Form 6-K - Report of foreign issuer [Rules 13a-16 and 15d-16]

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Name	Symbol	Market	Type
Legend Biotech Corporation	NASDAQ:LEGN	NASDAQ	Depository Receipt

	Price Change	% Change	Price	Bid Price	Offer Price	High Price	Low Price	Open Price	Traded	Last Trade
	-1.06	-2.46%	42.07	41.55	42.99	43.53	42.07	43.255	452,813	22:00:00

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

________________________________

FORM 6-K

________________________________

Report of Foreign Private Issuer

Pursuant to Rule 13a-16 or 15d-16

of the Securities Exchange Act of 1934

Date of Report: August 9, 2024

Commission File Number: 001-39307

________________________________

Legend Biotech Corporation

(Exact Name of Registrant as Specified in its Charter)

________________________________

2101 Cottontail Lane

Somerset, New Jersey 08873

(Address of principal executive office)

________________________________

Indicate by check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form 40-F:

Form 20-F x Form 40-F o

Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(1): o

Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(7): o

Legend Biotech Reports Financial Results for the Six Months Ended June 30, 2024

Legend Biotech Corporation (“Legend Biotech”) is furnishing this report on Form 6-K to provide its unaudited interim condensed consolidated financial statements as of June 30, 2024 and for the six months ended June 30, 2024 and 2023 and to provide Management’s Discussion and Analysis of Financial Condition and Results of Operations with respect to such financial statements. In addition, Legend Biotech is updating its pipeline of product candidates, as set forth in Exhibit 99.4 to this Form 6-K.

On August 9, 2024, Legend Biotech issued a press release regarding its unaudited financial results for the six months ended June 30, 2024 and recent business highlights, which is attached to this Form 6-K as Exhibit 99.1. The unaudited condensed consolidated financial statements as of June 30, 2024 and for the six months ended June 30, 2024 and 2023 are attached to this Form 6-K as Exhibit 99.2. Management’s Discussion and Analysis of Financial Condition and Results of Operations is attached to this Form 6-K as Exhibit 99.3.

This report on Form 6-K, including Exhibits 99.1 (other than the information included under “Webcast/Conference Call Details” and “About Legend Biotech”), 99.2, 99.3 and 99.4, are hereby incorporated by reference into Legend Biotech’s Registration Statements on Form F-3 (Registration Nos. 333-278050, 333-257625 and 333-272222) and Legend Biotech’s Registration Statement on Form S-8 (Registration No. 333-239478).

EXHIBIT INDEX


Exhibit						Title
99.1						Press Release, dated August 9, 2024.
99.2						Unaudited Interim Condensed Consolidated Financial Statements as of June 30, 2024, and for the six months ended June 30, 2024, and 2023.
99.3						Management’s Discussion and Analysis of Financial Condition and Results of Operations.
99.4						Pipeline
101						The following materials from Legend Biotech’s Report on Form 6-K for the six months ended June 30, 2024 formatted in XBRL (eXtensible Business Reporting Language): (i) the Unaudited Interim Condensed Consolidated Statements of Profit or Loss and Other Comprehensive Income, (ii) the Unaudited Interim Condensed Consolidated Statement of Financial Position, (iii) the Unaudited Interim Condensed Consolidated Statements of Changes in Equity, (iv) the Unaudited Interim Condensed Consolidated Statements of Cash Flows, and (v) Notes to the Unaudited Interim Condensed Consolidated Financial Statements.

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.


			LEGEND BIOTECH CORPORATION

August 9, 2024			/s/ Ying Huang
			Ying Huang, Ph.D.
			Chief Executive Officer

Exhibit 99.2

LEGEND BIOTECH CORPORATION

UNAUDITED INTERIM CONDENSED CONSOLIDATED STATEMENTS OF PROFIT OR LOSS AND OTHER COMPREHENSIVE INCOME FOR THE SIX MONTHS ENDED JUNE 30, 2024 AND 2023


		Six months ended June 30,
	Notes	2024	2023
		US$’000, except per share data	US$’000, except per share data
		(Unaudited)	(Unaudited)
REVENUE	3
License revenue		103,027	15,115
Collaboration revenue		171,735	94,432
Other revenue		5,752	119
Total revenue		280,514	109,666
Collaboration cost of revenue		(94,456)	(68,285)
Cost of license and other revenue		(10,734)	—
Other income and gains	3	93,037	20,994
Research and development expenses		(213,590)	(180,680)
Administrative expenses		(67,282)	(49,958)
Selling and distribution expenses		(54,286)	(39,383)
Other expenses		(2)	(7,117)
Fair value loss of warrant liability		—	(85,750)
Finance costs	4	(10,959)	(10,298)
LOSS BEFORE TAX		(77,758)	(310,811)
Income tax expense		(231)	(418)
LOSS FOR THE PERIOD		(77,989)	(311,229)
Attributable to:
Ordinary equity holders of the parent		(77,989)	(311,229)
LOSS PER SHARE ATTRIBUTABLE TO ORDINARY EQUITY HOLDERS OF THE PARENT	5
Basic		(0.21)	(0.91)
Diluted		(0.21)	(0.91)
OTHER COMPREHENSIVE (LOSS)/ INCOME
Other comprehensive income that may be reclassified to profit or loss in subsequent periods:
Exchange differences:
Exchange differences on translation of foreign operations		(58,528)	6,537
Net other comprehensive (loss)/ income that may be reclassified to profit or loss in subsequent periods		(58,528)	6,537
OTHER COMPREHENSIVE (LOSS)/ INCOME FOR THE PERIOD, NET OF TAX		(58,528)	6,537
TOTAL COMPREHENSIVE LOSS FOR THE PERIOD		(136,517)	(304,692)
Attributable to:
Ordinary equity holders of the parent		(136,517)	(304,692)

The accompanying notes are an integral part of the unaudited interim condensed consolidated financial statements.

LEGEND BIOTECH CORPORATION

UNAUDITED INTERIM CONDENSED CONSOLIDATED STATEMENTS OF FINANCIAL POSITION AS AT JUNE 30, 2024 AND CONDENSED CONSOLIDATED STATEMENTS OF FINANCIAL POSITION AS AT DECEMBER 31, 2023


	Notes	June 30, 2024	December 31, 2023
		US$’000	US$’000
		(Unaudited)
NON-CURRENT ASSETS
Property, plant and equipment	6	105,018	108,725
Advance payments for property, plant and equipment		295	451
Right-of-use assets	7	114,718	80,502
Time deposits	10	4,400	4,362
Intangible assets		2,772	4,061
Collaboration prepaid leases		144,552	151,216
Other non-current assets		1,596	1,493
Total non-current assets		373,351	350,810
CURRENT ASSETS
Collaboration inventories	8	18,870	19,433
Trade receivables		13,064	100,041
Prepayments, other receivables and other assets	9	100,628	69,251
Financial assets at fair value through profit or loss	14	42,201	663
Pledged deposits	10	431	357
Time deposits	10	1,048,385	30,341
Cash and cash equivalents	10	201,253	1,277,713
Total current assets		1,424,832	1,497,799
Total assets		1,798,183	1,848,609
CURRENT LIABILITIES
Trade payables		39,490	20,160
Other payables and accruals	11	169,531	132,802
Government grants		545	68
Lease liabilities	7	3,325	3,175
Tax payable		6,566	7,203
Contract liabilities	3	74,845	53,010
Total current liabilities		294,302	216,418
NON-CURRENT LIABILITIES
Collaboration interest-bearing advanced funding	12	291,559	281,328
Lease liabilities long term	7	44,042	44,169
Government grants		6,574	7,305
Contract liabilities	3	2,704	47,962
Other non-current liabilities		—	56
Total non-current liabilities		344,879	380,820
Total liabilities		639,181	597,238
EQUITY
Share capital	13	37	36
Reserves		1,158,965	1,251,335
Total ordinary shareholders’ equity		1,159,002	1,251,371
Total equity		1,159,002	1,251,371
Total liabilities and equity		1,798,183	1,848,609

The accompanying notes are an integral part of the unaudited interim condensed consolidated financial statements.

LEGEND BIOTECH CORPORATION

UNAUDITED INTERIM CONDENSED CONSOLIDATED STATEMENTS OF CHANGES IN EQUITY

FOR THE SIX MONTHS ENDED JUNE 30, 2024 AND 2023


	Attributable to equity holders of the parent
	Share capital	Share premium*		Share-based compensation reserves*		Foreign currency translation reserve*		Retained earnings/ (accumulated losses)*		Total equity
	US$‘000	US$‘000		US$‘000		US$‘000		US$‘000		US$‘000
As at January 1, 2023	33	1,657,015	*	39,049	*	14,671	*	(966,456)	*	744,312
Loss for the period	—	—		—		—		(311,229)		(311,229)
Other comprehensive loss:
Exchange differences on translation of foreign operations	—	—		—		6,537		—		6,537
Total comprehensive loss for the period	—	—		—		6,537		(311,229)		(304,692)
Issuance of ordinary shares relating to private placement for institutional investors, net of issuance costs	1	234,409		—		—		—		234,410
Issuance of ordinary shares relating to registered direct offering, net of issuance costs	1	349,277		—		—		—		349,278
Issuance of ordinary shares relating to the exercise of warrant	1	352,490		—		—		—		352,491
Exercise of share options	—	13,072		(4,554)		—		—		8,518
Reclassification of vested restricted share units	—	18,606		(18,606)		—		—		—
Equity-settled share-based compensation expense	—	—		22,714		—		—		22,714
As at June 30, 2023 (unaudited)	36	2,624,869	*	38,603	*	21,208	*	(1,277,685)	*	1,407,031

As at January 1, 2024	36	2,637,120		54,621		44,304		(1,484,710)		1,251,371
Loss for the period	—	—		—		—		(77,989)		(77,989)
Other comprehensive loss:
Exchange differences on translation of foreign operations	—	—		—		(58,528)		—		(58,528)
Total comprehensive loss for the period	—	—		—		(58,528)		(77,989)		(136,517)
Exercise of share options	—	5,548		(1,843)		—		—		3,705
Reclassification of vested restricted share units	1	32,547		(32,547)		—		—		1
Equity-settled share-based compensation expense	—	—		40,442		—		—		40,442
As at June 30, 2024 (unaudited)	37	2,675,215	*	60,673	*	(14,224)	*	(1,562,699)	*	1,159,002

*These reserve accounts comprise the consolidated reserves of $1,159.0 million and $1,407.0 million in the consolidated statements of financial position as at June 30, 2024 and, 2023, respectively.

The accompanying notes are an integral part of the unaudited interim condensed consolidated financial statements.

LEGEND BIOTECH CORPORATION

UNAUDITED INTERIM CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS

FOR THE SIX MONTHS ENDED JUNE 30, 2024 AND 2023


		Six months ended June 30,
	Notes	2024	2023
		US$’000	US$’000
		(Unaudited)	(Unaudited)
CASH FLOWS PROVIDED BY/ (USED IN), OPERATING ACTIVITIES
Loss before tax		(77,758)	(310,811)
Adjustments for:
Finance income	3	(30,919)	(18,765)
Finance costs	4	10,959	10,298
Provision for inventory reserve		6,425	577
Depreciation of property, plant and equipment	6	5,576	5,303
Loss on disposal of property, plant and equipment		2	141
Amortization of intangible assets		1,251	943
Depreciation of right-of-use assets	7	4,264	3,683
Fair value loss of warrant liability		—	85,750
Fair value gains on financial assets measured at fair value through profit or loss	3	(201)	(756)
Increase in contract liabilities (current)		23,708	—
Decrease in contract liabilities (non-current)		(44,175)	—
Foreign currency exchange (gain)/loss, net	3	(60,704)	7,020
Equity-settled share-based compensation expense		40,442	22,714
Deferred government grant		(293)	(360)
		(121,423)	(194,263)
Decrease/(increase) in trade receivables		86,977	(14,974)
Increase in prepayments, other receivables and other assets		(30,341)	(6,514)
Increase in other non-current assets		(112)	—
Increase in collaboration inventories		(5,862)	(5,419)
Government grant received		85	—
Increase/(decrease) in trade payables		19,285	(11,349)
Increase/(decrease) in other payables and accruals		47,686	(20,263)
Decrease in other non-current liabilities		(56)	(14)
Increase in pledged deposits, net		(71)	—
Cash used in operations		(3,832)	(252,796)
Interest income received		19,285	16,622
Income tax paid		(847)	—
Interest on lease payments		(739)	(609)
Net cash provided by/(used in) operating activities		13,867	(236,783)

The accompanying notes are an integral part of the unaudited interim condensed consolidated financial statements.

LEGEND BIOTECH CORPORATION

UNAUDITED INTERIM CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (CONTINUED)

FOR THE SIX MONTHS ENDED JUNE 30, 2024 AND 2023


		Six months ended June 30,
	Note	2024	2023
		US$’000	US$’000
		(Unaudited)	(Unaudited)
CASH FLOWS USED IN INVESTING ACTIVITIES
Purchase of property, plant and equipment		(9,662)	(10,362)
Purchase of intangible assets		—	(38)
Prepayment to collaborator for collaboration assets		(33,695)	(53,018)
Purchase of financial assets measured at fair value through profit or loss		(150,560)	—
Cash receipts of investment income		1,846	4,037
Cash received from withdrawal of financial assets measured at fair value through profit or loss		108,163	—
Addition in time deposits		(2,194,188)	(432,023)
Decrease in time deposits		1,186,317	385,753
Net cash used in investing activities		(1,091,779)	(105,651)
CASH FLOWS FROM FINANCING ACTIVITIES
Proceeds from registered direct offering, net of issuance costs		—	349,278
Proceeds from exercise of warrant by warrant holder, net of issuance cost		—	199,741
Proceeds from issuance of ordinary shares for follow on public offering, net of issuance costs		—	234,410
Proceeds from exercise of share options		3,704	8,513
Principal portion of lease payments		(1,918)	(2,338)
Net cash provided by financing activities		1,786	789,604
NET (DECREASE)/ INCREASE IN CASH AND CASH EQUIVALENTS		(1,076,126)	447,170
Effect of foreign exchange rate changes, net		(334)	12
Cash and cash equivalents at beginning of year		1,277,713	786,031

CASH AND CASH EQUIVALENTS AT END OF PERIOD	10	201,253	1,233,213
ANALYSIS OF BALANCES OF CASH AND CASH EQUIVALENTS
Cash and bank balances		1,254,469	1,334,482
Less: Pledged deposits		431	1,246
Time deposits		1,052,785	100,023
Cash and cash equivalents as stated in the statement of financial position	10	201,253	1,233,213
Cash and cash equivalents as stated in the statement of cash flows		201,253	1,233,213

The accompanying notes are an integral part of the unaudited interim condensed consolidated financial statements.

