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4BB 4basebio Plc

1,035.00
0.00 (0.00%)
18 Apr 2024 - Closed
Delayed by 15 minutes
Share Name Share Symbol Market Type Share ISIN Share Description
4basebio Plc LSE:4BB London Ordinary Share GB00BMCLYF79 ORD EUR1.00
  Price Change % Change Share Price Bid Price Offer Price High Price Low Price Open Price Shares Traded Last Trade
  0.00 0.00% 1,035.00 1,000.00 1,070.00 1,035.00 1,035.00 1,035.00 2,421 01:00:00
Industry Sector Turnover Profit EPS - Basic PE Ratio Market Cap
Pharmaceutical Preparations 335k -5.15M -0.4180 -24.76 127.51M

4basebio Plc Half-year Report

30/09/2021 7:00am

UK Regulatory


 
TIDM4BB 
 
4basebio PLC 
                  ("4basebio", the "Company" or the "Group") 
 
               Half-yearly for the six months ended 30 June 2021 
 
4basebio PLC (AIM: 4BB) (formerly 4basebio UK Societas), the specialist life 
sciences group focused on exploiting intellectual property in the field of cell 
and gene therapies and DNA vaccines, announces its unaudited half-yearly 
results for the six months ended 30 June 2021. 
 
Operational Highlights (including post period end) 
 
  * Conversion to PLC status following approval at the Annual General Meeting 
  * DNA manufacturing facility expected to be completed by year end 
  * Positive validation studies on use of 4basebio synthetic DNA versus plasmid 
    DNA 
  * Multiple patent filings across DNA synthesis and nanoparticle delivery 
    technology 
  * Evaluation and collaboration licence agreements signed with Royal Holloway 
 
Financial Highlights 
 
  * Cash balances of £12.1 million at period end 
  * Cash runway into 2023 before calling on available debt facility 
  * Loss for the period of £1.7 million (H1 2020 loss:  £0.38 million) 
  * Net cash outflow from operating activities of £1.7 million  (H1 2020: £0.51 
    million ) 
 
Commenting on the interim results, Dr. Heikki Lanckriet, CEO and CSO, said "We 
are extremely pleased with the progress achieved during the first half of 
2021.  In particular, we are increasingly confident that during the course of 
2022 we will be able to manufacture meaningful quantities of DNA for resale. 
Initially this will be for research and pre-clinical purposes while we look to 
secure GMP approvals for our manufacturing suites.  We are also very pleased to 
confirm that as expected, we intend to be completing those manufacturing suites 
by the end of 2021. 
 
As we move towards manufacturing capacity, our aim is to work with prospective 
customers to highlight the benefits of our technologies.  We remain very 
positive about the commercial prospects of both our synthetic DNA and non-viral 
vector technology across a range of applications." 
 
For further enquiries, please contact: 
 
4basebio PLC                                             +44 (0)12 2396 7943 
 
Heikki Lanckriet, CEO and CSO 
 
Cairn Financial Advisers LLP (Nominated                  +44 (0)20 7213 0880 
Adviser) 
 
Jo Turner / Sandy Jamieson 
 
finnCap Ltd (Broker) 
 
Geoff Nash/Richard Chambers/Charlotte                    +44 (0)20 7220 0500 
Sutcliffe 
 
Notes to Editors 
 
4basebio (AIM: 4BB) is a specialist life sciences group focused on therapeutic 
DNA for cell and gene therapies and DNA vaccines and providing solutions for 
effective and safe delivery of these DNA based products to patients. It is the 
intention of the Company to become a market leader in the manufacture and 
supply of high purity, synthetic DNA for research, therapeutic and 
pharmacological use and develop non-viral vectors for the efficient delivery of 
payloads. The immediate objectives of 4bb are to validate and scale its DNA 
synthesis and advance its collaborations to facilitate the functional 
validation of its DNA based products and cell and gene delivery solutions. 
 
