Amryt Pharma Share Discussion Threads

[papillon] 02/6/2018 12:14

Thanks for the link, Bermudashorts.

Good to hear from you again, diamondstar. I've mentioned before that licensing in Novelion/Aegerion's other commercial product would be another great deal that AMYT could make, after the success of licensing in Lojuxta.

I did notice in Novelion's latest quarterly results (1st quarter 2018) that whilst Juxtapid's sales were significantly down for the quarter compared to the corresponding quarter in 2017 (US$13.4m against US$16m), myalept's were very, very, slightly up (US$14.1m against US$14m).



Let's hope that Lojuxta sales haven't suffered in 2018 like those of Juxtapid! I wonder if the decrease in Juxtapid sales is because Aegerion were selling the drug to patients they weren't supposed to and Novelion have had to curtail those sales? Possible, because QLT only merged with Aegerion to form Novelion in December 2016.

EDIT: I had a look at the sales figures for Juxtapid for the 4 quarters of 2017 and they are volatile. I wonder if that is due to how and when the money is reimbursed to Novelion/Aegerion?

[bazworth] 02/6/2018 10:42

That would be good news!!

[diamondstar1] 02/6/2018 10:20

Novelion has just received positive CHMP opinion yesterday for their metreleptin product for partial lipodystrophy in Europe. Would be great if Amryt were able to in-license a second product, such as metreleptin. I am sure that Novelion do not have strong marketing capabilities in EU, so seems possible that Amryt, who are already selling Lojuxta on behalf of Novelion/Aegerion, might also be selected as a licensing partner. Watch this space.

[bazworth] 31/5/2018 22:25

Agreed😃

[papillon] 31/5/2018 22:04

It's well worth reading JimbobTechstock's excellent posts today over on the lse bb as he takes Bronxville to task and completely demolishes Bronxville's recent attacks on Aegerion (and by association, AMYT).

[papillon] 31/5/2018 12:48

Excellent post, JimbobTechstock. Mirrors my thoughts that AMYT have an excellently qualified, proactive BoD, who are going about things the correct way, unlike, as you state, the majority of AIM listed bio's. AMYT is NOT your usual run of the mill AIM listed fantasy company. I hope the share price multi-bags, but nothing can be taken for granted.

PS. If I was Bronxville I'd cease his one man AMYT bashing and jump back on the AMYT bandwagon. I think that could be very profitable for him.

PPS. I'm unable to post on the lse, buy someone ought to post that GSK "corruption & bribery" link on the lse bb.

[papillon] 31/5/2018 11:23

I see Bronxville is continuing his attack on the ethics of Aegerion with an article from 28/2/2018 ... "Doctor pleads guilty as part of Aegerion drug misbranding probe".

"A pediatric cardiologist from Georgia has pleaded guilty to divulging information about his patients to Aegerion Pharmaceuticals in 2013, as the Cambridge-based company was looking for ways to boost sales of cholesterol drug Juxtapid by promoting it for off-label uses.

During a hearing on Wednesday in Boston federal court, Eduardo Montaña pleaded guilty to violating the Health Insurance Portability and Accountability Act, or HIPAA. According to a court filing, Montaña admitted that he provided an Aegerion sales representative with a list of 280 young patients under his care who could potentially receive the drug.

At the time, however, Juxtapid was only approved by the FDA for adults with high cholesterol who also suffered from a particular rare disease. Last year, Aegerion pleaded guilty to misbranding Juxtapid and agreed to pay $40 million in fines. The case against Montaña arose out of that investigation"

However this case against Aegerion pales into insignificance compared to this bribery case (and fine) against one of the world's largest pharmaceutical companies, GlaxoSmithKline (GSK)



Bronxville's argument is that AMYT are tainted by employing ex Aegerion employees as managers. LET'S HOPE THAT AMYT DON'T EMPLOYEE ANY EX GSK EMPLOYEES! :-).

Unfortunately Bronxville could post a similar article about "corruption" against almost all major drug companies similar to the one he has shown against Aegerion.

PS. I took Bronxville off filter when removing JimbobTechstock off filter.

I think Bronxville's one man crusade against AMYT is getting rather boring. Not that it affects the AMYT share price one iota, no doubt much to his disappointment.

[jimbobtechstock] 31/5/2018 08:01

I'm not looking for a multibagger here, which perhaps is why the herd keep clear. It's an interesting company with a solid and broad BOD. I've never seen an AIM start-up set out with a revenue stream and a development arm, it makes sense from a practical POV because they won't have the usual roadblock if/when they get approval for a new indication for AP101.

