Evgen Pharma Share Discussion Threads

[moneymunch] 16/5/2020 18:45

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Braveheart Investment Group #BRH
Evgen Pharma #EVG
Ekf Diagnostics Holding #EKF

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[moneymunch] 16/5/2020 10:16

Pharma company’s shares jump on talk of coronavirus clinical trial

May 15 2020


Shares in North West pharmaceutical business Evgen Pharma jumped by almost a third earlier today after news it was linked to a possible treatment to help COVID-19 patients.

Just after mid-day its stock was priced at 16.82p, having started the day at 12p per share.

The price later settled back and by 5pm stood at 13.75p per share, a 17.02% increase on the opening price.

The company, which has offices in Wilmslow and Liverpool, revealed in a stock exchange announcement that it is in discussions with a potential source of funds that would help pay for a clinical trial in COVID-19 patients.

Evgen is focused on the treatment of cancer and neurological conditions.

It is developing sulforaphane-based medicines, known as SFX-01, for the treatment of breast cancer and multiple other diseases.

Sulforaphane is a sulfur-rich compound found in vegetables like broccoli.


However, trials could show that it can help to alleviate respiratory problems in patients, commonly known as ARDS, or acute resipiratory distress syndrome.

This condition affects many COVID-19 patients.

The company statement said: “Evgen can confirm that it is in discussions with a potential source of funds that would help pay for a clinical trial in COVID-19 patients, with Evgen providing SFX-01 in support of such a trial.

“A further announcement will be made if these discussions are successful.”

Drugs discovery firm in potential breast cancer treatment breakthrough

In February this year the AIM-isted clinical stage drug development company announced that its long-standing collaboration with the University of Manchester had led to the discovery of a gene signature that may predict patient response to SFX-01 in advanced oestrogen receptor positive (ER+) breast cancer.

Evgen Pharma had previously announced positive results from the STEM trial of SFX-01 in metastatic breast cancer.

[moneymunch] 16/5/2020 09:54

Daily Mail coverage , courtesy of Pinapple on Lse. ;-)



Evgen Pharma, a drug development company, saw its shares shoot up 17 per cent, or 2p, to 13.75p as it confirmed it was in discussion with a 'potential source of funds'.

It is hoping to bag some money to explore whether its SFX-01 drug, being developed to treat some forms of cancer and containing compounds similar to those found in broccoli, could work to treat Covid-19.

[moneymunch] 16/5/2020 09:48

or US, isn't SFX-01 a phase 11 detox promoter which also protects lungs from damage by activating the Nrf2 gene??? Gla ;-)

Therapeutic Solutions International Leverages Filed and Issued Intellectual Property to Develop COVID-19 Nutraceutical Candidate: QuadraMuneâ„¢

Published: May 05, 2020


OCEANSIDE, California, May 5, 2020 /PRNewswire/ -- Therapeutics Solutions International, Inc., (OTC Markets: TSOI) announced the filing of a patent application covering QuadraMuneâ„¢, a nutraceutical developed to address issues of susceptibility, inflammation, and viral immunity, for COVID-19 patients.

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"QuadraMune, as the name applies, consists of four unique ingredients that in tandem provide synergism in reducing inflammation," said Tim Dixon, President, and CEO of TSOI and co-inventor of the patent. "We have of course included pterostilbene, a very potent inhibitor of inflammatory molecules, along with sulforaphane, a phase II detox promoter which also protects lungs from damage by activating the Nrf2 gene [9], EGCg (epigallocatechin gallate), extracted from green tea that can stimulate T cells [10], inhibit pathological immunity [11], and also protect the lungs, and thymoquinone which comes from the plant nigella sativa that suppresses autophagy, potential antiviral mechanistic effects on cells [12], and has been demonstrated to stimulate NK cells [13] which are antiviral."

[moneymunch] 16/5/2020 09:06

Could even be a French Connection!! ;-)


Translated from French to English...Gla ;-)

Coronanvirus: Nutrinov laboratory to launch research to evaluate the efficacy of sulforaphane

Thursday April 30

Around the world, the race is on to find treatments for the coronavirus. Near Rennes, a laboratory specializing in health and nutrition wants to launch a clinical trial on sulforaphane, a natural compound with antiviral properties.

Doctors often say, by being careful what you eat, people can ease their symptoms and heal faster. Several epidemiological studies have notably identified the important role of fruits and vegetables. A healthy diet and physical activity, for example, reduce the risk of cancer.

