4d Pharma Share Discussion Threads

[rastamouse] 27/10/2020 23:28

Hope so Stig.200 pounds here we come!!!!Peace out

[thepaddedcell] 27/10/2020 23:26

And the big "what if" moment could be a combination or all 4 shots coming good one after the other ! That would be a game changer !

[the stigologist] 27/10/2020 23:18

No idea what could be our 'breakout' moment as we don't have a Phase III trial 'success' due

However worth noting Seres's 'success' is a 'success' in inverted commas because their trial was 'underpowered' with only c.200 participants and the FDA have refused Seres' request for a meeting to expedite approval. Seres are having to thus recruit more patients and will have to wait for the extended study to complete before they reach commercialisation

Meanwhile we have a chance of reaching commercialisation milestone prior to them possibly in TWO indications

1. Cancer - owing to safety profile, combination with Industry leader Keytruda/Merck, MD Anderson links to FDA etc there is high chance MRx0518 could be approved in 2021 and rapidly commercialised alongside $20bn p.a. Keytruda

2. Covid - again owing to MRx0004 safety profile, given emergency nature of pandemic, IF MRx0004 demonstrates any efficacy it has the chance to be fast-tracked into commercialisation

Other potential BREAKOUT catalysts could be :-

Any Merck Vaccine - milestone payment or even a positive official progress report

Listing on NASDAQ in January 2021 under ticker LBPS

I make it about 4 shots on goal in the next few months which could give us our Seres type breakout moment

[thepaddedcell] 27/10/2020 23:17

Slow and steady wins the race ! Still up around 20% on this time last week.

[master rsi] 27/10/2020 23:15

From the "UPS" thread .....

AAAA 116p

Today's early drop reached 61.8% Fibonacci retracement the normal point of bounce back, and also the 110p merger terms. Time to bounce back to higher points help by the Covid 19 getting worse.

[the stigologist] 27/10/2020 21:53

In Halloween week a bit spooky how our weekly chart is setting up exactly like Seres MCRB prior to their breakout on Phase III data...

The share price towards the bottom of the weekly Moving Average...

[devonlad] 27/10/2020 21:50

Bermudashorts - legend. It feels like a scene from the shining at the moment, scary but you know what is coming.

[the stigologist] 27/10/2020 21:36

We're just days/weeks/months away from deals of this type and/or actual commercial launch and sales into the $200 Billion a year Cancer Therapy market

[the stigologist] 27/10/2020 21:31

The 4th Annual Next-Gen Immuno-Oncology Congress demonstrates how young this huge market is and the exciting development/combination options.

Great to see 4D will be there hob-nobbing with the Leaders in the space (No other microbiome player attending AFAICS)



30+ experts from academia and industry will be presenting their current work in Immuno-Oncology, Latest updates on regulatory guidelines and approvals, Validation markers for tumor-derived T-cell subpopulations, NextGen T-Cell and CAR-T Cell therapy, Personalized Medicine, Biomarkers and Cancer Immunotherapy

[someuwin] 27/10/2020 21:24

Yes - VERY good find.

[ambyth] 27/10/2020 21:18

Great find Bermudashorts!

[bermudashorts] 27/10/2020 21:15

Devonlad

Both Alex Stevenson and Imke Mulder are involved in the January event. Alex Stevenson is on the panel for the European Microbiome Leaders Discussion and Dr Mulder is presenting later in the day - details of her presentation below, last line is interesting:-

MicroRx Single Strain Live-Biotherapeutics: POC Clinical Data and Future Considerations

- From preclinical models to proof of concept in patients
- Next phase of clinical development
- Second generation MicroRx LBPs and new target diseases

[devonlad] 27/10/2020 21:03

January event could be quite interesting.

[the stigologist] 27/10/2020 20:42

Packed schedule in the weeks/months ahead

[lionheart72] 27/10/2020 20:26

so a woke version of Fingerbobs then

[blueblood] 27/10/2020 20:21

The vermin needs to be removed

[showmethemoneyhoney01] 27/10/2020 20:13

Rastamouse is a British animated stop motion children's TV series created by Genevieve Webster and Michael De Souza and produced by Three Stones Media/The Rastamouse Company for CBeebies. The show follows crime busting mouse reggae band Da Easy Crew, who split their time between making music and solving mysteries for Da President of Mouseland..........say no more!

[rastamouse] 27/10/2020 19:54

50 Day MA at around 1.22Hopefully it should test that and climb above soon.If it does then 1.80 is on again.If not the 1.00 could be tested.

[rastamouse] 27/10/2020 19:51

https://twitter.com/Share_Talk/status/1321123343211372546?s=20

[hazydaisy] 27/10/2020 19:17

At present, numerous trials are exploring how to manipulate the gut microbiota in an effort to improve clinical outcomes. Several methods are currently being investigated, including the use of prebiotics, probiotics, fecal microbiota transplantation, or capsules loaded with bacteria.

One clinical trial (ClinicalTrials.gov identifier NCT03934827) is actively recruiting multiple solid tumors to investigate a novel biotherapeutic, MRx0518, which is composed of a proprietary strain of bacterium. Patients who have been diagnosed with one of many solid tumors and are amenable to surgical resection are eligible for this study.

[gooner1886] 27/10/2020 19:07

Lol Maybe tomorrow you will have a clearerHead

[rastamouse] 27/10/2020 19:03

Lol.What u do with your boyfriend should be between you and your boyfriend.Peace out

[rastamouse] 27/10/2020 18:12

Nothing underpins nothing