Chairman's Statement 
 
Introduction 
 
Following shareholder approval of the Annual General Meeting held on 30 June 
2021, the Company subsequently completed its conversion to a PLC from a UK 
Societas upon its registration at Companies House on 20 July 2021. 
 
The Board is pleased to report that 4basebio continues to make good progress 
during the first half of the year in validating and commercialising 4basebio 
DNA and nanoparticle delivery technology.  The Group has established strong R&D 
groups in both the UK and Spain which have been able to focus on improving and 
scaling processes surrounding its synthetic DNA manufacture as well as also 
strengthening its intellectual property, with patent filings across its 
portfolio. 
 
4basebio has also made excellent progress in validating its DNA, being able to 
demonstrate strong performance of its synthetic DNA in comparison with plasmid 
DNA through a number of programmes. 
 
Also as previously noted, it remains our intention to have DNA manufacturing in 
place by the end of 2021 with a view to commencing sale of DNA during 2022.  We 
remain firmly on track to achieve these objectives.  We also continue to 
explore further commercial applications for our DNA and nanoparticles as 
outlined below. 
 
Operational Review 
 
As we reported in our 2020 Annual Report, the Group remains pre-revenue and it 
is focussed on the development of its DNA synthesis and non-viral vector 
technology.  Both technologies have broad application in gene and cell therapy 
as well as vaccines.  We see particular opportunities opening up in AAVs 
(adeno-associated viral vectors) for gene therapy and in-vitro transcription 
(IVT) for the production of mRNA vaccines. 
 
With the objective of reaching commercial DNA manufacturing as swiftly as 
possible, the decision was made during H1 to develop both AAV and mRNA research 
laboratories within our Cambridge facility for the purpose of optimising DNA 
constructs for use in these applications.  Both labs are now operational with 
recruitment ongoing and with the near-term objective of being able to place our 
DNA products into the hands of prospective customers for testing within their 
own AAV and mRNA systems. 
 
During the second half of 2021 the product and technology application focus is 
expanding to include gene editing and cell therapy based applications with the 
recruitment of relevant expertise underway. 
 
Alongside the focus on construct optimisation and application research, there 
is continued development work on the upscaling of DNA production for commercial 
sale.  With this objective central in our thinking, we have commenced work on 
our pilot 4,400 square foot clean room installation; and we expect this to be 
complete by the end of 2021.  This will provide for seven DNA synthesis suites. 
The facility will then undergo testing and validation with a view to becoming 
operational during Q1 2022 and with the intention of manufacturing research and 
pre-clinical grade DNA while working to secure GMP accreditation during the 
remainder of 2022. 
 
The earmarked capital commitment for this project is about £1.5 million. When 
fully operational, the theoretical production capacity of this facility, at 
prevailing market prices is expected to exceed £25 million per annum. 
 
Following consideration of the overall resource requirements for the DNA and 
nanoparticle sides of the business, it has been decided to expand research 
laboratory space within the existing Cambridge facility.  As a result, the 
clean room installation will be located in a separate facility also near 
Cambridge and four miles from head office. (The Company has secured a lease 
over this site for a period of 15 years, with suitable break clauses.) The 
manufacturing suites and associated quality management systems will be operated 
by a dedicated team, which will work independently in this standalone 
production facility. 
 
A key consideration in executing on our strategy is the ability to recruit 
appropriately skilled team members.  The Group is competing for candidates in a 
rapidly growing market segment but despite these challenges, 4basebio has 
continued growing its teams, with Group headcount expected to be about 35-40 
FTEs by year end. 
 
Alongside these developments, the Group continues to file patent applications 
relating to further innovation around hpDNAT, osDNAT and HermesT 
nanoparticles.  We have filed our first two applications protecting the use of 
HermesT nanoparticles for specific applications as well as additional filings 
protecting hpDNAT and osDNAT manufacturing processes and uses.  We believe 
continued investment in intellectual property is a cornerstone of enhancing the 
value of the Group's technology. 
 
