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HEMO Hemogenyx Pharmaceuticals Plc

1.76
-0.0025 (-0.14%)
28 Mar 2024 - Closed
Delayed by 15 minutes
Share Name Share Symbol Market Type Share ISIN Share Description
Hemogenyx Pharmaceuticals Plc LSE:HEMO London Ordinary Share GB00BYX3WZ24 ORD GBP0.01
  Price Change % Change Share Price Bid Price Offer Price High Price Low Price Open Price Shares Traded Last Trade
  -0.0025 -0.14% 1.76 1.73 1.76 1.75 1.73 1.74 7,822,292 16:35:08
Industry Sector Turnover Profit EPS - Basic PE Ratio Market Cap
Finance Services 0 -3.98M -0.0035 -4.97 19.87M

Hemogenyx Pharmaceuticals PLC Final Results (6279M)

30/04/2018 4:23pm

UK Regulatory


Hemogenyx Pharmaceuticals (LSE:HEMO)
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From Mar 2019 to Mar 2024

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TIDMHEMO

RNS Number : 6279M

Hemogenyx Pharmaceuticals PLC

30 April 2018

Hemogenyx Pharmaceuticals Plc

("Hemogenyx" or the "Company")

Final Results for the year ended 31 December 2017

Hemogenyx Pharmaceuticals plc (LSE: HEMO), formerly named Silver Falcon plc ("Silver Falcon"), a business formed for the purpose of acquiring another business or asset, reports its Final Results for the year ended 31 December 2017. The business of the Company is now the development of therapies for the treatment of blood diseases.

All financial amounts are stated in GBP British pounds unless otherwise indicated.

Key highlights

   --     Successful acquisition of Hemogenyx Pharmaceuticals for GBP8m in shares in October 2017 
   --     Change of name to Hemogenyx Pharmaceuticals Plc 
   --     GBP2m raised in a Placing and Subscription 

-- LakePharma, Inc. appointed as service provider for development of, CDX bi-specific antibodies

   --     University of Oxford collaboration aims to accelerate development of blood cancer treatments 

-- Overall work is progressing successfully towards the goal of submitting an IND application to the FDA

Post-period end highlights

-- First data results show CDX antibodies can attack and eliminate Acute Myelogenous Leukemia in vitro

-- Patent application filed relating to new type of humanised mouse (with chimeric mouse-human blood system)

   --     Appointment of Sir Marc Feldmann, pioneer of anti-TNF therapy, as Executive Chairman 
   --     Appointment of cancer research expert Dr Michael Shepard to Scientific Advisory Board 
   --     Collaboration with major US biotechnology firm worth up to US$250,000 

Dr. Vladislav Sandler, CEO of Hemogenyx, said:

"2017 was a significant year for Hemogenyx as we successfully listed the business on the London Stock Exchange and raised the financing necessary to further develop novel therapies with the potential to transform the lives of bone marrow transplant patients. We remain on track in the development of both of our products according the timescale we outlined to investors in October. We continue to successfully develop our Hu-PHEC cell therapy product and we are on course to have our CDX antibodies product in readiness for the start of Phase 1 trials as planned."

 
 Hemogenyx Pharmaceuticals Limited                                            www.hemogenyx.com 
 Dr Vladislav Sandler, Chief Executive                                          Via Walbrook PR 
  Officer & Co-Founder 
 Sir Marc Feldmann, Chairman 
 
 Optiva Securities Ltd                                                 Tel: +44 (0)20 3137 1902 
 Christian Dennis 
 
 Shard Capital Partners LLP                                            Tel: +44 (0)20 7186 9950 
 Damon Heath, Erik Woolgar 
 
 Peterhouse Corporate Finance Limited                                  Tel: +44 (0)20 7469 0930 
 Lucy Williams/Duncan Vasey 
 
 Walbrook PR                               Tel: +44 (0)20 7933 8780 or hemogenyx@walbrookpr.com 
 Paul McManus                                                          Mob: +44 (0)7980 541 893 
 
 

About Hemogenyx Pharmaceuticals Plc

Hemogenyx Pharmaceuticals Plc is a publicly traded company (LSE: HEMO) headquartered in London, with its wholly owned U.S. operating subsidiary, HemoGenyx LLC, located in its state-of-the-art research facility in Brooklyn, New York. HemoGenyx is a preclinical-stage biopharmaceutical company focused on the discovery, development and commercialization of novel therapies and treatments for blood diseases such as leukemia and lymphoma. The company's leading technologies aim to change the way in which bone marrow/hematopoietic stem cell (BM/HSC) transplants are performed and improve their efficacy. HemoGenyx's two distinct and complementary products include an immunotherapy product for patient conditioning-the CDX bi-specific antibody-and a cell therapy product for BM/HSC transplantation-the HuPHEC. Each of these products holds the potential to revolutionize the way BM/HSC transplants are being performed, offering solutions that mitigate the dangers and limitations associated with the current standard of care. For more information, visit www.hemogenyx.com.

Chairman's Statement

I am very pleased to present an update on the Company for the year ended 31 December 2017. I took over as Chairman on April 9, 2018, succeeding Dr Robin Campbell.

Silver Falcon listed on the London Stock Exchange on 9 November 2015. Following the evaluation of a number of acquisition opportunities, it announced on 11 September 2017 an agreement to acquire the entire share capital of Hemogenyx Pharmaceuticals Limited for GBP8m (the "Acquisition"), to be satisfied by the issue of 228,571,428 Consideration Shares at a price of 3.5p per share. The acquisition constituted a reverse takeover under IFRS2.

Concurrent with the acquisition the Company raised GBP2m (before expenses) through the issue of 57,142,857 New Ordinary Shares in a Placing and Subscription at a price of 3.5p per share, as well as offering 1 new share for 2 warrants to qualifying shareholders over 62,021,429 New Ordinary Shares at 4.0p per share. Silver Falcon formally changed its name to Hemogenyx Pharmaceuticals Plc.

Hemogenyx Pharmaceuticals Limited is the holding company for Hemogenyx LLC ("Hemogenyx"), a US based biotechnology company developing therapies to transform bone marrow and blood stem cell transplant procedures. These therapies aim to replace the need for the imperfect existing methods of preparation of patients for transplantation, such as chemotherapy and radiation treatments, and at the same time address the problem of finding matching stem cell donors whilst reducing the risk of blood stem cell rejection after transplantation.

Consequently, shareholders now have exposure to an important and growing area of treatment for serious blood diseases, such as leukaemia and myeloma, whose treatment is currently restricted in use by risk of toxicity. The two products being developed by Hemogenyx have the potential to transform, and potentially revolutionise, the bone marrow or blood stem cell transplant procedure used to treat the most severe cases of these diseases.

Hemogenyx is developing two products based on a key finding made by Dr Vladislav Sandler, the Co-Founder and Chief Executive, for the $8-9 billion bone marrow / haematopoietic stem cell transplant market which could replace chemotherapy and radiation as a means of pre-transplant conditioning, as well as addressing the problem of stem cell donor availability and issues around relapse or cell rejection after transplantation. These two products are:

Conditioning product - CDX bi-specific antibodies which redirect a patient's own immune cells to eliminate unwanted blood stem cells preparing a patient for bone marrow transplantation;

Cell therapy product - Cell replacement product using Human Postnatal Hemogenic Endothelial Cells (Hu-PHEC) to generate cancer-free, patient-matched blood stem cells after transplant into the patient.

The products address a large and growing need and will be sold into a market that is already substantial. If successful, Hemogenyx's products will enable a much wider range of patients to be treated than is presently the case as the products should be applicable to the very many patients who are unfit for or, through the lack of suitable cell donors, unable to receive blood stem cell transplants at present.

Hemogenyx has, to date, made impressive progress on the Company's two products efficiently using its limited financial resources. With the GBP1.6million net of expenses raised during the listing, we expect to take the initial conditioning product to readiness for clinical trials and to make significant progress with our cell therapy product.

Update on Hemogenyx progress

I should take this opportunity to remind shareholders of the progress made since the reverse takeover and relisting. Overall the work is progressing successfully toward our goal of submitting an Investigational New Drug ("IND") application to the US Food and Drug Administration for our CDX antibodies product.

LakePharma, Inc. appointment

In October last year we announced the appointment of LakePharma, Inc. as our service provider for the development and manufacturing of our CDX bi-specific antibodies lead product. LakePharma will work with us through the product development process, from discovery to biomanufacturing, as we move toward readiness for clinical trials. LakePharma, the largest US-based biologics contract research organisation, is a significant partner bringing the relevant integrated antibody engineering and bioproduction expertise we need to advance our CDX product through the necessary preclinical stages to be ready to enter the clinic within our planned timetable.

University of Oxford Collaboration

In November last year we confirmed a collaboration with the University of Oxford to test new means of accelerating and improving the process by which transplanted blood stem cells grow and make healthy blood cells, and which promises to hasten the development of our Hu-PHEC technology.

Researchers at Hemogenyx will administer certain biologics from Oxford to stem cells in an attempt to accelerate and improve the engraftment of hematopoietic stem and progenitor cells in animal models. Engraftment is the process by which blood stem cells integrate into the bone marrow and make healthy blood. If successful, this approach has the potential to dramatically improve the efficiency and outcome of bone marrow transplants.

We will then be in a position to test whether this approach facilitates the conversion of Hu-PHEC into fully functional, transplantable blood stem cells. Our Hu-PHEC when developed and successfully tested will generate cancer-free, patient-matched blood stem cells and are the basis of our cell therapy product and have the potential, if all goes according to plan to improve the efficacy of the bone marrow transplantation therapy.

In addition, we expanded our material transfer agreement with a major US research university, ensuring the reliable supply of high-quality human tissues for the development of our Hu-PHEC cell therapy product.

Post-period end updates

Following the end of the period under review, we have been able to announce two additional items of significance, describing research progress. The first major item was the receipt of our first set of data results showing that developed by Hemogenyx CDX bi-specific antibodies are capable of attacking and eliminating cultured cells of the blood cancer, Acute Myelogenous Leukemia (AML), tested in vitro.