LEGEND BIOTECH CORPORATION

NOTES TO THE UNAUDITED INTERIM CONDENSED

CONSOLIDATED FINANCIAL STATEMENTS

1. CORPORATE INFORMATION

Legend Biotech Corporation, (the "Company"), was incorporated on May 27, 2015 as an exempted company in the Cayman Islands with limited liability under the Companies Act (As Revised) of the Cayman Islands. The registered office address of the Company is PO Box 10240, Harbour Place, 103 South Church Street, George Town, Grant Cayman KY1-1002, Cayman Islands.

Legend Biotech Corporation is an investment holding company. The Company’s subsidiaries are principally engaged in the discovery, development, manufacturing and commercialization of novel cell therapies for oncology and other indications.

2.1. BASIS OF PREPARATION

The unaudited interim condensed consolidated financial statements of Legend and its subsidiaries (collectively referred to as the “Company”) for the six months ended June 30, 2024 have been prepared in accordance with International Accounting Standard (“IAS”) 34 Interim Financial Reporting (“IAS34”) issued by the International Accounting Standards Board (the “IASB”).

The accounting policies and basis of preparation adopted in the preparation of these unaudited interim condensed consolidated financial statements are consistent with those followed in the preparation of the Company financial statements for the year ended December 31, 2023. The Company has not early adopted any other standards, interpretation or amendments that have been issued but are not yet effective.

In the opinion of the Company’s management, the accompanying unaudited interim condensed consolidated financial statements contain all normal recurring adjustments necessary to present fairly the financial position, operating results and cash flows of the Company for each of the periods presented. The results of operations for the six months ended June 30, 2024 are not necessarily indicative of results to be expected for any other interim periods or for the year ended December 31, 2023. The condensed consolidated statement of financial position as of December 31, 2023 was derived from the audited consolidated financial statements at that date but does not include all of the disclosures required by the IASB for annual financial statements. These unaudited interim condensed consolidated financial statements should be read in conjunction with the Company’s audited consolidated financial statements for the year ended December 31, 2023.

2.2. NEW STANDARDS, INTERPRETATIONS AND AMENDMENTS ADOPTED BY THE COMPANY

There were no new International Financial Reporting Standards (“IFRS”), amendments or interpretations issued by the IASB that became effective in the six months ended June 30, 2024 that had a material impact on the Company's unaudited interim condensed consolidated financial statements.

3. REVENUE, OTHER INCOME AND GAINS

An analysis of revenue is as follows:


	Six months ended June 30,
	2024	2023
	US$’000 (Unaudited)	US$’000 (Unaudited)
Revenue
License revenue	103,027	15,115
Collaboration revenue	171,735	94,432
Other revenue	5,752	119
Total	280,514	109,666

Janssen Collaboration Agreement

License revenue from licensing of intellectual property is recognized at a point in time with respect to the exclusive worldwide collaboration and license agreement with Janssen Biotech, Inc., a Johnson & Johnson company (“Janssen”), to develop and commercialize cilta-cel (the“Janssen Agreement”). License revenue from licensing of intellectual property represents variable consideration relating to the milestone payments that were constrained in prior years but included in the transaction price when the achievement of the milestones was highly probable. The Company recognized license revenue of $75.1 million for the six months ended June 30, 2024 for milestones achieved under the Janssen Agreement.

Collaboration revenue includes our pro-rata share of collaboration net trade sales for which Janssen is the principal in the sale to the customer under the Janssen Agreement.

Novartis License Agreement

On November 10, 2023, Legend Biotech, through its wholly owned subsidiary, Legend Biotech Ireland Limited, entered into an exclusive, global license agreement with Novartis Pharma AG (the "Novartis License Agreement"). The Company granted Novartis the worldwide rights to develop, manufacture and commercialize LB2102 and other potential chimeric antigen receptor T-cell (CAR-T) therapies selectively targeting Delta-like Ligand 3 (DLL3). The Novartis License Agreement was effective on December 28, 2023, with a $100 million receivable initially recorded, representing the Novartis upfront payment which was then received on January 3rd, 2024. Novartis has also agreed to pay up to $1.01 billion in milestone payments upon achievement of specified clinical, regulatory and commercial milestones, as well as tiered royalties on net sales. We determined that any milestone payments will be recognized upon occurrence as they were determined to relate predominately to the license granted and therefore have been excluded from the transaction price. We determined that any sales-based royalties will be recognized when the related sales occur as they were determined to relate predominately to the license granted and therefore have been excluded from the transaction price. Under the Novartis License Agreement, Legend Biotech will conduct the Legend Phase 1 clinical trial for LB2102 in the U.S. Novartis will conduct all other development, manufacture and commercialization for the licensed product(s). The Company recognized license revenue of $27.9 million for the six months ended June 30, 2024 due to the timing of underlying activities performed in connection with the Novartis License Agreement.

Other Revenue

Other revenue primarily includes supply of materials by us to Novartis under the terms of the Novartis License Agreement.

The following table shows the deferred revenue which is included in contract liabilities for the periods presented:


	June 30,	December 31
	2024	2023
	US$’000 (Unaudited)	US$’000
Contract liabilities (Current)	74,845	53,010
Contract liabilities (Non-Current)	2,704	47,962
Total	77,549	100,972

The following table summarizes the Total other income and gains:


	Six months ended June 30,
	2024	2023
	US$’000 (Unaudited)	US$’000 (Unaudited)
Other income and gains
Other income:
Finance income	30,919	18,765
Government grants*	1,036	1,352
Other	156	4
Total income	32,111	20,121

Gains:
Foreign currency exchange gain, net	60,704	—
Fair value gains on financial assets measured at fair value change through profit or loss	201	756
Other	21	117
Total gains	60,926	873
Total other income and gains	93,037	20,994

*The amount represents subsidies received from local government authorities to support the Company’s business. There were no unfulfilled conditions and other contingencies attached to these government grants.

4. FINANCE COSTS


	Six months ended June 30,
	2024	2023
	US$’000 (Unaudited)	US$’000 (Unaudited)
Interest on lease liabilities	739	609
Collaboration interest-bearing advanced funding	10,220	9,689
Total	10,959	10,298

5. LOSS PER SHARE ATTRIBUTABLE TO ORDINARY EQUITY HOLDERS OF THE PARENT

The calculation of the basic loss per share amount is based on the loss for the period attributable to ordinary equity holders of Legend Biotech Corporation, and the weighted average number of ordinary shares of 364,610,589 and 340,779,779 in issue during the six months ended June 30, 2024 and 2023, respectively.

The calculation of the diluted earnings per share amount is based on the loss for the period attributable to ordinary equity holders of the parent. The weighted average number of ordinary shares used in the calculation is the number of ordinary shares in issue during the period, as used in the basic earnings per share calculation, and the weighted average number of ordinary shares assumed to have been issued at no consideration on the deemed exercise of all dilutive potential ordinary shares into ordinary shares.

No adjustment has been made to the basic loss per share amounts presented for the six months ended June 30, 2024 and 2023, as the impact of the outstanding share options and RSU had an anti-dilutive effect on the basic loss per share amounts presented.

The calculations of basic and diluted loss per share are based on:


	Six months ended June 30,
	2024	2023
	US$’000 (Unaudited)	US$’000 (Unaudited)
Losses
Loss attributable to ordinary equity holders of the parent, used in the basic earnings per share calculation	(77,989)	(311,229)


	Number of shares Six months ended June 30,
	2024	2023
	(Unaudited)	(Unaudited)
Shares
Weighted average number of ordinary shares in issue during the period used in the basic earnings per share calculation	364,610,589	340,779,779

6. PROPERTY, PLANT AND EQUIPMENT

The carrying amounts of the Company’s property, plant and equipment and the movements for the six months ended June 30, 2024 are as follows:


						2024
						US$’000 (Unaudited)
At January 1, 2024
Cost						143,727
Accumulated depreciation						(35,002)
Net carrying amount						108,725
At January 1, 2024, net of accumulated depreciation						108,725
Additions						3,320
Disposals						(983)
Depreciation provided during the period						(5,576)
Exchange realignment						(468)
At June 30, 2024, net of accumulated depreciation						105,018
At June 30, 2024:
Cost						144,388
Accumulated depreciation						(39,370)
Net carrying amount						105,018

7. LEASES

The Company as a lessee

The Company has leases for office, research laboratory and manufacturing facilities, equipment, vehicles, land and collaboration assets. The terms of the leases vary, although most generally have lease terms between 3 and 29 years. Lump sum payments were made upfront to acquire the leasehold land from the owners with lease periods of 50 years, and no ongoing payments will be made under the terms of these leasehold land. Leases with terms of 12 months or less are expensed as incurred. Collaboration assets represent the Company’s share of assets leased to the collaboration from Janssen, which purchased the assets on behalf of the collaboration, in connection with the Janssen Agreement. Collaboration assets under construction that will be leased to the collaboration from Janssen when placed into service are classified as collaboration prepaid leases on the consolidated financial statements.

(a)Right-of-use assets

The carrying amounts of the Company’s right-of-use assets and the movements for the six months ended June 30, 2024 are as follows:


						2024
						US$’000 (Unaudited)

Right-of-use assets at January 1, 2024						80,502
Additions						40,215

Exchange realignment						(1,735)
Depreciation of right-of-use assets						(4,264)
Right-of-use assets at June 30, 2024						114,718

(b)Lease liabilities

At the commencement date of the lease, the Company recognizes lease liabilities measured at the present value of lease payments to be made over the lease term. The balance of the Company’s lease liabilities and the movements for the six months ended June 30, 2024 are as follows:


						2024
						US$’000 (Unaudited)
Carrying amount at January 1, 2024						47,344
Additions						3,266
Accretion of interest recognized during the period						739
Payments						(2,657)
Exchange realignment						(1,325)
Carrying amount at June 30, 2024						47,367
Analyzed into:
Current portion						3,325
Non-current portion						44,042
Total						47,367

8. COLLABORATION INVENTORIES


	June 30, 2024	December 31, 2023
	US$’000 (Unaudited)	US$’000
Raw materials	14,041	13,155
Work-in-process	4,236	2,990
Finished goods	593	3,288
Total collaboration inventories	18,870	19,433

The Company's reserve for inventory was $15.3 million and $8.9 million as of June 30, 2024 and December 31, 2023, respectively. The Company’s reserve for inventory was primarily related to expired material and certain batches or units of product that did not meet quality specifications that were charged to collaboration cost of sales.

9. PREPAYMENTS, OTHER RECEIVABLES AND OTHER ASSETS


	June 30, 2024	December 31, 2023
	US$’000 (Unaudited)	US$’000

Other collaboration receivables	83,860	54,078

Other receivables	1,870	837
Lease receivables	344	1,388
VAT recoverable	2,237	717
Prepayments	12,317	12,231
Total	100,628	69,251

None of the above assets is either past due or impaired. The financial assets included in the above balances relate to receivables for which there was no recent history of default. The Company estimated that the expected credit loss for the above receivables as at June 30, 2024 and December 31, 2023 is insignificant.

10. CASH AND CASH EQUIVALENTS, TIME DEPOSITS AND PLEDGED DEPOSITS


	June 30, 2024	December 31, 2023
	US$’000 (Unaudited)	US$’000

Cash and bank balances	1,254,469	1,312,773
Less: Pledged deposits	(431)	(357)
Time deposits	(1,052,785)	(34,703)

Cash and cash equivalents	201,253	1,277,713

Denominated in USD	178,793	1,254,969
Denominated in RMB	17,205	12,675
Denominated in EUR	5,255	10,069

Cash and cash equivalents	201,253	1,277,713

The cash and cash equivalents of the Company denominated in Renminbi (“RMB”) amounted to $17.2 million and $12.7 million in the consolidated statements of financial position as at June 30, 2024 and December 31, 2023, respectively. The RMB is not freely convertible into other currencies, however, under Greater China Foreign Exchange Control Regulations and Administration of Settlement, Sale and Payment of Foreign Exchange Regulations, the Company is permitted to exchange RMB for other currencies through banks authorized to conduct foreign exchange business.

The pledged deposit as at June 30, 2024 was primarily pledged for office space and credit card facilities, while the pledged deposit as at December 31, 2023 was pledged for credit card facilities.

Cash and cash equivalents earns interest at floating rates based on daily bank deposit rates. The bank balances are deposited with creditworthy banks with no recent history of default. The carrying amounts of the cash and cash equivalents approximate to their fair values.

11. OTHER PAYABLES AND ACCRUALS


	June 30, 2024	December 31, 2023
	US$’000 (Unaudited)	US$’000
Accrued payroll	22,450	30,974
Accrued expense	108,205	71,462
Other payables	21,681	11,944
Payable for collaboration assets	15,350	16,338
Other tax payables	1,845	2,084
Total	169,531	132,802

Other payables are non-interest-bearing and repayable on demand.

12. COLLABORATION INTEREST-BEARING ADVANCED FUNDING

Effective interest rate (%)

Maturity

June 30,
2024

US$’000
(Unaudited)

Non-current

Loans from a collaborator

8.26

No specific maturity date

291,559

Pursuant to the license and collaboration agreement entered into with a collaborator, the Company is entitled to receive funding advances from the collaborator when certain operational conditions are met. As a result, the Company took an initial funding advance with principal amounting to $17.3 million on June 18, 2021, a second funding advance with principal amounting to $53.1 million on September 17, 2021, a third funding advance with principal amounting to $49.3 million on December 17, 2021, a forth funding advance with principal amounting to $5.3 million on March 18, 2022, a fifth funding advance with principal amounting to $60.9 million on June 17, 2022, a sixth funding advance with principal amounting to $60.5 million on September 16, 2022, and a seventh funding advance with principal amounting to $3.6 million on December 16, 2022, by reducing the same amount of other payables due to the collaborator, respectively (collectively, the “Funding Advances”).

These Funding Advances are accounted for as interest-bearing borrowings funded by the collaborator, constituted by a principal amounting to $250.0 million and applicable interests accrued amounting to $41.6 million upon such principal. The respective interest rate of each borrowing has transitioned from London Interbank Offered Rate (LIBOR) to Secured Overnight Financing Rate (SOFR) in accordance with the LIBOR ACT . Thus, outstanding advances accrue interest at 12 month CME term SOFR plus LIBOR/SOFR adjustment (12 month) plus a margin of 2.5%. For each of the seven batches of funding advances, interest started to accrue from June 18, 2021, September 17, 2021, December 17, 2021, March 18, 2022, June 17, 2022, September 16, 2022, and December 16, 2022, respectively.

Pursuant to the terms of the license and collaboration agreement, the collaborator may recoup the aggregate amount of Funding Advances, together with interest thereon, from Company’s share of pre-tax profits from the first profitable year of the collaboration program and, subject to some limitations, from milestone payments due to the Company under the Janssen Agreement. The Company’s management estimated the loan will not be recouped by the collaborator within one year, nor does the Company expect to repay the funding advances within one year, and thus the loan was classified as a long-term liability.