As noted earlier, 4basebio also continues to progress its collaboration 
projects including its project with Royal Holloway focussed on Duchenne 
muscular dystrophy, with 4basebio screening for an optimised delivery vector. 
Whilst the overall project is expected to run for two years; we are pleased to 
note that certain aspects are progressing more quickly than originally 
planned.  In particular, 4basebio has made very good progress in in-vitro 
models in identifying nanoparticles with strong affinity for muscle cells; and 
we are now progressing to in-vivo models to validate and optimise these 
particles. 
 
Coronavirus 
 
The impact of COVID-19 on operations has been very modest.  The Group continues 
to adhere to local COVID protocols in the UK and Spain. 
 
Business outlook 
 
The Group expects to continue investing in its technologies and team members 
during 2021 and 2022.  Modest non-core revenues are expected at levels 
consistent with previous periods; ongoing expenditure will continue to be much 
greater than revenues, with the Group consequently recording a loss for the 
year.  This is as previously indicated. 
 
During the latter half of the year, 4basebio expects to make several further 
patent filings and continue with its range of research and development 
projects, both internally and with collaborators.  The Group also expects to 
have concluded the physical build out of its clean rooms by the end of 2021, 
with GMP certification being sought during the course of 2022. 
 
Financial Review 
 
Comparative information 
 
As explained in note 2 to the interim results, the prior period comparatives 
for the period ended 30 June  2020 reflect solely the financial performance and 
position of 4basebio S.L.U.  The results for period ended 31 December 2020 
include 4basebio PLC and 4basebio S.L.U. for the whole year and 4basebio PLC's 
UK subsidiaries from the date of the spin out, 8 December 2020.  The 
consolidated balance sheet as at 31 December 2020 includes 4basebio PLC and all 
subsidiary companies. 
 
The results for the period ended 30 June 2021 and the consolidated balance 
sheet at that date reflect the consolidated performance and position of 
4basebio PLC and all its subsidiary companies 
 
Revenue 
 
Revenue in the first six months of 2021 ("H1 2021") was £0.18 million (H1 2020: 
£0.16 million ).  Consistent with previous periods, this reflects legacy 
revenue streams including kits sales and licence income. 
 
Cost of sales 
 
Cost of sales in H1 2021 was £38k (H1 2020:  £86k).  As noted in the 2020 
Annual Report, cost of sales reflects primarily the amortisation on previously 
capitalised intangible assets linked to kit sales. 
 
Selling and administration expenses 
 
Selling, general and administrative expenses were a combined £1.2 million in H1 
2021 (H1 2020: £0.24 million ). Prior period expenses reflect the expenditure 
in 4basebio S.L.U. only, while the current period includes the now 
significantly larger UK operations. 
 
Research and development 
 
Overall research and development expenditure for H1 2021 was £0.86 million (H1 
2020: £0.28 million ), of which £0.23 million was capitalised in the period (H1 
2020: £0.14 million ).  Overall expenditure increased due to the expansion of 
the UK team which commenced late 2020 and remains ongoing.  Capitalised 
expenditure relates to platform research undertaken in Spain. 
 
Tax 
 
Tax represents R&D tax credits expected to be recovered in relation to 
expenditure during the first half of the year. 
 
Balance sheet 
 
Non-current assets increased to £2.5 million at 30 June 2021 from £2.3 million 
at 31 December 2020; this related to fixed asset additions in the UK.   Current 
assets fell to £12.8 million at 30 June 2021 from £15.5 million at 31 December 
2020, due primarily to cash outflows during the first half of 2021.  As a 
result, closing cash balances at 30 June 2021 stood at £12.1 million (31 
December 2020: £15 million). 
 
Current liabilities decreased to £0.64 million at 30 June 2021 from £0.83 
million at 31 December 2020 due to the repayment of softloans in the first part 
of the year.    Long term financial liabilities reduced due to reclassification 
of softloans from long term to short term liabilities.  As a result, overall 
long term liabilities stood at £1.3 million as at 30 June 2021 (31 December 
2020: £1.5 million). Other long term liabilities represent deferred grant 
income in Spain. 
 