This is a significant development in the process needed to develop CDX antibodies to become a universally available conditioning product for patients undergoing bone marrow transplants as a treatment for serious blood diseases.

At the same time, we confirmed the filing of a provisional patent application relating to our development of a new type of humanised mice with a chimeric mouse-human blood system. This can be used to advance product development, as well as to model several other diseases and drug discovery applications. Using these new humanised mice should allow us to demonstrate that CDX bi-specific antibodies are effective in the treatment of AML, this time in vivo.

Of particular significance is that this new type of humanised mice allows us to extend our work to other disease models and the evaluation of specific drug candidates. Furthermore, this is of interest to large biopharmaceutical companies. Thus, in mid-March 2018 we announced a collaboration with a major US biotechnology company (with whom we were already working and from whom we had already received revenue) to use our humanised mice for this very purpose. The deal is revenue generating for the Company and is worth up to approximately $250,000 and we believe this has the potential to generate further income as the collaboration develops.

Financial Results

During the year the Group made a loss of GBP2,319,734 (2016: GBP470,839 loss). As at present, we remain within budget for the developments of our products.

Scientific Advisory Board & Board update

I have been Chairman of the Scientific Advisory Board since September 2017 and have been working with the Company to widen its expertise and to bring in advisers that can specifically help given the stage which the Company's product development has reached.

In March 2018, we were very pleased to welcome Dr Michael Shepard to our Scientific Advisory Board. Dr Shepard is a renowned cancer research specialist and his work led to the discovery and development of many successful cancer treatments including Herceptin/trastuzumab, an antibody used to treat breast cancer patients when he was at Genentech. Sales of Herceptin last year exceed $6.5 billion worldwide.

Our Scientific Advisory Board, under my Chairmanship brings together a number of experienced experts with extensive biotech and large pharma drug development experience and their calibre is a reflection of potential opportunity that our therapies present. Further additions are under consideration.

Earlier this month I extended my commitment to the Company and became Executive Chairman, replacing Robin Campbell, who has become a Non-Executive Director.

In November, we announced that Timothy Le Druillenec, Finance Director, stood down as a Director and at the same time as my appointment to the Board, Adrian Beeston stood down as a Non-Executive Director. I again extend my thanks to both Timothy and Adrian for their contribution to the successful completion of the Company's readmission and trading on the main market of the London Stock Exchange.

The Board have continued to demonstrate their confidence in the ongoing success of the business throughout the period under review and post-period end. I have elected to receive most of my remuneration in shares and collectively we remain confident that they should deliver significant shareholder return over the long term.

As a further sign of confidence, we were pleased to note that Cornell University, with whom we have an exclusive licence agreement relating to the patents covering the method of isolation of post-natal hemogenic endothelial cells, invented by Dr Sandler, elected to receive part payment for a sum due in a mixture of new shares and cash, rather than cash as previously expected.

Outlook

Our two main planned products are on track and should if fully developed and brought into use greatly reduce the dangers of patient conditioning procedures and create a new form of blood stem cell transplantation that has the potential to significantly improve the long-term success of bone marrow transplants and to transform the lives of patients diagnosed with serious blood diseases.

My fellow Directors and I believe that the Company is well-advanced on the planned development steps that were announced at Admission and we look forward to the next 12 months with confidence.

Prof Sir Marc Feldmann AC, FRS

MB BS, PhD, FRCP, FRCPath, FAA, F Med Sci

Chairman

Statement of Comprehensive Income

 
 Consolidated Statement of Comprehensive 
  Loss 
                                                                                Unaudited 
                                                                                Year Ended 
                                                          Year Ended 31        31 December 
 Continuing Operations                           Note     December 2017            2016 
 
 Revenue                                                                -                   - 
 
 Administrative Expenses                         6                787,362             447,151 
 Depreciation Expense                            11                33,614              11,870 
 
 Operating Loss                                                 (820,976)           (459,022) 
 
 Other income                                                     101,138 
 
 Finance Costs                                                   (10,741)            (11,817) 
 
 Reverse acquisition expense                     4            (1,631,007)                   - 
 
 Loss before Taxation                                         (2,361,599)           (470,839) 
                                                       ------------------  ------------------ 
 
 Taxation                                                               -                   - 
 
 Loss for the year attributable to 
  equity owners                                               (2,361,599)           (470,839) 
                                                       ------------------  ------------------ 
 
 Items that will be reclassified subsequently 
  to profit or loss: 
   Translation of foreign operations                             (36,652)              26,526 
                                                       ------------------  ------------------ 
 Other Comprehensive income for the 
  year                                                           (36,652)              26,526 
 
 Total comprehensive income/(loss) 
  to the year attributable to the equity 
  owners                                                      (2,398,251)           (417,787) 
 
 Basic and diluted (per share)                   10                (0.01)              (0.00) 
 

The notes to the financial statements form an integral part of these financial statements.

Statement of Financial Position

 
 Statement of Financial Position        Group 
 
                                                                          Unaudited          Unaudited 
                                                      Year Ended         Year Ended         Year Ended 
                                                     31 December        31 December        31 December 
                                        Note                2017               2016               2015 
                                       ------  -----------------  -----------------  ----------------- 
 
 Assets 
 
 Non-current assets 
 Property, plant and equipment             11            191,578            175,797                  - 
 Intangible asset                          12            257,525            281,577            234,771 
 Investment                                                    -                  -                  - 
 Total non-current assets                                449,103            457,374            234,771 
 
 Current assets 
 Trade and other receivables               15             69,784            162,059             41,295 
 Cash and cash equivalents                             1,876,655             87,223             47,390 
 Total current assets                                  1,946,439            249,282             88,685 
 
 Total assets                                          2,395,542            706,656            323,456 
                                               =================  =================  ================= 
 
 Equity and Liabilities 
 
 Equity attributable to shareholders 
 Paid-in Capital 
   Called up share capital                 16          3,600,514          1,010,849            255,935 
   Share premium                           17          7,341,056                  -                  - 
   Other reserves                          18            369,147                  -                  - 
 Reverse asset acquisition reserve          4        (6,157,894)                  -                  - 
 Foreign currency translation 
  reserve                                               (13,984)             22,668            (3,858) 
 Retained Earnings                                   (3,006,982)          (645,383)          (174,544) 
 Total Equity                                          2,131,857            388,134             77,533 
 
 Liabilities 
 Non-current liabilities 
 Borrowings                                20                  -            275,500            229,704 
 Total non-current liabilities                                 -            275,500            229,704 
 
 Current liabilities 
 Trade and other payables                  20            263,685             16,688              5,241 
 Current borrowings                        20                  -             26,335             10,979 
 Total Current Liabilities                               263,685             43,023             16,220 
 
 Total Liabilities                                       263,685            318,522            245,924 
                                               -----------------  -----------------  ----------------- 
 
 Total equity and liabilities                          2,395,542            706,656            323,456 
                                               =================  =================  ================= 
 
 
 Statement of Financial Position        Company 
 
                                                       Year Ended         Year Ended 
                                                      31 December        31 December 
                                         Note                2017               2016 
                                       --------  ----------------  ----------------- 
 
 Assets 
 
 Non-current assets 
 Loan to subsidiaries                     13              594,435                  - 
 Investment in subsidiary                 14            8,000,000                  - 
 Total non-current assets                               8,594,435                  - 
 
 Current assets 
 Trade and other receivables              16               66,013              1,680 
 Cash and cash equivalents                              1,748,337          1,045,723 
 Total current assets                                   1,814,350          1,047,403 
 
 Total assets                                          10,408,785          1,047,403 
                                                 ================  ================= 
 
 Equity and Liabilities 
 
 Equity attributable to shareholders 
 Paid-in Capital 
   Called up share capital                17            3,600,514            669,000 
   Share premium                          18            7,341,056            841,243 
 Other reserves                           19              369,147                  - 
 Retained Earnings                                    (1,165,532)          (606,535) 
 Total Equity                                          10,145,185            903,708 
 
 Liabilities 
 Current liabilities 
 Trade and other payables                 20              263,600            143,695 
 Total Current Liabilities                                263,600            143,695 
 
 Total Liabilities                                        263,600            143,695 
                                                 ----------------  ----------------- 
 
 Total equity and liabilities                          10,408,785          1,047,403 
                                                 ================  ================= 
 

Hemogenyx Pharmaceuticals Plc has used the exemption grated under s408 of the Companies Act 2006 that allows for the non-disclosure of the Income Statement of the parent company. The after tax loss attributable to Hemogenyx Pharmaceuticals Plc for the year ended 31 December 2017 was GBP558,997 (2016: GBP519,898).

Statement of Changes in Equity

 
 
   Statement of Changes in Equity 
   Group 
 
                                                                                                       Foreign 
                   Called                                                   Other        Reverse       currency 
                    up Share                   Share                        reserves     acquisition   translation   Retained                    Total 
                    Capital                     Premium                                  reserve       reserve        losses                      Equity 
----------------  --------------------------  --------------------------  ----------  --------------  ------------  --------------------------  ------------------------------- 
  As at 1 
   January 
   2016                              255,935                           -           -               -       (3,858)                   (174,544)                           77,533 
  Loss in year                             -                           -           -               -                                 (470,839)                        (470,839) 
  Other 
   Comprehensive 
   Income                                  -                           -           -               -        26,526                           -                           26,526 
----------------  --------------------------  --------------------------  ----------  --------------  ------------  --------------------------  ------------------------------- 
  Total 
   comprehensive 
   income for 
   the period                              -                           -           -               -        26,526                   (470,839)                        (444,313) 
  Issue of share 
   capital                           754,914                           -           -                                                                                    754,914 
----------------  --------------------------  --------------------------  ----------  --------------  ------------  --------------------------  ------------------------------- 
  As at 31 
   December 
   2016                            1,010,849                           -           -               -        22,668                   (645,383)                          388,134 
----------------  --------------------------  --------------------------  ----------  --------------  ------------  --------------------------  ------------------------------- 
 
