Affymetrix to Host Conference Call on October 27, 2010 to Announce Third Quarter Results

Affymetrix, Inc. (NASDAQ: AFFX) today announced that it will release operating results for the third quarter of 2010 after close of the stock market on Wednesday, October 27, 2010.

The Affymetrix management team will host a conference call on October 27, 2010 at 2:00pm PT to review its operating results for the third quarter. A live webcast can be accessed by visiting the investor relations section of the company’s website at www.affymetrix.com. In addition, investors and other interested parties can listen by dialing 877-407-8291 (domestic) or 201-689-8345 (international).

A replay of this call will be available from 5:00pm PT on October 27, 2010 until 8:00pm PT on November 3, 2010 at the following numbers: 877-660-6853 (domestic), 201-612-7415 (international). The conference identification number for the replays is 359017. An archived webcast of the conference call will be available under the investor relations section of the company's website at www.affymetrix.com.

About Affymetrix

Affymetrix technology is used by the world’s top pharmaceutical, diagnostic and biotechnology companies, as well as leading academic, government and not-for-profit research institutes. More than 2,000 systems have been shipped around the world and more than 22,000 peer-reviewed papers have been published using the technology.

Affymetrix is headquartered in Santa Clara, Calif., and has manufacturing facilities in Cleveland, Ohio, and Singapore. The company has about 1,000 employees worldwide and maintains sales and distribution operations across Europe and Asia. For more information about Affymetrix, please visit the company’s website at www.affymetrix.com.