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SDI Sdi Group Plc

62.50
0.00 (0.00%)
Last Updated: 08:00:00
Delayed by 15 minutes
Share Name Share Symbol Market Type Share ISIN Share Description
Sdi Group Plc LSE:SDI London Ordinary Share GB00B3FBWW43 ORD 1P
  Price Change % Change Share Price Bid Price Offer Price High Price Low Price Open Price Shares Traded Last Trade
  0.00 0.00% 62.50 62.00 63.00 62.50 62.50 62.50 79,395 08:00:00
Industry Sector Turnover Profit EPS - Basic PE Ratio Market Cap
Coml Physical, Biologcl Resh 67.58M 3.87M 0.0372 16.80 65.03M
Sdi Group Plc is listed in the Coml Physical, Biologcl Resh sector of the London Stock Exchange with ticker SDI. The last closing price for Sdi was 62.50p. Over the last year, Sdi shares have traded in a share price range of 59.50p to 179.50p.

Sdi currently has 104,050,044 shares in issue. The market capitalisation of Sdi is £65.03 million. Sdi has a price to earnings ratio (PE ratio) of 16.80.

Sdi Share Discussion Threads

Showing 1376 to 1396 of 4050 messages
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DateSubjectAuthorDiscuss
06/12/2018
00:58
The reason for the fall ?

I think it is this .... talk of a placing has shafted the share price .... very, very, silly as many have now sold thinking a placing is coming soon





hastings25 Sep '18 - 16:40 - 1297 of 1359

On my arrival, it was good to meet two other private investors who had travelled to the AGM where we were soon joined by the SDI people who had just concluded a board meeting.



No doubt the various pre-nuptials were played out before a tying of the knot, where now complete, there would certainly appear to be potential in terms of synergies going forward as it does indeed look another good fit.



With the banking facility in place (which could be upped if they chose) and positive cash on the balance sheet they can do two or three more similar purchases with this mix, although further ahead they wouldn't rule out a placing to support something larger.

buywell3
03/12/2018
18:48
Those here with contacts to SDI might like to pass this one on

Chronic Wasting Disease A Time Bomb For Agriculture?

JANUARY 29, 2018

In the USA prion proteins have been discovered on plant leaves and shoots , and roots.

ProReveal can detect prion proteins

The spread of prions to plants/grasses and hence cereal crops is directly linked to the CWD epidemic now raging across the USA within the deer/Elk and Moose populations




My point is this,

What country wants to import cereal crops from the USA or any other crops for that matter that have been grown in CWD ( prion) infected soil ?

Hence could ProReveal also have the potential to be used for prion presence on food crops ?

''It is incumbent on the agriculture industry to consider the ramifications of CWD spread through agricultural commodities, according to Clausen. “Sometimes we just seem to bounce from crisis to crisis without enough preparation or foresight. Corn or alfalfa, CWD uptake has been demonstrated in plants. Whether the uptake is infectious, that research hasn’t been done.”

buywell3
03/12/2018
17:25
This new ProReveal 'white paper' is a very good idea to drive sales in the USA ... well done SDI , several USA hospitals now have ProReveal installed.

If I was a USA citizen this would cause me some concern

'' in the past three years alone, 31 patients in North Carolina and New Hampshire and an undisclosed number of patients traced over a three-month period at Washington Regional Medical Center have been put at risk of contracting vCJD via being operated on with contaminated surgical instruments".



In 2015 there was another vCJD case in the USA


another in 2014


Creutzfeldt-Jakob disease (CJD) is a rare, degenerative, fatal brain disorder. It affects about one person in every one million per year worldwide; in the United States there are about 350 cases per year.


CJD belongs to a family of human and animal diseases known as the transmissible spongiform encephalopathies (TSEs) or prion diseases. A prion—derived from “protein” and “infectious”—causes CJD in people and TSEs in animals.