13. SHARE CAPITAL AND SHARE PREMIUM


	June 30, 2024	December 31, 2023
	US$’000 (Unaudited)	US$’000
Authorized:
2,000,000,000 ordinary shares of $0.0001 each	200	200
Issued and fully paid:
366,341,403 and (2023: 363,822,069) ordinary shares of $0.0001 each	37	36

A summary of movements in the Company’s share capital and share premium is as follows:


	Number of shares in issue	Share capital	Share premium	Total
		US$’000	US$’000	US$’000
At December 31, 2023 and January 1, 2024	363,822,069	36	2,637,120	2,637,156
Exercise of share options	1,045,392	—	5,548	5,548
Reclassification of vesting of restricted share units	1,473,942	1	32,547	32,548
At June 30, 2024 (Unaudited)	366,341,403	37	2,675,215	2,675,252

14. FAIR VALUE AND FAIR VALUE HIERARCHY OF FINANCIAL INSTRUMENTS

Management has assessed that the fair values of cash and cash equivalents, pledged deposits, time deposits, financial assets included in prepayments, other receivables and other assets, trade receivables, trade payables and financial liabilities included in other payables and accruals approximate to their carrying amounts largely due to the short-term maturities of these instruments.

The Company’s finance department, headed by the Corporate Controller, is responsible for determining the policies and procedures for the fair value measurement of financial instruments. The finance department reports directly to the Corporate Controller. At June 30, 2024, the finance department analyzed the movements in the values of financial instruments and determined the major inputs applied in the valuation. The valuation was reviewed and approved by the finance manager. The valuation process and results are discussed with the directors once a year for annual financial reporting.

The fair values of the financial assets and liabilities are included at the amount at which the instrument could be exchanged in a current transaction between willing parties, other than in a forced or liquidation sale.

The following table illustrates the fair value measurement hierarchy of the Company’s financial instruments:

Asset measured at fair value:

As at June 30, 2024 (Unaudited)

Fair value measurement using

Quoted
prices
in active
markets
(Level 1)

Significant
observable
inputs
(Level 2)

Significant
unobservable
inputs
(Level 3)

Total

US$’000

Financial assets at fair value through profit or loss

42,201

—

42,201

As at December 31, 2023

Fair value measurement using

Quoted
prices
in active
markets
(Level 1)

Significant
observable
inputs
(Level 2)

Significant
unobservable
inputs
(Level 3)

Total

US$’000

Financial assets at fair value through profit or loss

663

—

663

Financial assets measured at fair value consists of money market funds.

During the six months ended June 30, 2024, there were no transfers of fair value measurements between Level 1 and Level 2 and no transfers into or out of Level 3 for both financial assets and financial liabilities.

15. APPROVAL OF THE INTERIM CONDENSED CONSOLIDATED FINANCIAL STATEMENTS

The interim condensed consolidated financial statements were approved and authorized for issue by the Board of Directors on August 8, 2024.

Exhibit 99.3

In this Management’s Discussion and Analysis of Financial Condition and Results of Operations ("MD&A"), unless otherwise indicated or the context otherwise requires, “we,” “us,” “our,” the “Company” and “Legend Biotech” refer to Legend Biotech Corporation and its consolidated subsidiaries. References to “GenScript” refer to GenScript Biotech Corporation, our largest shareholder. “Legend Biotech,” the Legend logo and other trademarks or service marks of the Company appearing in this MD&A are the property of the Company. Solely for convenience, the trademarks, service marks and trade names referred to in this MD&A are without the ®, ™ and other similar symbols, but such references are not intended to indicate, in any way, that we will not assert, to the fullest extent under applicable law, our rights or the rights of the applicable licensors to these trademarks, service marks and trade names. CARVYKTI is a registered trademark in the United States of Johnson & Johnson. Other trade names, trademarks and service marks of other companies appearing in this Annual Report are the property of their respective holders. We do not intend our use or display of other companies’ trademarks, service marks or trade names to imply a relationship with, or endorsement or sponsorship of us by, any other person.

Management’s Discussion and Analysis of Financial Condition and Results of Operations

You should read the following discussion and analysis of our financial condition and results of operations together with our interim condensed consolidated financial statements and the accompanying notes.

This MD&A contains forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, or the Securities Act, and Section 21E of the Securities Exchange Act of 1934, as amended, or the Exchange Act. All statements other than statements of present and historical facts and conditions are forward-looking statements. Forward-looking statements can often be identified by words or phrases, such as “may,” “will,” “expect,” “anticipate,” “aim,” “estimate,” “intend,” “plan,” “believe,” “is/are likely to,” “potential,” “continue” or other similar expressions. Such forward-looking statements reflect our current expectations and views of future events, but are not assurances of future performance. Instead, they are based on our current beliefs, expectations and assumptions regarding the future of our business, future plans and strategies, our financial needs, our operational results and other future conditions. These forward-looking statements involve various risks and uncertainties. Many important factors may adversely affect such forward-looking statements and cause actual results to differ from those in any forward-looking statement, including, without limitation, our strategies and objectives; statements relating to CARVYKTI, including our expectations for CARVYKTI, such as our manufacturing and commercialization expectations for CARVYKTI and the potential effect of treatment with CARVYKTI; statements related to Legend Biotech’s ability to achieve operating profit; uncertainties involved in the development of new pharmaceutical products; unexpected clinical trial results, including as a result of additional analysis of existing clinical data or unexpected new clinical data; unexpected regulatory actions or delays, including requests for additional safety and/or efficacy data or analysis of data, or government regulation generally; unexpected delays as a result of actions undertaken, or failures to act, by our third party partners; uncertainties arising from challenges to Legend Biotech’s patent or other proprietary intellectual property protection, including the uncertainties involved in the U.S. litigation process; competition in general; government, industry, and general product pricing and other political pressures; commercialization factors, including regulatory approval and pricing determinations; disruptions to access to raw materials; delays or disruptions at manufacturing facilities; proliferation and continuous evolution of new technologies; dislocations in the capital markets; and other important factors described under “Risk Factors” in our Annual Report on Form 20-F filed with the Securities and Exchange Commission on March 19, 2024 (the “Annual Report”) and under “Risk Factors” in any other reports that we file with the Securities and Exchange Commission. As a result of these factors, we cannot assure you that the forward-looking statements in this interim report will prove to be accurate. Furthermore, if our forward-looking statements prove to be inaccurate, the inaccuracy may be material. In light of the significant uncertainties in these forward-looking statements, you should not regard these statements as a representation or warranty by us or any other person that we will achieve our objectives and plans in any specified time frame or at all. We undertake no obligation to publicly update any forward-looking statements, whether as a result of new information, future events or otherwise, except as required by law. In addition, even if our results of operations, financial condition and liquidity are consistent with the forward-looking statements contained in this report, those results or developments may not be indicative of results or developments in subsequent periods.

Overview

We are a global biopharmaceutical company engaged in the discovery, development, manufacturing and commercialization of novel cell therapies for oncology and other indications. Our team of approximately 2,200 employees in the United States, China and Europe, our differentiated technology, as well as our global development and manufacturing expertise provide us with the ability to generate, test and manufacture next-generation cell therapies targeting indications with high unmet needs. Our lead product candidate, ciltacabtagene autoleucel, ("cilta-cel") (referred to as LCAR- B38M for purposes of our LEGEND-2 trial), is a CAR-T cell therapy we are jointly developing with our strategic partner, Janssen, for the treatment of multiple myeloma (“MM”). Clinical trial results achieved to date demonstrate that cilta-cel has the potential to deliver deep and durable anti-tumor responses in relapsed and refractory multiple myeloma (“RRMM”) patients with a manageable safety profile.

On February 28, 2022, cilta-cel was approved by the U.S. Food and Drug Administration (the “FDA”) under the trademark CARVYKTI for the treatment of adults with RRMM who have received four or more prior lines of therapy, including a proteasome inhibitor, an immunomodulatory agent, and an anti-CD38 monoclonal antibody. CARVYKTI was our first product approved by a health authority. On April 5, 2024, the FDA approved CARVYKTI® for the treatment of adult patients with relapsed or refractory multiple myeloma who have received at least one prior line of therapy, including a proteasome inhibitor (PI), and an immunomodulatory agent (IMiD), and are refractory to lenalidomide.

Recent Business Developments

•CARVYKTI® (ciltacabtagene autoleucel; cilta-cel) net trade sales of approximately $186 million.

•MHRA and Health Canada approved CARVYKTI® in earlier lines of treatment for adult patients with relapsed and lenalidomide-refractory multiple myeloma.

•CARVYKTI® demonstrates positive overall survival results in second interim analysis of CARTITUDE-4 study.

•Cash and cash equivalents, deposits and short-terms investments of $1.3 billion, as of June 30, 2024, which we believe will provide financial runway into 2026, when we anticipate achieving an operating profit.

Global Economic Conditions

Changes in economic conditions, supply chain constraints, logistics challenges, labor shortages, the Russia-Ukraine war, the conflict between Israel and Hamas and steps taken by governments and central banks, have led to higher inflation, which has led to an increase in costs and has caused changes in fiscal and monetary policy, including increased interest rates. Our product manufacturing in the U.S., Belgium, and China has continued. Currently we have not experienced any material impact to our material supply chain or as a result of inflation and rising interest rates. Increased quantities of certain raw materials and consumables have been stocked as an appropriate safety measure. We believe we have established robust sourcing strategies for all necessary materials and do not expect any significant impact.

Although we do not believe that these macroeconomic conditions have had a material impact on our financial position or results of operations to date, if these changes in economic conditions continue or if they increase in severity, it could result in further economic uncertainty and volatility in the capital markets in the near term, and could negatively affect our operations.

Comparison of Six Months Ended June 30, 2024 and 2023

The following table summarizes our results of operations for the six months ended June 30, 2024 and 2023:


	Six months ended June 30,		Variance
	2024	2023
	US$’000
Consolidated Statement of Operations Data:
Revenue
License revenue	103,027	15,115	87,912
Collaboration revenue	171,735	94,432	77,303
Other revenue	5,752	119	5,633
Total revenue	280,514	109,666	170,848
Operating expenses:
Collaboration cost of revenue	(94,456)	(68,285)	(26,171)
Cost of license and other revenue	(10,734)	—	(10,734)
Research and development expenses	(213,590)	(180,680)	(32,910)
Administrative expenses	(67,282)	(49,958)	(17,324)
Selling and distribution expenses	(54,286)	(39,383)	(14,903)
Other income and gains	93,037	20,994	72,043
Other expenses	(2)	(7,117)	7,115
Fair value gain of warrant liability	—	(85,750)	85,750
Finance costs	(10,959)	(10,298)	(661)
Loss before tax	(77,758)	(310,811)	233,053
Income tax expense	(231)	(418)	187
Loss for the period	(77,989)	(311,229)	233,240

Revenue

License Revenue

License revenue for the six months ended June 30, 2024, was $103.0 million compared to $15.1 million for the six months ended June 30, 2023. This increase of $87.9 million was primarily driven by a $60.0 million increase in revenue recognized due to the nature of and timing of milestones achieved as outlined in the Global Development Plan under the Janssen Agreement for cilta-cel.

Additionally, the increase in license revenue is driven by the recognition of $27.9 million of revenue due to the timing of underlying activities performed in connection with the global license agreement with Novartis Pharma AG (the "Novartis License Agreement") to develop, manufacture, and commercialize LB2102 and other potential CAR-T therapies selectively targeting DLL3. We did not recognize any license revenue from the Novartis License Agreement for the six months ended June 30, 2023.

Collaboration Revenue

Collaboration revenue for the six months ended June 30, 2024, was $171.7 million, compared to $94.4 million for the six months ended June 30, 2023. This increase of $77.3 million was due to an increase in revenue generated from sales of CARVYKTI in connection with the Janssen Agreement.

Other Revenue

Other revenue for the six months ended June 30, 2024, was $5.8 million, compared to $0.1 million for the six months ended June 30, 2023. This increase of $5.7 million was primarily driven by materials provided to Novartis in connection with the Novartis License Agreement.

Operating Expenses

Collaboration cost of revenue

Collaboration cost of revenue for the six months ended June 30, 2024, was $94.5 million compared to $68.3 million for the six months ended June 30, 2023. The increase of $26.2 million is primarily due to an increase of our share of cost of sales incurred in connection with CARVYKTI sales under the Janssen Agreement.

Cost of license and other revenue

Cost of license and other revenue for the six months ended June 30, 2024, was $10.7 million and consisted of costs in connection with the Novartis License Agreement. We did not incur any cost of license and other revenue for the six months ended June 30, 2023.

Research and Development Expenses

Research and development expenses for the six months ended June 30, 2024, were $213.6 million compared to $180.7 million for the six months ended June 30, 2023. This increase of $32.9 million was primarily due to continuous research and development activities in cilta-cel, including start up costs for clinical production in Belgium and continued investment in our solid tumor programs.

Administrative Expenses

Administrative expenses for the six months ended June 30, 2024, were $67.3 million compared to $50.0 million for the six months ended June 30, 2023. The increase of $17.3 million was due to our expansion of administrative functions and infrastructure to increase manufacturing capacity.

Selling and Distribution Expenses

Selling and distribution expenses for the six months ended June 30, 2024, were $54.3 million compared to $39.4 million for the six months ended June 30, 2023. This increase of $14.9 million was due to costs associated with commercial activities for cilta-cel, including the expansion of the sales force and second line indication launch preparation.

Other Income and Gains

Other income and gains for the six months ended June 30, 2024, were $93.0 million compared to $21.0 million for the six months ended June 30, 2023. The increase of $72.0 million was primarily due to increases in interest income and unrealized foreign currency exchange gains in 2024.

Other Expenses

Other expenses for the six months ended June 30, 2024 decreased by approximately $7.1 million compared to the six months ended June 30, 2023, driven primarily due to unrealized foreign currency exchange losses in 2023 and unrealized foreign currency exchange gains in 2024.

Finance Costs

Finance costs for the six months ended June 30, 2024, were approximately $11.0 million compared to approximately $10.3 million for the six months ended June 30, 2023. The $0.7 million increase was primarily due to

interest on advance funding, which is interest-bearing borrowings funded by Janssen under the Janssen Agreement and constituted by principal and applicable interests upon such principal.

Fair Value Gain of Warrant Liability

There was no fair value gain or loss of warrant liability for the six months ended June 30, 2024 because the warrant was exercised on May 11, 2023. The fair value gain of the warrant for the six months ended June 30, 2023 was $85.8 million.

Income Tax Expense

Income tax expense for the six months ended June 30, 2024, was $0.2 million, compared to $0.4 million for the six months ended June 30, 2023.

Loss for the Period

For the six months ended June 30, 2024, net loss was $78.0 million, or $0.21 per share, compared to a net loss of $311.2 million, or $0.91 per share, for the six months ended June 30, 2023.