 Loss in year                              -                           -           -               -             -                 (2,361,599)                      (2,361,599) 
  Other 
   Comprehensive 
   Income                                  -                           -           -               -      (36,652)                           -                         (36,652) 
  Total 
   comprehensive 
   income for 
   the year                                -                           -           -               -      (36,652)                 (2,361,599)                      (2,398,251) 
 Transfer to 
  reverse 
  acquisition 
  reserve                        (1,010,849)                           -           -       1,010,849             -                           -                                - 
 Recognition 
  of Hemogenyx 
  PLC equity 
  at reverse 
  acquisition                        669,000                     841,243           -         831,257             -                           -                        2,341,500 
 Issue of shares 
  for 
  acquisition 
  of subsidiary                    2,285,714                   5,714,286                 (8,000,000)             -                           -                                - 
 Issue of shares 
  to directors 
  for services                        30,000                      75,000           -               -             -                           -                          105,000 
 Issue of shares 
  - share 
  subscription                       571,429                   1,428,571           -               -             -                           -                        2,000,000 
 Share issue 
  costs                                                        (495,316)           -               -             -                           -                        (495,316) 
 Issue of shares 
  for debt 
  settlement                          44,371                     110,927           -               -             -                           -                          155,298 
 Issue of 
  options                                  -                           -      35,492               -             -                           -                           35,492 
 Issue of 
  warrants                                 -                   (333,655)     333,655               -             -                           -                                - 
----------------  --------------------------  --------------------------  ----------  --------------  ------------  --------------------------  ------------------------------- 
 As at 31 
  December 
  2017                             3,600,514                   7,341,056     369,147     (6,157,894)      (13,984)                 (3,006,982)                        2,131,857 
----------------  --------------------------  --------------------------  ----------  --------------  ------------  --------------------------  ------------------------------- 
 
 
 
 
 Statement of Changes in Equity Company 
 
                    Called up                                               Other       Retained 
                     Share Capital              Share Premium               reserves     earnings/(loss)            Total Equity 
----------------  --------------------------  --------------------------  ----------  --------------------------  -------------------------- 
  As at 1 
   January 
   2016                              649,000                     781,243           -                    (86,637)                   1,343,606 
  Loss in period                           -                           -           -                   (519,898)                   (519,898) 
  Other 
  Comprehensive 
  Income                                   -                           -           -                           -                           - 
----------------  --------------------------  --------------------------  ----------  --------------------------  -------------------------- 
  Total 
   comprehensive 
   income for 
   the 
   period                                  -                           -           -                   (519,898)                   (519,898) 
  Issue of share 
   capital net 
   of share 
   issue 
   costs                              20,000                      60,000           -                           -                      80,000 
----------------  --------------------------  --------------------------  ----------  --------------------------  -------------------------- 
  As at 31 
   December 
   2016                              669,000                     841,243           -                   (606,535)                     903,708 
----------------  --------------------------  --------------------------  ----------  --------------------------  -------------------------- 
 
  Loss in year                             -                           -           -                   (517,133)                   (517,133) 
  Other 
  Comprehensive 
  Income                                   -                           -           -                           -                           - 
  Total 
   comprehensive 
   income for 
   the 
   year                                    -                           -           -                   (558,997)                   (558,997) 
 Issue of shares 
  for 
  acquisition 
  of subsidiary                    2,285,714                   5,714,286           -                           -                   8,000,000 
 Issue of shares 
  to directors 
  for services                        30,000                      75,000           -                           -                     105,000 
 Issue of shares 
  - share 
  subscription                       571,429                   1,428,571           -                           -                   2,000,000 
 Share issue 
  costs                                    -                   (495,316)           -                           -                   (495,316) 
 Issue of shares 
  for debt 
  settlement                          44,371                     110,927           -                           -                     155,298 
 Issue of 
  options                                  -                           -      35,492                           -                      35,492 
 Issue of 
  warrants                                 -                   (333,655)     333,655                           -                           - 
----------------  --------------------------  --------------------------  ----------  --------------------------  -------------------------- 
 As at 31 
  December 
  2017                             3,600,514                   7,341,056     369,147                 (1,165,532)                  10,145,185 
----------------  --------------------------  --------------------------  ----------  --------------------------  -------------------------- 
 

Statement of Cash Flows

 
                                                                                                  Unaudited 
                                                                                                  Year Ended 
                                                                            Year Ended 31        31 December 
 Statement of Cash Flows Group                               Note           December 2017            2016 
 
 
  Cash flows generated from operating 
   activities 
  Loss before income tax                                                        (2,361,599)           (470,839) 
  Depreciation                                                11                     33,614              11,870 
  Other Non-cash items interest/professional 
   fees (shares issued)                                                             105,000              60,358 
  Interest income                                                                     (732)               (217) 
  Interest expense                                                                   11,473              12,035 
  Reverse Acquisition Expense                                 4                   1,631,020                   - 
  Share based payments                                        18                     35,492                   - 
 Working capital changes applicable to pre-acquisition 
  retained earnings                                                                 (1,145)                   - 
  Change in trade and other payables                                                  7,637               9,507 
  Change in trade and other receivables                                            (86,260)           (163,209) 
  net cash outflow used in operating activities                                   (452,979)           (540,495) 
                                                                         ------------------  ------------------ 
 
  Cash flows generated from financing 
   activities 
  Proceeds from issuance of equity securities                                     2,000,000             754,914 
  Share issue costs                                                               (383,871)                   - 
  Repayment of loans and borrowings                           20                  (154,422)                   - 
  Other current liabilities acquired at 
   acquisition                                                                    (245,000)                   - 
 
  Net cash flow generated from financing 
   activities                                                                     1,216,707             754,914 
                                                                         ------------------  ------------------ 
 
  Cash flows generated from investing 
   activities 
  Interest income                                                                       732                 217 
  Interest paid                                                                     (1,011)                   - 
  Cash acquired on acquisition                                                    1,098,640                   - 
  Purchase of property, plant & equipment                                          (64,257)           (188,785) 
                                                                         ------------------  ------------------ 
  Net cash flow generated from investing 
   activities                                                                     1,034,104           (188,567) 
                                                                         ------------------  ------------------ 
 
  Net increase in cash and cash equivalent                                        1,797,832              25,852 
 
  Effect of exchange rates on cash                                                  (8,400)              13,981 
 
  Cash and cash equivalents at the beginning 
   of the period                                                                     87,223              47,390 
                                                                         ------------------  ------------------ 
  Cash and cash equivalents at the end 
   of the period                                                                  1,876,655              87,223 
                                                                         ------------------  ------------------ 
 
 
                                                          Year Ended 
                                                          31 December       Year Ended 31 
 Statement of Cash Flows Company                Note         2017           December 2016 
 
 
  Cash flows generated from operating 
   activities 
  Loss before income tax                                      (558,997)           (519,898) 
 
  Other Non-cash items interest/professional 
   fees (shares issued)                                         105,000              80,000 
  Foreign exchange (gain) loss                                   19,176                   - 
  Interest income                                               (1,166)                   - 
  Share based payments                           18              35,492                   - 
  Change in trade and other payables                             23,459             132,278 
  Change in trade and other receivables                        (64,332)              29,487 
 
  net cash outflow used in operating 
   activities                                                 (441,368)           (278,133) 
                                                      -----------------  ------------------ 
 
  Cash flows generated from financing 
   activities 
  Proceeds from issuance of equity 
   securities                                                 2,000,000                   - 
  Share issue costs                                           (383,871)                   - 
 
  Net cash flow generated from 
   financing activities                                       1,616,129                   - 
                                                      -----------------  ------------------ 
 
 
  Cash flows generated from investing 
   activities 
  Interest income                                                 1,166                   - 
  Loan to subsidiary                                          (473,313)                   - 
                                                      -----------------  ------------------ 
  Net cash flow generated from 
   investing activities                                       (472,146)                   - 
                                                      -----------------  ------------------ 
 
  Net increase in cash and cash 
   equivalent                                                   702,614           (278,133) 
 
  Cash and cash equivalents at 
   the beginning of the period                                1,045,723           1,323,869 
                                                      -----------------  ------------------ 
  Cash and cash equivalents at 
   the end of the period                                      1,748,337           1,045,736 
                                                      -----------------  ------------------ 
 
 

Notes to the Financial Statements

   1.     General Information 

The Company is preclinical-stage biotechnology company focused on the discovery, development and commercialization of innovative treatments relating to bone marrow/hematopoietic (blood-forming) stem cell (BM/HSC) transplants for blood diseases, including leukaemia, lymphoma and bone marrow failure. The products under development are designed to address a range of problems that occur with current standard of care treatments.

The Company's registered office is located at 5 Fleet Place, London EC4M 7RD, and is listed on the London Stock Exchange.

   2.     Summary of Significant Accounting Policies 

The principal accounting policies applied in the preparation of these financial statements are set out below. These policies have been consistently applied to all the years presented, unless otherwise stated.

Basis of Preparation

The financial statements have been prepared in accordance with International Financial Reporting Standards ("IFRS") and IFRS Interpretations Committee (IFRS IC) interpretations as adopted for use by the European Union, and the Companies Act 2006. The financial statements have been prepared under the historical cost convention.

Basis of Consolidation

The consolidated financial statements comprise the financial statements of Hemogenyx Plc and its subsidiaries as at 31 December 2017. The financial statements of the subsidiaries are prepared for the same reporting period as the parent company, using consistent accounting policies.

All intra-group balances, transactions, income and expenses and profits and losses resulting from intra-group transactions that are recognised in assets, are eliminated in full.

Subsidiaries are fully consolidated from the date of acquisition, being the date on which the Group obtains control, and continue to be consolidated until the date that such control ceases. Please refer to note 4 for information on the consolidation of Hemogenyx LLC.

Hemogenyx Pharmaceuticals Plc has used the exemption grated under s408 of the Companies Act 2006 that allows for the non-disclosure of the Income Statement of the parent company. The after tax loss attributable to Hemogenyx Pharmaceuticals Plc for the year ended 31 December 2017 was GBP558,997 (2016: GBP519,898).

Research and development expenditure

   (i)            Research and development 

Expenditure on research activities, undertaken with the prospect of gaining new scientific or technical knowledge and understanding, is recognised in profit or loss as incurred.