In some cases, CJD has spread to other people from grafts of dura mater (a tissue that covers the brain), transplanted corneas, implantation of inadequately sterilized electrodes in the brain, and injections of contaminated pituitary growth hormone derived from human pituitary glands taken from cadavers.

It is also worth noting there has been several incidences of BSE in the USA

There have been 6 cases of BSE identified in the United States. The following information provides descriptions of these 6 cases:

2018- Florida
2017 – Alabama
2012 - California
2006 - Alabama
2005 - Texas
2003 - Washington State

So the potentail for CJD and vCJD has never gone away





In a couple of posts on here in the past I have referred to the risk that UK citizens pose to the USA as more than 1 in 2000 are CJD or vCJD carriers which type is not known also there has since been yet another type CJD protein identified which is more common , so 1 in 2000 carriers is probably wrong ... it could be 1 in 1000 nobody knows because the original study just looked at peoples appendixes removed after surgery. Nothing like it has been done since and that does NOT give the whole picture.

So now blood has also been looked at as a source of CJD transmission in the states

UK citizens get a mention



Based on these results, FDA is proposing to recommend deferral only for donors who spent time in U.K., Ireland,and France (and donors exposed to U.K. beef on certain U.S. military bases in Europe.



My point previously was that people from the UK living in the USA because many of them are CJD carriers pose a risk to the rest of the USA population

The FDA in 2017 in the link above are waking up to this fact


The FDA state re blood donors


A. Recommendations for Donor Deferral

We recommend that you defer donors for geographic risk of BSE exposure as follows:
1. Defer indefinitely a donor who has spent three months or more cumulatively in
the U.K. from 1980 to 1996.

2. Defer indefinitely a donor who has spent five years or more cumulatively in
France or Ireland2 from 1980 to 2001.

3. Defer indefinitely former or current U.S. military personnel, civilian military
personnel, and their dependents as follows:

a. Individuals who resided at U.S. military bases in Northern Europe (Germany,
U.K., Belgium, and the Netherlands) for six months or more from 1980
through 1990, or

b. Individuals who resided at U.S. military bases elsewhere in Europe (Greece,
Turkey, Spain, Portugal, and Italy) for six months or more from 1980 through
1996.

4. Defer indefinitely a donor with a history of blood transfusion in the U.K., France,or Ireland from 1980 to the present.





What will the FDA come up with next with recommendations about prion testing ... which is what they should be looking at now ?

buywell3
03/12/2018
11:43
New product news:



"Syngene introduces next generation G:BOX imaging systems
November 20th, 2018

Cambridge, UK: Syngene, a world-leading manufacturer of image analysis solutions, is delighted to announce its new generation G:BOX Chemi XX6/XX9 multi-application imaging systems are now available. Featuring the latest, ultra-sensitive, fast capture lens, these systems ensure scientists can have total confidence that their gel and blot results are accurate and publication-ready.

Utilising a state-of-the-art wide aperture f0.8 lens, the camera in the next generation G:BOX Chemi XX6/XX9 systems can capture more light, which means scientists can use shorter excitation times when imaging IR and R,G,B fluorescence blots and gels, thus reducing photobleaching and generating more accurate results. The high-performance lens also speeds up chemiluminescent imaging and lowers reagent costs by reducing the amount of expensive antibodies needed to visualise bands.....

.....“The feedback we have had from talking to scientists worldwide is that they want easy to use equipment which has fast IR fluorescence and chemi image capture times, yet produces true to life images,” says Dr Martin Biggs, Sales Manager at Syngene “We’ve responded by integrating one of the world’s best in class lens into our G:BOX XX6/XX9 systems and now, without having to become an imaging expert, any researcher using this technology will get great imaging performance with results they can trust.”

rivaldo
03/12/2018
08:22
Interim results out in a few weeks and perhaps we can emulate JDG with its recent TU.
hastings
23/11/2018
13:00
Yes it's surprising rivaldo nervous times I suppose but also of course it's giving a good top up opportunity :-)
cheshire man
23/11/2018
11:58
It's ironic that SDI's share price has fallen just as sector comparator JDG jumps after reporting on Wednesday that trading is ahead of expectations.

