Advanced Oncotherapy Share Discussion Threads

[daijavu] 02/5/2019 11:26

cbd. Why don't you go away and stop cluttering up the boards.

cbd filtered

[daijavu] 17/4/2019 15:03

Cynicism aside, there are issues about when AVO will achieve a revenue and move into profitability. AVO says that the first patient is expected to be treated by the end of 2020. On past showing, that might be overly optimistic because AVO has a track record of failing to meet its promised development targets. Even if that particular target is met, Moataz is just the latest occupant of his job. Even if he is all that is said, he may have an insurmountable task until LIGHT has been shown to work on a patient and AVO has shown that they can deliver LIGHT to their customers in accordance with any agreed timetable. I have my doubts. Even if all goes to plan, there might not be any revenue until around 21/22. AVO may not reach break even until two or thee years later with profitability being achieved a few years after that. That is around ten years down the road before shareholders might expect a return.

imho, it is an investment that requires a lot of patience.

[daijavu] 16/4/2019 23:40

Come come twirl. Don't spoil the newbies' illusions. After all, one day AVO might surprise us all by actually doing what it says on the tin.

I wonder how long it will be before the new crop of wannabee AVO millionaires realise that just because AVO says they are on track, it doesn't mean that they actually are.

[discodave4] 16/4/2019 22:24

Sorry wrong board

[twirl] 16/4/2019 20:54

Lets hope so but at present no one wants to buy it.

Unlike 3 yrs ago when orders were made and the then commercial director appointment bathed in blue sky which turned out to be a mirage.

[baner] 16/4/2019 08:41

an excellent recruitment announced today. we are approaching commercial launching for this potential unicorn company!

[metis20] 22/2/2019 20:33

The below is from

► Strategy: AVO is developing a compact and modular PT system at an affordable price for the payor, financially attractive to the operator, and generating superior patient outcomes. AVO benefits from the technology know-how developed by CERN and ADAM, Geneva, and relies on a base of world-class suppliers.
► ISO approval: ISO 13485 is an internationally agreed standard that sets out the requirements for a quality management system specific to the medical devices industry. It can also be used by internal and external parties, such as certification bodies, to help them with their auditing processes.
► Development update: Infrastructure to support the installation and assembly of the full LIGHT system has already started at STFC’s Daresbury Laboratory. Once the complete system has been installed and validated, it will be used to support AVO’s submission for CE marking, prior to first patients in 2020.
► Risks: With the £10m funding announced in December, AVO is maintaining its ability to meet its objectives and keep the pace of its manufacturing plan. Execution risk remains, but the more complex technical challenges have been overcome, and integration of the remaining units is an easy step towards getting the LIGHT accelerator.
► Investment summary: Demand for PT is increasing worldwide, and the need for a small, flexible, affordable and close-to-patient system is desirable. AVO has attracted strong manufacturing and investment partners, and discussions with potential customers are advancing. Progress at the flagship Harley Street site has been substantial, and installation of the first LIGHT system is planned to start in mid-2019. The latest technical update has brought further assurance and boosted confidence.

The previous Hardman report -

[paul_98] 22/2/2019 18:47

Got a good feeling.

[daijavu] 22/2/2019 17:53

I hope you are right but, in my experience, the BoD do not feel much loyalty to their small private investors.

[paul_98] 22/2/2019 17:15

On the contrary I’m really pleased with how this is firming up. So much progress, so many more positives and a largely derisked investment. Very positive outlook. GLA. Loyalty and patience the key.

[daijavu] 22/2/2019 16:59

The news is pretty meaningless and is in keeping with most of AVO's past hype that crumbled to dust.

Options cost nothing to issue and will only be taken up if the share price actually reaches the exercise price. It might not. AVO might fold and LIGHT might go to another owner at a knockdown price if AVO comes under administration.

I speak with the sad voice of experience of how the BoD has worked in the past. The only development news I trust is the progress on Harley Street. Their past claims about the development of LIGHT have always turned out to be untrue. Light was originally supposed to be fully developed three years ago. I have a copy of the original development schedule. Even now they are behind their most recent published development schedule. The latest completion date passed some time ago but they have not given a new completion date.

I could go into detail about the number of Chinese contracts they have won and lost, the number of Chinese backers who supposedly paid them large sums of money with no discernible outcome and the money they had to repay to Sinophi for breach of contract when LIGHT was far from complete although the BOD said development was on time

I haven't lost faith in LIGHT but will only trust the BoD when they can demonstrate that they are getting a sustainable income from sales.

I am holding onto my money until then.

[makeamillion1] 19/2/2019 22:37

Target Price is £1.55 that is why

[...]

[justjill] 19/2/2019 21:21

Thanks for that Metis. Well as they tend to say.....someone looks interested? Wonder why now though.

[paul_98] 19/2/2019 11:36

Positive signs. Anyone in the know understands this is, and has always been, a waiting game. I’ve got a good feeling.

[makeamillion1] 19/2/2019 10:47

Daijavu, I think you should go back to bed you have had a bad dream and wake up on the other side. GLA This share is way undervalued IMO

[daijavu] 19/2/2019 10:21

LIGHT is licenced to AVO by CERN. CERN is still the owner. Depending on the terms of the licence CERN might be able to block any transfer of ownership to China and might be big enough to be able to sue if China copied it.

[mikecfc77] 19/2/2019 09:43

Tick up, are we expecting some incoming news?

[waterloo01] 06/2/2019 14:08

Any noises here? Harley Street?

I'm somewhat amazed, given the current concerns re tech transfer and theft in China that the $$bn's spent by the EU could just be 'transferred' to China.

One wonders if the EU and CERN will wake up to that at some point and put a stop to it or is it too late?

[daijavu] 20/12/2018 19:22

paul, As I have said before, I share your enthusiasm for the product. but I also believe that AVO remains a risky investment.

They are once again pushing up against the limits of their timetable for the development of LIGHT without any clarity regarding when the development will be completed. The Chinese involvement is also a concern, given the past history of their involvement in AVO, the reputation the Chinese have for copying Western technology and the current geo-political situation. The current instability in the market does not help.

I'm keeping AVO on my watch list and I will wait and see what happens.

[paul_98] 18/12/2018 08:25

Personally I still have absolutely no doubt in this company and the significant progress towards a fantastic product and high reward.

[twirl] 18/12/2018 07:57

Whatever the progress and potential the market is in very unstable conditions and in the event of a market crash the worst hit stocks are likely to be those without revenue.

[metis20] 14/12/2018 11:05

From LSE board 3rd Dec

"Harley Street, the scaffolding is coming down at the front, still plenty to do at the back but progressing well."

and from 10th October RNS -

Work is progressing at Daresbury Laboratory to build and prepare the test facility ready for the installation and assembly of the full LIGHT system from later this year. Some of the components of the LIGHT system have already been delivered onsite. The Science and Technology Facilities Council ("STFC") and AVO are working closely to ensure that the building work is on track to allow the installation of the LIGHT system to start next month in order to be ready for full-energy testing next year.





To date during 2018, AVO has raised ca.£40m of cash from its new commercial partner, Yantai CIPU, and other investors, which has enabled the company to clear all its debts, provide working capital and bring additional stability. Further capital will be required, which could come from a number of sources. However, AVO, on the back of its continuous and successful operational progress, has greater flexibility now with its improved and clean balance sheet.