Evgen Pharma Share Discussion Threads

[wololol] 11/11/2022 13:20

You might get your 100k purchase at the right price clock. What's your target 4.5p to buy?

[clocktower] 11/11/2022 12:14

Agreed but it's got the Friday blues with a couple of larger sells.

[georgie pie] 11/11/2022 12:04

This will do well

[clocktower] 11/11/2022 11:51

Until the next news, one just has to sit tight and relax about the share price whatever it does but if it does fall because of tired holders I am sure those of us that have funds will stock up further. So relax :-)

[givmesunshine] 11/11/2022 08:32

Morning

nice and quiet , get the feeling we will move up from here as there is little appitite to sell and cant really buy much .. with lots to come on the hoirzon ,seems like a good entry level for a newcomer

[clocktower] 10/11/2022 16:21

See a couple of bigger sells just now - surely your not freeing up cash from here to buy FLX Wololol.

PS. You can say that about liquidity W but the MM can do that because they know it's more or less only the institution that will have that sort of number, or a couple of big holders who are unlikely to sell down at that price but at .60 that's not really that huge but granted decent if it continues - I will keep an eye on it for now.

[georgie pie] 10/11/2022 15:49

I like the fact there is only 275m shares here, this will move very fast.

[wololol] 10/11/2022 15:39

Nice one clock. Re liquidity at flx the bid is fully loaded at the mo. Can sell £15k no problem 2 mill shares on only 500 mill in issue so it moves fast like this. I have more in this though, again bid is fully loaded so should move up quickly on buying pressure

[clocktower] 10/11/2022 15:35

I wish you every luck with that Wololol but at present this is far more liquid and that is part of the trouble with little AIM stocks that are sub 1p - millions of shares but I certainly hope it turns out in your favour and not that of yump who clearly has a gripe because of previous losses in the stock.

However, if this hits 8p soon, I tell you what, I will have a punt and buy 200k if still under .70 as you have such faith and to be fair it does have a reasonable amount of cash and debt but growing sales.

Could do with more investors here though, as many take to short term views, buy in the morning - sell a couple of hours latter on so many stocks - the MM love those folks.

[wololol] 10/11/2022 15:26

Ok let's talk about Flx when it doubles in less than 2 months. Just trying to share my insights with what I will know will happen. Evg looking good buyers coming in now. Strongest day in the markets for months, inflation coming down, war going to end great time to buy. Just need more liquid cash. Any cash should be put into bombed out shares now.

[clocktower] 10/11/2022 14:29

Wololol trying to get buyers for FLX by any chance?

As you know I looked at it but I much prefer this as the other is mega high risk and some disagree with you on the thread over there. Maybe worth a very small punt but with a major institution selling down that still has 45 million shares, more risk to downside imo.

This has funds without any further oe deals to 2025 - how long will FLX cash last?

Still, lets not talk about FLX here but you can always pm me with the reasons you are so sure about FLX.

[wololol] 10/11/2022 14:16

Wish I had more funds to buy. The only other stock I own is Falanx which will double in the next 2 months so can't sell any there.

[clocktower] 10/11/2022 14:06

The upside is potential huge, the downside very limited as I expect there are buyers waiting to snap them up, if a bored or needy seller appears. In fact although I have a large amount, I would add another 100k if the offer was once again around my average, as I expect further deals to be announced and long term huge possibilities.

So as I said, I will top slice at 8p and then wait and see the rest of my holding does over the long term.

Still, its good that so many are still hanging in and not ditching for small short term gains.

[georgie pie] 10/11/2022 10:32

I'd say most that want in are already in here and sitting tight for next update.

[mesquida] 10/11/2022 10:10

Not a single share traded so far today, amazing after all the activity that we saw here earlier this week.

[georgie pie] 10/11/2022 08:06

This will be rising soon, before next update around end of month and this is a good entry price point.

[lovewinshatelosses] 09/11/2022 11:17

I have never been able to get a feel for the direction of travel in this one...had a target price to buy another little side pot for a trade the other day, but just missed it on that decent rise. Ultimately hoping not to get the chance though! That last presentation was the best one the BOD have done since I have been a shareholder here, IMO. Probably gave them a level of real confidence that perhaps they did not feel previously, and which came across to those of us watching. But it never pays to get ahead of yourself with AIM stocks, so until the next (hopefully positive) update, be prepared for the share price to do pretty much anything :)

[givmesunshine] 09/11/2022 09:55

Not taking much to move this - I think I could get it to 6p or 3p on my own !!!GLA

[givmesunshine] 08/11/2022 20:44

LWHL

Agree, The body language was very positive in the presentation, and very proffesional.. I still dont think that market has took the Stalicla deal into account at all - and the MBC case is pretty compelling - Thats my top bet to meet the "consideraby longer cash runway" qoute - been 2 years now postive outcome of the current investigation will lead to something - I wouldn't be suprised if its a potential partner request that is the cause for the MBC trial in manchester .. Phizher name has been dropped a few times .. but probably a smaller Pharma outfit IMO

[lovewinshatelosses] 08/11/2022 19:00

Good breast cancer update and this will retest the year highs in a flash, IMO. And then some. Not before time either! Patiently waiting. GLA.

[givmesunshine] 08/11/2022 15:00

This was an intersting closing statement in the last RNS

"In the meantime, we are also focussing on our new and significant partnership with Stalicla SA and are driving our breast cancer programme forward in collaboration with the Manchester Breast Centre. We continue to explore partnering opportunities in the context of a considerably longer cash runway, with the prospect of significant further non-dilutive cash inflows from our partners."

Would love to know what EVG are discussing - obviously run a tight ship and there was nothing to highlight the Stalicla deal was about to get sealed

[givmesunshine] 08/11/2022 12:59

Looking forward to an update on the below - could drop at any point ..

Evgen has generated encouraging data with SFX-01 in mBC in a Phase II clinical trial. Since the commencement of this trial, the class of drugs known as CDK4/6 inhibitors have increasingly been adopted in these patients. Evgen is broadening the investigation into how SFX-01, in combination with other treatments, can improve outcomes for patients with HR+ breast tumours that have become resistant to this relatively new class of agents. This includes research into STAT3 and pSTAT3, a protein that controls transcription of information from DNA to messenger RNA; and SHP2, a non-receptor protein tyrosine phosphatase that is associated with many cancers including breast cancer.

In particular, we are expanding our work with Professor Rob Clarke at the Manchester Breast Centre with in vitro pre-clinical work to assess the impact of SFX-01 in CDK4/6 inhibitor resistance models. An increasing body of in vitro data from these models shows that SFX-01 may suppress tumour growth and metastasis in patients who have become resistant to CDK4/6 inhibitors. Encouragingly, SFX-01 reduces the viability and mammosphere colony formation of palbociclib-resistant tumour cell lines in vitro.

In addition, this extended collaboration will include in vivo models to provide the optimum support for clinical trial design and/or licensing in patients with ER+ve/HER2-ve breast cancer, where CDK4/6 inhibitors such as palbociclib are showing weakening effectiveness. Evgen anticipates data from both in vitro and in vivo work later in the year.

[clocktower] 07/11/2022 15:43

It will be 8p before I get excited Mick1909.

[givmesunshine] 07/11/2022 15:31

Yup - it takes a bit of patience to build up a position here

[mick1909] 07/11/2022 14:53

Low liquidity works both ways good news and it will explode