Typically AIM bios are faced with a choice: sell the drug or go alone to market. The former puts them at the mercy of Big Pharma who will be looking to get the asset as cheap as possible. The latter puts them at the mercy of the capital markets which know the cost and risk of getting a drug to market, setting up distribution etc, and would likely do what they've done to MTFB and trade it as low as possible to maximise dilution and leave only the backers with the deepest pockets able to partake in every placing with a chance of winning. Dilute out the rest. (e.g Paratek took on $140m of debt post-approval to get to market - their antibiotic is more costly to market than MTFBs on account of economy of scale when targeting hospital settings, but indicates the huge cost of getting to market).

AMYT will be ideally placed, if they get positive EB results or are successful in the regulatory quest to start selling AP101/Episalvan for the conditions listed in the March update under the existing European Marketing Approval.

Not saying it's going to be plain sailing, there's still risks, but those risks are underpinned by the Lojuxta business as well as AP101 having an existing albeit currently untapped approval.

Therefore I am happy to invest in AMYT not on a typical AIM basis 'boom or bust' but on a risk vs reward basis where the bottom should be underpinned by the breadth of the business and the upside perhaps currently I'm looking at 40p+ as a best case scenario so a bag, but not a multibag. For me at least. And a LTH so I'm not lurching from month to month with a leveraged position, just shares in my SIPP, plus a few in my ISA which I will add again to if it's back under 17p

[papillon] 30/5/2018 19:46

Well AMYT is definitely NOT a fantasy company. They are, unfortunately, far too prevalent on AIM. MTV, CTAG, CICC & BNN immediately come to my mind. No doubt others can think of many other examples. Companies that are listed just to provide the BoD & advisors with a comfortable living by peddling a fantasy to PI's. Some, like AFG, are downright frauds.

I also believe (let's hope my belief is proved correct!) that AMYT is being well managed by a capable BoD. I came across another biotech for the first time today, AKR, that, on the face of it and according to posters on the AKR bb, seems to be extremely poorly managed. The share price is down from a high of over 600p to under 30p in just under 5 years as investor confidence in the company evaporates. That's a 20 fold fall in the AKR share price Let's hope that in 5 years time the AMYT share price is the exact opposite of AKR and that it has risen 20 fold in that time! Fingers crossed, as always! :-). Let's hope I live long enough to see it! LOL.

[papillon] 30/5/2018 17:54

No problem, Bermudashorts.

I'm continuing to hold AMYT in the hope that a fantastic RNS will transform the AMYT share price and this bb. I dream of the AMYT share price becoming a multi-bagger after a fantastic RNS is released. I suppose that dream is the reason we all continue to hold our shares. Fingers crossed, as always!

PS. JimbobTechstock posted yesterday that it's a "Great time to accumulate IMO". Which is basically the same message I posted 7 days ago ....... "The current low AMYT sp, whilst we are awaiting news, has it's benefits so don't knock it. It enables those holders who want a cheap top up to do so in the safe knowledge that AMYT is woefully undervalued at the current price"

I gambled on a T20 at the current low share price in the hope that we receive great news in the meantime. If we don't get that fantastic RNS before the middle of June I'll have the option of buying all, or some, of those T20 shares for a (hopefully) cheap top up. Fingers crossed we get good news before then as I'd dearly love to make a short term, cash, profit! :-)

[bermudashorts] 30/5/2018 16:32

Papillon, yes, you're quite right, you did indeed specify upon news (apologies)

[papillon] 30/5/2018 16:15

"Papillon - have seen plenty of Amryt bashing but where are all these rampers and pumpers you're talking about?"

Nowhere to be seen, Bermudashorts, but mark my words they will appear if and when AMYT announces exciting news! They always do! It's a fact of life for every speculative AIM share advfn & lse bb.

PS. I think you need to read my post again, Bermudshorts, because I distinstly said they will only arrive on this bb when AMYT announces great news. AMYT is NOT a AIM tiddler with a miniscule Mkt Cap. They are always being ramped by pumpers & dumpers, which is why I would never look at them.

Nobody is "bashing" AMYT apart from Bronxville and radar on the lse bb. There's not "plenty of AMYT bashing". In fact if it wasn't for my posts on this bb it would be almost dead (some probably hope I was dead instead!)! There would be no posts for days on end without me. However wait until good news arrives; then there will be a deluge of posts from posters we have never seen before on this bb.

You say "God help us if the sentiment on these boards is the result of ramping posters.". Rampers on these bb's are a fact of life (as are your "bashers"). We will see plenty of both when (and if) great news is issued. That's a FACT; prepare for it. I will be overjoyed to see the rampers on this bb for it will mean a fantastic RNS has been issued. You might even turn into a ramper yourself! :-)

[bazworth] 30/5/2018 15:28

Just hope if comes good before the Zimmer warranty expires.......

