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Share Name Share Symbol Market Type Share ISIN Share Description
Open Orphan Plc LSE:ORPH London Ordinary Share GB00B9275X97 ORD 0.1P
  Price Change % Change Share Price Bid Price Offer Price High Price Low Price Open Price Shares Traded Last Trade
  -0.05 -0.17% 28.75 28.50 29.00 29.25 28.25 29.25 2,584,614 15:36:51
Industry Sector Turnover (m) Profit (m) EPS - Basic PE Ratio Market Cap (m)
Health Care Equipment & Services 3.3 -5.6 -3.4 - 192

Open Orphan Share Discussion Threads

Showing 10076 to 10097 of 14125 messages
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DateSubjectAuthorDiscuss
01/12/2020
11:40
M5 Have you had a look at ERGO yet..what do you think.Just broken out to a good upward trend in tandem with ORPH.
bramble13
01/12/2020
10:35
Seems to have stagnated recently - probably healthy after the great rises since c took over. The thing is as i see it, we are pregnant with news on several fronts, and they all seem like mega news to me, which will instantly drive orph beyond the recent 32p high (still be massively undervalued there imo). If nothing happens, this is worst case, then as time passes, the challenge study business will gradually plod on raking in the tens of millions (40/50m already signed iirc) and for the most conservative investors, the next results will show the profitability of this core business. So with no more news at all, the future share price will rise a lot as the cor business does its stuff - it's all signed, fully booked, for 18m. That alone is pretty unbelievable. The developments on top of that core are transformative, i.e. big enough to completely revalue orph. An announcement on the wearables (the world's richest men approached orph about their data), or an announcement on the imutexplus float/sale will have an instant major price effect. Another less discussed positive price angle is an rns saying an inst has passed 3% on their own book. I would really rate that as a major price driver over the coming year. If/when c gets the use of another suitable clinic, then for 24 beds, i think you can add another 30m profit to the bottom line. It would instantly be filled with challenge studies - the only problem with the demand is satisfying it. M, agree - orph is hard to give your real views on because it all sounds so ramplike!. But if posts act as a catalyst for others to look into the 'ramps' then it's worth it.
pierre oreilly
01/12/2020
10:24
Dr Chiu - Ethical Approval for Covid CHIMs ‘Ethical approval is a multi-stage process, and we are just about to get approval to start the screening,” said Dr Chiu. ‘I hope that we will be able to start recruiting (volunteers) around late November.’R30;. … Dr Chiu. ‘We hope to present our findings to the ethics committee around the time we start screening, and we will be publishing the protocol and the public engagement findings as well.” hxxps://www.sciencemuseumgroup.org.uk/blog/coronavirus-should-we-infect-young-people-with-covid-19/?utm_source=Twitter&utm_medium=Organic%20Link&utm_campaign=L%20AP:%20Science%20Museum%20Group%20Blog%2018/11/20 Based on the above, Dr Chiu should have presented his evidence to the Ethics Committee by now, so presumably we are due a regulatory decision from this week onwards?
trader_3
01/12/2020
09:53
Nice to hear. Yes looks nicely set up here so will be adding when I can. Must catch up properly sometime.
rafboy
01/12/2020
09:39
Hi M5 keeping well here and trust you are good too. Watching AGL but FDA is some months away yet.
rafboy
01/12/2020
09:36
Good to see you here!! I hope you are well. You still in AGL? Watching that one carefully as due a reversal, just keeping an eye on the chart for a signal. Good luck.
m5
01/12/2020
09:12
Taken a position here over the last week or so. Must admit it does look likely to breakout soon.
rafboy
01/12/2020
09:07
Agreed....watch the presentations, see where Orphan are going and you just know. Just a question of when now and a killer RNS to light the touchpaper.
molatovkid
01/12/2020
08:55
We had the same at 16p and then went on to double.
sh0wmethemoney
01/12/2020
08:52
I am with u there m5,like a coiled spring ready to pop IMO.
sh0wmethemoney
01/12/2020
08:49
Call its ramping if you like, but my bones are telling me that when this pops its going to pop in a big way. I have seen these consolidation patterns many times before and I would say that when a share is in a firm uptrend, as we have here, the tighter the consolidation the bigger the move. Lets see what happens. I am going to stick my neck out and say we will see 40p minimum by Xmas. DYOR, NOT ADVICE, MY PERSONAL OPINION.
m5
01/12/2020
08:32
Tick up from the 24.5 - 25.5p soon by the look of it.
sh0wmethemoney
30/11/2020
20:31
Good find Trader, I think it’s pretty clear now that the regulators are going to certify the COVID CHIMs but it’s just a question of when. Hopefully it will be soon because I feel that might be the catalyst that sets the Orph share price on the next leg up.
