Avacta Share Discussion Threads

[cheshire pete] 10/9/2024 22:14

This may interest you repins, lol.

From LSE.

[pwhite73] 10/9/2024 14:03

Ok I have withdrawn the last sentence but you all know what I mean. The first cohorts started in August 2021 here we are in September 2024 and they are still presenting results from Phase 1a the very earliest of Phases.

They should be on Phase 3 by now but in order to do so they would need to show and proof efficacy to their peers in medical journals and to the FDA. This is something they have not done or unable to do.

My view is its the second of the two. In my opinion the markets said to AVCT we can't take this any further with the existing 15 year CEO in place. He was removed and replaced by another medical CEO but the same problems exist. No compelling or demonstrable evidence of efficacy at the therapeutic level.

[stmcn] 10/9/2024 12:22

Hi Divmad - no justification for PW71’s libellous comment but the (highly extended/indeterminate) time taken on this P1 is ruinous to both credibility and AVCT business plan. The facts are, the new CEO has not yet brought any clarity on the timelines and any workings behind the scenes appear stalled - AVCT is a purely ‘faith’ based hold at the moment.

[divmad] 10/9/2024 08:17

Would you mind repeating that directly to the CEO, and her legal counsel?

[pwhite73] 10/9/2024 06:59

Still presenting news from Phase 1a after three years FFS. If AVA6000 worked the drug would be seeking permission from the FDA to enter Phase III.

[blackvulture] 09/9/2024 16:41

SP being held down to let the shorter out. Nothing more.

[stmcn] 09/9/2024 15:32

Boring, insignificant RNS - more drivel, little / no real news … hence the negative response in the share price Hardly justified the announcement overhead. What we need is 1) when is P1 done; 2) do the results justify p2 and when does that start..

[amanitaangelicus] 09/9/2024 12:53

Trying to get interest for a future deal or farm in even earlier. Need Phase 2 imho. Enjoy the dribble of not much news

[meijiman] 09/9/2024 09:36

Yes I can't imagine he would go there to announce that 'it's a reet big flop'. But stranger things have happened. Here's hoping for a positive update on the data.

[bbd2] 09/9/2024 08:23

And the news flow begins!

[robers98] 09/9/2024 05:47

Avacta to present updated clinical data on AVA6000 at the European Society for Medical Oncology (ESMO) Congress

[amanitaangelicus] 07/9/2024 05:31

Alphaproteo Deep Mind- the game changer. Could be good for affirmer tech. Just saying. GLA.

[abbynat] 06/9/2024 19:47

16.48 a quite small buy of 337.000 was marked up! does it mean anything, will it change the price come monday? interesting though.

[blackvulture] 06/9/2024 13:58

2 days lots of buys share price not moved. My take is M&Ms letting the shorters out before news, and there will be a lot of news in the coming weeks.

[jacktrax] 06/9/2024 10:33

11 or 12 RNS starting from Monday till end of November , fingers crossed

[amanitaangelicus] 04/9/2024 08:57

The gravy train that keeps giving. Ps where has Smith gone? The lo gets Phase 1 trial? Yup, taking a very long time now ( rarely good news in my experience)

[squire007] 03/9/2024 16:00

Jogging on then .... :-))

[1347] 03/9/2024 15:41

Ah the arrogance, only you do I suppose? Yes I do to the level that I need to and to say there are no 'direct' alternatives is not really the point, the fact is there are alternatives, JakKnife and others have highlighted them several times.

[bonzo] 03/9/2024 14:44

1347 you don't seem to understand the reported data or the approval process. And there are no alternatives in development which would compete directly with this product.

[1347] 03/9/2024 14:19

For the umpteenth time, there is no quantifiable data on efficay and they've not even started a Phase 2 after 3 years, come back when there is something new to discuss. If you can't see the company are playing for time then that's your look out. It's also been pointed out several times that the alternatives are advancing at a faster rate than something that's re-using Dox, which has been around years. 'Investors' are getting played here in my opinion. All quiet on the Affimer front.

[fieldhouse] 03/9/2024 14:04

An expert in medical trials are you 1347 ?
No MTD found and proven safely established .
Encouraging signs of efficacy with patients on extended trial
Two weekly cohorts now undergoing tolerance and more detailed analysis for fap sensitivety
The medical oncologists have shown to be very encouraged by progress so far .

Yes,the path is slow but thorough

[1347] 03/9/2024 12:22

No, no don't think I will 'trot along', it's interesting and moderately amusing to see how long Avacta can spin a Phase 1 trial out for, they've already managed to spin it out longer than the Affimer worlds best tests fiasco. Also good to keep an eye on these 'investing genuises' that buy into these jam tomorrow fairytales. The ex CFO is not hanging about though, he's getting rid of what he can just as soon as he can and he's away on his toes next month with his smash and grab proceeds.