Liquidity and Capital Resources

Sources of Liquidity

Since our inception, we have incurred significant operating losses. We expect to incur operating losses over the next several years as we continue the commercialization of CARVYKTI and advance the preclinical and clinical development of our research programs and product candidates. Additionally, over the next several years, we expect to incur significant capital expenditures associated with ramping up our manufacturing capabilities for our commercial product. Based on our cash and cash equivalents, deposits, and investments of $1.3 billion, as of June 30, 2024, we believe that we will be able to fund our planned operations and capital expenditure requirements into 2026, when we expect to begin to achieve an operating profit. We may, in the future, pursue additional cash resources through a combination of equity or debt financings, collaborations, licensing arrangements or other sources to maintain a certain level of working capital.

With the exception of our first product, CARVYKTI, which was initially approved by the FDA on February 28, 2022, we do not currently have any approved products and we have not generated any revenue from product sales for other products. From inception through June 30, 2024, we have funded our operations primarily with approximately:

•$3.9 million in capital contributions from Genscript;

•$160.5 million in gross proceeds from the sale of our Series A preference shares;

•$760.0 million in upfront and milestone payments from Janssen under our collaboration and license agreement;

•$450.1 million in net proceeds from our U.S. initial public offering and an additional $12 million from a concurrent private placement with Genscript;

•$300.0 million in net proceeds from our private placement to an investor and related warrant issuance in May 2021;

•$323.4 million in net proceeds from our public offering of ADSs that closed in December 2021;

•$250.0 million in advances from Janssen under our the Janssen Agreement;

•$377.6 million in net proceeds from our public offering of ADSs that closed in July 2022;

•$234.4 million in net proceeds from private placements to certain investors in May and June 2023;

•$349.3 million in net proceeds from our public offering of ADS that closed in May 2023;

•$199.7 million in net proceeds from the exercise in full of a warrant held by one of our investors; and

•$100.0 million upfront payment from Novartis under the Novartis License Agreement.

As of June 30, 2024, we had approximately $0.2 billion in cash and cash equivalents, approximately $1.1 billion of time deposits, approximately $42.2 million of financial assets measured at fair value through profit or loss and accumulated losses of $1.6 billion.

Certain of our subsidiaries, including those registered as wholly foreign-owned enterprises in the People's Republic of China (the "PRC"), are required to set aside at least 10.0% of their after-tax profits to their general reserves until such reserves reach 50.0% of their registered capital. Under PRC regulations, foreign-invested enterprises may pay dividends only out of their accumulated profit, if any, as determined in accordance with PRC accounting standards and regulations. A

PRC company is not permitted to distribute any profits until any losses from prior fiscal years have been offset. Profits retained from prior fiscal years may be distributed together with distributable profits from the current fiscal year. Although we do not currently require any such dividends from our PRC subsidiaries to fund our operations, should we require additional sources of liquidity in the future, such restrictions may have a material adverse effect on our liquidity and capital resources. For more information, see “Item 4.B-Business Overview - Government Regulation - PRC Regulation - Other PRC National- and Provincial-Level Laws and Regulations - Regulations Relating to Dividend Distributions” in our Annual Report.

Cash Flows

The following table shows a summary of our cash flow:


	Six months ended June 30,
	2024	2023
	US$’000 (Unaudited)
Net cash provided by/(used in) operating activities	13,867	(236,783)
Net cash used in investing activities	(1,091,779)	(105,651)
Net cash provided by financing activities	1,786	789,604
Net (decrease)/increase in cash and cash equivalents	(1,076,126)	447,170

Operating Activities

Net cash provided by operating activities for the six months ended June 30, 2024 was $13.9 million, primarily as a result of net loss before tax of $77.8 million after adjusting for non-cash items, and changes in operating assets and liabilities. Non-cash items mainly included $30.9 million of finance income, $11.0 million of finance cost, $6.4 million for the provision for inventory reserves, $5.6 million of depreciation expense of property, plant and equipment, $4.3 million of depreciation of right-of-use assets, $60.7 million of foreign exchange gains and $40.4 million of equity-settled share-based compensation expenses and an increase in contract liabilities (current) of $23.7 million and a decrease in contract liabilities (non-current) of $44.2 million. Changes in operating assets and liabilities mainly include a decrease in trade receivables of $87.0 million, increase in prepayment, other receivable and other assets of $30.3 million, increase in collaboration inventories of $5.9 million, increase in trade payables of $19.3 million, increase in other payables and accruals of $47.7 million. Cash items primarily include interest income received of $19.3 million.

Net cash used in operating activities for the six months ended June 30, 2023 was $236.8 million, primarily as a result of net loss before tax of $310.8 million after adjusting for non-cash items, and changes in operating assets and liabilities. Non-cash items are mainly from $85.8 million of fair value loss of warrant liability and $22.7 million of equity-settled share-based compensation expense. Changes in operating assets and liabilities mainly include a decrease in trade payables of $11.3 million, a decrease in other payables and accruals $20.3 million and an increase in trade receivables $15.0 million.

Investing Activities

Net cash used in investing activities for the six months ended June 30, 2024, was $1.1 billion, consisting primarily of purchases of time deposits of $2.2 billion, purchases of financial assets measured at fair value through profit or loss of $150.6 million, prepayments to Janssen for collaboration assets of $33.7 million and purchases of property, plant and equipment of $9.7 million. These were partially offset by decreases of time deposits of $1.2 billion and cash received from the withdrawal of financial assets measured at fair value through profit or loss of $108.2 million.

Net cash used in investing activities for the six months ended June 30, 2023 was $105.7 million, consisting primarily of the prepayment to Janssen for collaboration assets of $53.0 million and an increase of time deposits of $432.0 million, offset by a decrease of time deposits of $385.8 million.

Financing Activities

Net cash provided by financing activities for the six months ended June 30, 2024 was $1.8 million, consisting primarily of the increase in proceeds from exercise of share options of $3.7 million, partially offset by the principal portion of lease payments of $1.9 million.

Net cash provided by financing activities for the six months ended June 30, 2023 was $789.6 million, consisting primarily of net proceeds from registered direct offering of $349.3 million, $199.7 million of net proceeds from the exercise of warrant by the warrant holder, and $234.4 million of net proceeds from the issuance of ordinary shares to institutional investors.

Capital Expenditure

Our capital expenditures for the six months ended June 30, 2024 and 2023 amounted to $35.5 million and $67.1 million, respectively. These expenditures primarily consisted of property, plant, equipment and collaboration prepaid leases.

Funding Requirements

We expect our expenses to increase in connection with our ongoing activities, particularly as we continue the research and development of, continue or initiate clinical trials of, and seek marketing approval for, our product candidates. In addition, we expect to continue to incur significant commercialization expenses for CARVYKTI related to program sales, marketing, manufacturing and distribution to the extent that such sales, marketing, manufacturing and distribution are not the responsibility of potential collaborators. For example, in addition to investing in our own facilities, we have supplemented our manufacturing capabilities and infrastructure by entering into agreements with CMOs. Furthermore, we expect to incur additional costs associated with operating as a public company. Accordingly, we will need to obtain substantial additional funding in connection with our continuing operations. If we are unable to raise capital when needed or on attractive terms, we would be forced to delay, reduce or eliminate our research and development programs or future commercialization efforts.

Although consequences of the macroeconomic conditions, including global conflicts and inflation, and resulting economic uncertainty could adversely affect our liquidity and capital resources in the future, and cash requirements may fluctuate based on the timing and extent of many factors such as those discussed below, we currently expect our existing cash and cash equivalents will enable us to fund our operating expenses and capital expenditure requirements for at least the next 12 months. Our future capital requirements will depend on many factors, including:

•the scope, progress, results and costs of product discovery, preclinical studies and clinical trials;

•the scope, prioritization and number of our research and development programs;

•the costs, timing and outcome of regulatory review of our product candidates;

•our ability to establish and maintain collaborations on favorable terms, if at all;

•the achievement of milestones or occurrence of other developments that trigger payments under the Janssen Agreement and any other collaboration agreements we enter into;

•the extent to which we are obligated to reimburse, or entitled to reimbursement of, clinical trial costs under collaboration agreements, if any;

•the costs of preparing, filing and prosecuting patent applications, maintaining and enforcing our intellectual property rights and defending intellectual property-related claims;

•the extent to which we acquire or in-license other product candidates and technologies;

•the costs of securing manufacturing arrangements for commercial production; and

•the costs of establishing or contracting for sales and marketing capabilities if we obtain regulatory approvals to market our product candidates.

In addition to cilta-cel, we have a broad portfolio of earlier-stage product candidates. Identifying potential product candidates and conducting preclinical studies and clinical trials is a time- consuming, expensive and uncertain process that takes many years to complete, and we may never generate the necessary data or results required to obtain marketing approval and achieve product sales for such product candidates. In addition, our product candidates, if approved, may not achieve commercial success. Our commercial revenues, if any, will be derived from sales of product candidates that we do not expect to be commercially available for many years, if at all. Accordingly, we will need to continue to rely on additional financing to achieve our business objectives. Adequate additional financing may not be available to us on acceptable terms, or at all.

Until such time, if ever, as we can generate substantial product revenues, we expect to finance our cash needs through a combination of equity offerings, debt financings, collaborations, strategic alliances and licensing arrangements. To the extent that we raise additional capital through the sale of equity or convertible debt securities, holders of our ADSs will be diluted, and the terms of these securities may include liquidation or other preferences that adversely affect the rights of our shareholders. Debt financing, if available, may involve agreements that include covenants limiting or restricting our ability to take specific actions, such as incurring additional debt, making capital expenditures or declaring dividends.

If we raise funds through additional collaborations, strategic alliances or licensing arrangements with third parties, we may have to relinquish valuable rights to our technologies, future revenue streams, research programs or product candidates or to grant licenses on terms that may not be favorable to us. If we are unable to raise additional funds through equity or debt financings when needed, we may be required to delay, limit, reduce or terminate our product development or future commercialization efforts or grant rights to develop and market that we would otherwise prefer to develop and market ourselves.

Under the Janssen Agreement, until such time as our collaboration experiences its first profitable year, we are entitled to receive advances from Janssen if the collaboration’s estimated working capital for any year falls below $50 million. In such event, Janssen provides advances to us in an amount equal to the excess of $50 million over the collaboration’s working capital for the year. The total amount of such advances in any calendar year may not exceed $125 million and the total amount of such advances outstanding at any time may not exceed $250 million. The interest rate pursuant to the Janssen Agreement has transitioned in accordance with the LIBOR Act. Thus, outstanding advances accrue interest at 12 month CME term Secured Overnight Financing Rate (“SOFR”) plus LIBOR/SOFR adjustment (12 month) plus a margin of 2.5%. Janssen has the right to recoup such advances and interest from our share of the collaboration’s pre-tax profits and, subject to some limitations, from milestone payments due to us under the Janssen Agreement. We are not otherwise obligated to repay the advances or interest, except in connection with our change in control or a termination of the Janssen Agreement by Janssen due to our material breach of the agreement. We may at any time in our discretion voluntarily pre-pay any portion of the then outstanding advances or associated interest. As of June 30, 2024, the aggregate outstanding principal amount of such advances and interest were approximately $250.0 million and $41.6 million, respectively.

Quantitative and Qualitative Disclosures About Market Risk

Our cash is held in readily available operating accounts and short to medium term deposits and securities. These securities are principal secured and not adversely impacted by interest rate fluctuations. As a result, a change in market interest rates would not have any significant impact on our cash balance.

The interest rate pursuant to our collaboration and license agreement with Janssen, has transitioned in accordance with the LIBOR Act. Thus, outstanding advances accrue interest at twelve month CME term SOFR plus LIBOR/SOFR adjustment (12 month) plus a margin of 2.5%. Accordingly, changes in SOFR could result in fluctuations in our cash flow. For example, based on the $250.0 million aggregate principal amount of advances outstanding from Janssen as of June 30, 2024, a 0.5% (fifty basis point) per annum increase in SOFR would result in an additional $1.3 million per year in interest payable by the Company.

Inflation generally affects us by increasing our cost of labor and clinical trial costs. We do not believe that inflation had a material effect on our business, financial condition or results of operations during the six months ended June 30, 2024 and 2023.

We also do not believe that we are exposed to any material foreign currency exchange rate risk.

Legend Biotech Reports Second Quarter 2024 Results and Recent Highlights

•CARVYKTI® (ciltacabtagene autoleucel; cilta-cel) net trade sales of approximately $186 million

•MHRA and Health Canada approved CARVYKTI® in earlier lines of treatment for adult patients with relapsed and lenalidomide-refractory multiple myeloma

•CARVYKTI® demonstrates positive overall survival results in second interim analysis of CARTITUDE-4 study

•Cash and cash equivalents, deposits and short-term investments of $1.3 billion, as of June 30, 2024, which Legend Biotech believes will provide financial runway into 2026, when Legend Biotech anticipates achieving an operating profit

SOMERSET, N.J.—August 9, 2024— Legend Biotech Corporation (NASDAQ: LEGN) (Legend Biotech), a global leader in cell therapy, today reported its second quarter 2024 unaudited financial results and key corporate highlights.

“In the second quarter, approval of CARVYKTI® in the second line increased demand and interest from patients and the healthcare community. Momentum for CARVYTKI® is growing and we are excited to see it helping not only later line patients, but an increasing number of earlier line patients. I am encouraged by the progress we have been making in both the inpatient and outpatient settings, enabling more patients to receive our transformative one-time treatment,” said Ying Huang, Ph.D., Chief Executive Officer of Legend Biotech. “We look forward to starting commercial production at our Obelisc facility in Belgium later this year in order to meet the growing demand, and we remain laser-focused on increasing our manufacturing capacity.”

Regulatory Updates

•The United Kingdom’s Medicines and Healthcare products Regulatory Agency (MHRA) approved CARVYKTI® for the treatment of adult patients with relapsed and refractory multiple myeloma, who have received at least one prior therapy, including an immunomodulatory agent (IMiD) and a proteasome inhibitor (PI), have demonstrated disease progression on the last therapy and are refractory to lenalidomide.

•Health Canada approved CARVYKTI® for the treatment of adult patients with multiple myeloma, who have received one to three prior lines of therapy including a PI and an IMiD, and who are refractory to lenalidomide.

Key Business Developments

•Novartis Pharmaceuticals Corporation initiated clinical production in July 2024.

•Completed CARTITUDE 5 enrollment in July 2024.

•Announced positive results from a second interim analysis of the Phase 3 CARTITUDE-4 study demonstrating a statistically significant and clinically meaningful improvement in overall survival for multiple myeloma patients treated with CARVYKTI® versus standard-of-care treatment regimens. These new results will be presented at an upcoming medical meeting and shared with regulatory agencies for label updates worldwide.

•New data from the Phase 2 CARTITUDE-2 Cohort D study and new and updated data from the Phase 3 CARTITUDE-4 study of cilta-cel were featured at the 2024 American Society of Clinical Oncology (ASCO) Annual Meeting (Abstracts #7504 and 7505) and European Hematology Association (EHA) 2024 Hybrid Congress (Abstract #S205).