Share Capital at both 30 June 2021 and 31 December 2020 reflects the capital 
contributions arising from the spin out process as explained in the Annual 
Report for 2020 and note 2 to the interim results. 
 
Cash flow 
 
Net cash outflows from operations were £1.7 million for the six months ended 30 
June 2021 (period ended 30 June 2020: outflow of £0.53 million ).  This 
reflects the step change in operations between the periods as presented in the 
profit and loss account; in particular the upscaling of UK operations. 
Operating cash outflows for the current period also include £360 thousand 
relating to the AIM listing in February 2021. 
 
Cash outflows from investing reflect planned investments in capital expenditure 
across the group and capitalised development expenditure in 4basebio S.L.U.. 
 
Cashflows from financing for the period ended 30 June 2021 reflect Spanish 
softloan repayments, while the prior period shows net cash inflows from the 
then parent 4basebio AG (now 2Invest AG).  The large cash inflow for the year 
ended 31 December 2020 reflects the spin out process accounting as explained in 
the 2020 Annual Report. 
 
Exchange differences for the period represent changes in the British pound 
value of cash balances held in foreign currency, almost entirely euro 
denominated. 
 
Tim McCarthy 
Chairman 
30 September 2021 
 
Consolidated statement of profit or loss and other comprehensive income 
for the six months ended 30 June 2021 
 
[in £'000]                                    Note      Six months    Six months  Year ended 
                                                          ended 30 ended 30 June   31 December 
                                                         June 2021          2020          2020 
                                                       (unaudited)   (unaudited)     (audited) 
                                                          (note 2)      (note 2)      (note 2) 
 
Revenues                                        4              179           159           462 
 
Cost of goods sold                                            (38)          (86)         (188) 
 
Gross profit                                                   141            73           274 
 
Sales and marketing expenses                                  (81)          (79)         (141) 
 
Administration expenses                                    (1,155)         (163)         (516) 
 
Research and non-capitalised development                     (633)         (138)         (343) 
expenses 
 
Other operating expenses                                     (103)          (78)           (1) 
 
Other operating income                                          15            15           105 
 
Loss from operations                                       (1,816)         (370)         (622) 
 
Finance expense                                               (31)          (11)          (94) 
 
Loss before tax                                            (1,847)         (381)         (716) 
 
Income tax credit / expense                     5              197             -           (3) 
 
Loss for the period                                        (1,650)         (381)         (719) 
 
    Loss per share                              6 
 
      * Diluted and Undiluted (in £/share)                  (0.13)        (0.05)        (0.08) 
 
Items that may be reclassified to the 
income statement in subsequent periods 
 
    Exchange rate adjustments                                (393)          (11)           162 
 
Total comprehensive income                                 (2,043)         (392)         (557) 
 
 
All of the loss for each period is from continuing operations. 
 
Consolidated statement of financial position 
  30 June 2021 
 
[in £                                       Note         30 June 31 December 
'000]                                                       2021        2020 
                                                     (unaudited)   (audited) 
                                                        (note 2)    (note 2) 
 
Assets 
 
Intangible assets                             7              937         785 
 
Property, plant and equipment                 8            1,501       1,478 
 
Other non-current assets                                      32          34 
 
Non-current assets                                         2,470       2,297 
 
Inventories                                                  101         131 
 
Trade receivables                                            120          39 
 
Other current assets                                         551         341 
 
Cash and cash equivalents                     9           12,064      15,001 
 
Current assets                                            12,836      15,512 
 
Total assets                                              15,306      17,809 
 
Liabilities 
 
Financial liabilities                                      (223)       (416) 
 
Trade payables                                             (150)        (96) 
 
Other current liabilities                                  (241)       (301) 
 
Current liabilities                                        (614)       (813) 
 
Financial liabilities                                    (1,051)     (1,301) 
 