Development activities involve a plan or design for the production of new or substantially improved products and processes. Development expenditures are capitalised only if development costs can be measured reliably, the product or process is technically and commercially feasible, future economic benefits are probable, and the Company intends to, and has sufficient resources to, complete development and to use or sell the asset. No development costs have been capitalized to date.

   (ii)           Clinical trial expenses 

Clinical trial expenses are a component of the Company's research and development costs. These expenses include fees paid to contract research organizations, clinical sites, and other organizations who conduct development activities on the Company's behalf. The amount of clinical trial expenses recognized in a period related to clinical agreements are based on estimates of the work performed using an accrual basis of accounting. These estimates incorporate factors such as patient enrolment, services provided, contractual terms, and prior experience with similar contracts.

   (iv)         Government grants 

Government grants relate to financial grants from governments, public authorities, and similar local, national or international bodies. These are recognised when there is a reasonable assurance that the Company will comply with the conditions attaching to them, and that the grant will be received. Government grants relating to research and development are off-set against the relevant costs.

Intangibles

Research and development

Research expenditure is written off as incurred. Development expenditure is written off as incurred, except where the Directors are satisfied that a new or significantly improved product or process results and other relevant IAS 38 criteria are met as to the technical, commercial and financial viability of individual projects that would require such costs to be capitalised. In such cases, the identifiable directly attributable expenditure is capitalised and amortised. The Group's view is that capitalised assets have a finite useful life and to that extent they should be amortised over their respective unexpired periods with provision made for impairment when required. Assets capitalised are not amortised until the associated product is available for use or sale. Amortisation is calculated using the straight-line method to allocate the costs of development over the estimated useful economic lives. Estimated useful economic life is assessed by reference to the remaining patent life and may be adjusted after taking into consideration product and market characteristics such as fundamental building blocks and product life cycle specific to the category of expenditure.

Intellectual property (IP)

IP assets (comprising patents, know-how, copyright and licenses) acquired by the Group as a result of a business combination are initially recognised at fair value or as a purchase at cost, and are capitalised.

Internally generated IP costs are written off as incurred except where IAS 38 criteria, as described in research and development above, would require such costs to be capitalised.

The Group's view is that capitalised IP assets have a finite useful life and to that extent they should be amortised over their respective unexpired periods with provision made for impairment when required. Capitalised IP assets are not amortised until the Group is generating an economic return from the underlying asset and as such no amortisation has been incurred to date as the products to which they relate are not ready to be sold on the open market. When the trials are completed and the products attain the necessary accreditation and clearance from the regulators, the Group will assess the estimated useful economic like and the IP will be amortised using the straight line method over their estimated useful economic lives.

Fixed assets

All property, plant and equipment is stated at historical cost less accumulated depreciation or impairment value. Cost includes the original purchase price and expenditure that is directly attributable to the acquisition of the items to bring the asset to its working condition. Depreciation is provided at rates calculated to write off the cost less estimated residual value of each asset over its expected useful economic life. Assets held under finance leases, if any, are depreciated over their expected useful economic life on the same basis as owned assets, or where shorter, the lease term. Assets are reviewed for impairment when events or changes in circumstances indicate that the carrying amount may not be recoverable.

The following rates are used:

 
 Computer equipment           33%   Straight line 
 Laboratory equipment   20% - 50%   Straight line 
---------------------  ----------  -------------- 
 

Impairment of non-financial assets

The Group is required to review, at least annually, whether there are indications (events or changes in circumstances) that non-financial assets have suffered impairment and that the carrying amount may exceed the recoverable amount. If there are indications of impairment then an impairment review is undertaken. An impairment charge is recognised within operating costs for the amount by which the carrying amount exceeds its recoverable amount. The recoverable amount is the higher of the asset's fair value less costs to sell and the value-in-use. In the event that an intangible asset will no longer be used, for example, when a patent is abandoned, the balance of unamortised expenditure is written off.

Impairment reviews require the estimation of the recoverable amount based on value-in-use calculations. Non-financial assets relate typically to investments in related parties and in-process development and patents, and require broader assumptions than for developed technology. Key assumptions taken into consideration relate to technological, market and financial risks and include the chance of product launch taking into account the stage of development of the asset, the scale of milestone and royalty payments, overall market opportunities, market size and competitor activity, revenue projections, estimated useful lives of assets (such as patents), contractual relationships and discount rates to determine present values of cash flows.

Investments

Equity investments in entities that are associates or subsidiaries are held at cost, less any provision for impairment. As there is no quoted price in an active market, fair value cannot be reliably measured.

Going Concern

The preparation of financial statements requires an assessment on the validity of the going concern assumption.

The Directors have reviewed projections for a period of at least 12 months from the date of approval of the financial statements. The financial statements have been prepared on the going concern basis. The Group's forecasts and projections, taking account of reasonably possible changes in trading performance, show that the Group should be able to operate within the level of its current available working capital and working capital facilities for the next 12 months. Therefore the Directors consider the going concern basis appropriate.

Financial Instruments

Financial assets and liabilities are recognised in the Company's statement of financial position when the Company becomes a party to the contractual provisions of the instrument. The Company currently does not use derivative financial instruments to manage or hedge financial exposures or liabilities.

Loans and receivables are non-derivative financial assets with fixed or determinable payments that are not quoted in an active market. They are included in current assets, except for maturities greater than 12 months after the end of the reporting period. These are classified as non-current assets. The Company's loans and receivables comprise Trade and Other Receivables and Cash and Cash Equivalents in the Statement of Financial Position.

Trade and Other Receivables and Payables

Trade and other receivables are amounts due from customers for merchandise sold or services performed in the ordinary course of business. If collection is expected in one year or less (or in the normal operating cycle of the business if longer), they are classified as current assets. If not they are presented as non-current assets.

Trade and other receivables are recognised initially at fair value, and subsequently measured at amortised cost using the effective interest method, less provision for impairment.

Other liabilities measured at amortised cost are obligations to pay for goods or services that have been acquired in the ordinary course of business from suppliers. The liabilities are classified as current liabilities if payment is due within one year or less (or in the normal operating cycle of the business if longer. If not, they are presented as non-current liabilities.

The liabilities are recognised initially at fair value, and subsequently measured at amortised cost using the effective interest method.

Impairment of Financial assets

The Company and Group assesses at each reporting date whether a financial asset is impaired and will recognise the impairment loss immediately through the consolidated statement of comprehensive loss.

Foreign currencies

Functional and presentation currency

The Company's presentation currency is the British Pound Sterling ("GBP"). The functional currency for the Company, being the currency of the primary economic environment in which the Company operates, is the British Pound Sterling. The individual financial statements of each of the Company's wholly owned subsidiaries are prepared in the currency of the primary economic environment in which it operates (its functional currency)

The Hemogenyx LLC financial statements have been translated into Pound Sterling in accordance with IAS 21 The Effects of Changes in Foreign Exchange Rates. This standard requires that assets and liabilities be translated using the exchange rate at period end, and income, expenses and cash flow items are translated using the rate that approximates the exchange rates at the dates of the transactions (i.e. the average rate for the period). The foreign exchange differences on translation of Hemogenyx LLC are recognized in other comprehensive income (loss).

Foreign currency transactions

Foreign currency transactions are translated into the functional currency using the exchange rates prevailing on the dates of the transactions. Foreign exchange gains and losses resulting from the settlement of such transactions and from the translation at period-end exchange rates of monetary assets and liabilities denominated in foreign currencies are recognized in profit and loss.

Share based payments

The Group has applied the requirements of IFRS 2 Share-based Payment for all grants of equity instruments.

The Group operates an equity-settled share option plan to certain shareholders. The fair value of the service received in exchange for the grant of options and warrants is recognised as an expense. Equity-settled share-based payments are measured at fair value (excluding the effect of non-market based vesting conditions) at the date of grant. The fair value determined at the grant date of equity-settled share-based payment is expensed on a graded vesting basis over the vesting period, based on the Group's estimate of shares that will eventually vest and adjusted for the effect of non-market based vesting conditions.

Fair value is measured by use of the Black-Scholes model. The expected life used in the models has been adjusted, based on management's best estimate, for the effects of non-transferability, exercise restrictions, and behavioural considerations.

On addition the Group issues equity-settled share-based payments to the directors and senior management ("Employee Share Options") and to its corporate finance advisers for assistance in raising private equity ("Non-employee Share Options"). Equity-settled share-based payments are measured at fair value at the date of grant for Employee Share Options and the date of service for Non-employee Share Options. The fair value determined at the grant date or service date, as applicable, of the equity-settled share-based payments is expensed, with a corresponding credit to equity, on a straight-line basis over the vesting period, based on the Group's estimate of shares that will eventually vest. At each subsequent reporting date the Group calculates the estimated cumulative charge for each award having regard to any change in the number of options that are expected to vest and the expired portion of the vesting period. The change in this cumulative charge since the last reporting date is expensed with a corresponding credit being made to equity. Once an option vests, no further adjustment is made to the aggregate amount expensed.

The fair value is calculated using the Black Scholes method for both Employee and Non-employee Share Options as management views the Black Scholes method as providing the most reliable measure of valuation. The expected life used in the model has been adjusted, based on management's best estimate, for the effects of non-transferability exercise restrictions and behavioural considerations. The market price used in the model is the issue price of Company shares at the last placement of shares immediately preceding the calculation date. The fair values calculated are inherently subjective and uncertain due to the assumptions made and the limitation of the calculations used.

Share Capital

Ordinary Shares are classified as equity. Equity instruments issued by the Hemogenyx Group are recorded at the proceeds received, net of direct issue costs.

Cash

Cash consist of cash bank deposit balances.

Taxation

Deferred Tax

Deferred income tax is recognised on all temporary differences arising between the tax bases of assets and liabilities and their carrying amounts in the financial statements, with the following exceptions:

-- where the temporary difference arises from the initial recognition of goodwill or of an asset or liability in a transaction that is not a business combination and, at the time of the transaction, affects neither accounting nor taxable profit or loss;

-- in respect of taxable temporary differences associated with investment in subsidiaries, associates and joint ventures, where the timing of the reversal of the temporary differences can be controlled and it is probable that the temporary differences will not reverse in the foreseeable future; and

-- deferred income tax assets are recognised only to the extent that it is probable that taxable profit will be available against which the deductible temporary differences, carried forward tax credits or tax losses can be utilised.