There should be some encouragement from a fellow scientific instrument group reporting such strong trading.

rivaldo
23/11/2018
11:54
pugugly if so it has allowed buyers to top up or newbies get in at a very good sp,,,,,took advantage myself yesterday having had a top up and looking forward to results in a few weeks :-)
cheshire man
23/11/2018
10:57
Looks like an iceberg dump going on in the backround - Any thoughts as to who might be unloading and how much more they have to go - All apparently buys accouring to the ADVFN attribution but and slight fall since open of the offer price
pugugly
23/11/2018
08:59
Nice synopsis pireric. with which i fully concur. SDI happens to be my current largest pf holding.
cfro
22/11/2018
19:47
I have significantly added to my position here. Updated thesis below. Think results next month will put investors back on the right path
pireric
21/11/2018
18:48
Not sure about vegan yet, but vegetarianism is definitely better for both health sand environment. And in both squirrel and metaphorical terms, a No Brainer!
brucie5
18/11/2018
16:22
As far as SDI is concerned a no deal isn't a big deal.
hastings
18/11/2018
15:29
quite cheap
solooiler
18/11/2018
15:12
Hastings - Quite probably as similar charts applicable to many shares BUT with incresed volatility and factors such as TRUMP, BREXIT, ITALIAN BUDGET, MBS, The Israeli foul up in Gaza - with possible forced elections - etc etc - the Investing world is becoming more dangerous - Maybe we should follow the old Jim Slater Advice and add some AK-47's to our private portfolio's !!!
pugugly
18/11/2018
15:04
Nothing more than market malaise, so if there is any further downward movement then it merely strengthens the buying opportunity.
hastings
18/11/2018
14:52
Chart is starting to look a bit worrying - Since August we have had lower lows and lower highs - If 36p does not hold then a technical worry - (imo_)
pugugly
18/11/2018
09:52
I liked that you used "nuts" and "squirrels" in the same context
getscenic
18/11/2018
02:08
I very nearly posted this last year about squirrels and prion disease ,,, but desisted

Times have now changed as people now realize prion disease is the new killer by brain fade ..Alzheimer's ... dementia , Parkinson's etc that is slowly eating us up


Kentucky Doctors Warn Against a Regional Dish: Squirrels' Brains
By SANDRA BLAKESLEEAUG. 29, 1997


Doctors in Kentucky have issued a warning that people should not eat squirrel brains, a regional delicacy, because squirrels may carry a variant of mad cow disease that can be transmitted to humans and is fatal.

Although no squirrels have been tested for mad squirrel disease, there is reason to believe that they could be infected, said Dr. Joseph Berger, chairman of the neurology department at the University of Kentucky in Lexington. Elk, deer, mink, rodents and other wild animals are known to develop variants of mad cow disease that collectively are called transmissible spongiform encephalopathies.

In the last four years, 11 cases of a human form of transmissible spongiform encephalopathy, called Creutzfeldt-Jakob disease, have been diagnosed in rural western Kentucky, said Dr. Erick Weisman, clinical director of the Neurobehavioral Institute in Hartford, Ky., where the patients were treated.

''All of them were squirrel-brain eaters,'' Dr. Weisman said. Of the 11 patients, at least 6 have died.

Within the small population of western Kentucky, the natural incidence of this disease should be one person getting it every 10 years or so, Dr. Weisman said. The appearance of this rare brain disease in so many people in just four years has taken scientists by surprise.

While the patients could have contracted the disease from eating beef and not squirrels, there has not been a single confirmed case of mad cow disease in the United States, Dr. Weisman said. Since every one of the 11 people with the disease ate squirrel brains, it seems prudent for people to avoid this practice until more is known, he said.