Other liabilities                                          (226)       (237) 
 
Non-current liabilities                                  (1,277)     (1,538) 
 
Total liabilities                                        (1,891)     (2,351) 
 
Net assets                                                13,415      15,458 
 
Share capital                                             11,130      11,130 
 
Share premium                                                706         706 
 
Merger reserve                                               688         688 
 
Capital reserve                                           13,099      13,099 
 
Foreign exchange reserve                                   (218)         175 
 
Share based payments reserve                                (35)           - 
 
Profit and loss reserve                                 (11,955)    (10,340) 
 
Total Equity                                 10           13,415      15,458 
 
 
Consolidated statement of changes in equity 
for the six months ended 30 June 2021 
 
[in £'000]                                Share Share premium       Merger      Capital       Foreign  Share based  Profit and  Total equity 
                                        capital                    reserve      reserve      exchange     payments        loss 
                                                                                                                       reserve 
 
Balance at 1 January 2020 (audited)       6,362             -            -        1,356            13            -     (9,621)       (1,890) 
 
Capital contributions from 4basebio           -             -            -       11,743             -            -           -        11,743 
AG (now 2Invest AG) 
 
Combination accounting                  (6,258)             -          688            -             -            -           -       (5,570) 
 
Loss after income tax                         -             -            -            -             -            -       (719)         (719) 
 
Shares issued for cash                    3,209           706            -            -             -            -           -         3,915 
 
Foreign Exchange difference arising           -             -            -            -           162            -           -           162 
on translation of 4basebio S.L.U. 
 
Shares issued to acquire                  7,817             -            -            -             -            -           -         7,817 
subsidiaries 
 
Balance at 31 December 2020              11,130           706          688       13,099           175            -    (10,340)        15,458 
(audited) 
 
[in £'000]                                Share Share premium       Merger      Capital       Foreign  Share based  Profit and  Total equity 
                                        capital                    reserve      reserve      exchange     payments        loss 
                                                                                                                       reserve 
 
Balance at 1 January 2021 (audited)      11,130           706          688       13,099           175            -    (10,340)        15,458 
 
Loss after income tax and total               -             -            -            -             -            -     (1,650)       (1,650) 
comprehensive income for the period 
 
Share option charge                           -                                       -                       (35)          35             - 
 
Foreign Exchange difference arising           -             -            -            -         (393)            -           -         (393) 
on translation of 4basebio S.L.U. 
 
Balance at 30 June 2021 (unaudited)                                      688`        13,099         (218)     (35)      (11,955)      13,415 
                                       11,130     706 
 
 
Consolidated statement of cash flows 
  for the six months ended 30 June 2021 
 
[in £'000]                                                   30 June       30 June 31 December 
                                                                2021          2020        2020 
                                                         (unaudited)   (unaudited)   (audited) 
                                                            (note 2)      (note 2)    (note 2) 
 
Net loss for the period                                      (1,650)         (381)       (719) 
 
Adjustments to reconcile net loss for the period to 
net cashflows 
 
Income taxes                                                   (197)             -           3 
 
Interest charge                                                   31             3          94 
 
Depreciation of property, plant and equipment                    106            30          83 
 
Amortisation and impairment of intangible assets                  41            87         194 
 
Other non-cash items                                              52            12          25 
 
Working capital changes: 
 
    Trade receivables and other current assets                  (99)          (34)          91 
 
    Trade payables and other current                              24         (138)       (876) 
    liabilities 
 
    Inventories                                                   26          (92)        (24) 
 
Tax receipt                                                        -             -         107 
 
Net Cash flows from operating                                (1,666)         (513)     (1,022) 
activities 
 
Investments in property, plant and equipment and               (141)         (126)       (351) 
intangible assets 
 
Investments in capitalised development                         (231)         (142)       (498) 
 
Cash acquired with 4basebio Limited (now 4basebio                  -             -       2,295 
UK Limited) 
 
