Holding(s) in Company

RNS Number:4922U
Cytomyx Holdings PLC
21 January 2004


                 Cytomyx Holdings Plc ("Cytomyx" of "Company")

                     Notification of Disclosable Interests


Following the consolidation of the Company's ordinary shares of 0.1p each into
ordinary shares of 2.5p each, the acquisition of Clinomics Biosciences, Inc. and
the placing of 6,128,000 new ordinary shares last week, the Company is aware of
the following interests in its share capital which are required to be disclosed:

                                                        Number of      % of issued
                                                         Ordinary   ordinary share
                                                           shares          capital

Shareholder name

Alan Seeley, Non-executive Director                     6,090,884            14.6%
Stephen Turner, Non-executive Director                  5,288,732            12.7%
Vidacos Nominees Limited Clrlux Acct                    2,994,522             7.2%
Rathbone Nominees Limited                               2,707,000             6.5%
Rathbone Nominees Limited VCT5 Acct                     1,600,000             3.8%
Michael Kerins, Chief Executive                         1,055,000             2.5%
Dr Umesh Anilkumar Patel, Scientific Director             247,500             0.6%
Dr William Thomas Mason, Chairman                         240,000             0.6%
Dr Nicholas George Martin Pay, Non-executive Director      30,600             0.1%



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