Deferred income tax assets and liabilities are measured on an undiscounted basis at the tax rates that are expected to apply when the related asset is realised or liability is settled, based on tax rates and laws enacted or substantively enacted at the statement of financial position date.

The carrying amount of deferred income tax assets is reviewed at each statement of financial position date. Deferred income tax assets and liabilities are offset, only if a legally enforcement right exists to set off current tax assets against current tax liabilities, the deferred income taxes related to the same taxation authority and that authority permits the Company to make a single net payment.

Income tax is charged or credited directly to equity if it relates to items that are credited or charged to equity. Otherwise income tax is recognised in the statement of comprehensive income.

Segmental Reporting

The Group's operations are located throughout in New York, USA with the head office located in the United Kingdom. The main assets of the Group, cash and cash equivalents, are held in United Kingdom and adequate amounts are transferred to the USA operating business on a quarterly basis on approval from the board.

The Group currently has one reportable segment - biotechnology company focused on the discovery, development and commercialization of innovative treatments relating to bone marrow/hematopoietic (blood-forming) stem cell (BM/HSC) transplants for blood disease.

New Accounting Standards and Interpretations in issue but not applied in the Financial Statements

i) New standards, amendments and Interpretations in issue but not yet effective or not (and in some cases have not yet been adopted by the EU):

The standards and interpretations that are issued, but not yet effective, up to the date of issuance of the financial statements are listed below. The Group intend to adopt these standards, if applicable, when they become effective. These are summarised below:

-- IFRS 15 - 'Revenue from contracts with customers' This standard deals with revenue recognition and establishes principles for reporting useful information to users of financial statements about the nature, timing and uncertainty of revenue and cash flows arising from an entity's contracts with customers. Revenue is recognised when a customer obtains control of a good or service and thus has the ability to direct the use and obtain the benefits from the good or service.

The standard replaces IAS 18 'Revenue' and IAS 11 'Construction contracts' and related interpretations. The standard is effective for annual periods beginning on or after 1 January 2018 and earlier application is permitted subject to EU endorsement. The Group does not expect that the adoption of IFRS 15 will result in a change to the accounting policy as the performance obligation and timing of recognition are consistent with those identified under IAS 18.

-- IFRS 16 - 'Leases' This standard replaces the current guidance in IAS 17 - 'Leases' and is a far-reaching change in accounting by lessees in particular. Under IAS 17, lessees were required to make a distinction between a finance lease (on balance sheet) and an operating lease (off balance sheet). IFRS 16 requires lessees to recognise a lease liability reflecting future lease payments and a 'right-of-use asset' for virtually all lease contracts.

-- IFRS 16 includes an optional exemption for certain short-term leases and leases of low-value assets; however, this exemption can only be applied by lessees. For lessors, the accounting remains substantially unchanged. IFRS 16 provides updated guidance on the definition of a lease (as well as the guidance on the combination and separation of contracts); under IFRS 16, a contract is, or contains, a lease if the contract conveys the right to control the use of an identified asset for a period of time in exchange for consideration.

The standard is effective for annual periods beginning on or after 1 January 2019 and earlier application is permitted subject to EU endorsement. The Group is currently assessing the impact of IFRS 16.

-- IFRS 9 - 'Financial Instruments' This standard replaces IAS 39. It includes requirements on the classification and measurement of financial assets and liabilities; it also includes an expected credit losses model that replaces the current incurred loss impairment model. The standard is effective for annual periods beginning on or after 1 January 2018 and earlier application is permitted subject to EU endorsement.

The Group does not expect that the adoption of IFRS 9 will result in a material changes to the carrying values and classification of financial assets and liabilities.

   3.     Significant accounting judgements, estimates and assumptions 

The preparation of the financial statements in conformity with International Financial Reporting Standards requires the use of certain critical accounting estimates. It also requires management to exercise its judgement in the process of applying the Company's accounting policies.

Estimates and judgements are continually evaluated, and are based on historical experience and other factors, including expectations of future events that are believed to be reasonable under the circumstances. The estimates and assumptions that have a significant risk of causing a material adjustment to the carrying amounts of assets and liabilities within the next financial year are discussed below.

The principal areas in which judgement is applied are as follows:

Warrants to be issued pursuant to IPO

Under terms of the share placement completed pursuant to the IPO there were a maximum of 62,021,429 warrants eligible to be issued eligible participants. As at 31 December 2017 43,627,283 warrants had been issued to eligible IPO participants who had been identified. A total of 18,394,146 warrants potentially are still to be issued however it is not known if or when these warrants will be issued as the identity of the holders is not known. The Group has not brought the value of the unissued warrants to account as at 31 December, 2017 as it cannot be reasonably ascertained if these outstanding warrants will ever be issued. The 18,394,146 warrants have a value of GBP112,274. Management has determined that a discount of 40% reasonable to allow for the probability of the identity of the warrant holders remaining unknown. After applying this discount a value GBP67,364 has not been brought to account in the Statement of Financial Position due to uncertainty.

Valuation of stock options

Management uses the Black Scholes model to value the share options. The model requires use of assumptions regarding volatility, risk free interest rate and a calculation of the value of the option at the time of the grant. Please see note 18 for details.

4. Reverse acquisition and LSE listing

On 4 October 2017, the Company acquired the entire issued share capital of Hemogenyx LLC, a private company incorporated in the United States, by way of a share for share exchange.

Although the transaction resulted in Hemogenyx LLC becoming a wholly owned subsidiary of the Company, the transaction constitutes a reverse acquisition in as much as the shareholders of Hemogenyx LLC own a substantial majority of the outstanding ordinary shares of the Company and 2 out of 6 members of the Board of Directors of the Company are Hemogenyx LLC shareholders and management.

In substance, the shareholders of Hemogenyx LLC acquired a controlling interest in the Company and the transaction has therefore been accounted for as a reverse acquisition. As the Company previously discontinued its investment activities and was engaged in acquiring Hemogenyx LLC and raising equity financing to provide the required funding for the operations of the acquisition and re-listing on the main market of the LSE, it did not meet the definition of a business according to the definition in IFRS 3. Accordingly, this reverse acquisition does not constitute a business combination and was accounted for in accordance with IFRS 2 Share-based payment and IFRIC guidance, with the difference between the equity value given up by the Hemogenyx LLC shareholders and the share of the fair value of net assets gained by the Hemogenyx LLC shareholders charged to the statement of comprehensive income as the cost of acquiring a main market LSE quoted listing.

Following the completion of the transaction the Company changed its name to Hemogenyx Pharmaceuticals Plc.

In accordance with reverse acquisition accounting principles, these consolidated financial statements represent a continuation of the consolidated financial statements of Hemogenyx LLC and include:

a. The assets and liabilities of Hemogenyx LLC at their pre-acquisition carrying amounts and the results for both periods; and

b. The assets and liabilities of the Company as at 31 December 2017 and it's results from 5 October 2017 to 31 December 2017,

On 4 October 2017, the Company issued 228,571,428 shares for all 21,923,076 shares of Hemogenyx LLC.

On 4 October 2017, the quoted share price of Hemogenyx plc was GBP0.035 and therefore this valued the investment in Hemogenyx LLC at GBP8,000,000.

Because the legal subsidiary, Hemogenyx LLC, was treated as the accounting acquirer and the legal Parent Company, Silver Falcon plc, was treated as the accounting subsidiary, the fair value of the shares deemed to have been issued by Hemogenyx LLC was calculated at GBP2,341,500 based on an assessment of the purchase consideration for an 100% holding in Hemogenyx Plc.

   The fair value of net assets of   Silver Falcon plc was as follows: 
 
                                    GBP 
 Cash and cash equivalents    1,098,640 
 Other assets                    60,641 
 Liabilities                  (448,800) 
                             ---------- 
 Net assets                     710,480 
                             ---------- 
 

The difference between the deemed cost and the fair value of the net assets acquired of GBP1,631,007 has been expensed in accordance with IFRS 2, Share based payments, reflecting the economic cost to the Hemogenyx LLC shareholders of acquiring a quoted entity.

The reverse acquisition reserve that arose from the reverse takeover is made up as follows:

 
                                                 Year Ended 31 
                                                  December 2017 
                                                            GBP 
 As at start of year                                          - 
 Pre-acquisition losses of Hemogenyx PLC 1            (799,763) 
 Hemogenyx LLC issued capital at acquisition2         1,010,849 
 Investment in Hemogenyx LLC3                       (8,000,000) 
 Reverse acquisition expense4                         1,631,020 
 
 
   As at end of year                                (6,157,894) 
                                                --------------- 
 

The movements on the Reverse acquisition reserve are as follows:

1. These consolidated financial statements present the legal capital structure of the Company. However, under reverse acquisition accounting rules, the Company was not acquired until 4 October 2017 and therefore the entry above is required to eliminate the initial retained losses of the Company.

2. Hemogenyx LLC had issued share capital of equivalent to GBP1,010,849 as at 4 October 2017. As these financial statements present the capital structure of the parent entity, the issue of equity by Hemogenyx LLC has been recorded in this reserve.

3. The Company issued 228,571,428 shares at GBP0.35 each, totaling GBP8,000,000 for the entire issued capital of Hemogenyx LLC. The above entry is required to eliminate the balance sheet impact of this transaction.

4. The reverse acquisition accounting is described in detail in note 4. The entry above represents the difference between the value of the equity issued by the Company, and the deemed consideration given by Hemogenyx LLC to acquire the Company.

   5.    Segment Information 

The Group has one reportable segment, the development of breakthrough therapies for the treatment of blood diseases, and administrative functions in the United Kingdom.

