Neuro Sector Reviewed by NeuroInvestment

CARDIFF, CA (post-CABG MCI and schizophrenia), Acadia Pharmaceuticals (Parkinson's psychosis), Avigen (MS spasticity), Catalyst Pharmaceuticals (cocaine addiction), Ceregene (Parkinson's), Cortex Pharmaceuticals (AMEX: COR) respiratory depression), EnVivo Pharmaceuticals (schizophrenia and Alzheimer's), Evotec (smoking cessation), Medivation (Huntington's), Neuren (post-CABG MCI), Neurogen (insomnia), Targacept (NASDAQ: TRGT) with AstraZeneca (schizophrenia and Alzheimer's), TorreyPines (Sjogren's), Trophos (neuropathic pain). And many eyes will be tracking the fate of iloperidone/Fanapta's NDA, important to both Vanda Pharmaceuticals and Titan, as well as Zogenix's efforts to find a window for its IPO, for which the climate could hardly be worse.

Recent issues of NeuroInvestment have included our June review of the Multiple Sclerosis area, featuring information on advanced programs from BioMS, Biogen-Idec, Active Biotech, and Novartis. The next issue of NeuroInvestment will be our annual review of the Alzheimer's area, incorporating what has been learned from the full and partial failures of recent weeks and assessing the implications for the rest of the field.

NeuroInvestment is the independent, monthly review of the neurotherapeutics area. A one-year corporate subscription is $1600, email or hardcopy. Add $250 for dual delivery, add $50 for airmail delivery outside North America. A three month trial subscription is US$600. Individual investor information is available upon request.

NI Research is the leading publisher of independent research on the neuropharmaceutical/therapeutic industry. NI Research has published NeuroInvestment since 1995, the Private CNS Company Review since 2003, and CNS Disorders/Therapeutics since 2007. NI Research also provides inlicensing consultation and custom research for large and small pharmaceutical firms. NI Research has developed an unmatched information base regarding both publicly and privately-held neuro-oriented companies.

Contact: NI Research P.O. Box 1028 Cardiff CA 92007 760.230.2581 Email Contact Websites: www.niresearch.com www.neuroinvestment.com