Evgen Pharma Share Discussion Threads

[nobbygnome] 29/5/2018 10:50

Just bought another 25k.

With regard to IMM I still haven't stopped laughing. I see che is ramping his insider trade to the rafters with no effect 😂😂😂😂8514;😂ԅ14;😂😏;

[teddy boy1] 29/5/2018 09:01

I notice that at 8.27am someone bought 22 shares Why would anyone do this? Any ideas?

With regard to IMM ,the comments smack of desperation ! A nice little rise for anyone who managed to get out at the top (not many,I suspect!) but I am predicting that this will be back in the red by the end of the day.


Evgen is a much better bet by miles and those who have sufficient insight and belief will be richly rewarded within the next month. I am buying some more this morning and will continue to top up as funds become available.

[teddy boy1] 28/5/2018 23:15

The more research I do on Evgen Pharma the more confident I become. I truly believe that this is a company with a big future but more importantly it will buy cancer sufferers extra time.

[teddy boy1] 28/5/2018 23:15

The more research I do on Evgen Pharma the more confident I become. I truly believe that this is a company with a big future but more importantly it will buy cancer sufferers extra time.

[teddy boy1] 28/5/2018 10:45

PDT - Interesting ,but not at all surprising. SFX-01 is shaping up to be a big breakthrough in extending the life span of cancer sufferers .

I am confident that the interim report will confirm this and then it will be full steam ahead. This , of course will be reflected in a much higher share price.

I shall be looking to top up my investment a number of times over the next 2 or 3 weeks.

[pdt] 28/5/2018 08:23

One of the exciting aspects of SFX-01 is that it can potentially be used against so many other cancers particularly where resistance to a treatment has occurred. Here is an example just published relating to bladder cancer treatment;

"TRAIL attenuates sulforaphane-mediated Nrf2 and sustains ROS generation, leading to apoptosis of TRAIL-resistant human bladder cancer cells"



Once the interim trial results are known I suspect there will be surge in interest in collaborations in this area if they are positive.

[teddy boy1] 26/5/2018 23:54

I am pleased that you are in agreement with my City friends.Seems to me that the share price should be higher ,but I can see it trending up nicely between now and the results.(if the last couple of days is anything to go by ,the process may have already begun)

[nobbygnome] 26/5/2018 21:27

Well they have a drug with a well described MOA dosed at the appropriate level! It is such a contrast to IMM which is a dog's dinner from a scientific and dosing point of view.

Oh and it stands a very good chance of working. With a response rate of 20% or higher, the price will be way higher.

The contrast with IMM couldn't be starker.....

Nobby

[teddy boy1] 26/5/2018 12:53

I very recently met up with a few of my "City" friends and the word is that there is much more interest in this share than there ever was with IMM. It might have something to do with the cancer aspect but I am assured by more than one person that it is being watched very carefully and that it is being recommended as a BUY by some firms. That is good enough for me!

[nobbygnome] 25/5/2018 16:33

LOL I really am a persona non grata. I assure you that I really am quite a pleasant person....

Ho hum

Nobby

[teddy boy1] 25/5/2018 16:28

And we shall have the money to fund our adventure! ( From the money we make on Evgen Pharma)

Seriously though, even if he does go on a bit ,a lot of what he says makes sense .To put the record straight : I have never met Nobby or even been in contact or spoken to him!

[purple11] 25/5/2018 15:26

TEDDY AND NOBBY ARE OFF ON A GREAT ADVENTURE GL

[teddy boy1] 25/5/2018 15:13

The spread is now very narrow, another indication that the shares are in short supply/high demand!

[nobbygnome] 25/5/2018 15:12

The interim results are due in the next month. The magic no they need to achieve is a 20% response rate at 6 months.

Oh and the chart looks absolutely primed for further rises IMHO!

[teddy boy1] 25/5/2018 14:34

The 12.59 trade (AGAIN SHOWN LATE!) - £7884 -price 21.90 which is shown as a sell is really a BUY!

This demonstrates to me that the market makers are short of stock and are desperately trying to hold the price back(against its will!)


DO NOT BE FOOLED! This share is in much demand so do not let go of yours!

[teddy boy1] 25/5/2018 13:36

Tricks are afoot! The 10.56 AM ,£16900 trade ,which has only just appeared, is NOT a sell. It is most definitely a BUY ! How do I know It is mine!

[bernymadoff] 25/5/2018 09:29

Looking primed now to rise into interim results announcement next month

[sharesoc] 24/5/2018 14:00

Evgen Pharma present at our Manchester growth company seminar on the 19th June. This may be of interest to potential investors and current shareholders, there are limited places at this event!

[purple11] 24/5/2018 12:51

asking 23.4 to buy atm...

[bernymadoff] 24/5/2018 01:09

They're not buys. It's a rollover

[l0ngterm] 23/5/2018 15:53

Was this just walked down for those 2 x 100k buys?

[timbo003] 21/5/2018 23:59

A few more nuggets from last week's meetings which are worth recording for prosperity (whilst I still remember):

* For the ongoing STEM study, SF stated that we should not place much emphasis on overall survival (OS) time, as this is not extended significantly using other treatments such as Pfizer's IBRANCE. However, IBRANCE does improve Progression free survival and Clinical Benefit Ratio (CBR), so the efficacy outcome to look out for in Evgen's study is CBR.

* Naturally occurring Sulforaphane is the enantiomerically pure (R) isomer, SFX-01 is made with the corresponding racemate (i.e. a 50/50 mix of R and S enantiomers). The calculations to determine the dose used in the two ongoing clinical trials have taken this into account.

* The half life of Sulforaphane in plasma is approximately 2.5 hours, but this is not what determines the twice daily dosing schedule in the Breast cancer study (STEM), what is more important is the half life in the effect compartment, which is considerably longer than 2.5 hours.

* The main metabolites of Sulforaphane (glutathione, cysteine and N acetyl cysteine conjugates) have biological activities similar to sulforaphane (which is not always the case with metabolites of other drugs)