•On June 28, 2024, Legend Biotech received a milestone payment of $30 million in connection with the Janssen Agreement.

•On August 8, 2024, Peter Salovey, Ph.D. was appointed to the Company's Board of Directors, effective August 9, 2024.

* In December 2017, Legend Biotech entered into an exclusive worldwide collaboration and license agreement with Janssen Biotech, Inc., a Johnson & Johnson company, to develop and commercialize cilta-cel (the Janssen Agreement).

Second Quarter 2024 Financial Results

•License Revenue: License revenue was $90.8 million for the three months ended June 30, 2024 compared to $15.1 million for the three months ended June 30, 2023. The increase was primarily driven by a $60.0 million increase in revenue that was recognized due to the nature of and timing of milestones achieved as outlined in the Global Development Plan under the Janssen Agreement for cilta-cel. Additionally, the increase in license revenue is driven by the recognition of $15.7 million of revenue due to the timing of underlying activities performed in connection with the global license agreement with Novartis Pharma AG (the "Novartis License Agreement") to develop, manufacture, and commercialize LB2102 and other potential CAR-T therapies selectively targeting DLL3. Legend Biotech did not recognize any license revenue from the Novartis License Agreement for the three months ended June 30, 2023.

•Collaboration Revenue: Collaboration revenue was $93.3 million for the three months ended June 30, 2024 compared to $58.2 million for the three months ended June 30, 2023. The increase was primarily due to an increase in revenue generated from sales of CARVYKTI® in connection with the Janssen Agreement.

•Collaboration Cost of Revenue: Collaboration cost of revenue was $45.4 million for the three months ended June 30, 2024 compared to $32.7 million for the three months ended June 30, 2023. The increase was primarily due to Legend Biotech’s share of the cost of sales in connection with CARVYKTI® sales under the Janssen Agreement.

•Cost of License and Other Revenue: Cost of license and other revenue for the three months ended June 30, 2024 was $5.1 million and consisted of costs in connection with the Novartis License Agreement. The Company did not incur any cost of license and other revenue for the three months ended June 30, 2023.

•Research and Development Expenses: Research and development expenses were $112.6 million for the three months ended June 30, 2024 compared to $95.8 million for the three months ended June 30, 2023. The increase was primarily driven by continuous research and development activities in cilta-cel, including start up costs for clinical production in Belgium and continued investment in Legend Biotech’s solid tumor programs.

•Administrative Expenses: Administrative expenses were $35.4 million for the three months ended June 30, 2024 compared to $27.8 million for the three months ended June 30, 2023. The increase was primarily due to the expansion of administrative functions and infrastructure to increase manufacturing capacity.

•Selling and Distribution Expenses: Selling and distribution expenses were $30.1 million for the three months ended June 30, 2024 compared to $21.4 million for the three months ended June 30, 2023.The increase was primarily driven by costs associated with commercial activities for cilta-cel, including the expansion of the sales force and second line indication launch preparation.

•Net Loss: Net loss was $18.2 million for the three months ended June 30, 2024, compared to a net loss of $199.1 million for the three months ended June 30, 2023.

•Cash Position: Cash and cash equivalents, time deposits, and short-term investments were $1.3 billion as of June 30, 2024.

Webcast/Conference Call Details:

Legend Biotech will host its quarterly earnings call and webcast today at 8:00am ET. To access the webcast, please visit this weblink.

A replay of the webcast will be available on Legend Biotech’s website at https://investors.legendbiotech.com/events-and-presentations.

About Legend Biotech

Legend Biotech is a global biotechnology company dedicated to treating, and one day curing, life-threatening diseases. Headquartered in Somerset, New Jersey, we are developing advanced cell therapies across a diverse array of technology platforms, including autologous and allogeneic chimeric antigen receptor T-cell, gamma-delta T cell and natural killer (NK) cell-based immunotherapy. From our three R&D sites around the world, we apply these innovative technologies to pursue the discovery of cutting-edge therapeutics for patients worldwide.

Learn more at https://legendbiotech.com/ and follow us on X (formerly Twitter) and LinkedIn.

CAUTIONARY NOTE REGARDING FORWARD-LOOKING STATEMENTS

Statements in this press release about future expectations, plans, and prospects, as well as any other statements regarding matters that are not historical facts, constitute “forward-looking statements” within the meaning of The Private Securities Litigation Reform Act of 1995. These statements include, but are not limited to, statements relating to Legend Biotech’s strategies and objectives; statements relating to CARVYKTI®, including Legend Biotech’s expectations for CARVYKTI® and its therapeutic potential; statements relating to the potential approval of CARVYKTI® for earlier lines of therapy; statements related to Legend Biotech manufacturing expectations for CARVYKTI®; statements related to Legend Biotech’s ability to achieve operating profit; and the potential benefits of Legend Biotech’s product candidates. The words “anticipate,” “believe,” “continue,” “could,” “estimate,” “expect,” “intend,” “may,” “plan,” “potential,” “predict,” “project,” “should,” “target,” “will,” “would” and similar expressions are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. Actual results may differ materially from those indicated by such forward-looking statements as a result of various important factors. Legend Biotech’s expectations could be affected by, among other things, uncertainties involved in the development of new pharmaceutical products; unexpected clinical trial results, including as a result of additional analysis of existing clinical data or unexpected new clinical data; unexpected regulatory actions or delays, including requests for additional safety and/or efficacy data or analysis of data, or government regulation generally; unexpected delays as a result of actions undertaken, or failures to act, by our third party partners; uncertainties arising from challenges to Legend Biotech’s patent or other proprietary intellectual property protection, including the uncertainties involved in the U.S. litigation process; government, industry, and general product pricing and other political pressures; as well as the other factors discussed in the “Risk Factors” section of Legend Biotech’s Annual Report on Form 20-F filed with the Securities and Exchange Commission on March 19, 2024. Should one or more of these risks or uncertainties materialize, or should underlying assumptions prove incorrect, actual results may vary materially from those described in this press release as anticipated, believed, estimated or expected. Any forward-looking statements contained in this press release speak only as of the date of this press release. Legend Biotech specifically disclaims any obligation to update any forward-looking statement, whether as a result of new information, future events or otherwise.

INVESTOR CONTACT:

Jessie Yeung

Tel: (732) 956-8271

jessie.yeung@legendbiotech.com

PRESS CONTACT:

Mary Ann Ondish

Tel: (914) 552-4625

media@legendbiotech.com

LEGEND BIOTECH CORPORATION

CONDENSED CONSOLIDATED STATEMENTS OF PROFIT OR LOSS


	Three Months Ended June 30, 2024		Six Months Ended June 30, 2024
	2024	2023	2024	2023
US$’000, except share and per share data	(Unaudited)	(Unaudited)	(Unaudited)	(Unaudited)
REVENUE
License revenue	90,846	15,115	103,027	15,115
Collaboration revenue	93,254	58,152	171,735	94,432
Other revenue	2,423	63	5,752	119
Total revenue	186,523	73,330	280,514	109,666
Collaboration cost of revenue	(45,355)	(32,672)	(94,456)	(68,285)
Cost of license and other revenue	(5,096)	—	(10,734)	—
Other income and gains	29,484	16,433	93,037	20,994
Research and development expenses	(112,626)	(95,791)	(213,590)	(180,680)
Administrative expenses	(35,353)	(27,753)	(67,282)	(49,958)
Selling and distribution expenses	(30,063)	(21,429)	(54,286)	(39,383)
Other expenses	—	(21)	(2)	(7,117)
Fair value loss of warrant liability	—	(105,750)	—	(85,750)
Finance costs	(5,484)	(5,185)	(10,959)	(10,298)
LOSS BEFORE TAX	(17,970)	(198,838)	(77,758)	(310,811)
Income tax expense	(226)	(290)	(231)	(418)
LOSS FOR THE PERIOD	(18,196)	(199,128)	(77,989)	(311,229)
Attributable to:
Ordinary equity holders of the parent	(18,196)	(199,128)	(77,989)	(311,229)
LOSS PER SHARE ATTRIBUTABLE TO ORDINARY EQUITY HOLDERS OF THE PARENT
Basic	(0.05)	(0.57)	(0.21)	(0.91)
Diluted	(0.05)	(0.57)	(0.21)	(0.91)
ORDINARY SHARES USED IN LOSS PER SHARE COMPUTATION
Basic	365,204,154	350,517,429	364,610,589	340,779,779
Diluted	365,204,154	350,517,429	364,610,589	340,779,779

LEGEND BIOTECH CORPORATION

CONDENSED CONSOLIDATED STATEMENTS OF FINANCIAL POSITION


	June 30, 2024	December 31, 2023
	US$’000	US$’000
	(Unaudited)
NON-CURRENT ASSETS
Property, plant and equipment	105,018	108,725
Advance payments for property, plant and equipment	295	451
Right-of-use assets	114,718	80,502
Time deposits	4,400	4,362
Intangible assets	2,772	4,061
Collaboration prepaid leases	144,552	151,216
Other non-current assets	1,596	1,493
Total non-current assets	373,351	350,810
CURRENT ASSETS
Collaboration inventories	18,870	19,433
Trade receivables	13,064	100,041
Prepayments, other receivables and other assets	100,628	69,251
Financial assets at fair value through profit or loss	42,201	663
Pledged deposits	431	357
Time deposits	1,048,385	30,341
Cash and cash equivalents	201,253	1,277,713
Total current assets	1,424,832	1,497,799
Total assets	1,798,183	1,848,609
CURRENT LIABILITIES
Trade payables	39,490	20,160
Other payables and accruals	169,531	132,802
Government grants	545	68
Lease liabilities	3,325	3,175
Tax payable	6,566	7,203
Contract liabilities	74,845	53,010
Total current liabilities	294,302	216,418
NON-CURRENT LIABILITIES
Collaboration interest-bearing advanced funding	291,559	281,328
Lease liabilities long term	44,042	44,169
Government grants	6,574	7,305
Contract liabilities	2,704	47,962
Other non-current liabilities	—	56
Total non-current liabilities	344,879	380,820
Total liabilities	639,181	597,238
EQUITY
Share capital	37	36
Reserves	1,158,965	1,251,335
Total ordinary shareholders’ equity	1,159,002	1,251,371
Total equity	1,159,002	1,251,371
Total liabilities and equity	1,798,183	1,848,609

LEGEND BIOTECH CORPORATION

CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOW


	Three Months Ended June 30,		Six Months Ended June 30,
US$’000	2024	2023	2024	2023
	(Unaudited)	(Unaudited)	(Unaudited)	(Unaudited)

LOSS BEFORE TAX	(17,970)	(198,838)	(77,758)	(310,811)
CASH FLOWS (USED IN)/PROVIDED BY OPERATING ACTIVITIES	(1,651)	(95,730)	13,867	(236,783)
CASH FLOWS USED IN INVESTING ACTIVITIES	(695,631)	(123,581)	(1,091,779)	(105,651)
CASH FLOWS PROVIDED BY FINANCING ACTIVITIES	955	789,890	1,786	789,604
NET (DECREASE)/INCREASE IN CASH AND CASH EQUIVALENTS	(696,327)	570,579	(1,076,126)	447,170
Effect of foreign exchange rate changes, net	9	2,584	(334)	12
Cash and cash equivalents at beginning of the period	897,571	660,050	1,277,713	786,031

CASH AND CASH EQUIVALENTS AT END OF THE PERIOD	201,253	1,233,213	201,253	1,233,213
ANALYSIS OF BALANCES OF CASH AND CASH EQUIVALENTS
Cash and bank balances	1,254,469	1,334,482	1,254,469	1,334,482
Less: Pledged deposits	431	1,246	431	1,246
Time deposits	1,052,785	100,023	1,052,785	100,023
Cash and cash equivalents as stated in the statement of financial position	201,253	1,233,213	201,253	1,233,213
Cash and cash equivalents as stated in the statement of cash flows	201,253	1,233,213	201,253	1,233,213

1 This presentation is for investor relations purposes only - Not for product promotional purposes Our Pipeline *In collaboration with Janssen, Pharmaceutical Companies of Johnson & Johnson. †Phase 1 investigator-initiated trial in China. ‡IND applications have been cleared by the U.S. FDA. #Subject to an exclusive license agreement with Novartis Pharma AG. The safety and efficacy of the agents and/or uses under investigation have not been established. There is no assurance that the agents will receive health authority approval or become commercially available in any country for the uses being investigated. Additionally, as some programs are still confidential, certain candidates may not be included in this list. INDICATIONS: ALL: acute lymphoblastic leukemia; LCNEC: large cell neuroendocrine carcinoma; MM: multiple myeloma; NDMM: newly diagnosed multiple myeloma; NHL: non-Hodgkin lymphoma; RRMM: relapsed or refractory multiple myeloma; SCLC: small cell lung cancer TARGETS: BCMA: B-cell maturation antigen; DLL3: delta-like ligand 3; GCC: guanylyl cyclase C; GPRC5D: G-protein coupled receptor, family C, group 5, member D Global US China Autologous Therapies BCMA-directed autologous therapy * P H A S E 2 P H A S E 3 LEGEND-2† RRMM NCT03090659 CARTIFAN-1* RRMM NCT03758417 CARTITUDE-1* RRMM NCT03548207 CARTITUDE-2* MM NCT04133636 CARTITUDE-4* RRMM 1-3 Prior Lines NCT04181827 CARTITUDE-5* NDMM Transplant Not Intended NCT04923893 CARTITUDE-6* NDMM Transplant Eligible NCT05257083 Cilta-cel Clinical Studies P H A S E 1 P R E C L I N I C A L P H A S E 1 NHL† /ALL† (CD19 X CD20 X CD22)† GASTRIC & PANCREATIC‡ (CLAUDIN 18.2) SCLC & LCNEC‡# (DLL3) COLORECTAL† (GCC) Additional Pipeline Assets Allogeneic Therapies MM† (BCMA) CAR-γδ T NHL† (CD19 X CD20) CAR-γδ T NHL† (CD20) CAR-αβ T MM† (BCMA) CAR-NK MM † (CD19 X GPRC5D), (GPRC5D) AUTOIMMUNE (CD19 X CD20 X CD22) AUTOIMMUNE (CD19 X BCMA)

COVER	6 Months Ended
COVER	Jun. 30, 2024
Cover [Abstract]
Document Type	6-K
Entity Registrant Name	Legend Biotech Corporation
Entity Central Index Key	0001801198
Document Period End Date	Jun. 30, 2024
Document Fiscal Year Focus	2024
Document Fiscal Period Focus	Q2
Current Fiscal Year End Date	--12-31
Amendment Flag	false