The warning, describing the first five cases of Creutzfeldt-Jakob disease, will appear in tomorrow's issue of The Lancet, a British medical publication.

The disease in humans, squirrels and cows produces holes in brain tissue. Human victims become demented, stagger and typically die in one or two years. The people who died from Creutzfeldt-Jakob disease in Kentucky were 56 to 78, lived in different towns and were not related, Dr. Weisman said.

The cause of transmissible spongiform encephalopathies is hotly debated. Many scientists believe that the infectious agent is a renegade protein, called a prion, which can infect cells and make copies of itself. Others argue that a more conventional infectious particle causes these diseases but that it has not yet been identified. In either case, the disease can be transmitted from one animal to another by the eating of infected brain tissue.

Such diseases were considered exotic and rare until 10 years ago, when an outbreak occurred among British cattle. Tens of thousands of animals contracted a bovine variant called mad cow disease, and their meat along with bits of brain tissue was sold as hamburger. Thus far 15 people in Britain have died of a transmissible spongiform encephalopathy that they seemed to have contracted from eating infected meat.

Most people with Creutzfeldt-Jakob disease are elderly, but the British victims were all young, which alarmed public health officials. The outbreak in western Kentucky has occurred in older people, Dr. Weisman said, ''which makes me think there may have been an epidemic 30 years ago in the squirrel population.'' Transmissible spongiform encephalopathies have a long latency period, he said, which means many people in the South may be at risk and not know it.

Squirrels are a popular food in rural Kentucky, where people eat either the meat or the brains but generally not both, Dr. Weisman said. Families tend to prefer one or the other depending on tradition. Those who eat only squirrel meat chop up the carcass and prepare it with vegetables in a stew called burgoo. Squirrels recently killed on the road are often thrown into the pot.

Families that eat brains follow only certain rituals. ''Someone comes by the house with just the head of a squirrel,'' Dr. Weisman said, ''and gives it to the matriarch of the family. She shaves the fur off the top of the head and fries the head whole. The skull is cracked open at the dinner table and the brains are sucked out.'' It is a gift-giving ritual. The second most popular way to prepare squirrel brains is to scramble them in white gravy, he said, or to scramble them with eggs. In each case, the walnut-sized skull is cracked open and the brains are scooped out for cooking.

These practices are not a matter of poverty, Dr. Berger said. People of all income levels eat squirrel brains in rural Kentucky and in other parts of the South. Dr. Frank Bastian, a neuropathologist at the University of South Alabama in Mobile, said he knew of similar cases of Creutzfeldt-Jakob disease in Alabama, Mississippi and West Virginia.

Squirrel hunting season began last week, and it lasts through early December, Dr. Berger said. He and Dr. Weisman are asking hunters to send in squirrel brains for testing, including those taken from dead animals found on the roadside. A mad squirrel would be more likely to stagger into the road and be struck by vehicles, Dr. Berger said.

buywell3
18/11/2018
01:40
Readers of my posts here might think I'm nuts re my prion disease and ProReveal posts

Which brings me to the USA and human consumption of squirrel brains ... something I was going to post on ... but buried it for later use

So we have

Prion expert: ‘A link between consumption of squirrel brain and human prion disease is unjustifiably speculative’

October 22, 2018

In a follow-up to a report of a poster presented at IDWeek2018 concerning a relatively recent case of vCJD linked to the consumption of squirrel brains, an expert from National Prion Disease Pathology Surveillance Center at Case Western Reserve University School of Medicine said the link was “unjustifiably speculative”.