Cash flows from investing activities                           (372)         (268)       1,446 
 
Cash in(out)flow due to changes in financing                   (337)         1,244     (1,024) 
 
Capital contributions by way of cash                               -             -      15,626 
 
Interest paid                                                   (31)           (3)       (116) 
 
IFRS16 leases                                                   (64)          (18)        (59) 
 
Cash flows from financing activities                           (432)         1,223      14,427 
 
Net change in cash and cash equivalents                      (2,470)           442      14,851 
 
Exchange differences                                           (467)            22          70 
 
Cash and cash equivalents at the beginning of the             15,001            80          80 
period 
 
Cash and cash equivalents at the end of the period            12,064           544      15,001 
 
 
Notes to the financial statements 
For the six months ended 30 June 2021 
 
1.General information 
 
4basebio PLC, formerly known as 4basebio UK Societas, is registered in England 
and Wales as a public limited company since 20 July 2021. Prior to that date it 
was registered as a United Kingdom Societas under the name 4basebio UK 
Societas. The conversion to a public limited company occurred following 
shareholder approval of the conversion at its Annual General Meeting held on 30 
June 2021.  With the conversion, the name of the Company changed to 4basebio 
PLC. 
 
The Company is domiciled in England and the registered office of the Company is 
25 Norman Way, Over, Cambridge, CB24 5QE.  4basebio PLC is the parent of a 
group of companies.  The group structure remains the same as that shown in the 
Company's financial statements for the year ended 31 December 2020.  The Group 
focusses on life sciences and in particular the development of synthetic DNA 
and nanoparticles suitable for inclusion in, or delivery of, therapeutic 
payloads for cell or gene therapies and gene vaccines. 
 
The interim report was approved by the board of directors on 29 September 2021. 
 
The Company trades on London Stock Exchange's AIM market, having been admitted 
on 17 February 2021.  The international securities number (ISIN) number for its 
AIM traded shares changed on 29 July 2021 to GB00BLD8ZL39 reflecting the 
conversion to a PLC; its ticker symbol is 4bb.l. 
 
2.Significant accounting policies 
 
Basis of preparation 
 
As set out in the Company's annual report and financial statements for the year 
ended 31 December 2020, the directors considered the circumstances giving rise 
to the formation of the Group and relevant guidance in IFRS 3.B13 to IFRS 
3.B17, and concluded that the combination, on 8 December 2020, in which the 
Company issued 8,622,231 shares to the shareholders of its former parent entity 
as consideration for the spin-off assets comprising shareholdings in 4basebio 
S.L.U. and 4basebio Limited (now 4basebio U.K. Limited), should be treated as a 
continuation of 4basebio S.L.U. at historic book values for the purposes of the 
Company's statutory financial statements. 
 
Therefore, this consolidated interim financial information for the six months 
ended 30 June 2021 is in substance the continuation of the financial 
information of 4basebio S.L.U. The consolidated financial information for the 
six months ended 30 June 2021 comprises the results of 4basebio S.L.U., 
4basebio UK Limited, 4basebio Discovery Limited and 4basebio PLC for the full 
period presented. The financial information for the comparative period ended 30 
June 2020 precedes the date of the combination and, consequently, reflects the 
results and position of 4basebio S.L.U.  This financial information does not 
constitute statutory accounts but has been prepared under IFRS and in 
accordance with the group accounting policies disclosed in the Company's 
statutory financial statements for the year ended 31 December 2020, as well as 
the share based payments accounting policy described below. 
 
Share based payments 
 
Where share options are awarded to employees, the fair value of the options at 
the date of grant is charged to the Statement of Comprehensive Income over the 
vesting period. The fair value is measured at the date of grant and spread over 
the period during which the employees become unconditionally entitled to the 
options. The fair value of options granted under the share option schemes is 
measured using a probability adjusted Black Scholes model.  Non-market vesting 
conditions are taken into account by adjusting the number of equity instruments 
expected to vest at each reporting date so that, ultimately, the cumulative 
amount recognised over the vesting period is based on the number of options 
that eventually vest. The estimated probability of market vesting conditions is 
factored into the fair value of the options granted. Where the terms and 
conditions of options are modified before they vest, the increase in the fair 
value of the options, measured immediately before and after the modification, 
is also charged to the Statement of Comprehensive Income over the remaining 
vesting period. 
 
