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Share Name | Share Symbol | Market | Type | Share ISIN | Share Description |
---|---|---|---|---|---|
Circio Holding Asa | LSE:0RIS | London | Ordinary Share | NO0013033795 | CIRCIO HOLDING ORD SHS |
Price Change | % Change | Share Price | Bid Price | Offer Price | High Price | Low Price | Open Price | Shares Traded | Last Trade | |
---|---|---|---|---|---|---|---|---|---|---|
0.00 | 0.00% | 15.98 | 0.00 | 01:00:00 |
Industry Sector | Turnover | Profit | EPS - Basic | PE Ratio | Market Cap |
---|---|---|---|---|---|
Home Health Care Services | 10M | -432.9M | -2.2969 | -6.96 | 3.01B |
OSLO, Norway, Nov. 1, 2018 /PRNewswire/ --
Targovax ASA (OSE: TRVX), a clinical stage biotechnology company developing immune activators to target hard-to-treat solid tumors, today announces its third quarter 2018 results.
Targovax's management will host an online presentation for investors, analysts and the press at 08:45 CET. The presentation in Norwegian can be followed here, or at: https://www.facebook.com/AXExposure/videos/279295392691286/
An English version can be found on Targovax Events & Presentations from 08:45.
For a more elaborate presentation of Targovax, please visit targovax.com for a replay of the 15 October 2018 Capital Markets Day.
HIGHLIGHTS FOR THE THIRD QUARTER 2018
POST-PERIOD HIGHLIGHTS
Øystein Soug, CEO commented: "Targovax has made great progress in 2018. We have four ongoing clinical trials with our lead clinical product, ONCOS-102, and we reported interim response rate and immune activation data from the trials in mesothelioma and checkpoint inhibitor refractory melanoma. In particular, it was encouraging to see a complete response so early in the melanoma trial, which makes us confident that ONCOS-102 has the potential to provide an important future benefit for difficult-to-treat CPI refractory patients. We are now planning to expand the dosing to fully unlock that potential.
The results from the TG01 trial in resected pancreatic cancer have now also been fully analyzed. We see a very encouraging signal of efficacy, compared to historical control, both in terms of disease-free survival and overall survival. Whilst the ONCOS oncolytic virus program will remain our priority, we plan to continue and expand the TG development program. Based on the TG01 data, several academic groups have expressed interest in sponsoring pancreatic cancer combination trials with the TG vaccine. In addition, we will seek to combine TG vaccination with a checkpoint inhibitor in a small proof-of-concept trial."
Reporting material
Targovax third quarter 2018 report
Targovax third quarter 2018 presentation
The quarterly report and presentation are also available at the website www.targovax.com.
For further information, please contact:
Renate Birkeli, Investor Relations
Phone: +47-922-61-624
Email: renate.birkeli@targovax.com
Media and IR enquires:
Andreas Tinglum - Corporate Communications (Norway)
Phone: +47-9300-1773
Email: andreas.tinglum@corpcom.no
Simon Conway/Stephanie Cuthbert - FTI Consulting (International)
Phone: +44-20-3727-1000
Email: Targovax@fticonsulting.com
About Targovax
Activating the patient's immune system to fight cancer
Targovax (OSE:TRVX) is a clinical stage biotechnology company developing immune activators to target hard-to-treat solid tumors. Immuno-oncology is currently one of the fastest growing therapeutic fields in medicine.
Targovax's lead product candidate, ONCOS-102, is a genetically modified oncolytic adenovirus, which has been engineered to selectively infect and replicate in cancer cells. It has been shown to activate the immune system to generate tumor-specific immune responses. In phase I trials, ONCOS-102 induced both local and systemic innate and adaptive immune activation, which has been associated with clinical benefit. ONCOS-102's lead indication is mesothelioma, where the virus is currently being tested in a randomized phase II trial, with a phase Ib safety lead-in cohort. Another trial, in advanced melanoma, is expected to produce important proof of concept data for checkpoint inhibitor refractory patients.
Targovax is also developing a neo-antigen cancer vaccine targeting tumors that express mutated forms of RAS - mutations known to drive cancer. The TG vaccine program has shown a signal of efficacy compared to historical control in a 32-patient trial with TG01 in resected pancreatic cancer. A next generation product candidate, TG02 is currently tested as monotherapy and will also be tested in combination with KEYTRUDA® (an anti-PD1 check point inhibitor, CPI).
This information was brought to you by Cision http://news.cision.com
http://news.cision.com/targovax/r/targovax-asa--third-quarter-2018-results,c2661643
The following files are available for download:
Q3 report - http://mb.cision.com/Public/17093/2661643/85f997ca69858bc3.pdf
Presentation - http://mb.cision.com/Public/17093/2661643/85bb7888f3ba0149.pdf
View original content:http://www.prnewswire.com/news-releases/targovax-asa-third-quarter-2018-results-300742017.html
SOURCE Targovax
Copyright 2018 PR Newswire
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