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Merck and Co Inc NYSE:MRK NYSE Common Stock
  Price Change % Change Share Price High Price Low Price Open Price Shares Traded Last Trade
  -0.16 -0.2% 78.25 79.18 78.16 79.04 10,437,137 23:34:13

Alkermes in Trial, Supply Agreement With Merck for Ovarian Cancer Treatment

07/04/2021 1:01pm

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By Chris Wack

 

Alkermes PLC said Wednesday it has entered into a clinical trial collaboration and supply agreement with Merck & Co. to evaluate nemvaleukin alfa in combination with Keytruda in comparison with investigator choice chemotherapy in patients with platinum-resistant ovarian cancer.

Under the terms of the agreement, Alkermes is responsible for conducting the Phase 3 study, which is planned to begin in the second half of 2021.

Nemvaleukin is Alkermes's novel investigational engineered interleukin-2 variant for immunotherapy.

Alkermes said nemvaleukin in combination with Keytruda has demonstrated antitumor activity in heavily pre-treated patients with platinum-resistant ovarian cancer in an ongoing study, with durable and deepening responses observed.

Alkermes shares were up 5% to $20.10 in premarket trading.

 

Write to Chris Wack at chris.wack@wsj.com

 

(END) Dow Jones Newswires

April 07, 2021 07:46 ET (11:46 GMT)

Copyright (c) 2021 Dow Jones & Company, Inc.

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