“This diagnosis was based on MRI results that reportedly appeared similar to those of patients with variant CJD (vCJD). However, all other clinical and demographic evidence (triphasic EEG pattern, patient age, disease duration, and, subsequently, prion protein codon 129 genotype) strongly suggested that this was a case of sporadic Creutzfeldt-Jakob disease (sCJD). Indeed, through national human prion disease surveillance, the patient was confirmed through autopsy as sCJD, not vCJD. The reporting of this case as probable vCJD — a disease linked to consumption of beef contaminated with bovine spongiform encephalopathy (BSE, also known as “mad cow disease”) — and suggesting that this case might be etiologically linked to squirrel consumption is inappropriate and may cause undue alarm.

“While prion diseases have been identified in several other types of mammals, they have never been identified in squirrels. Without additional experimental or epidemiological evidence, a link between consumption of squirrel brain and human prion disease is unjustifiably speculative.”

buywell3
17/11/2018
23:32
The NHS is Scotland and England need to wake up and smell the coffee

What the University Hospital Wales have achieved here is ....... BIG ........

By using ProReveal in just six months, that Hospital has been able to reduce residual proteins from 3µg to 400ng


This means in percentage terms the University Hospital Wales have reduced in-situ residual protein levels ie the protein residue 'left overs' on the cleaned/washed surgical instrument that is now ready to be used on the next patient

By a staggering 86.7%


This is because 1µg = 1000 ng


To say this again in another way

By utilizing ProReveal , Mark Campbell, Decontamination Service Manager to the University Hospital Wales has reduced the potential risk of passing prion disease (vJCD ) and others by the use of contaminated surgical instruments

By a factor of ....................... 87%


This information should be emailed and disseminated across the whole of the NHS in the united kingdom

IT IS A NO BRAINER

The new NHS Health Minister should be shown this













University Hospital Wales uses ProReveal in-situ protein detection test
2/11/2018

Synoptics Health, a part of the Scientific Digital Imaging Group of companies and a manufacturer of innovative digital imaging systems for healthcare applications, is delighted to announce that ProReveal, its sensitive test to detect proteins on surgical instruments, is now in use at the University Hospital of Wales (UHW).
ProReveal is being used at UHW for routine monitoring and process improvement of surgical instrument decontamination protocols to help prevent inadvertent exposure to prion infections associated with conditions such as vCJD (Creutzfeldt Jakob Disease).

The HSDU Department at UHW is using ProReveal in-situ fluorescence detection daily to precisely quantify how much protein remains on reprocessed surgical instruments and is the first in Wales to adopt the technology.

Additionally, ProReveal is being used as part of continuous process improvement research where staff are assessing a range of decontamination parameters such as manual pre-washing and ultrasonic cleaning, as well as different types of washer/disinfectors and detergents to develop the optimum process for removing residual protein on neurosurgical instruments.

Mark Campbell, Decontamination Service Manager at UHW said: “The HTM 01-01 is quite clear that instruments used in neurosurgery should be tested for proteins using in-situ methods rather than swabs because potentially they aren’t sensitive enough to detect low levels of proteins or indeed prion proteins. We have been trialling ProReveal since 2016 and decided that as this is currently the only in-situ test, we purchased a system in 2017 to ensure compliance to the updated WHTM and bring further safety factors for managing high risk sets.”

Mark added: “We now use ProReveal for routine testing and as a research improvement tool to help us reduce the amount of residual protein on neurosurgical instruments. By reviewing and making changes to our decontamination process, in just six months, we have been able to reduce our residual proteins from 3µg to 400ng and have set our ProReveal to detect nanogram rather than microgram levels as we were getting results of 0µg. The ProReveal is now key to assuring us that we have done everything practically possible to reduce patients’ risk of exposure to prion related diseases.”

Guy Fiddian, of Synoptics Health’s commented: “We’re pleased that the largest hospital in Wales is also the first to be routinely using ProReveal for in-situ detection of proteins on reprocessed surgical instruments. Their rigorous approach to continuous quality improvement has shown some very impressive results in reducing residual proteins on neurosurgical instruments and demonstrates that minimizing patients’ exposure to prions is viewed very seriously by this hospital.”

buywell3
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