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Share Name | Share Symbol | Market | Type |
---|---|---|---|
Philogen Spa | BIT:PHIL | Italy | Ordinary Share |
Price Change | % Change | Share Price | Bid Price | Offer Price | High Price | Low Price | Open Price | Shares Traded | Last Trade | |
---|---|---|---|---|---|---|---|---|---|---|
-0.10 | -0.48% | 20.90 | 20.60 | 21.00 | 21.00 | 20.70 | 20.90 | 2,006 | 17:00:00 |
Philogen Provides Corporate Update
Siena (Italy), 12 November 2021 - Philogen S.p.A., a clinical-stage biotechnology company focused on antibody- and small molecule-based targeted therapeutics provides an update regarding the Company’s Third Quarter Results and recent corporate developments.
Dario Neri, CEO of Philogen, commented on the results for the quarter and the evolution of the business:
"The past few months have been very important for Philogen, and I am delighted to provide an update on our pipeline and our financial position.
Our late-stage candidates Nidlegy™ and Fibromun are progressing well and patient enrolment for their pivotal clinical trials is on track. We are expecting to complete patient enrollment in the melanoma European Phase III clinical trial of Nidlegy™ in mid-2022. The recruitment of patients in Fibromun’s two European clinical studies in newly diagnosed and last-line soft tissue sarcoma is expected to be achieved by the end of 2023.
I am particularly excited about the emerging results in the Phase I/II study of Fibromun as a last-line treatment for glioblastoma, the most common and malignant primary brain tumor. Nine months after the beginning of treatment, the target lesion of the first evaluable patient has disappeared, and we look forward to seeing how long this potent response will last.
I am also pleased to see that we are making progress in the field of small molecule targeted therapeutics beyond OncoFAP-radio conjugates. OncoFAP is a ligand for the delivery of radionuclides and cytotoxic drugs. The excellent targeting performance of OncoFAP in patients with solid tumors was recently validated by PET imaging procedures, and we have now generated new exciting preclinical efficacy data with Small Molecule-Drug Conjugates based on OncoFAP.
Philogen remains committed to developing pharmaceutical products with game changing potential for difficult-to-treat conditions and is well capitalized to pursue this important goal."
MAIN EVENTS AND RECENT HIGHLIGHTS
Proprietary products
Partnered products
FINANCIAL UPDATE
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Philogen Group Description
Philogen is an Italian-Swiss company active in the biotechnology sector, specialized in the research and development of pharmaceutical products for the treatment of highly lethal diseases. The Group mainly discovers and develops targeted anticancer drugs, exploiting high-affinity ligands for tumor markers (also called tumor antigens). These ligands - human monoclonal antibodies or small organic molecules - are identified using Antibody Phage Display Libraries and DNA-Encoded Chemical Library technologies.
The Group's main therapeutic strategy for the treatment of these diseases is represented by the so-called tumor targeting. This approach is based on the use of ligands capable of selectively delivering very potent therapeutic active ingredients (such as pro-inflammatory cytokines) to the tumor mass, sparing healthy tissues. Over the years, Philogen has mainly developed monoclonal antibody-based ligands that are specific for antigens expressed in tumor-associated blood vessels, but not expressed in blood vessels associated with healthy tissues. These antigens are usually more abundant and more stable than those expressed directly on the surface of tumor cells. This approach, so called vascular targeting, is used for most of the projects pursued by the Group.
The Group's objective is to generate, develop and market innovative products for the treatment of diseases for which medical science has not yet identified satisfactory therapies. This is achieved by exploiting (i) proprietary technologies for the isolation of ligands that react with antigens present in certain diseases, (ii) experience in the development of products targeted at the tissues affected by the disease, (iii) experience in drug manufacturing and development, and (iv) an extensive portfolio of patents and intellectual property rights.
Although the Group's drugs are primarily oncology applications, the targeting approach is also potentially applicable to other diseases, such as certain chronic inflammatory diseases.
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FOR MORE INFORMATION:
Philogen - Investor Relations
IR@philogen.com - Emanuele Puca | Investor Relations
Consilium Strategic Communications contacts
Mary-Jane Elliott, Davide Salvi
Philogen@consilium-comms.com
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