UNAUDITED INTERIM CONDENSED CONSOLIDATED STATEMENTS OF PROFIT OR LOSS AND OTHER COMPREHENSIVE INCOME - USD ($) $ in Thousands	6 Months Ended
	Jun. 30, 2024	Jun. 30, 2023
REVENUE
License revenue	$ 103,027	$ 15,115
Collaboration revenue	171,735	94,432
Other revenue	5,752	119
Total revenue	280,514	109,666
Collaboration cost of revenue	(94,456)	(68,285)
Cost of license and other revenue	(10,734)	0
Other income and gains	93,037	20,994
Research and development expenses	(213,590)	(180,680)
Administrative expenses	(67,282)	(49,958)
Selling and distribution expenses	(54,286)	(39,383)
Other expenses	(2)	(7,117)
Fair value loss of warrant liability	0	(85,750)
Finance costs	(10,959)	(10,298)
LOSS BEFORE TAX	(77,758)	(310,811)
Income tax expense	(231)	(418)
LOSS FOR THE PERIOD	(77,989)	(311,229)
Attributable to:
Ordinary equity holders of the parent	$ (77,989)	$ (311,229)
LOSS PER SHARE ATTRIBUTABLE TO ORDINARY EQUITY HOLDERS OF THE PARENT
Basic (in dollars per share)	$ (0.21)	$ (0.91)
Diluted (in dollars per share)	$ (0.21)	$ (0.91)
OTHER COMPREHENSIVE (LOSS)/ INCOME
Exchange differences on translation of foreign operations	$ (58,528)	$ 6,537
Net other comprehensive (loss)/ income that may be reclassified to profit or loss in subsequent periods	(58,528)	6,537
OTHER COMPREHENSIVE (LOSS)/ INCOME FOR THE PERIOD, NET OF TAX	(58,528)	6,537
TOTAL COMPREHENSIVE LOSS FOR THE PERIOD	(136,517)	(304,692)
Attributable to:
Ordinary equity holders of the parent	$ (136,517)	$ (304,692)

UNAUDITED INTERIM CONDENSED CONSOLIDATED STATEMENTS OF FINANCIAL POSITION - USD ($) $ in Thousands	Jun. 30, 2024	Dec. 31, 2023
NON-CURRENT ASSETS
Property, plant and equipment	$ 105,018	$ 108,725
Advance payments for property, plant and equipment	295	451
Right-of-use assets	114,718	80,502
Time deposits	4,400	4,362
Intangible assets	2,772	4,061
Collaboration prepaid leases	144,552	151,216
Other non-current assets	1,596	1,493
Total non-current assets	373,351	350,810
CURRENT ASSETS
Collaboration inventories	18,870	19,433
Trade receivables	13,064	100,041
Prepayments, other receivables and other assets	100,628	69,251
Financial assets at fair value through profit or loss	42,201	663
Pledged deposits	431	357
Time deposits	1,048,385	30,341
Cash and cash equivalents	201,253	1,277,713
Total current assets	1,424,832	1,497,799
Total assets	1,798,183	1,848,609
CURRENT LIABILITIES
Trade payables	39,490	20,160
Other payables and accruals	169,531	132,802
Government grants	545	68
Lease liabilities	3,325	3,175
Tax payable	6,566	7,203
Contract liabilities	74,845	53,010
Total current liabilities	294,302	216,418
NON-CURRENT LIABILITIES
Collaboration interest-bearing advanced funding	291,559	281,328
Lease liabilities long term	44,042	44,169
Government grants	6,574	7,305
Contract liabilities	2,704	47,962
Other non-current liabilities	0	56
Total non-current liabilities	344,879	380,820
Total liabilities	639,181	597,238
EQUITY
Share capital	37	36
Reserves	1,158,965	1,251,335
Total ordinary shareholders’ equity	1,159,002	1,251,371
Total equity	1,159,002	1,251,371
Total liabilities and equity	$ 1,798,183	$ 1,848,609

UNAUDITED INTERIM CONDENSED CONSOLIDATED STATEMENTS OF CHANGES IN EQUITY - USD ($)
$ in Thousands

Total

Private Placement For Institutional Investors

Registered Direct Offering

Exercise of Warrant

Share capital

Private Placement For Institutional Investors

Share capital

Registered Direct Offering

Share capital

Exercise of Warrant

Share premium

^[1]

Share premium

Private Placement For Institutional Investors

^[1]

Share premium

Registered Direct Offering

^[1]

Share premium

Exercise of Warrant

^[1]

Share-based compensation reserves

^[1]

Foreign currency translation reserve

^[1]

Retained earnings/(accumulated losses)

^[1]

Beginning balance at Dec. 31, 2022

$ 744,312

$ 33

$ 1,657,015

$ 39,049

$ 14,671

$ (966,456)

Statement of changes in equity [Roll Forward]

Loss for the period

(311,229)

Other comprehensive loss:

Exchange differences on translation of foreign operations

6,537

TOTAL COMPREHENSIVE LOSS FOR THE PERIOD

(304,692)

6,537

(311,229)

Issuance of ordinary shares

$ 234,410

$ 349,278

$ 352,491

$ 1

$ 234,409

$ 349,277

$ 352,490

Exercise of share options

8,518

13,072

(4,554)

Reclassification of vested restricted share units

18,606

(18,606)

Equity-settled share-based compensation expense

22,714

Ending balance at Jun. 30, 2023

1,407,031

2,624,869

38,603

21,208

(1,277,685)

Other comprehensive loss:

Reserves

1,407,000

Reserves

1,251,335

Beginning balance at Dec. 31, 2023

1,251,371

2,637,120

54,621

44,304

(1,484,710)

Statement of changes in equity [Roll Forward]

Loss for the period

(77,989)

Other comprehensive loss:

Exchange differences on translation of foreign operations

(58,528)

TOTAL COMPREHENSIVE LOSS FOR THE PERIOD

(136,517)

(58,528)

(77,989)

Exercise of share options

3,705

5,548

(1,843)

Reclassification of vested restricted share units

32,547

(32,547)

Equity-settled share-based compensation expense

40,442

Ending balance at Jun. 30, 2024

1,159,002

$ 37

$ 2,675,215

$ 60,673

$ (14,224)

$ (1,562,699)

Other comprehensive loss:

Reserves

$ 1,158,965

[1]	These reserve accounts comprise the consolidated reserves of $1,159.0 million and $1,407.0 million in the consolidated statements of financial position as at June 30, 2024 and, 2023, respectively

UNAUDITED INTERIM CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands	6 Months Ended
	Jun. 30, 2024	Jun. 30, 2023
CASH FLOWS PROVIDED BY/ (USED IN), OPERATING ACTIVITIES
Loss before tax	$ (77,758)	$ (310,811)
Adjustments for:
Finance income	(30,919)	(18,765)
Finance costs	10,959	10,298
Provision for inventory reserve	6,425	577
Depreciation of property, plant and equipment	5,576	5,303
Loss on disposal of property, plant and equipment	2	141
Amortization of intangible assets	1,251	943
Depreciation of right-of-use assets	4,264	3,683
Fair value loss of warrant liability	0	85,750
Fair value gains on financial assets measured at fair value through profit or loss	(201)	(756)
Increase in contract liabilities (current)	23,708	0
Decrease in contract liabilities (non-current)	(44,175)	0
Foreign currency exchange (gain)/loss, net	(60,704)	7,020
Equity-settled share-based compensation expense	40,442	22,714
Deferred government grant	(293)	(360)
Cash flows provided by (used in) operations before changes in working capital	(121,423)	(194,263)
Decrease/(increase) in trade receivables	86,977	(14,974)
Increase in prepayments, other receivables and other assets	(30,341)	(6,514)
Increase in other non-current assets	(112)	0
Increase in collaboration inventories	(5,862)	(5,419)
Government grant received	85	0
Increase/(decrease) in trade payables	19,285	(11,349)
Increase/(decrease) in other payables and accruals	47,686	(20,263)
Decrease in other non-current liabilities	(56)	(14)
Increase in pledged deposits, net	(71)	0
Cash used in operations	(3,832)	(252,796)
Interest income received	19,285	16,622
Income tax paid	(847)	0
Interest on lease payments	(739)	(609)
Net cash provided by/(used in) operating activities	13,867	(236,783)
CASH FLOWS USED IN INVESTING ACTIVITIES
Purchase of property, plant and equipment	(9,662)	(10,362)
Purchase of intangible assets	0	(38)
Prepayment to collaborator for collaboration assets	(33,695)	(53,018)
Purchase of financial assets measured at fair value through profit or loss	(150,560)	0
Cash receipts of investment income	1,846	4,037
Cash received from withdrawal of financial assets measured at fair value through profit or loss	108,163	0
Addition in time deposits	(2,194,188)	(432,023)
Decrease in time deposits	1,186,317	385,753
Net cash used in investing activities	(1,091,779)	(105,651)
CASH FLOWS FROM FINANCING ACTIVITIES
Proceeds from registered direct offering, net of issuance costs	0	349,278
Proceeds from exercise of warrant by warrant holder, net of issuance cost	0	199,741
Proceeds from issuance of ordinary shares for follow on public offering, net of issuance costs	0	234,410
Proceeds from exercise of share options	3,704	8,513
Principal portion of lease payments	(1,918)	(2,338)
Net cash provided by financing activities	1,786	789,604
NET (DECREASE)/ INCREASE IN CASH AND CASH EQUIVALENTS	(1,076,126)	447,170
Effect of foreign exchange rate changes, net	(334)	12
Cash and cash equivalents at beginning of year	1,277,713	786,031
CASH AND CASH EQUIVALENTS AT END OF PERIOD	201,253	1,233,213
ANALYSIS OF BALANCES OF CASH AND CASH EQUIVALENTS
Cash and bank balances	1,254,469	1,334,482
Less: Pledged deposits	431	1,246
Time deposits	1,052,785	100,023
Cash and cash equivalents as stated in the statement of financial position	201,253	1,233,213
Cash and cash equivalents as stated in the statement of cash flows	$ 201,253	$ 1,233,213

CORPORATE INFORMATION	6 Months Ended
CORPORATE INFORMATION	Jun. 30, 2024
Disclosure of subsidiaries [abstract]
CORPORATE INFORMATION	CORPORATE INFORMATION Legend Biotech Corporation, (the "Company"), was incorporated on May 27, 2015 as an exempted company in the Cayman Islands with limited liability under the Companies Act (As Revised) of the Cayman Islands. The registered office address of the Company is PO Box 10240, Harbour Place, 103 South Church Street, George Town, Grant Cayman KY1-1002, Cayman Islands. Legend Biotech Corporation is an investment holding company. The Company’s subsidiaries are principally engaged in the discovery, development, manufacturing and commercialization of novel cell therapies for oncology and other indications.

BASIS OF PREPARATION	6 Months Ended
BASIS OF PREPARATION	Jun. 30, 2024
Basis of Preparation [Abstract]
BASIS OF PREPARATION	BASIS OF PREPARATION The unaudited interim condensed consolidated financial statements of Legend and its subsidiaries (collectively referred to as the “Company”) for the six months ended June 30, 2024 have been prepared in accordance with International Accounting Standard (“IAS”) 34 Interim Financial Reporting (“IAS34”) issued by the International Accounting Standards Board (the “IASB”). The accounting policies and basis of preparation adopted in the preparation of these unaudited interim condensed consolidated financial statements are consistent with those followed in the preparation of the Company financial statements for the year ended December 31, 2023. The Company has not early adopted any other standards, interpretation or amendments that have been issued but are not yet effective. In the opinion of the Company’s management, the accompanying unaudited interim condensed consolidated financial statements contain all normal recurring adjustments necessary to present fairly the financial position, operating results and cash flows of the Company for each of the periods presented. The results of operations for the six months ended June 30, 2024 are not necessarily indicative of results to be expected for any other interim periods or for the year ended December 31, 2023. The condensed consolidated statement of financial position as of December 31, 2023 was derived from the audited consolidated financial statements at that date but does not include all of the disclosures required by the IASB for annual financial statements. These unaudited interim condensed consolidated financial statements should be read in conjunction with the Company’s audited consolidated financial statements for the year ended December 31, 2023.

NEW STANDARDS, INTERPRETATIONS AND AMENDMENTS ADOPTED BY THE COMPANY	6 Months Ended
	Jun. 30, 2024
Disclosure of expected impact of initial application of new standards or interpretations [abstract]
NEW STANDARDS, INTERPRETATIONS AND AMENDMENTS ADOPTED BY THE COMPANY	NEW STANDARDS, INTERPRETATIONS AND AMENDMENTS ADOPTED BY THE COMPANY There were no new International Financial Reporting Standards (“IFRS”), amendments or interpretations issued by the IASB that became effective in the six months ended June 30, 2024 that had a material impact on the Company's unaudited interim condensed consolidated financial statements.

REVENUE, OTHER INCOME AND GAINS

6 Months Ended

Jun. 30, 2024

Disclosure of disaggregation of revenue from contracts with customers [abstract]

REVENUE, OTHER INCOME AND GAINS

An analysis of revenue is as follows:


	Six months ended June 30,
	2024	2023
	US$’000 (Unaudited)	US$’000 (Unaudited)
Revenue
License revenue	103,027	15,115
Collaboration revenue	171,735	94,432
Other revenue	5,752	119
Total	280,514	109,666

Janssen Collaboration Agreement

Collaboration revenue includes our pro-rata share of collaboration net trade sales for which Janssen is the principal in the sale to the customer under the Janssen Agreement.

Novartis License Agreement

Other Revenue

Other revenue primarily includes supply of materials by us to Novartis under the terms of the Novartis License Agreement.

