products through three business units: BioPharmaceuticals, Vaccines and Blood Testing. For more information about Chiron, visit the company's website at http://www.chiron.com/. This news release contains forward-looking statements, including statements regarding product development initiatives, capital investments, sales growth and new product marketing that involve risks and uncertainties andare subject to change. A full discussion of the company's operations and financial condition, including factors that may affect its business and future prospects, is contained in documents the company has filed with the SEC, including the form 10-Q for the quarter ended September 30, 2003, and the form 10-K for the year ended December 31, 2002, and will be contained in all subsequent periodic filings made with the SEC. These documents identify important factors that could cause the company's actualperformance to differ from current expectations, including product development activities such as clinical trials, manufacturing capabilities, intellectual property protections and defenses, stock-price and interest-rate volatility, and marketing effectiveness. In particular, there can be no assurance that Chiron will increase sales of existing products, successfully develop and receive approval to market new products, or achieve market acceptance for such new products. Consistent with SEC Regulation FD, we do not undertake an obligation to update the forward-looking information we are giving today. NOTE: Fluvirin, Agrippal, Begrivac and Fluad are trademarks of Chiron Corporation. DATASOURCE: Chiron Corporation CONTACT: Chiron Corporate Communications & Investor Relations, media, +1-510-923-6500, or investors, +1-510-923-2300 Web site: http://www.chiron.com/

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