Some substances are known for their antiviral properties. One of them is of particular interest to researchers and scientists in the Nutrinov laboratory located near Reindeer. He specializes in health and nutrition. Its researchers are particularly interested in sulforaphane, present in cruciferous vegetables such as broccoli and kale. It has several properties that participate in cell protection. It has also been shown to have antiviral properties.

A prophylactic and curative effect against covid-19?

"This molecule there, we know that it has antiviral, antibacterial and anticancer properties. We have done clinical studies with people who had prostate cancer. We have shown that it can help slow the evolution of pathology "explain Dr. Bernard Cipolla, surgeon oncologist in urology and Théo Efstathiou who heads the Nutrinov Analyzes & Research laboratory.

"In terms of antiviral activity, we conducted another clinical study in 2014 on mice targeted to pulmonary edema. We injected the H1-N1 virus in mice. A fortnight before, we had given sulforaphane and we noticed a clear reduction in the symptoms of pulmonary edema "indicates Théo Efstathiou.

Currently, there are no clinical studies on sulforaphane versus covid-19, "so we are forced to use therapeutic approaches based on previous research. Sulforaphane has been shown to be safe for consumption and that it is commercially available. I think it can be an important treatment available to the citizen in the current viral pandemic "continues the boss of the laboratory Nutrinov.

Nutrinov and its researchers therefore hope to be able to launch a clinical study to assess the efficacy of sulforaphane against the current virus.

[moneymunch] 16/5/2020 09:01

Lol, Cheers mesquida, this appears to be a great opportunity for some serious upside on funding for SFX-01 Covid-19 patient trials, and still somewhat under the radar. Gl ;-)

ps fair enough The Stig, just be nice.;-)))

[mesquida] 16/5/2020 08:49

Seems an appropriate point at which to thank you, moneymunch, for your numerous contributions on this board over the past six weeks. They have proved to be invaluable. Keep up the good work !

[moneymunch] 16/5/2020 08:43

EVG are in collaboration with the prestigious University of Rochester Medical Center in the US, for the evaluation of SFX-01 for Kidney disease, which is now associated with Covid-19. The University is now heavily involved in Covid-19 research, and so it's conceivable that funding could come from one of the US agencies funding research , such as BARDA.....not long before we find out. Gla ;-)

[moneymunch] 16/5/2020 08:05

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[toffeeman] 15/5/2020 22:21

Nobster

That gap closed today

[moneymunch] 15/5/2020 18:15

Ps those not in on positive confirmation of funding, will be green with envy, Sulforaphane green...:-)))

[moneymunch] 15/5/2020 18:11

Yep, extremely exciting for those invested, and perhaps still under the radar given the timing of the Rns, I'm fairly certain that anyone who sold into today's rise will greatly regret doing so....what value for a Bio with a highly promising treatment for Covid,19 , the funding could also be from a Major pharma which would propel the share price skywards.and maybe the reason for the swift departure of Evgen's CEO if they wanted their own man at the helm, but even if it's from one of the UK or US charitable agencies, this will go ballistic when confirmed ...and of course if positive results were observed then this could conceivably be the star share , eclipsing all others..Gla Holders and fingers crossed. ;-)

[nobbygnome] 15/5/2020 17:56

And from a TA point of view that gap is not far off being closed ta last!

[nobbygnome] 15/5/2020 17:56

Yes you have to think there will be a good ris eon Monday and beyond. If and when they announce the funding of the trial it should really take off and of course time is ofthe essence!

[mesquida] 15/5/2020 17:48

£50 m market cap does not seem that far-fetched to me.

[mesquida] 15/5/2020 17:44

Zak Mir was speculating about a possible rise to 40p in his webcast this morning, and that was BEFORE the RNS. Could be an interesting few months ahead of us.

[moneymunch] 15/5/2020 17:38

.Surprised this didn't finish higher...potential transformational funding news coming soon, for Covid-19 patient trials...Exciting or what!!!??? Gla :'l

Evgen can confirm that it is in discussions with a potential source of funds that would help pay for a clinical trial in Covid-19 patients, with Evgen providing SFX-01 in support of such a trial.

[moneymunch] 15/5/2020 14:28

The abrupt departure of the CEO suggests rather than charitable, the funding potentially could from a commercial background such as Major pharma, and so hopefully not too long before the next update. Gla :-)