Mereo BioPharma Group plc Director/PDMR Shareholding (5582L)

TIDMMPH

RNS Number : 5582L

Mereo BioPharma Group plc

27 December 2018

Mereo BioPharma Group plc

("Mereo" or the "Company")

Notification of PCA Dealing

London, 27 December 2018 - Mereo BioPharma Group plc (AIM: MPH), a clinical stage UK based biopharmaceutical company focused on rare diseases, received notification that on 21 December 2018, Eric Scots-Knight, a person closely associated (PCA) with Denise Scots-Knight, Chief Executive Officer of Mereo, purchased ordinary shares of GBP0.003 each in the Company, as set out in the following table.

The below announcement and notification is made in accordance with the EU Market Abuse Regulation. The form required under the EU Market Abuse Regulation follows.

DEALING NOTIFICATION FORM

FOR USE BY PERSONS DISCHARGING MANAGERIAL RESPONSIBILITY AND THEIR CLOSELY ASSOCIATED PERSONS

 
 1    Details of the person discharging managerial responsibilities 
       / person closely associated 
 a)   Name                      Eric Scots-Knight 
     ------------------------  --------------------------------------------- 
 2    Reason for the notification 
     ----------------------------------------------------------------------- 
 a)   Position/status           PCA of Denise Scots-Knight, Chief Executive 
                                 Officer 
     ------------------------  --------------------------------------------- 
 b)   Initial notification      Initial Notification 
       / Amendment 
     ------------------------  --------------------------------------------- 
 3    Details of the issuer, emission allowance market participant, 
       auction platform, auctioneer or auction monitor 
     ----------------------------------------------------------------------- 
 a)   Name                      Mereo BioPharma Group plc 
     ------------------------  --------------------------------------------- 
 b)   LEI                       213800U8JQHIJOS5AS09 
     ------------------------  --------------------------------------------- 
 4    Details of the transaction(s): section to be repeated for 
       (i) each type of instrument; (ii) each type of transaction; 
       (iii) each date; and (iv) each place where transactions 
       have been conducted 
     ----------------------------------------------------------------------- 
 a)   Description of            Ordinary Shares of GBP0.003 each 
       the financial 
       instrument, type          ISIN: GB00BZ4G2K23 
       of instrument 
       Identification 
       code: 
     ------------------------  --------------------------------------------- 
 b)   Nature of the             Purchase of shares 
       transaction 
     ------------------------  --------------------------------------------- 
 c)   Price(s) and               185 pence. 3000 Ordinary Shares of GBP0.003 
       volume(s)                  each 
     ------------------------  --------------------------------------------- 
 d)   Aggregated information    185 pence. 3000 Ordinary Shares of GBP0.003 
                                 each. 
     ------------------------  --------------------------------------------- 
 e)   Date of the transaction   21 December 2018 
     ------------------------  --------------------------------------------- 
 f)   Place of the              London Stock Exchange 
       transaction 
     ------------------------  --------------------------------------------- 
 

Enquiries:

 
Mereo BioPharma Group plc                    [phone] 
Denise Scots-Knight, Chief Executive 
 Officer 
Richard Jones, Chief Financial Officer 
 
Cantor Fitzgerald Europe (Nominated 
 Adviser and Broker)                         [phone] 
Phil Davies 
Will Goode 
Rick Thompson 
 
RBC Capital Markets (Joint Broker)           [phone] 
Rupert Walford 
Jamil Miah 
 
FTI Consulting (Public Relations Adviser)    [phone] 
Simon Conway 
Brett Pollard 
 
Burns McClellan (US Public Relations 
 Advisor to Mereo Biopharma)                +01 (0) 212 213 0006 
Lisa Burns 
Ami Bavishi 
 

About Mereo

Mereo is a biopharmaceutical company focused on the development and commercialization of innovative therapeutics that aim to improve outcomes for patients with rare diseases. Mereo's strategy is to selectively acquire product candidates that have already received significant investment from pharmaceutical companies and that have substantial preclinical, clinical and manufacturing data packages. In December 2018, Mereo announced the proposed combination of Mereo and OncoMed Pharmaceuticals, with the transaction expected to close in the first half of 2019. Each of Mereo's four product candidates has previously generated positive clinical data for Mereo's target indication or in a related indication. Since inception Mereo has commenced large, randomized, placebo-controlled Phase 2 clinical trials for all four of the product candidates:

-- BPS-804 for osteogenesis imperfecta (OI). The Company recently announced completion of enrolment with 112 adult patients in a Phase 2b dose ranging study with some initial data expected in the H1 2019 and top-line dose ranging data in late 2019. A pediatric Phase 3 study design has also been approved by the EMA. BPS-804 has orphan designation in the US and EU and has been accepted into the PRIME and Adaptive Pathways in EU;

-- MPH-966 for alpha-1 antitrypsin deficiency (AATD). The Company recently announced first patient in in a Phase 2 dose ranging study in the US with data expected in late 2019;

-- BCT-197 for acute exacerbations of COPD (AECOPD). The Company announced positive top-line Phase 2 data in December 2017; and

-- BGS-649 for hypogonadotropic hypogonadism (HH). The Company announced positive top-line Phase 2b data in March 2018 and positive results in December 2018 from the safety extension to the Phase 2b clinical trial.

-- As at September 30, 2018 Mereo had (unaudited) total cash resources of approximately US$44.6 million

This information is provided by RNS, the news service of the London Stock Exchange. RNS is approved by the Financial Conduct Authority to act as a Primary Information Provider in the United Kingdom. Terms and conditions relating to the use and distribution of this information may apply. For further information, please contact [e-mail] or visit www.rns.com.

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December 27, 2018 05:02 ET (10:02 GMT)