Significant judgments 
 
The significant judgments made in relation to the financial statements are 
further set out below. 
 
Going concern 
 
The directors have, at the time of approving the interim report, a reasonable 
expectation that the Group has adequate resources to continue in operational 
existence for the foreseeable future. Thus, they continue to adopt the going 
concern basis of accounting in preparing the financial statements. 
 
Internally?generated intangible assets - research and development expenditure 
 
Development expenditure is capitalised when the conditions referred to in Note 
2 of the Company's 2020 annual report are met. Estimates and underlying 
assumptions are reviewed on an ongoing basis. Revisions to accounting estimates 
are recognised in the period in which the estimate is revised if the revision 
affects only that period or in the period of the revision and future periods if 
the revision affects both current and future periods. 
 
3.Foreign currencies 
 
The functional currency of the Group is British Pounds. 
 
The principal currency rate of the Group other than the British Pounds is the 
euro which has developed as follows in relation to the equivalent of one pound 
(GBP/£): 
 
[in GBP]              Closing exchange rate                Average exchange rate 
 
                30.06.2021 31.12.2020                  Six months Six months 
                                                         ended      ended     Year ended 
                                                       30.06.2021 30.06.2020  31.12.2020 
 
Euro                         0.9089                      0.8678     0.8740      0.8895 
                0.8581 
 
 
4.Revenues 
 
Revenue by type                               Six months Six months 
[in £'000]                                         ended      ended Year ended 
                                              30.06.2021 30.06.2020 31.12.2020 
 
Revenue from sales of kits and other products        168        137        428 
 
Revenue from licences and royalties                   11         22         34 
 
Total revenue                                        179        159        462 
 
 
 
Geographic markets                             Six months   Six months 
[in £'000]                                          ended        ended   Year ended 
                                               30.06.2021   30.06.2020   31.12.2020 
 
Europe                                                  59        74          115 
 
USA                                                    120        85          347 
 
Total revenue                                          179       159          462 
 
 
5.Income taxes 
 
The Group anticipates claiming R&D tax credits in both the UK and Spain in 
relation to the year ended 31 December 2021.  The quantum of such claims for 
the first half of the year is estimated at £197 thousand. 
 
The tax loss carry forwards for which no deferred tax assets were recognised 
across the Group amounted to approximately £10.8 million (31 December 2020: £ 
10.0 million). 
 
6.Loss per share 
 
                                                 Six months Six months Year ended 
                                                      ended      ended 31.12.2020 
                                                 30.06.2021 30.06.2020 
 
Numerator [in £'000] 
 
Result for the period                               (1,650)      (381)      (719) 
 
Denominator [number of shares] 
 
Weighted average number of registered shares in 
circulation (ordinary shares) for calculating    12,317,473  7,488,854  9,197,913 
the undiluted earnings per share 
 
Diluted and Undiluted earnings per share             (0.13)     (0.05)     (0.08) 
 
7.Intangible assets 
 
[in £'000]                Development    Licences       Total 
                                costs 
 
Cost or acquisition 
value 
 
01.01.2020                      1,434          86       1,520 
 
Additions                         463          35         498 
 
Disposals                           -           -           - 
 
Exchange differences               90           7          97 
 
31.12.2020                      1,987         128       2,115 
 
01.01.2021                      1,987         128       2,115 
 
Additions                         227           4         231 
 
Disposals                           -           -           - 
 
Exchange differences             (94)         (8)       (102) 
 