[rathean] 30/5/2018 15:15

It's like the Twilight Zone in here. Every stock on my 40+ watchlist has moved today except... answers on a postcard!

[papillon] 30/5/2018 14:17

Another 100k trade @ 17.26p. lse have it as a buy, but who knows? I certainly don't.

Yes bazworth, JbTs's posts were interesting. Of course a really good news RNS would blow all the charts and all the suppositions of whether a particular trade was a buy, or sell and whether it was delayed, out of the water. A really good news RNS would have the rampers, pumpers & dumpers and momentum traders jumping on the AMYT bandwagon and we would have share price "LIFT OFF"!! Unfortunately yesterday's RNS didn't attract the attention of the said rampers, pumpers & dumpers & momentum traders! More's the pity since I was looking forward to closing my small T20 in a few weeks time for a nice few hundred profit. Ah well, back to reality! It's looking like I'll be lucky to make a few hundred pence rather than a few hundred pounds! :-)

PS. I follow the AMYT chart, but I don't act on it. If I did I would have sold all my AMYT shares over 6 months ago, back in October, when a bearish "Death Cross" appeared on the AMYT chart (a falling 50 day EMA falling below an already falling 200 day EMA). Of course I didn't sell because one always hopes for a really good news RNS to be issued, such as happened back in December 2016 (2 arrived in quick succession) and the bearish AMYT chart was blown out of the water. Unfortunately we are still waiting for that really good news RNS to be issued in 2018.

[papillon] 30/5/2018 12:16

Hi, bazworth. Okay, I'll take him off my filter list.

[bazworth] 29/5/2018 21:30

Hi papillon

I would read JbbT's post, I do think it is worth it!!

Cheers

[papillon] 29/5/2018 21:06

I'm VERY PATIENT, bazworth. I first bought into FAST over 3 years ago in early 2015 when the share price was marginally above 2p. After taking into a/c the 8 for 1 consolidation my initial investment has gone nowhere during that almost 3 and a half years! If that's not being patient I don't know what is! I hope my patience is suitably rewarded.

Whether I'll be "extremely happy" in around 6 months time will depend on the AMYT share price at the end of October/November following on from the EASE interim results. Fingers crossed they are excellent!

PS. I have JimbobTechstock on filter (because he told lies about me) so I can't read his, no doubt, informative posts.

PPS. I didn't buy FAST as an O&G stock. I bought it because it was to all intents and purposes a cash shell (priced at a substantial discount to it's cash) because a few months previously at the end of 2014, Cathal Friel, had talked of either returning the cash to shareholders, or FAST becoming a biotech via an RTO.

[bazworth] 29/5/2018 20:02

I’m extremely happy to hold and be patient!

[jimbobtechstock] 29/5/2018 19:51

Deferral means it was possibly a worked sell from earlier, possibly even for last week if brokers are up to tricks. Nothing like dropping a 16.5p print well below bid at a time when the bid is actually surprising strong, for a change. Could also be some other kind of roll-up.

[jimbobtechstock] 29/5/2018 19:49

I do. I do. It's a deferral, so not a current price for that time. See the new MiFID II trade flags published on the stock exchange.

I think a disproportionate amount of trades here are funny ATM. E.g. The full-ask buy at 13:19 for 2,500 was not a current price at the time. Wasn't on-book so not MM testing each other.

I was actively polling the bid around the time of the 100k so I know for a fact I could sell large amounts (100k+) in one go for above mid (17.26p) and up to 50k for 17.31p, even after the 25k sold for above mid at 4pm.

That itself (trading above mid) is a change here at AMYT, as the trading has for months been pushed into the bottom half of the L2 spread, buys AND sells, thereby marking nearly all trades as sells on sites like LSE, and depressing LTHs no doubt, seeing months of just selling...

Decent day today, but still very quiet share. Not many PIs interested, RNS not marked as popular on VOX, etc. Great time to accumulate IMO.

[papillon] 29/5/2018 17:53

And then just before the close 100k goes through below the 17p bid price @ 16.50p!!

All very baffling; well it baffles an old git like me!! No doubt JimbobTechstock has his theories.

Who is dumping these large amounts of shares, well below the bid price and why? Are they ex FAST shareholders finally fed up with holding a bio? Are they members of the so called "concert party" who bought in the original 24p placing at well below that 24p?

I know we're only small PI's and are supposed to remain ignorant of what is going on, but sometimes it would be great to be given a reason, now and again. Mushrooms like being kept in the dark and fed sh*t, but we're not mushrooms.

[papillon] 29/5/2018 16:14

Buys going through at full asking price of 17.50p. Good sign.