Futura Medical Share Discussion Threads

[lbo] 08/3/2023 14:02

The HCP website that was advertised by Petroc says 'when assessed against internationally accepted criteria for clinical effectiveness (Rosen and Araujo) the efficacy of Eroxon exceeded the minimal clinically important difference' And the HCP Brochure on the same website references the study 'Minimal clinically Important Difference Rosen et al 2011'But its now clear from that exact study that the MCID criteria were estimated based on regular adequately controlled and blinded oral ED studies.The Rosen study also clearly states in its limitations the results have not been replicated in 'non pharmacologic studies'So they are not internationally accepted criteria for 'non pharmacologi studies'or medical device gels which are known to have much higher placebo effect then oral pharmacologic placebos. In one study it was 3 times higher.So now its been shown the MCID is inappropriately being used in HCP marketing to make a indirect cross comparison to non regular inadequately blinded medical device gel studies.https://pubmed.ncbi.nlm.nih.gov/21855209/MCIDs were estimated using data from 17 randomized, double-blind, placebo-controlled, parallel-group clinical trials of the phosphodiesterase type 5 inhibitorlimitationsCurrent analyses were based on 17 clinical trials of tadalafil. Results need to be replicated in studies using other PDE5-Is or in nonpharmacologic intervention studies.

[lbo] 08/3/2023 13:57

As usual with the multi-ID ramper he cannot substantiate any of false and misleading claims. Like all his posts not all the relevant information is being published on a UK website and only biased information is being disclosed on the website as its known that Med3000 is not a ‘regular’ oral placebo! It is a medical device placebo gel that is being massaged in! Which are known to have higher placebo effects. Yet this is not being adequately disclosed by the rampers

˜some forms of bias, such as publication bias, should be considered as fraud’


petroc - 23 Feb 2023 - 21:53:12 - 16545 of 16566






Bias and Fraud

There are numerous biases in medical research that render evidence from such research systematically misleading. Some of these biases are exacerbated by conflicts of interest, including fantastic financial incentives. The most important biases in medical research include confirmation bias, design bias, analysis bias, and publication bias. Arguably, some forms of bias, such as publication bias, should be considered as fraud. The pervasiveness of bias in medical research justifies one of the premises of the master argument for medical nihilism. Medical research is malleable due to the many biases, and such malleability allows for the production of evidence that suggests medical interventions are effective, whether or not they are in fact effective.

[petroc] 08/3/2023 12:39

You didn't quote the whole thing, LiarBO.

'Partner-related problems and lack of efficacy represented the most important reasons for PDE5i discontinuation, although no significant difference among factors was detected. In conclusion, despite their high efficacy and easy administration, the discontinuation rate and dissatisfaction with PDE5i are still very high. Our data showed that no single factor plays a major role in PDE5i dropout, suggesting that the discontinuation rate is usually because of a combination of both medical problems and psychosocial and relational factors.'

'NO SINGLE FACTOR PLAYS A MAJOR ROLE IN PDE5i DROPOUT.'

So thank you for yet again publishing the evidence that shows you were lying when you said the main reason for giving up Viagra was lack of efficacy.

[lbo] 08/3/2023 10:06

LOL

Yes thanks again for confirming side effects is not an issue with PDE5 drugs!



Corona G., First-generation phosphodiesterase type 5 inhibitors dropout: a comprehensive review and meta- analysis, Andrology, 2016,



‘lack of efficacy represented the most important reasons for PDE5i discontinuation’


And Med3000 will still have the same ‘Partner-related problems’ as you left out what they were being ‘ reluctant medication-dependent intercourse’. As now it will just becomes reluctant medical device placebo gel dependent intercourse! And not sure a placebo medical device can help with catholic religious beliefs! ‘partner-related compliance, only partner’s religion (Catholic) was a significant factor’



And also just like you left out that the ‘rate was higher in younger subjects and in those reporting a higher prevalence of associated morbidities’. Or the other reason ‘ high cost’ which has already been referenced on Farmaline as being an issue too with the placebo med3000 gel. Especially when arousal gels made of the same alcohol, water, glycol and carbomer ingredients can be bought for less!

[petroc] 08/3/2023 10:04

BTW, for anyone interested in proper chat about Eroxon, head on over to LSE. They're currently discussing the availability of Eroxon in Europe. No negativity, no back biting, and most importantly, no LiarBO bashing the stock with lies and misinformation! LSE wisely took the decision to ban the lying manipulator over a year ago.

[petroc] 08/3/2023 09:55

You didn't quote the whole thing, LiarBO.