The following tables present expenditure and certain asset information regarding the Group's geographical segments for the year ended 31 December 2017:

 
 
 
                                  Year Ended     Year Ended 
                                 31 December    31 December 
                                        2017           2016 
                                    GBP            GBP 
Revenue 
Segment assets 
United Kingdom 
                                           -              - 
        *    Non-current 
-------------------------      -------------  ------------- 
 
        *    Current               1,814,350      1,047,416 
United States 
 
        *    Non-current             449,103        457,374 
-----------------------------  -------------  ------------- 
 
        *    Current                 132,089        249,282 
Total 
 
        *    Non-current             449,103        457,374 
-----------------------------  -------------  ------------- 
 
        *    Current               1,946,439        249,282 
 
Capital expenditure 
United Kingdom                             -              - 
United States                         64,257        188,785 
                               -------------  ------------- 
                                      64,257        188,785 
                               -------------  ------------- 
 

Capital expenditure consists of the purchase of property, plant and equipment.

All revenue is derived from single customer.

   6.    Expenses by nature 
 
                                                      Group                       Group 
                                                           Year Ended                  Year Ended 
                                                          31 December                 31 December 
                                                                 2017                        2016 
                                                                  GBP                         GBP 
                                            -------------------------  -------------------------- 
 
 
       Laboratory expenses                                     36,194                  22,533 
       Consumable equipment and supplies                       64,287                  65,236 
       Contractors & consultants                             164,534                 166,177 
       Travel                                                  19,494                    5,871 
       Staff Costs                                           246,919                 129,400 
       Insurance                                               13,820                  10,975 
       Other                                                   22,521                  22,000 
       Legal and professional fees                           189,786                   24,939 
       Foreign exchange loss / (gain)                          29,807                           - 
       Total Administrative Expenses                         787,362                 447,151 
                                            -------------------------  -------------------------- 
 
   7.      Employees 
 
                                    Group                    Group              Company        Company 
                                 Year Ended                Year Ended          Year Ended     Year Ended 
                                 31 December               31 December         31 December    31 December 
                                     2017                     2016                2017           2016 
                                               GBP                      GBP            GBP            GBP 
-----------------------   ------------------------  -----------------------  -------------  ------------- 
 
 Wages and salaries                        197,065                  129,400         41,325              - 
 Social security                            12,811                        -          2,634              - 
 Share options                              35,492                        -         35,492              - 
 Pension contributions                       1,551                        -              -              - 
-----------------------   ------------------------  -----------------------  -------------  ------------- 
 
                                           246,919                  129,400         79,451              - 
 -----------------------  ------------------------  -----------------------  -------------  ------------- 
 

Average number of people (including executive Directors) employed:

 
                                         Group          Group 
                                        Year Ended     Year Ended 
                                       31 December    31 December 
                                              2017           2016 
                                     -------------  ------------- 
 
       Research & development (?)                3              2 
       Administration                            2              1 
                                                 5              3 
                                     -------------  ------------- 
 
   8.    Auditors' remuneration 
 
                               Group                 Group 
                            Year Ended             Year Ended 
                            31 December            31 December 
                                2017                  2016 
                                        GBP                    GBP 
                       --------------------  --------------------- 
 
 
 Audit services                      40,000                 11,575 
 Non audit services                  36,000                 24,000 
                       --------------------  --------------------- 
                                     76,000                 35,575 
                       --------------------  --------------------- 
 
   9.      Income Tax 
 
                                                              Group           Group 
                                                                            Year Ended 
                                                          Year Ended 31     31 December 
                                                           December 2017       2016 
                                                                     GBP            GBP 
                                      -----------------  ---------------  ------------- 
 
 
 Current Tax: 
 Corporation tax on loss for 
  the year                                                             -              - 
 Deferred Tax                                                          -              - 
 Tax on loss on ordinary activities                                    -              - 
 
 Loss on ordinary activities before 
  tax                                                        (2,361,599)      (519,898) 
 
 Analysis of charge in the year: 
 Loss on ordinary activities 
  multiplied by weighted average 
  tax rate for the group of 25.54% 
  (2016: 20%)                                                  (596,451)      (103,980) 
 Disallowed items                                                391,839         54,145 
 Timing differences                                              (7,338)              - 
 Tax losses carried forward                                    (211,950)       (49,835) 
                                                         ---------------  ------------- 
 Current Tax charge                                                    -              - 
                                                         ---------------  ------------- 
 
 

The Group has accumulated tax losses arising in the UK of approximately GBP698,207 (Dec 2016: GBP295,198) that should be available, under current legislation, to be carried forward against future profits. No deferred tax asset has been recognised against these losses. The Group has tax losses carried forward in the US of GBP396,416 available under current rules until 2037. No deferred tax asset has been recognised against these losses.

   10.    Earnings per share 

The calculation of the Basic and fully diluted earnings per share is calculated by dividing the loss for the year from continuing operations of GBP2,361,599 (2016: GBP470,839) for the Group by the weighted average number of ordinary shares in issue during the year of 260,270,699 (2016: 145,166,853).

The weighted average number of shares is adjusted for the impact of the reverse acquisition as follows:

- Prior to the reverse takeover, the number of shares is based on Hemogenyx LLC, adjusted using the share exchange ratio arising on the reverse takeover; and

- From the date of the reverse takeover, the number of share is based on the Company.

Dilutive loss per Ordinary Share equals basic loss per Ordinary Share as, due to the losses incurred in 2017 and 2016, there is no dilutive effect from the subsisting share options.

   11.    Property, Plant & Equipment 
 
                                                         Property, 
 Group                                                plant & equipment 
                                                            GBP 
------------------------------------------------  ----------------------- 
 Costs 
 
 Balance, December 31, 2015                                             - 
   Additions                                                  188,785 
   Disposals                                                            - 
   Foreign exchange movement                                            - 
------------------------------------------------ 
 Balance, December 31, 2016                                   188,785 
   Additions                                                    64,257 
   Disposals                                                            - 
   Foreign exchange movement                                   (17,344) 
 Balance, December 31, 2017                                   235,698 
------------------------------------------------  ----------------------- 
 
 Accumulated depreciation and impairment losses 
 
 Balance, December 31 2015                                              - 
   Depreciation                                                 11,870 
   Disposals 
   Foreign exchange movement                                      1,117 
------------------------------------------------ 
 Balance, December 31, 2016                                     12,987 
   Depreciation                                                 33,614 
   Disposals 
   Foreign exchange movement                                     (2,482) 
 Balance, December 31, 2017                                     44,120 
------------------------------------------------  ----------------------- 
 
 Carrying amounts 
 Carrying value at December 31, 2015                                    - 
------------------------------------------------  ----------------------- 
 Carrying value December 31, 2016                             175,797 
------------------------------------------------  ----------------------- 
 Carrying value December 31, 2017                             191,578 
------------------------------------------------  ----------------------- 
 
   12.    Intangible Assets 

On 15 January 2015, the Company entered into an Exclusive License Agreement with Cornell University to grant to the Company patent rights to patent PCT/US14/65469 entitled "Post-Natal Hematopoietic Endothelial Cells and Their Isolation and Use" and rights to any product or method deriving therefrom.

The Company paid Cornell University $347,500, consisting of cash payments of $22,500 and a convertible promissory note in the amount of $325,000.

 
 Cost                     Intellectual 
                              Property 
                                   GBP 
-----------------------  ------------- 
 As at 15 January 2015               - 
 Additions                     228,829 
 Exchange movements              5,942 
 31 December 2015              234,771 
-----------------------  ------------- 
 Exchange movements             46,806 
 31 December 2016              281,577 
-----------------------  ------------- 
 Exchange movements           (24,052) 
 31 December 2017              257,525 
-----------------------  ------------- 
 

The carrying value of intangible assets is reviewed for indications of impairment whenever events or changes in circumstances indicate that the carrying value may exceed the recoverable amount. The products to which they relate are not ready to be sold on the open market. When the trials are completed and the products attain the necessary accreditation and clearance from the regulators, the Group will assess the estimated useful economic like and the IP will be amortised using the straight line method over their estimated useful economic lives. The directors are of the view that no impairment is required as the test results to date have been very positive and these products are now being moved on the clinical trial phase. Accordingly, the directors continue to believe that the products will eventually attain the necessary accreditation and clearance from the regulators and so no impairment has been considered necessary.

Amortisation will be charged to operating costs in the Statement of Comprehensive Income when the Group achieves product sales.

   13.    Loan to subsidiaries 
 
                                   Company        Company 
                                  Year Ended     Year Ended 
                                  31 December    31 December 
                                     2017           2016 
                                          GBP            GBP 
                                -------------  ------------- 
       Loan to Hemogenyx LLC          594,435              - 
                                      594,435              - 
                                -------------  ------------- 
 

Hemogenyx Pharmaceuticals PLC has made cumulative loan to Hemogenyx LLC of US$802,121 (GBP594,435) as at 31 December 2017. The loan is interest free and will be repaid when Hemogenyx LLC's operational cash flow allows. Management has undertaken an impairment assessment of the loan as at 31 December 2017 and has determined that that there was no impairment required. The interest rate and impairment assessment are reviewed on an annual basis.

   14.    Investments in subsidiary 
 
                                                                                     Proportion 
                                                                                      of ordinary 
                                                                                      shares held 
                                Address of the                                        directly by 
 Name                            registered office          Nature of business        parent (%) 
-----------------------------  --------------------------  -----------------------  ------------- 
 
                                  9 East Lookerman 
                                  Street, Suite 3A, 
   Hemogenyx Pharmaceuticals      Dover, Kent, Delaware, 
   LLC                            USA, 19901                  Biomedical sciences    100 
-----------------------------  --------------------------  -----------------------  ------------- 
 
   15.    Trade and other receivables 
 
                                    Group                            Group                            Company                          Company 
                                 Year Ended                        Year Ended                       Year Ended                        Year Ended 
                                 31 December                       31 December                      31 December                       31 December 
                                     2017                             2016                              2017                             2016 
                     ----------------------------------  -----------------------------  ----------------------------------  ----------------------------- 
       VAT 
        receivable                               64,784                              -                              61,013                              - 
       Other 
        receivables                                   -                        162,059                                   -                            180 
       Prepayments                                5,000                              -                               5,000                          1,500 
       Total trade 
        and other 
        receivables                              69,784                        162,059                              66,013                          1,680 
                     ----------------------------------  -----------------------------  ----------------------------------  ----------------------------- 
 

There are no material differences between the fair value of trade and other receivables and their carrying value at the year end.

No receivables were past due or impaired at the year end.