31.12.2021                      2,120         124       2,244 
 
Cumulative amortisation 
and impairment 
 
01.01.2020                     1,052           18       1,070 
 
Amortisation                     188            6         194 
 
Disposals                         -             -           - 
 
Exchange differences              64            2          66 
 
31.12.2020                     1,304           26       1,330 
 
01.01.2021                     1,304           26       1,330 
 
Amortisation                      39            2          41 
 
Disposals                          -            -           - 
 
Exchange differences            (63)          (1)        (64) 
 
30.06.2021                     1,280           27       1,307 
 
Net book value 
 
31.12.2020                        683         102         785 
 
30.06.2021                        840          97         937 
 
 
8.Property, plant and equipment 
 
[in £'000]                  Operating    Land and       Usage       Total 
                            equipment   buildings rights from 
                                                       leases 
 
Cost or acquisition 
value 
 
01.01.2020                        243           -          75         318 
 
Additions                         187           -         163         350 
 
Acquisition of                    152         997           -       1,149 
subsidiary 
 
Disposals                           -           -        (79)        (79) 
 
Exchange differences               16           -           6          22 
 
31.12.2020                        598         997         165       1,760 
 
01.01.2021                        598         997         165       1,760 
 
Additions                         141           -           -         141 
 
Disposals                           -           -           -           - 
 
Exchange differences             (17)           -         (8)        (25) 
 
30.06.2021                        721         997         158       1,876 
 
Cumulative amortisation 
and impairment 
 
01.01.2020                        209           -          32         241 
 
Depreciation                       31           5          46          82 
 
Disposals                         (3)           -        (51)        (54) 
 
Exchange differences               12           -           1          13 
 
31.12.2021                        249           5          28         282 
 
01.01.2021                        249           5          28         282 
 
Depreciation                       50          23          33         106 
 
Disposals                           -           -           -           - 
 
Exchange differences             (11)           -         (2)        (13) 
 
30.06.2021                        288          28          59         375 
 
Net book value 
 
31.12.2020                        349         992         137       1,478 
 
30.06.2021                        433         969          99       1,501 
 
9.Cash and cash equivalents 
 
[in £'000]                                     30.06.2021 31.12.2020 
 
Bank balances and cash in hand                     12,064     15,001 
 
Cash and cash equivalents                          12,064     15,001 
 
10.Equity 
 
The share capital of 4basebio PLC as of 30 June 2021 and 31 December 2020 
amounts to a total of ?12,317,473 divided into 12,317,473.  These are all 
registered ordinary shares. There are no shares with special rights or other 
restrictions on voting rights. 
 
Share-based payments 
 
During the period, 542,000 options to subscribe for shares in the Company were 
granted to employees with an exercise price of £1.18 per share and a further 
42,500 options to subscribe for shares in the Company were granted to employees 
with an exercise price of £3.65 per share. 
 
The options vest partially on grant and then periodically over four years, 
subject to market and non-market facing performance conditions.  A share-based 
payments charge is recognised as an expense in the profit or loss over the 
vesting period, taking account of the estimated number of shares that will vest 
and the probability of achieving market facing vesting conditions. The fair 
value of awards granted in the period was measured at the date of grant using a 
probability adjusted Black-Scholes option pricing model. Non-market vesting 
conditions are taken into account by adjusting the number of equity instruments 
expected to vest at each reporting date so that, ultimately, the cumulative 
amount recognised over the vesting period is based on the number of options 
that eventually vest. The estimated probability of market vesting conditions 
being met is factored into the fair value of the options granted. 
 
A share-based payments charge of £35,000 has been expensed in the period with a 
corresponding amount recognised in equity based on fair values of between £0.23 
and £1.44 per option, as at the dates of grant. 
 
11.Events after the reporting period 
 
Conversion to public limited company 
 
On 20 July 2021 the Company was formally converted from a UK Societas to a 
public limited company, following the approval of shareholders at the Annual 
General Meeting of 30 June 2021. 
 
 
 
END 
 
 

(END) Dow Jones Newswires

September 30, 2021 02:00 ET (06:00 GMT)

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