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Share Name | Share Symbol | Market | Type |
---|---|---|---|
AnaptysBio Inc | NASDAQ:ANAB | NASDAQ | Common Stock |
Price Change | % Change | Share Price | Bid Price | Offer Price | High Price | Low Price | Open Price | Shares Traded | Last Trade | |
---|---|---|---|---|---|---|---|---|---|---|
-0.17 | -0.46% | 37.06 | 20.00 | 38.00 | 38.85 | 36.89 | 37.71 | 288,205 | 23:41:03 |
“We are excited with our recently released Phase 1 trial results of ANB032, our anti-BTLA agonist, and the potential to broadly treat T and B-cell driven inflammatory diseases. Our recently initiated strategic portfolio review will define the path forward across a breadth of clinical development options of potential inflammation-focused indications that could be pursued for each of our clinical and preclinical therapeutic antibody programs,” said Daniel Faga, interim president and chief executive officer of AnaptysBio. “We look forward to continuing to execute on our ongoing clinical trials with multiple readouts throughout the next 18 months.”
Imsidolimab (Anti-IL-36 receptor) Program
Rosnilimab (Anti-PD-1 agonist) Program
ANB032 (Anti-BTLA agonist) Program
First Quarter Financial Results
About AnaptysBio
AnaptysBio is a clinical-stage biotechnology company developing first-in-class antibodies focused on unmet medical needs in inflammation. The Company’s proprietary anti-inflammatory pipeline includes imsidolimab, its anti-IL-36R antibody, previously referred to as ANB019, for the treatment of dermatological inflammatory diseases, including generalized pustular psoriasis, or GPP, and moderate-to-severe hidradenitis suppurativa; rosnilimab, its anti-PD-1 agonist program, previously referred to as ANB030, for the treatment of moderate-to-severe alopecia areata; and its anti-BTLA agonist program, ANB032, which is broadly applicable to human inflammatory diseases associated with lymphoid and myeloid immune cell dysregulation. AnaptysBio’s antibody pipeline has been developed using its proprietary somatic hypermutation, or SHM platform, which uses in vitro SHM for antibody discovery and is designed to replicate key features of the human immune system to overcome the limitations of competing antibody discovery technologies. AnaptysBio has also developed multiple therapeutic antibodies in an immuno-oncology collaboration with GSK, including an anti-PD-1 antagonist antibody (JEMPERLI (dostarlimab-gxly) GSK4057190), an anti-TIM-3 antagonist antibody (cobolimab, GSK4069889) and an anti-LAG-3 antagonist antibody (GSK4074386).
Forward-Looking Statements
This press release contains forward-looking statements within the meaning of the "safe harbor" provisions of the Private Securities Litigation Reform Act of 1995, including, but not limited to: the timing of the release of data from our clinical trials, including imsidolimab’s Phase 3 clinical trial in GPP, Phase 2 clinical trial in hidradenitis suppurativa, and rosnilimab’s Phase 2 clinical trial in alopecia areata; and the timing of ANB032’s IND filing for a Phase 2 clinical trial; and our projected use of our cash resources. Statements including words such as “plan,” “continue,” “expect,” or “ongoing” and statements in the future tense are forward-looking statements. These forward-looking statements involve risks and uncertainties, as well as assumptions, which, if they do not fully materialize or prove incorrect, could cause our results to differ materially from those expressed or implied by such forward-looking statements. Forward-looking statements are subject to risks and uncertainties that may cause the company’s actual activities or results to differ significantly from those expressed in any forward-looking statement, including risks and uncertainties related to the company’s ability to advance its product candidates, obtain regulatory approval of and ultimately commercialize its product candidates, the timing and results of preclinical and clinical trials, the company’s ability to fund development activities and achieve development goals, the company’s ability to protect intellectual property and other risks and uncertainties described under the heading “Risk Factors” in documents the company files from time to time with the Securities and Exchange Commission. These forward-looking statements speak only as of the date of this press release, and the company undertakes no obligation to revise or update any forward-looking statements to reflect events or circumstances after the date hereof.
Contact:Dennis MulroyAnaptysBio, Inc. 858.732.0201dmulroy@anaptysbio.com
AnaptysBio, Inc.Consolidated Balance Sheets (in thousands, except par value data)(unaudited)
March 31, 2022 | December 31, 2021 | ||||||
ASSETS | |||||||
Current assets: | |||||||
Cash and cash equivalents | $ | 166,412 | $ | 495,729 | |||
Receivables from collaborative partners | 921 | 876 | |||||
Short-term investments | 339,209 | 52,368 | |||||
Prepaid expenses and other current assets | 5,869 | 4,903 | |||||
Total current assets | 512,411 | 553,876 | |||||
Property and equipment, net | 2,162 | 2,283 | |||||
Operating lease right-of-use assets | 19,147 | 19,558 | |||||
Long-term investments | 91,195 | 67,097 | |||||
Other long-term assets | 256 | 256 | |||||
Total assets | $ | 625,171 | $ | 643,070 | |||
LIABILITIES AND STOCKHOLDERS’ EQUITY | |||||||
Current liabilities: | |||||||
Accounts payable | $ | 2,481 | $ | 1,741 | |||
Accrued expenses | 15,763 | 12,853 | |||||
Current portion of operating lease liability | 1,537 | 1,505 | |||||
Total current liabilities | 19,781 | 16,099 | |||||
Liability related to sale of future royalties | 255,584 | 251,093 | |||||
Operating lease liability, net of current portion | 19,059 | 19,450 | |||||
Stockholders’ equity: | |||||||
Preferred stock, $0.001 par value, 10,000 shares authorized and no shares, issued or outstanding at March 31, 2022 and December 31, 2021, respectively | — | — | |||||
Common stock, $0.001 par value, 500,000 shares authorized, 28,178 shares and 27,647 shares issued and outstanding at March 31, 2022 and December 31, 2021, respectively | 28 | 28 | |||||
Additional paid in capital | 691,161 | 678,575 | |||||
Accumulated other comprehensive loss | (2,434 | ) | (422 | ) | |||
Accumulated deficit | (358,008 | ) | (321,753 | ) | |||
Total stockholders’ equity | 330,747 | 356,428 | |||||
Total liabilities and stockholders’ equity | $ | 625,171 | $ | 643,070 |
AnaptysBio, Inc. Consolidated Statements of Operations and Comprehensive Loss(in thousands, except per share data) (unaudited)
Three Months EndedMarch 31, | |||||||
2022 | 2021 | ||||||
Collaboration revenue | $ | 970 | $ | 11,247 | |||
Operating expenses: | |||||||
Research and development | 22,516 | 24,185 | |||||
General and administrative | 10,203 | 5,423 | |||||
Total operating expenses | 32,719 | 29,608 | |||||
Loss from operations | (31,749 | ) | (18,361 | ) | |||
Other income (expense), net: | |||||||
Interest income | 342 | 195 | |||||
Non-cash interest expense for the sale of future royalties | (4,854 | ) | — | ||||
Other income, net | 6 | 3 | |||||
Total other income (expense), net | (4,506 | ) | 198 | ||||
Net loss | (36,255 | ) | (18,163 | ) | |||
Unrealized loss on available for sale securities | (2,012 | ) | (107 | ) | |||
Comprehensive loss | $ | (38,267 | ) | $ | (18,270 | ) | |
Net loss per common share: | |||||||
Basic and diluted | $ | (1.31 | ) | $ | (0.66 | ) | |
Weighted-average number of shares outstanding: | |||||||
Basic and diluted | 27,713 | 27,361 |
1 Year AnaptysBio Chart |
1 Month AnaptysBio Chart |
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