C4X Discovery Holdings PLC PDMR Shareholdings (0457S)

TIDMC4XD

RNS Number : 0457S

C4X Discovery Holdings PLC

06 March 2019

C4X Discovery Holdings plc

("C4XD", "C4X Discovery" or the "Company")

PDMR Shareholdings

6 March 2019 - C4X Discovery Holdings plc (AIM: C4XD), a pioneering drug discovery company, announces that Dr Clive Dix, Chief Executive Officer, has today purchased 40,650 ordinary shares of 1 pence each in the Company ("Ordinary Shares"), at a price of 61.5 pence per Ordinary Share (the "Dealing"). Following the Dealing, Dr Clive Dix holds 1,455,586 Ordinary Shares, which represents an interest in 2.5% of the Company's issued share capital.

The notification below, made in accordance with the requirements of the EU Market Abuse Regulation, provides further detail.

Notification and public disclosure of transactions by persons discharging managerial responsibilities and/or persons closely associated with them:

 
 1     Details of the person discharging managerial responsibilities/person closely associated 
 a)    Name                                                          Dr Clive Dix 
      ------------------------------------------------------------  ------------------------------------------ 
 2     Reason for the notification 
      -------------------------------------------------------------------------------------------------------- 
                                                                     Chief Executive Officer, Director 
  a)    Position/status 
      ------------------------------------------------------------  ------------------------------------------ 
 b)    Initial notification/Amendment                                Initial Notification 
      ------------------------------------------------------------  ------------------------------------------ 
 3     Details of the issuer, emission allowance market participant, auction platform, auctioneer 
        or auction monitor 
      -------------------------------------------------------------------------------------------------------- 
 a)    Name                                                          C4X Discovery Holdings plc 
      ------------------------------------------------------------  ------------------------------------------ 
 b)    LEI                                                           213800UHNL82E323O870 
      ------------------------------------------------------------  ------------------------------------------ 
 4     Details of the transaction(s): section to be repeated for (i) each type of instrument; (ii) 
        each type of transaction; (iii) each date; and (iv) each place where transactions have been 
        conducted 
      -------------------------------------------------------------------------------------------------------- 
 a)    Description of the financial instrument, type of instrument   1p ordinary shares 
 
        Identification code 
                                                                      ISIN GB00BQQ2RV18 
      ------------------------------------------------------------  ------------------------------------------ 
 b)    Nature of the transaction                                     Purchase of Ordinary Shares 
      ------------------------------------------------------------  ------------------------------------------ 
 c)    Price(s) and volume(s)                                         Price(s) per Ordinary Share    Volume(s) 
                                                                       GBP0.615                       40,650 
      ------------------------------------------------------------  ------------------------------------------ 
 d)    Aggregated information                                         Price       Volume(s) 
                                                                       GBP0.615    40,650 
                                                                                  ---------- 
      ------------------------------------------------------------  ------------------------------------------ 
 e)    Date of the transaction                                       6 March 2019 
      ------------------------------------------------------------  ------------------------------------------ 
 f)    Place of the transaction                                      London Stock Exchange - AIM 
      ------------------------------------------------------------  ------------------------------------------ 
 

Name of authorised official of issuer responsible for making notification: Brad Hoy, Chief Financial Officer of the Company.

--ENDS-

For further information, please contact:

C4X Discovery Holdings plc

Clive Dix, Chief Executive Officer [phone]

Panmure Gordon (UK) Limited (NOMAD and Broker)

Freddy Crossley, Emma Earl (Corporate Finance) [phone]

James Stearns (Corporate Broking)

Consilium Strategic Communications

Mary-Jane Elliott, Chris Gardner, Matthew Neal [phone]

About C4X Discovery

C4X Discovery aims to become the world's most productive drug discovery engine by exploiting cutting edge technologies to design and create best-in-class small-molecule candidates targeting a range of high value therapeutic areas. The company's goal is to drive returns through early-stage revenue-generating deals with the pharmaceutical industry.

C4X Discovery has a state-of-the-art suite of proprietary technologies across the drug discovery process. The company's innovative DNA-based target identification platform (Taxonomy3(R)) utilises human genetic datasets to identify novel patient-specific targets leading to greater discovery productivity and increased probability of clinical success. This is complemented by C4XD's novel drug design platform which comprises two innovative chemistry technologies, Conformetrix and Molplex, that combine 4D molecular shape analyses (based on experimental data) with best-in-class computational chemistry. This provides new and unprecedented insight into the behaviour of drug molecules, enabling the production of potent selective compounds faster and more cost effectively than the industry standard.

C4X Discovery is advancing its in-house pipeline that is primarily focused on the high value therapeutic areas of inflammation, neurodegeneration and cancer (including immuno-oncology) with a number of new drug candidates identified and further progress made towards the pre-clinical licensing discussions. In selecting new targets and executing new drug discovery programmes, C4X Discovery focuses on high-value disease areas that are the subject of significant licensing activity and will continue to also maximise value from opportunistic areas such as addiction and diabetes. The Company recently signed a licensing agreement with Indivior for a pre-clinical addiction programme worth up to $294 million.

The Company was founded as a spin-out from the University of Manchester. It has a highly experienced management team and Board who have delivered significant value creation within the healthcare sector historically and have enabled C4XD to reach multiple value inflexion points since IPO. For additional information please go to: www.c4xdiscovery.com

This information is provided by RNS, the news service of the London Stock Exchange. RNS is approved by the Financial Conduct Authority to act as a Primary Information Provider in the United Kingdom. Terms and conditions relating to the use and distribution of this information may apply. For further information, please contact [e-mail] or visit www.rns.com.

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March 06, 2019 06:19 ET (11:19 GMT)