   16.    Called up share capital 
 
 Group                                      Class A          Class B 
                                             shares           shares        Ordinary shares             GBP 
                                             Number           Number            Number 
--------------------------------------  ---------------  --------------  ------------------  -------------- 
 As at 31 December 2015                      12,657,692               -                   -         255,935 
 Issue of shares to retain 
  contractual ownership percentage              496,154               -                   -               - 
  19 Feb 2016 2016 
 Issue of shares for cash various 
  dates 2016                                          -       8,769,230                   -         754,914 
--------------------------------------  ---------------  --------------  ------------------  -------------- 
 As at 31 December 2016                      13,153,846       8,769,230                   -       1,010,849 
 Transfer of LLC paid up capital 
  to Reverse Acquisition Reserve 
  4 Oct 2017                               (13,153,846)     (8,769,230)                   -     (1,010,849) 
 Issued capital of PLC at acquisition 
  4 Oct 2017                                          -               -          66,900,000         669,000 
 Issue of shares for acquisition 
  of subsidiary 4 Oct 2017                            -               -         228,571,428       2,285,714 
 Issue of shares to directors 
  4 Oct 2017                                          -               -           3,000,000          30,000 
 Issue of shares for cash 4 
  Oct 2017                                            -               -          57,142,857         571,429 
 Issue of shares for debt settlement 
  20 Oct 2017                                         -               -           4,437,075          44,371 
--------------------------------------  ---------------  --------------  ------------------  -------------- 
 As at 31 December 2017                               -               -         360,051,360       3,600,514 
--------------------------------------  ---------------  --------------  ------------------  -------------- 
 

Called up Share Capital (continued)

The issued capital of the Group for the period 1 January 2015 to 4 October 2017 is that of Hemogenyx LLC. Upon completion of the acquisition the share capital of Hemogenyx LLC was transferred to the Reverse acquisition reserve (see note4) and the share capital of Hemogenyx PLC was brought to account.

 
 Company                                                Number of 
                                                           shares        GBP 
-------------------------------------------------  --------------  ------------ 
 As at 1 January 2016                                  64,900,000       649,000 
 
 Issue of shares 11 Nov 2016                            2,000,000        20,000 
-------------------------------------------------  --------------  ------------ 
 As at 31 December 2016                                66,900,000       649,000 
 Issue of shares for acquisition of subsidiary 
  4 Oct 2017                                          228,571,428     2,285,714 
 
 Issue of shares to directors 4 Oct 2017                3,000,000        30,000 
 Issue of shares for cash 4 Oct 2017                   57,142,857       571,429 
 Issue of shares for debt settlement 20 Oct 2017        4,437,075        44,371 
-------------------------------------------------  --------------  ------------ 
 As at 31 December 2017                               360,051,360     3,600,514 
-------------------------------------------------  --------------  ------------ 
 
   17.    Share Premium 
 
 Group & Company 
                                                                 GBP 
----------------------------------------------------------  ---------- 
 As at 31 December 2016                                              - 
----------------------------------------------------------  ---------- 
 Issued capital of PLC at acquisition 4 Oct 2017               841,243 
 Issue of shares for acquisition of subsidiary 4 Oct 2017    5,714,286 
 Issue of shares to directors 4 Oct 2017                        75,000 
 Issue of shares for cash 4 Oct 2017                         1,428,571 
 Issue of shares for debt settlement 20 Oct 2017               110,927 
 Value of warrants issued                                    (333,655) 
 Share issue costs                                           (495,316) 
----------------------------------------------------------  ---------- 
 As at 31 December 2017                                      7,341,056 
----------------------------------------------------------  ---------- 
 

The issued share capital of Hemogenyx LLC did not have a share premium component.

   18.    Other Reserve 

Share options

 
                                         Year Ended     Year Ended 
  Group & Company:                        31 December    31 December 
                                          2017           2016 
                                                  GBP            GBP 
 
As at start of year                                 -              - 
Charge for the year - employees                35,492              - 
Fair value of warrants issued 
 in connection with share placement           333,655 
                                        -------------  ------------- 
 
  As at end of year                           369,147              - 
                                        -------------  ------------- 
 

The expense recognised for employee and non-employee services during the year is shown in the following table:

 
                                                    Year Ended      Year Ended 
  Group and Company:                                 31 December     31 December 
                                                     2017            2016 
                                                              GBP            GBP 
 
Expense arising from equity-settled share-based 
 payment transactions                                      35,492              - 
 
  Total expense arising from share-based payment        1,666,512              - 
  transactions 
                                                    -------------  ------------- 
 
 

Employee Plan

Under the Employee Plan ("EMP") share options are granted to directors and employees at the complete discretion of the Company. The fair value of the options is determined by the Company at the date of the grant to subscribe for Ordinary Shares on each of the following events/dates:

   (i)           Admission to the LSE ("Admission"); 
   (ii)          On the date falling six (6) months after Admission; 
   (iii)         On the date falling twelve (12) months after Admission; and 
   (iv)         On the date falling twenty four (24) months after Admission 

On the provision that the option holder remains a director of the Company.

Options granted to all other option holders vest in equal tranches of 12.5% every three months from 4 January, 2018, until fully vested.

The fair value of the options is determined using the Black Scholes method as stated in Note 2. The contractual life of each option granted is two years. There are no cash settlement alternatives.

Options are settled when the Company receives a notice of exercise and cash proceeds from the option holder equal to the aggregate exercise price of the options being exercised.

Non-Employee Plan

Under the Non-Employee Plan ("NEMP") share options are granted to non-employees at the complete discretion of the Company. The exercise price of the options is determined by the Company at the date of the grant. The options vest at the date of the grant.

The fair value of the options is determined using the Black Scholes method as stated in Note 2 and not the value of services provided as this is deemed the most appropriate method of valuation. In all cases non-employee option holders received cash remuneration in consideration for services rendered in accordance with agreed letters of engagement. The contractual life of each option granted ranges from two to five years. There are no cash settlement alternatives. Volatility was determined by calculating the volatility for three similar listed companies and applying the average of the four volatilities calculated.

Options are settled when the Company receives a notice of exercise and cash proceeds from the option holder equal to the aggregate exercise price of the options being exercised.

 
Group & Company:                     2017                      2017               2016                      2016 
                                      Number                WAEP(1)                Number                   WAEP 
                                                              pence                                        pence 
 
Outstanding at the                         -                      -                     -                      - 
beginning 
of the year 
Granted during the 
 year                             24,566,957                    3.5                     -                      - 
 
  Outstanding at end 
  of year                         24,566,957                    3.5                     -                      - 
                        --------------------  ---------------------  --------------------  --------------------- 
 
  Exercisable at end 
  of year                          1,780,214                    3.5                     -                      - 
                        --------------------  ---------------------  --------------------  --------------------- 
 

The weighted average remaining contractual life for the share options outstanding as at 31 December 2017 is 3.89 years (2016: n/a). The weighted average fair value of options granted during the year was 0.01 pence (2016: n/a). The exercise price for options outstanding at the end of the year was 3.5 pence (2016: n/a).

A schedule of options granted is below:

 
                                    Number options 
---------------------------------  --------------- 
 Dr. Robin Campbell                      3,560,429 
 Lawrence Pemble                         3,560,429 
 Professor Sir Marc Feldmann             5,340,643 
 Professor Alexander Tarakhovsky         2,670,321 
 Professor Koen Van Besien               2,670,321 
 Dr. Mark Pkkett                         2,670,321 
 Dr. Boris Shor                          2,670,321 
 Dr. Rita Simone                           712,086 
 Carina Sirochinsky                        712,086 
---------------------------------  --------------- 
 Total                                  24,566,957 
---------------------------------  --------------- 
 

The following table lists the inputs to the model used:

 
 
                          2017 
                         (EMP) 
--------------------  -------- 
 
Expected volatility 
 %                       39.56 
Risk-free interest 
 rate %                  0.472 
Expected life of 
 options (years)             2 
WAEP(1) - pence            3.5 
Expected dividend            - 
 yield 
Model used               Black 
                       Scholes 
--------------------  -------- 
 

(1) weighted average exercise price

Warrants

The share placement that completed on 4 October 2017 with the issue of 57,142,857 shares at GBP0.035 carried 1 for 2 wrrants for qualifying shareholders over 62,021,429 new ordinary shares at GBP0.04 per share. In order to qualify for these warrants the shareholder must have retained the shares for a period of 60 days after admission.

As at 31 December 2017 43,627,283 warrants had been issued to eligible IPO participants who had been identified. A total of 18,394,146 warrants potentially are still to be issued however it is not known if or when these warrants will be issued ` as the identity of the holders is not known. The 18,394,146 warrants have a value of GBP112,274 and applying a reasonable discount of 40% to allow for the probability of the identity of the warrant holders remaining unknown, an adjusted value GBP67,364 has not been brought to account in the Statement of Financial Position due to uncertainty. The following table lists the inputs to the models used for the two plans for the years ended 31 December 2017:

 
 
                             2017 
                              (NEMP) 
--------------------  ---  ------------- 
 
Expected volatility 
 %                                 39.56 
Risk-free interest 
 rate %                            0.472 
Expected life of 
 warrant (years)                       1 
WAEP(1) - pence                      4.0 
Expected dividend                      - 
 yield 
Model used                 Black Scholes 
-------------------------  ------------- 
 
   19.    Capital and Reserves 

The nature and purpose of equity and reserves are as follows:

Share capital comprises the nominal value of the ordinary issued share capital of the Company.

Share Premium represents consideration less nominal value of issued shares and costs directly attributable to the issue of new shares.

Other reserves represent the value of options in connection with share based payments, and warrants connected with share placements, issued by the Company.

Reverse asset acquisition reserve is the reserve created in accordance with the acquisition of Hemogenyx Pharmaceuticals LLC on 5 October, 2017 in accordance with IFRS 2.

Foreign currency translation reserve is used to recognize the exchange differences arising on translation of the assets and liabilities of foreign branches and subsidiaries with functional currencies other than Pounds Sterling, as well as the revaluation of intercompany loans.

Retained earnings represent the cumulative retained losses of the Company at the reporting date.