'Partner-related problems and lack of efficacy represented the most important reasons for PDE5i discontinuation, although no significant difference among factors was detected. In conclusion, despite their high efficacy and easy administration, the discontinuation rate and dissatisfaction with PDE5i are still very high. Our data showed that no single factor plays a major role in PDE5i dropout, suggesting that the discontinuation rate is usually because of a combination of both medical problems and psychosocial and relational factors.'

'NO SINGLE FACTOR PLAYS A MAJOR ROLE IN PDE5i DROPOUT.'

So thank you for yet again publishing the evidence that shows you were lying when you said the main reason for giving up Viagra was lack of efficacy.

[lbo] 08/3/2023 09:52

Even Trinity Research who are paid by Futura has contradicted the rampers and had to openly admit the hypothesised effects 'believes' to be happening by Futura are 'disputed'https://www.discovermagazine.com/health/the-erection-of-a-placebo˜There is no evidence for the evaporative mode of action from the clinical trials. To show that the evaporation is what makes MED3000 work, you'd need to compare it to a non-evaporative gel'https://www.ftc.gov/system/files/documents/public_statements/996984/p114505_otc_homeopathic_drug_enforcement_policy_statement.pdfProof is what separates an effect new to science from a swindle . . . . If a condition responds to treatment, then selling a placebo as if it had therapeutic effect directly injures the consumer. FTC v. QT, Inc.Trinity also admitted no mechanism of action has to be even shown to just get a low class medical device registered.But it does need to be shown and proven to substantiate its marketing claims of having any effect beyond a placebo or even arousal gel with the same alcohol, water, glycol and carbomer ingredients or fall foul of the FTC, ASA and the Courts.Trinity research:Presumably the effect is comparable to the cold-induced vasodilation (CIVD) that occurs with extremities such as toes and fingers. Despite being a well-known effect, the mechanisms of CIVD are still disputed, but the pathways involved could well be similar. Interestingly, the precise mechanism of action does not need to be elucidated for the regulators to be comfortable for a product to be approved as a medical deviceââ‚

[petroc] 08/3/2023 09:49

The multi-ID stock basher (aka LiamBooth, Leveraged, Citygirl, sbgae, LBO8 et al) is making contradictory claims to the results found in two clinical tests and a home use trial. The vast majority of users confirmed that Eroxon works. LiarBO can't show a single piece of evidence that shows otherwise, which is why he has to use spurious and unrelated links in an attempt to tar Eroxon.

[lbo] 07/3/2023 20:59

And the research that Futura references on their website actually proves the ramper is wrong yet again. Side effects are not the main reason for men discontinuing PDE5 inhibitors in that referenced research.



Corona G., First-generation phosphodiesterase type 5 inhibitors dropout: a comprehensive review and meta- analysis, Andrology, 2016,



‘lack of efficacy represented the most important reasons for PDE5i discontinuation’

So MED3000 with its even more questionable efficacy and again it was proven less efficacious even in the deficient FM71 test then the lowest dose of Tadalafi. Means MED3000 will have even higher dropout rates especially as the ramper also proved most men with Psychogenic ED will just spontaneously recover with no treatment at all!

[lbo] 07/3/2023 20:51

So now the ramper is admitting ‘spontaneous recovery’ occurs in ED without any treatment! Did that happen in FM71 also? So no treatment at all is effective 30% of time and even higher in some groups like those with no co-morbidity and aged 30 to 39. And what was the Futura baseline? So thanks yet again for highlighting why uncontrolled unblinded studies in ED are DEFICIENT and have not proven MED3000 is having any effect beyond a placebo gel in any adequately controlled study.



‘At the start of the trial, 62% of all participants were able to attain an erection that was firm enough for penetration’



And what percentage of users wont want a burning pain medical device dependent intercourse from the highly questionable efficacy MED3000 gell? Or wont like needing it to be massaged in? And what percentage wont like the high cost of being swindled into paying over the odds for basically a cooling medical device lubricant/arousal gel made of just alcohol, water and glycol? Which can have the same onset time as Med3000 but Med3000 was proven less effective then the lowest possible dose of Tadalafil? And cant even substantiate any effect beyond a placebo gel or that its effects in FM57 and FM571 were not just spontaneous recovery!

Some scam! And the rampers have now proven it themselves!

ROFLMAO





In age-specific analysis, spontaneous recovery of EF was the most common reason for respondents aged 30 -39 years (58.8%

The proportion of discontinuation due to spontaneous recovery of EF was greater in the non-comorbid group (47.7%)

[petroc] 07/3/2023 17:04

The multi-ID stock basher (aka LiamBooth, Leveraged, Citygirl, sbgae, LBO8 et al) is making contradictory claims to the results found in two clinical tests and a home use trial. The vast majority of users confirmed that Eroxon works. LiarBO can't show a single piece of evidence that shows otherwise, which is why he has to use spurious and unrelated links in an attempt to tar Eroxon.