warranty
30/11/2020
19:07
Exploring Risks of Human Challenge Trials for COVID-19 ‘In this paper, the researchers present an interactive model for exploring some of the risks of a SARS-COV-2 dosing study, which is a prerequisite for COVID-19 human challenge trials…. ….since this infection fatality rate will be further reduced in an actual HCT through screening for comorbidities and providing aggressive treatment for any cases that do occur, the team projects the actual risk to be only around 3.1 per 100,000, with a 99.85% probability of no fatalities and a 98.7% chance of no one getting hospitalized…. …According to the authors, it is likely that HCTs are a viable method of rapidly testing vaccine efficacy, which is even more critical during a raging pandemic.’ “It seems likely that Challenge trials are a viable way to rapidly test vaccine efficacy, which is particularly critical now for testing second-generation vaccines, which may prove superior to first generation vaccines, or at least help fill the demand unmet by first-generation candidates.” hxxps://www.news-medical.net/news/20201130/What-are-the-risks-associated-with-human-challenge-trials-for-SARS-CoV-2-vaccine-candidates.aspx hxxps://www.medrxiv.org/content/10.1101/2020.11.19.20234658v1.full.pdf Similar to the recent liability insurance cover (announced by the UK Gov business secretary), this is another important prerequisite positive ‘tick in the box’, for the Covid CHIM implementation.
trader_3
30/11/2020
14:35
Afternoon all. Interesting reversal potentially coming into play. As always intra noise until its confirmed at the close, but there has definitely been a pattern. For the past 5 weeks we have seen the same, its plain to see when looking at the weekly chart, where one candle gives you the weeks trading overview. Huge support area. 20 Minutes to go, down a penny to evens. News anybody?
m5
30/11/2020
11:07
UK Gov - Medicines and Diagnostic Manufacturing Transformation Fund Prime Minister Boris Johnson said: “This new £20m fund will significantly increase the capacity and resilience of our medicines and diagnostics manufacturing supply chains and equip us to fight future health crises. Throughout the pandemic we have seen a coming together of British scientific industry and innovation and this new fund will enhance the UK’s manufacturing capabilities even further.” Business Secretary Alok Sharma said: “The positive and timely response of our medicines manufacturers to the pandemic has been remarkable, but we want to ensure that the UK’s supply chains are even more resilient in the future. “There are huge opportunities for innovation in medicines and diagnostics, and this new fund will put the UK head and shoulders above others, boosting the UK’s capabilities and generating significant economic opportunities across the country.” The pandemic has shown the importance of having a strong domestic medicines and diagnostics manufacturing industry. This new fund has been established to grow and strengthen the UK’s capabilities, by encouraging companies to develop new technologies, build new factories and harness new advances, including bioprocessing, data and using greener manufacturing processes.” https://www.gov.uk/government/news/prime-minister-announces-20m-to-grow-medicines-manufacturing-in-the-uk Not specifically related to vaccine testing but signals a great future for UK companies like ORPH.
trader_3
30/11/2020
10:21
Well if one assumes our CEOs view on a decade long shift to use of our labs etc. Then that’s a lot of new data each year going forward. So hopefully a recurring revenue deal.
uapatel
30/11/2020
10:18
I assume we sell access to the database, which is being constantly updated as more data is gathered, wearables manufacturer writes the algorithm that works out what the wearer's health problem is based on the data. As to how we are selling I have no idea exclusive or be a provider to the market, depends on what method gives the best profit or what buyers will pay for, only person that knows that is CF I suggest.
pogue
30/11/2020
10:00
I would have thought that the wearables use the data bases, ORPH etc, to test for certain conditions on the wearer to trigger an alert. I dont really know ,interesting though
malcolmmm
30/11/2020
09:44
On the hvivo wearables data side of things....would any deal with a phone provider be exclusive or non-exclusive ?? I'd like to think non-exclusive obviously...
molatovkid
30/11/2020
09:34
EU Tender - Future Infectious Disease Threats to Europe: A Foresight Approach Cathal has previously described the future of ORPH linked to “entering a decade of exponential vaccine development". If any further proof was needed, below is a European Union tender for Future Infectious Disease Threats to Europe, stating: ‘The goal of this tender is to: ‘Identify the threat spectrum from emerging infectious diseases (EID) in Europe over the next 3 to 8 years’….. ….and drive vaccine development that can be used for infectious disease control and countermeasures.’ https://etendering.ted.europa.eu/document/document-old-versions.html?docId=80972 As ORPH is the world’s leading company in vaccine and anti viral testing, the short to long term future, looks extremely secure. IMHO
trader_3
29/11/2020
19:52
Trader_3 very good video as you say Dr Catchpole comes across very professional. Thanks
666james
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