   20.    Non-current and current liabilities 
 
                                 Group                          Group                         Company                        Company 
                               Year Ended                     Year Ended                     Year Ended                     Year Ended 
                               31 December                    31 December                    31 December                    31 December 
                                  2017                           2016                           2017                           2016 
                     -----------------------------  -----------------------------  -----------------------------  ----------------------------- 
 
 
       Trade and 
        other 
        payables                             7,332                         16,688                          7,247                        143,695 
       Accruals and 
        deferred 
        income                             256,353                              -                        256,353                              - 
       Loan note 
       interest                                  -                         26,334                              -                              - 
       Loan notes                                -                        275,500                              -                              - 
       Total 
        liabilities                        263,685                        318,522                        263,600                        143,695 
 
       Current 
        liabilities                        263,685                         43,022                        263,600                        143,695 
 
       Non-current 
        liabilities                              -                        275,500                              -                              - 
 

Loan Notes

On 15 January 2015 Hemogenyx LLC issued a USD$325,000 unsecured convertible promissory note to Cornell University in partial payment of the license fee with that University. The promissory note bore interest at 5% per annum with the interest payable annually in arrears. The maturity date is the earlier of (1) after the Company receives a bona fide equity investment of not less than $5 million, (2) 14 January 2020, or (3) a change in control of the Company. The note was convertible into membership units at a price equal to the price obtained in the above-mentioned bona fide equity investment.

Post completion of the acquisition of Hemogenyx Pharmaceuticals LLC the loan note and accrued interest were repaid in full via a cash payment of GBP154,422 (USD$199,866.68) and the issue of 4,008,504 ordinary shares at 3.5 pence each in Hemogenyx Pharmaceuticals PLC with a value totalling GBP140,297 (USD$186,175).

The loan note and interest were fully repaid by 31 December 2017.

A schedule of movements in the loan note is set out in the table below:

 
                                    GBP 
---------------------------  ---------- 
 Balance 1 January 2016         240,683 
 Interest expense                12,035 
 Foreign exchange movement       49,117 
---------------------------  ---------- 
 Balance 31 December 2016       301,835 
 Interest expense                11,473 
 Repayment in cash            (154,422) 
 Repayment in equity issue    (140,298) 
                               (18,588) 
---------------------------  ---------- 
 Balance 31 December 2017             - 
---------------------------  ---------- 
 
   21.    Related party disclosures 

With effect from 11 November 2015, M6 Limited ("M6") entered into an agreement to provide web development, online marketing, mobile application development and marketing, content production, advertising, public relations, and lead generation services to the Company for a fee of GBP80,000. The Company has agreed with M6 to issue 2,000,000 Ordinary Shares at the Placing Price at Admission in settlement of monies owed to M6. As at 11 November 2016, 2,000,000 Ordinary Shares were issued to M6 as payment for their services; there were no transactions with M6 in 2017. Adrian Beeston, a director of the Company, is also a director of M6 and holds c.17 per cent. of the issued ordinary share capital of M6 Limited.

During the year, the Company paid GBP7,150 (2015: GBP20,239) to Dukemount Capital Plc in respect of rent. Peter Redmond, a Director of the Company, is also Director of Dukemount Capital Plc. As at the 31 December, 2017 there were no amounts owed to Dukemount in respect of rent (2016: GBP1,500). Peter Redmond resigned as a director of Dukemont Capital on 26 April 2017.

   22.    Financial instruments 

The Group's financial instruments consist of cash, amounts receivable, investment, and accounts payable and accrued liabilities and deferred payment.

Fair value of financial assets and liabilities

Fair values have been determined for measurement and/or disclosure purposes based on the following methods. When applicable, further information about the assumptions made in determining fair values is disclosed in the notes specific to that asset or liability.

The carrying amount for cash, accounts receivable, and accounts payable and accrued liabilities on the statement of financial position approximate their fair value because of the limited term of these instruments. The fair value of deferred payment approximates its fair value. The investment is carried at cost as it is not traded on an active market.

Fair value hierarchy

Financial instruments that are measured subsequent to initial recognition at fair value are grouped in Levels 1 to 3 based on the degree to which the fair value is observable:

-- Level 1 fair value measurements are those derived from quoted prices (unadjusted) in active markets for identical assets or liabilities; and

-- Level 2 fair value measurements are those derived from inputs other than quoted prices included within level 1 that are observable for the asset or liability, either directly (i.e. as prices) or indirectly (i.e. derived from prices); and

-- Level 3 fair value measurements are those derived from valuation techniques that include inputs for the asset or liability that are not based on observable market data (unobservable inputs).

The Group did not have any financial instruments in Level 1, 2 and 3.

Financial risk management objectives and policies

The Company has exposure to the following risks from its use of financial instruments

   --     Credit risk 
   --     Liquidity and funding risk 
   --     Market risk 

The following table sets out the categories of financial instruments held by the Company as at the year ended 31 December 2017 and period ended 31 December 2016:

 
                               Group                               Group                               Company                         Company 
                            Year Ended                           Year Ended                          Year Ended                       Year Ened 
                            31 December                          31 December                         31 December                      31 December 
                                2017                                2016                                 2017                            2016 
                ----------------------------------  -----------------------------------  ----------------------------------  --------------------------- 
 
 Assets 
 Trade and 
  other 
  receivables, 
  except 
  prepayments                               64,784                              162,059                              61,013                          180 
 Cash and cash 
  equivalents                            1,876,655                               87,223                           1,748,337                    1,045,736 
                                         1,941,439                              249,282                           1,809,350                    1,045,916 
                ----------------------------------  -----------------------------------  ----------------------------------  --------------------------- 
 
 Liabilities 
 Trade and 
  other 
  payables                               (263,685)                             (16,688)                           (263,600)                    (143,695) 
 
 Loan Notes & 
 interest                                        -                            (301,835)                                   -                            - 
                ----------------------------------  -----------------------------------  ----------------------------------  --------------------------- 
                                         (263,685)                             (318523)                           (263,600)                    (143,695) 
                ----------------------------------  -----------------------------------  ----------------------------------  --------------------------- 
 
 
 
 Group                     1 January   Cash flows              Non-cash changes               31 December 
                              2017                                                                2017 
                                                   ---------------------------------------- 
                                                    Share repayment    Foreign     Interest 
                                                                       exchange     charge 
                                                                       movements 
------------------------  ----------  -----------  ----------------  -----------  ---------  ------------ 
  Long-term borrowings 
  Short-term borrowings      275,500    (154,422)         (140,297)        7,746     11,473             - 
------------------------  ----------  -----------  ----------------  -----------  ---------  ------------ 
  Total                      275,500    (154,422)         (140,297)        7,746     11,473             - 
------------------------  ----------  -----------  ----------------  -----------  ---------  ------------ 
 
   a)   Credit risk 

The Group had receivables of GBPnil owing from customers (31 December 2016: GBP1,680).

All bank deposits are held with Financial Institutions with a minimum credit rating of AAA.

   b)   Liquidity and funding risk 

The Group regularly reviews its major funding positions to ensure that it has adequate financial resources in meeting its financial obligations. The Group takes liquidity risk into consideration when deciding its sources of funds. The principle liquidity risk facing the business is the risk of going concern which has been discussed in Note 2 (b).

   c)    Market risk 

Interest rate risk

The Company has floating rate financial assets in the form of deposit accounts with major banking institutions; however, it is not currently subjected to any other interest rate risk.

Based on cash balances as above as at the statement of financial position date, a rise in interest rates of 1% would not have a material impact on the profit and loss of the Company and such is not disclosed.

In relation to sensitivity analysis, there was no material difference to disclosures made on financial assets and liabilities.

Foreign currency risk

The Group operates internationally and has monetary assets and liabilities in currencies other than the functional currency of the operating company involved.

The Group seeks to manage its exposure to this risk by ensuring that where possible, the majority of expenditure and cash of individual subsidiaries within the Group are denominated in the same currency as the functional currency of that subsidiary.

The Group has not entered into any derivative instruments to manage foreign exchange fluctuations.

The following table shows a currency of net monetary assets and liabilities by functional currency of the underlying companies:

 
                                              Functional Currency 
                                  -------------------------------- 
 Currency of net                    Pound Sterling     US Dollars      Total 
  monetary assets/(liabilities) 
                                          GBP              GBP          GBP 
--------------------------------  ------------------  ------------  ---------- 
 
 Pound Sterling                            1,489,737             -   1,489,737 
 US Dollars                                        -       132,003     132,003 
--------------------------------  ------------------  ------------  ---------- 
 Total                                     1,489,737       132,003   1,621,740 
--------------------------------  ------------------  ------------  ---------- 
 

Capital risk management

The Group defines capital as the total equity of the Company. The Group's objectives when managing capital are to safeguard the Group's ability to continue as a going concern in order to provide returns for shareholders and benefits for other stakeholders and to maintain an optimal capital structure to reduce the cost of capital.

In order to maintain or adjust the capital structure, the Group may adjust the amount of dividends paid to shareholders, return capital to shareholders, issue new shares or sell assets to reduce debt.

Fair value of financial assets and liabilities

There are no material differences between the fair value of the Group's financial assets and liabilities and their carrying values in the financial statements.

   23.    Operating lease commitments 

The Group has office leasing commitments.

The total of future minimum lease payments under non-cancellable operating leases for each of the following periods:

 
                                                           Group & Company 
                                                            2017       2016 
                                                             GBP        GBP 
                                                      ----------  --------- 
       not later than 1 year                               8,671      4,286 
       later than 1 year and not later than 5 years            -          - 
       not later than 5 years                                  -          - 
----------------------------------------------------  ----------  --------- 
       Total Operating lease commitments                   8,671      4,286 
----------------------------------------------------  ----------  --------- 
 
   24.    Ultimate Controlling Party 

The Directors have determined that there is no controlling party as no individual shareholder holds a controlling interest in the Company.

   25.    Copies of the Annual Report 

Copies of the annual report will be soon be available on the Company's website at www.hemogenyx.com and from the Company's registered office, 5 Fleet Place London EC4M 7RD.

This information is provided by RNS

The company news service from the London Stock Exchange

END

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April 30, 2018 11:23 ET (15:23 GMT)

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