The following table shows the deferred revenue which is included in contract liabilities for the periods presented:


	June 30,	December 31
	2024	2023
	US$’000 (Unaudited)	US$’000
Contract liabilities (Current)	74,845	53,010
Contract liabilities (Non-Current)	2,704	47,962
Total	77,549	100,972

The following table summarizes the Total other income and gains:


	Six months ended June 30,
	2024	2023
	US$’000 (Unaudited)	US$’000 (Unaudited)
Other income and gains
Other income:
Finance income	30,919	18,765
Government grants*	1,036	1,352
Other	156	4
Total income	32,111	20,121

Gains:
Foreign currency exchange gain, net	60,704	—
Fair value gains on financial assets measured at fair value change through profit or loss	201	756
Other	21	117
Total gains	60,926	873
Total other income and gains	93,037	20,994

FINANCE COSTS

6 Months Ended

Jun. 30, 2024

Finance Costs [Abstract]

FINANCE COSTS


	Six months ended June 30,
	2024	2023
	US$’000 (Unaudited)	US$’000 (Unaudited)
Interest on lease liabilities	739	609
Collaboration interest-bearing advanced funding	10,220	9,689
Total	10,959	10,298

LOSS PER SHARE ATTRIBUTABLE TO ORDINARY EQUITY HOLDERS OF THE PARENT

6 Months Ended

Jun. 30, 2024

Basic earnings per share [abstract]

LOSS PER SHARE ATTRIBUTABLE TO ORDINARY EQUITY HOLDERS OF THE PARENT

The calculations of basic and diluted loss per share are based on:


	Six months ended June 30,
	2024	2023
	US$’000 (Unaudited)	US$’000 (Unaudited)
Losses
Loss attributable to ordinary equity holders of the parent, used in the basic earnings per share calculation	(77,989)	(311,229)


	Number of shares Six months ended June 30,
	2024	2023
	(Unaudited)	(Unaudited)
Shares
Weighted average number of ordinary shares in issue during the period used in the basic earnings per share calculation	364,610,589	340,779,779

PROPERTY, PLANT AND EQUIPMENT

6 Months Ended

Jun. 30, 2024

Disclosure of detailed information about property, plant and equipment [abstract]

PROPERTY, PLANT AND EQUIPMENT

The carrying amounts of the Company’s property, plant and equipment and the movements for the six months ended June 30, 2024 are as follows:


						2024
						US$’000 (Unaudited)
At January 1, 2024
Cost						143,727
Accumulated depreciation						(35,002)
Net carrying amount						108,725
At January 1, 2024, net of accumulated depreciation						108,725
Additions						3,320
Disposals						(983)
Depreciation provided during the period						(5,576)
Exchange realignment						(468)
At June 30, 2024, net of accumulated depreciation						105,018
At June 30, 2024:
Cost						144,388
Accumulated depreciation						(39,370)
Net carrying amount						105,018

LEASES

6 Months Ended

Jun. 30, 2024

Lease [Abstract]

LEASES

The Company as a lessee

(a)Right-of-use assets

The carrying amounts of the Company’s right-of-use assets and the movements for the six months ended June 30, 2024 are as follows:


						2024
						US$’000 (Unaudited)

Right-of-use assets at January 1, 2024						80,502
Additions						40,215

Exchange realignment						(1,735)
Depreciation of right-of-use assets						(4,264)
Right-of-use assets at June 30, 2024						114,718

(b)Lease liabilities


						2024
						US$’000 (Unaudited)
Carrying amount at January 1, 2024						47,344
Additions						3,266
Accretion of interest recognized during the period						739
Payments						(2,657)
Exchange realignment						(1,325)
Carrying amount at June 30, 2024						47,367
Analyzed into:
Current portion						3,325
Non-current portion						44,042
Total						47,367

COLLABORATION INVENTORIES

6 Months Ended

Jun. 30, 2024

Classes of current inventories [abstract]

COLLABORATION INVENTORIES


	June 30, 2024	December 31, 2023
	US$’000 (Unaudited)	US$’000
Raw materials	14,041	13,155
Work-in-process	4,236	2,990
Finished goods	593	3,288
Total collaboration inventories	18,870	19,433

PREPAYMENTS, OTHER RECEIVABLES AND OTHER ASSETS

6 Months Ended

Jun. 30, 2024

Disclosure Of Prepayments Other Receivables And Other Assets [Abstract]

PREPAYMENTS, OTHER RECEIVABLES AND OTHER ASSETS


	June 30, 2024	December 31, 2023
	US$’000 (Unaudited)	US$’000

Other collaboration receivables	83,860	54,078

Other receivables	1,870	837
Lease receivables	344	1,388
VAT recoverable	2,237	717
Prepayments	12,317	12,231
Total	100,628	69,251

CASH AND CASH EQUIVALENTS, TIME DEPOSITS AND PLEDGED DEPOSITS

6 Months Ended

Jun. 30, 2024

Disclosure Of Cash And Cash Equivalents Time Deposits And Pledged Deposits [Abstract]

CASH AND CASH EQUIVALENTS, TIME DEPOSITS AND PLEDGED DEPOSITS


	June 30, 2024	December 31, 2023
	US$’000 (Unaudited)	US$’000

Cash and bank balances	1,254,469	1,312,773
Less: Pledged deposits	(431)	(357)
Time deposits	(1,052,785)	(34,703)

Cash and cash equivalents	201,253	1,277,713

Denominated in USD	178,793	1,254,969
Denominated in RMB	17,205	12,675
Denominated in EUR	5,255	10,069

Cash and cash equivalents	201,253	1,277,713

The pledged deposit as at June 30, 2024 was primarily pledged for office space and credit card facilities, while the pledged deposit as at December 31, 2023 was pledged for credit card facilities.

OTHER PAYABLES AND ACCRUALS

6 Months Ended

Jun. 30, 2024

Disclosure Of Other Payables And Accruals [Abstract]

OTHER PAYABLES AND ACCRUALS


	June 30, 2024	December 31, 2023
	US$’000 (Unaudited)	US$’000
Accrued payroll	22,450	30,974
Accrued expense	108,205	71,462
Other payables	21,681	11,944
Payable for collaboration assets	15,350	16,338
Other tax payables	1,845	2,084
Total	169,531	132,802

Other payables are non-interest-bearing and repayable on demand.

COLLABORATION INTEREST-BEARING ADVANCED FUNDING

6 Months Ended

Jun. 30, 2024

Disclosure of detailed information about borrowings [abstract]

COLLABORATION INTEREST-BEARING ADVANCED FUNDING

Effective interest rate (%)

Maturity

June 30,
2024

US$’000
(Unaudited)

Non-current

Loans from a collaborator

8.26

No specific maturity date

291,559

SHARE CAPITAL AND SHARE PREMIUM

6 Months Ended

Jun. 30, 2024

Disclosure of classes of share capital [abstract]

SHARE CAPITAL AND SHARE PREMIUM


	June 30, 2024	December 31, 2023
	US$’000 (Unaudited)	US$’000
Authorized:
2,000,000,000 ordinary shares of $0.0001 each	200	200
Issued and fully paid:
366,341,403 and (2023: 363,822,069) ordinary shares of $0.0001 each	37	36

A summary of movements in the Company’s share capital and share premium is as follows:


	Number of shares in issue	Share capital	Share premium	Total
		US$’000	US$’000	US$’000
At December 31, 2023 and January 1, 2024	363,822,069	36	2,637,120	2,637,156
Exercise of share options	1,045,392	—	5,548	5,548
Reclassification of vesting of restricted share units	1,473,942	1	32,547	32,548
At June 30, 2024 (Unaudited)	366,341,403	37	2,675,215	2,675,252

FAIR VALUE AND FAIR VALUE HIERARCHY OF FINANCIAL INSTRUMENTS

6 Months Ended

Jun. 30, 2024

Disclosure Of Fair Value Of Financial Instruments [Abstract]

FAIR VALUE AND FAIR VALUE HIERARCHY OF FINANCIAL INSTRUMENTS

The following table illustrates the fair value measurement hierarchy of the Company’s financial instruments:

Asset measured at fair value:

As at June 30, 2024 (Unaudited)

Fair value measurement using

Quoted
prices
in active
markets
(Level 1)

Significant
observable
inputs
(Level 2)

Significant
unobservable
inputs
(Level 3)

Total

US$’000

Financial assets at fair value through profit or loss

42,201

—

42,201

As at December 31, 2023

Fair value measurement using

Quoted
prices
in active
markets
(Level 1)

Significant
observable
inputs
(Level 2)

Significant
unobservable
inputs
(Level 3)

Total

US$’000

Financial assets at fair value through profit or loss

663

—

663

Financial assets measured at fair value consists of money market funds.

APPROVAL OF THE INTERIM CONDENSED CONSOLIDATED FINANCIAL STATEMENTS	6 Months Ended
	Jun. 30, 2024
Statement of financial position [abstract]
APPROVAL OF THE INTERIM CONDENSED CONSOLIDATED FINANCIAL STATEMENTS	APPROVAL OF THE INTERIM CONDENSED CONSOLIDATED FINANCIAL STATEMENTS The interim condensed consolidated financial statements were approved and authorized for issue by the Board of Directors on August 8, 2024.

REVENUE, OTHER INCOME AND GAINS (Tables)

6 Months Ended

Jun. 30, 2024

Disclosure of disaggregation of revenue from contracts with customers [abstract]

Summary of Analysis of Revenue

An analysis of revenue is as follows:


	Six months ended June 30,
	2024	2023
	US$’000 (Unaudited)	US$’000 (Unaudited)
Revenue
License revenue	103,027	15,115
Collaboration revenue	171,735	94,432
Other revenue	5,752	119
Total	280,514	109,666

Summary of Deferred Revenue from Contract Liabilities

The following table shows the deferred revenue which is included in contract liabilities for the periods presented:


	June 30,	December 31
	2024	2023
	US$’000 (Unaudited)	US$’000
Contract liabilities (Current)	74,845	53,010
Contract liabilities (Non-Current)	2,704	47,962
Total	77,549	100,972

Other Income and Gains

The following table summarizes the Total other income and gains:


	Six months ended June 30,
	2024	2023
	US$’000 (Unaudited)	US$’000 (Unaudited)
Other income and gains
Other income:
Finance income	30,919	18,765
Government grants*	1,036	1,352
Other	156	4
Total income	32,111	20,121

Gains:
Foreign currency exchange gain, net	60,704	—
Fair value gains on financial assets measured at fair value change through profit or loss	201	756
Other	21	117
Total gains	60,926	873
Total other income and gains	93,037	20,994

FINANCE COSTS (Tables)

6 Months Ended

Jun. 30, 2024

Finance Costs [Abstract]

Summary of Finance Costs


	Six months ended June 30,
	2024	2023
	US$’000 (Unaudited)	US$’000 (Unaudited)
Interest on lease liabilities	739	609
Collaboration interest-bearing advanced funding	10,220	9,689
Total	10,959	10,298

LOSS PER SHARE ATTRIBUTABLE TO ORDINARY EQUITY HOLDERS OF THE PARENT (Tables)

6 Months Ended

Jun. 30, 2024

Basic earnings per share [abstract]

Summary of Calculations of Basic and Diluted Loss per Share

The calculations of basic and diluted loss per share are based on:


	Six months ended June 30,
	2024	2023
	US$’000 (Unaudited)	US$’000 (Unaudited)
Losses
Loss attributable to ordinary equity holders of the parent, used in the basic earnings per share calculation	(77,989)	(311,229)


	Number of shares Six months ended June 30,
	2024	2023
	(Unaudited)	(Unaudited)
Shares
Weighted average number of ordinary shares in issue during the period used in the basic earnings per share calculation	364,610,589	340,779,779

PROPERTY, PLANT AND EQUIPMENT (Tables)

6 Months Ended

Jun. 30, 2024

Disclosure of detailed information about property, plant and equipment [abstract]

Schedule of Property, Plant and Equipment

The carrying amounts of the Company’s property, plant and equipment and the movements for the six months ended June 30, 2024 are as follows:


						2024
						US$’000 (Unaudited)
At January 1, 2024
Cost						143,727
Accumulated depreciation						(35,002)
Net carrying amount						108,725
At January 1, 2024, net of accumulated depreciation						108,725
Additions						3,320
Disposals						(983)
Depreciation provided during the period						(5,576)
Exchange realignment						(468)
At June 30, 2024, net of accumulated depreciation						105,018
At June 30, 2024:
Cost						144,388
Accumulated depreciation						(39,370)
Net carrying amount						105,018

LEASES (Tables)

6 Months Ended

Jun. 30, 2024

Lease [Abstract]

Summary of Carrying Amounts of The Right-of-use Assets and Movements

The carrying amounts of the Company’s right-of-use assets and the movements for the six months ended June 30, 2024 are as follows:


						2024
						US$’000 (Unaudited)

Right-of-use assets at January 1, 2024						80,502
Additions						40,215

Exchange realignment						(1,735)
Depreciation of right-of-use assets						(4,264)
Right-of-use assets at June 30, 2024						114,718

Summary of Lease Liabilities Measured at Present Value of Lease Payments to be Made Over Lease Term

The balance of the Company’s lease liabilities and the movements for the six months ended June 30, 2024 are as follows:


						2024
						US$’000 (Unaudited)
Carrying amount at January 1, 2024						47,344
Additions						3,266
Accretion of interest recognized during the period						739
Payments						(2,657)
Exchange realignment						(1,325)
Carrying amount at June 30, 2024						47,367
Analyzed into:
Current portion						3,325
Non-current portion						44,042
Total						47,367

COLLABORATION INVENTORIES (Tables)

6 Months Ended

Jun. 30, 2024

Classes of current inventories [abstract]

Summary of Inventories


	June 30, 2024	December 31, 2023
	US$’000 (Unaudited)	US$’000
Raw materials	14,041	13,155
Work-in-process	4,236	2,990
Finished goods	593	3,288
Total collaboration inventories	18,870	19,433

PREPAYMENTS, OTHER RECEIVABLES AND OTHER ASSETS (Tables)

6 Months Ended

Jun. 30, 2024

Disclosure Of Prepayments Other Receivables And Other Assets [Abstract]

Summary of Prepayments, Other Receivables and Other Assets


	June 30, 2024	December 31, 2023
	US$’000 (Unaudited)	US$’000

Other collaboration receivables	83,860	54,078

Other receivables	1,870	837
Lease receivables	344	1,388
VAT recoverable	2,237	717
Prepayments	12,317	12,231
Total	100,628	69,251

CASH AND CASH EQUIVALENTS, TIME DEPOSITS AND PLEDGED DEPOSITS (Tables)

6 Months Ended

Jun. 30, 2024

Disclosure Of Cash And Cash Equivalents Time Deposits And Pledged Deposits [Abstract]

Summary of Cash and Cash Equivalents, Time Deposits and Pledged Deposits


	June 30, 2024	December 31, 2023
	US$’000 (Unaudited)	US$’000

Cash and bank balances	1,254,469	1,312,773
Less: Pledged deposits	(431)	(357)
Time deposits	(1,052,785)	(34,703)

Cash and cash equivalents	201,253	1,277,713

Denominated in USD	178,793	1,254,969
Denominated in RMB	17,205	12,675
Denominated in EUR	5,255	10,069

Cash and cash equivalents	201,253	1,277,713

OTHER PAYABLES AND ACCRUALS (Tables)

6 Months Ended

Jun. 30, 2024

Disclosure Of Other Payables And Accruals [Abstract]

Summary of Other Payables and Accruals


	June 30, 2024	December 31, 2023
	US$’000 (Unaudited)	US$’000
Accrued payroll	22,450	30,974
Accrued expense	108,205	71,462
Other payables	21,681	11,944
Payable for collaboration assets	15,350	16,338
Other tax payables	1,845	2,084
Total	169,531	132,802

COLLABORATION INTEREST-BEARING ADVANCED FUNDING (Tables)

6 Months Ended

Jun. 30, 2024

Disclosure of detailed information about borrowings [abstract]

Summary of Interest-Bearing Loans and Borrowings

Effective interest rate (%)

Maturity

June 30,
2024

US$’000
(Unaudited)

Non-current

Loans from a collaborator

8.26

No specific maturity date

291,559

SHARE CAPITAL AND SHARE PREMIUM (Tables)

6 Months Ended

Jun. 30, 2024

Disclosure of classes of share capital [abstract]

