Initial Statement of Beneficial Ownership (3)

FORM 3	UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES	OMB APPROVAL OMB Number: 3235-0104 Estimated average burden hours per response... 0.5
	Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940

1. Name and Address of Reporting Person * ROCHE HOLDING LTD	2. Date of Event Requiring Statement (MM/DD/YYYY) 9/24/2021	3. Issuer Name and Ticker or Trading Symbol Jasper Therapeutics, Inc. [JSPR]
(Last)        (First)        (Middle) GRENZACHERSTRASSE 124, 4070	4. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director                          ___X___ 10% Owner _____ Officer (give title below)        _____ Other (specify below)
(Street) BASEL, V8 CH-4070       (City)              (State)              (Zip)	5. If Amendment, Date Original Filed(MM/DD/YYYY)	6. Individual or Joint/Group Filing(Check Applicable Line) ___ Form filed by One Reporting Person _X_ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security (Instr. 4)	2. Amount of Securities Beneficially Owned (Instr. 4)	3. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	4. Nature of Indirect Beneficial Ownership (Instr. 5)
Voting Common Stock	4624606	D (1)

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security (Instr. 4)	2. Date Exercisable and Expiration Date (MM/DD/YYYY)		3. Title and Amount of Securities Underlying Derivative Security (Instr. 4)		4. Conversion or Exercise Price of Derivative Security	5. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 5)	6. Nature of Indirect Beneficial Ownership (Instr. 5)
	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

Explanation of Responses:
(1)	Roche Finance Ltd ("Roche Finance") is the direct beneficial owner of these securities of the Issuer. Roche Finance is a wholly-owned subsidiary of Roche Holding Ltd, a Swiss corporation whose shares are traded on the SIX Swiss Exchange. Roche Holding Ltd is the indirect beneficial owner of these securities of the Issuer.

Reporting Owners
Reporting Owner Name / Address	Relationships
	Director	10% Owner	Officer	Other
ROCHE HOLDING LTD GRENZACHERSTRASSE 124, 4070 BASEL, V8 CH-4070		X
ROCHE FINANCE LTD GRENZACHERSTRASSE 122, 4070 BASEL, V8		X

Signatures
ROCHE FINANCE LTD By: /s/ Beat Kraehenmann Name: Beat Kraehenmann Title: Authorized Signatory		10/4/2021
**Signature of Reporting Person		Date
By: /s/ Carole Nuechterlein Name: Carole Neuchterlein Title: Authorized Signatory		10/4/2021
**Signature of Reporting Person		Date
ROCHE HOLDING LTD By: /s/ Beat Kraehenmann Name: Beat Kraehenmann Title: Authorized Signatory		10/4/2021
**Signature of Reporting Person		Date
By: /s/ Claudia Boeckstiegel Name: Claudia Boeckstiegel Title: Authorized Signatory		10/4/2021
**Signature of Reporting Person		Date