Summary of Shares


	June 30, 2024	December 31, 2023
	US$’000 (Unaudited)	US$’000
Authorized:
2,000,000,000 ordinary shares of $0.0001 each	200	200
Issued and fully paid:
366,341,403 and (2023: 363,822,069) ordinary shares of $0.0001 each	37	36

Summary of Movements in the Company's Share Capital and Share Premium

A summary of movements in the Company’s share capital and share premium is as follows:


	Number of shares in issue	Share capital	Share premium	Total
		US$’000	US$’000	US$’000
At December 31, 2023 and January 1, 2024	363,822,069	36	2,637,120	2,637,156
Exercise of share options	1,045,392	—	5,548	5,548
Reclassification of vesting of restricted share units	1,473,942	1	32,547	32,548
At June 30, 2024 (Unaudited)	366,341,403	37	2,675,215	2,675,252

FAIR VALUE AND FAIR VALUE HIERARCHY OF FINANCIAL INSTRUMENTS (Tables)

6 Months Ended

Jun. 30, 2024

Disclosure Of Fair Value Of Financial Instruments [Abstract]

Summary of Assets Measured at Fair Value

Asset measured at fair value:

As at June 30, 2024 (Unaudited)

Fair value measurement using

Quoted
prices
in active
markets
(Level 1)

Significant
observable
inputs
(Level 2)

Significant
unobservable
inputs
(Level 3)

Total

US$’000

Financial assets at fair value through profit or loss

42,201

—

42,201

As at December 31, 2023

Fair value measurement using

Quoted
prices
in active
markets
(Level 1)

Significant
observable
inputs
(Level 2)

Significant
unobservable
inputs
(Level 3)

Total

US$’000

Financial assets at fair value through profit or loss

663

—

663

REVENUE, OTHER INCOME AND GAINS - Summary of Analysis of Revenue (Details) - USD ($) $ in Thousands	6 Months Ended
	Jun. 30, 2024	Jun. 30, 2023
Disclosure of disaggregation of revenue from contracts with customers [abstract]
License revenue	$ 103,027	$ 15,115
Collaboration revenue	171,735	94,432
Other revenue	5,752	119
Total revenue	$ 280,514	$ 109,666

REVENUE, OTHER INCOME AND GAINS - Additional Information (Details) - USD ($) $ in Thousands		6 Months Ended
	Dec. 28, 2023	Jun. 30, 2024	Jun. 30, 2023	Dec. 31, 2023
Disclosure of disaggregation of revenue from contracts with customers [line items]
License revenue		$ 103,027	$ 15,115
Upfront fee receivable		13,064		$ 100,041
Janssen
Disclosure of disaggregation of revenue from contracts with customers [line items]
License revenue		75,100
Novartis
Disclosure of disaggregation of revenue from contracts with customers [line items]
License revenue		$ 27,900
Upfront fee receivable	$ 100,000
Future estimated milestone payments (up to)	$ 1,010,000

REVENUE, OTHER INCOME AND GAINS - Summary of Deferred Revenue (Details) - USD ($) $ in Thousands	Jun. 30, 2024	Dec. 31, 2023
Disclosure of disaggregation of revenue from contracts with customers [abstract]
Contract liabilities (Current)	$ 74,845	$ 53,010
Contract liabilities (Non-Current)	2,704	47,962
Total	$ 77,549	$ 100,972

REVENUE, OTHER INCOME AND GAINS - Other Income and Gains (Details) - USD ($) $ in Thousands	6 Months Ended
	Jun. 30, 2024	Jun. 30, 2023
Other income:
Finance income	$ 30,919	$ 18,765
Government grants	1,036	1,352
Other	156	4
Total income	32,111	20,121
Gains:
Foreign currency exchange gain, net	60,704	0
Fair value gains on financial assets measured at fair value change through profit or loss	201	756
Other	21	117
Total gains	60,926	873
Total other income and gains	$ 93,037	$ 20,994

FINANCE COSTS (Details) - USD ($) $ in Thousands	6 Months Ended
FINANCE COSTS (Details) - USD ($) $ in Thousands	Jun. 30, 2024	Jun. 30, 2023
Finance Costs [Abstract]
Interest on lease liabilities	$ 739	$ 609
Collaboration interest-bearing advanced funding	10,220	9,689
Total	$ 10,959	$ 10,298

LOSS PER SHARE ATTRIBUTABLE TO ORDINARY EQUITY HOLDERS OF THE PARENT - Additional Information (Details) - shares	6 Months Ended
	Jun. 30, 2024	Jun. 30, 2023
Basic earnings per share [abstract]
Weighted average number of ordinary shares in issue (in shares)	364,610,589	340,779,779

LOSS PER SHARE ATTRIBUTABLE TO ORDINARY EQUITY HOLDERS OF THE PARENT - Summary of Calculations of Basic and Diluted Loss per Share (Details) - USD ($) $ in Thousands	6 Months Ended
	Jun. 30, 2024	Jun. 30, 2023
Basic earnings per share [abstract]
Loss attributable to ordinary equity holders of the parent, used in the basic earnings per share calculation	$ (77,989)	$ (311,229)
Weighted average number of ordinary shares in issue during the period used in the basic earnings per share calculation (in shares)	364,610,589	340,779,779

PROPERTY, PLANT AND EQUIPMENT (Details) $ in Thousands	6 Months Ended
PROPERTY, PLANT AND EQUIPMENT (Details) $ in Thousands	Jun. 30, 2024 USD ($)
Property, Plant and Equipment [Roll Forward]
Property, plant and equipment, beginning balance	$ 108,725
Additions	3,320
Disposals	(983)
Depreciation provided during the period	(5,576)
Exchange realignment	(468)
Property, plant and equipment, ending balance	105,018
Cost
Property, Plant and Equipment [Roll Forward]
Property, plant and equipment, beginning balance	143,727
Property, plant and equipment, ending balance	144,388
Accumulated depreciation
Property, Plant and Equipment [Roll Forward]
Property, plant and equipment, beginning balance	(35,002)
Property, plant and equipment, ending balance	$ (39,370)

LEASES - Additional Information (Details) $ in Millions	6 Months Ended
LEASES - Additional Information (Details) $ in Millions	Jun. 30, 2024 USD ($)
Leasehold land
Leases [Line Items]
Lessee, lease terms	50 years
Ongoing lease payments	$ 0.0
Bottom of Range
Leases [Line Items]
Lessee, lease terms	3 years
Top of Range
Leases [Line Items]
Lessee, lease terms	29 years

LEASES - Summary of Carrying Amounts of The Right-of-use Assets and Movements (Details) $ in Thousands	6 Months Ended
	Jun. 30, 2024 USD ($)
Right-of-Use Assets [Roll Forward]
Beginning balance	$ 80,502
Additions	40,215
Exchange realignment	(1,735)
Depreciation of right-of-use assets	(4,264)
Ending balance	$ 114,718

LEASES - Summary of Lease Liabilities Measured at Present Value of Lease Payments to be Made Over Lease Term (Details) - USD ($) $ in Thousands	6 Months Ended
	Jun. 30, 2024	Dec. 31, 2023
Analyzed into:
Current portion	$ 3,325	$ 3,175
Non-current portion	44,042	44,169
Lease liabilities
Leases [Roll Forward]
Beginning balance, carrying amount	47,344
Additions	3,266
Accretion of interest recognized during the period	739
Payments	(2,657)
Exchange realignment	(1,325)
Ending balance, carrying amount	47,367
Analyzed into:
Current portion	3,325
Non-current portion	44,042
Total	$ 47,367	$ 47,344

COLLABORATION INVENTORIES - Summary of Inventories (Details) - USD ($) $ in Thousands	Jun. 30, 2024	Dec. 31, 2023
Classes of current inventories [abstract]
Raw materials	$ 14,041	$ 13,155
Work-in-process	4,236	2,990
Finished goods	593	3,288
Total collaboration inventories	$ 18,870	$ 19,433

COLLABORATION INVENTORIES - Additional Information (Details) - USD ($) $ in Millions	Jun. 30, 2024	Dec. 31, 2023
Classes of current inventories [abstract]
Inventory reserve	$ 15.3	$ 8.9

PREPAYMENTS, OTHER RECEIVABLES AND OTHER ASSETS (Details) - Prepayments Other Receivable and Other Assets - USD ($) $ in Thousands	Jun. 30, 2024	Dec. 31, 2023
Disclosure Of Prepayments Other Receivables And Other Assets [Line Items]
Other collaboration receivables	$ 83,860	$ 54,078
Other receivables	1,870	837
Lease receivables	344	1,388
VAT recoverable	2,237	717
Prepayments	12,317	12,231
Total	$ 100,628	$ 69,251

CASH AND CASH EQUIVALENTS, TIME DEPOSITS AND PLEDGED DEPOSITS - Summary of Cash and Cash Equivalents, Time Deposits and Pledged Deposits (Details) - USD ($) $ in Thousands	Jun. 30, 2024	Dec. 31, 2023	Jun. 30, 2023	Dec. 31, 2022
Disclosure Of Cash And Cash Equivalents Time Deposits And Pledged Deposits [Line Items]
Cash and bank balances	$ 1,254,469	$ 1,312,773
Less: Pledged deposits	(431)	(357)
Time deposits	(1,052,785)	(34,703)
Cash and cash equivalents	201,253	1,277,713	$ 1,233,213	$ 786,031
Denominated in USD
Disclosure Of Cash And Cash Equivalents Time Deposits And Pledged Deposits [Line Items]
Cash and cash equivalents	178,793	1,254,969
Denominated in RMB
Disclosure Of Cash And Cash Equivalents Time Deposits And Pledged Deposits [Line Items]
Cash and cash equivalents	17,205	12,675
Denominated in EUR
Disclosure Of Cash And Cash Equivalents Time Deposits And Pledged Deposits [Line Items]
Cash and cash equivalents	$ 5,255	$ 10,069

CASH AND CASH EQUIVALENTS, TIME DEPOSITS AND PLEDGED DEPOSITS - Additional Information (Details) - USD ($) $ in Thousands	Jun. 30, 2024	Dec. 31, 2023	Jun. 30, 2023	Dec. 31, 2022
Disclosure Of Cash And Cash Equivalents Time Deposits And Pledged Deposits [Line Items]
Cash and cash equivalents	$ 201,253	$ 1,277,713	$ 1,233,213	$ 786,031
Denominated in RMB
Disclosure Of Cash And Cash Equivalents Time Deposits And Pledged Deposits [Line Items]
Cash and cash equivalents	$ 17,205	$ 12,675

OTHER PAYABLES AND ACCRUALS (Details) - USD ($) $ in Thousands	Jun. 30, 2024	Dec. 31, 2023
Disclosure Of Other Payables And Accruals [Abstract]
Accrued payroll	$ 22,450	$ 30,974
Accrued expense	108,205	71,462
Other payables	21,681	11,944
Payable for collaboration assets	15,350	16,338
Other tax payables	1,845	2,084
Total	$ 169,531	$ 132,802

COLLABORATION INTEREST-BEARING ADVANCED FUNDING - Summary of Interest-Bearing Loans and Borrowings (Details) - Interest Bearing Loans $ in Thousands	Jun. 30, 2024 USD ($)
Disclosure Of Detailed Information About Borrowings [Line Items]
Effective interest rate (%)	8.26%
Loans from a collaborator	$ 291,559

COLLABORATION INTEREST-BEARING ADVANCED FUNDING - Additional Information (Details) $ in Millions	6 Months Ended	18 Months Ended
	Jun. 30, 2024 USD ($)	Dec. 16, 2022 USD ($) batch	Sep. 16, 2022 USD ($)	Jun. 17, 2022 USD ($)	Mar. 18, 2022 USD ($)	Dec. 17, 2021 USD ($)	Sep. 17, 2021 USD ($)	Jun. 18, 2021 USD ($)
Disclosure of detailed information about borrowings [abstract]
Funding advances from collaborator principal amount	$ 250.0	$ 3.6	$ 60.5	$ 60.9	$ 5.3	$ 49.3	$ 53.1	$ 17.3
Interest accrued on funding advances	$ 41.6
Interest rate margin percentage	2.50%
Number of batches of funding advances \| batch		7

SHARE CAPITAL AND SHARE PREMIUM - Summary of Shares (Details) - USD ($) $ / shares in Units, $ in Thousands	Jun. 30, 2024	Dec. 31, 2023
Issued and fully paid:
366,341,403 and (2023: 363,822,069) ordinary shares of $0.0001 each	$ 37	$ 36
Ordinary Shares
Authorized:
Ordinary shares authorized (in shares)	2,000,000,000	2,000,000,000
Authorized, price per share (in dollars per share)	$ 0.0001	$ 0.0001
2,000,000,000 ordinary shares of $0.0001 each	$ 200	$ 200
Issued and fully paid:
Ordinary shares issued and fully paid (in shares)	366,341,403	363,822,069
Price per share (in dollars per share)	$ 0.0001	$ 0.0001
366,341,403 and (2023: 363,822,069) ordinary shares of $0.0001 each	$ 37	$ 36

SHARE CAPITAL AND SHARE PREMIUM - Summary of Movements in the Company's Share Capital and Share Premium (Details) $ in Thousands	6 Months Ended
	Jun. 30, 2024 USD ($) shares
Share Capital [Roll Forward]
Beginning balance	$ 2,637,156
Exercise of share options	5,548
Reclassification of vesting of restricted share units	32,548
Ending balance	$ 2,675,252
Number of shares in issue
Share Capital [Roll Forward]
Beginning balance (in shares) \| shares	363,822,069
Exercise of share option (in shares) \| shares	1,045,392
Reclassification of vesting of restricted share units (in shares) \| shares	1,473,942
Ending balance (in shares) \| shares	366,341,403
Share capital
Share Capital [Roll Forward]
Beginning balance	$ 36
Exercise of share options	0
Reclassification of vesting of restricted share units	1
Ending balance	37
Share premium
Share Capital [Roll Forward]
Beginning balance	2,637,120
Exercise of share options	5,548
Reclassification of vesting of restricted share units	32,547
Ending balance	$ 2,675,215

FAIR VALUE AND FAIR VALUE HIERARCHY OF FINANCIAL INSTRUMENTS (Details) - USD ($) $ in Thousands	Jun. 30, 2024	Dec. 31, 2023
Disclosure Fair Value Measurement Hierarchy Of Financial Instruments [Line Items]
Financial assets at fair value through profit or loss	$ 42,201	$ 663
Quoted prices in active markets (Level 1)
Disclosure Fair Value Measurement Hierarchy Of Financial Instruments [Line Items]
Financial assets at fair value through profit or loss	42,201	663
Significant observable inputs (Level 2)
Disclosure Fair Value Measurement Hierarchy Of Financial Instruments [Line Items]
Financial assets at fair value through profit or loss	0	0
Significant unobservable inputs (Level 3)
Disclosure Fair Value Measurement Hierarchy Of Financial Instruments [Line Items]
Financial assets at fair value through profit or loss	$ 0	$ 0

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LEGN Legend Biotech Corporation