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CYX Cytomyx Hldgs

1.10
0.00 (0.00%)
25 Apr 2024 - Closed
Delayed by 15 minutes
Share Name Share Symbol Market Type Share ISIN Share Description
Cytomyx Hldgs LSE:CYX London Ordinary Share GB0033942276 ORD 2.5P
  Price Change % Change Share Price Shares Traded Last Trade
  0.00 0.00% 1.10 0.00 01:00:00
Bid Price Offer Price High Price Low Price Open Price
Industry Sector Turnover Profit EPS - Basic PE Ratio Market Cap
  -
Last Trade Time Trade Type Trade Size Trade Price Currency
- O 0 1.10 GBX

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Date Time Title Posts
01/5/200905:52Cytomyx Holdings! a multi bagger from here144
04/8/200508:22American Buyer Eyeing Cytomyx Holdings51
21/10/200410:24cytomyx set for a sept soar? (200+product launch)602
13/10/200407:41PRODUCT LAUNCH5
26/1/200410:56Cytomex Holdings1

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Posted at 25/1/2007 09:57 by safman
morning..

added CYX to my biotech portfollio, increasing uses of biomarkers in the industry.. one of the aspects, plus dir buying spree..

Do a little research on biomarkers and its increasing uses.. imo

good luck..

saffy..
Posted at 09/1/2007 21:05 by need_love2
Careers

Senior Account Manager
We have an outstanding opportunity for a highly productive Senior Account Manager who can sell our sophisticated line of products and services to all levels of the drug discovery research community. The primary responsibilities of this position will be to consistently meet or exceed assigned territory sales goals through increased market penetration and new business development. Minimum pre-requisites for this position include a BS/MS degree in the Life Sciences (or equivalent) and 5 years of relevant work experience such as 1 to 2 years in the laboratory and 3 plus years selling to research in large pharma, and biotech. The successful candidate will have a demonstrable track record of selling to a sophisticated clientele, outstanding interpersonal and written communication skills, and will professionally represent us to our customers and the drug discovery industry.

We offer a highly competitive compensation packages that include 100% company paid health, dental, and life insurances, a 401(k) plan and paid vacation. This is an excellent opportunity for an outstanding person to join a unique new company on the ground floor, and to grow their career as they share in the success of Cytomyx, LLC.
Posted at 28/11/2006 13:10 by safman
irectorate Change


RNS Number:8283M
Cytomyx Holdings PLC
28 November 2006

CYTOMYX HOLDINGS PLC

("Cytomyx" or the "Company")



New Loan, Board Changes and Appointment of European Distributor



Cytomyx Holdings plc (AIM: CYX), announces that it has entered into a new loan
agreement and the appointment of Cambridge BioScience Limited as its new
European distributor. Several changes to the Board of Directors are also
announced today.



The Company has entered into a new loan agreement which provides the company
with a facility of $266,000. The new lenders are Bioscience Ventures II LP
(Rockville, USA), Cambridge BioScience Limited (Cambridge, UK) and Michael
Kerins, a director of the Company. The new loan has a 2-year term. The Company
has now repaid the outstanding principle of $1,900,000 on a loan to Laurus
Funds.



At a meeting of the Board of directors Dr. Bill Mason (Chairman) and Max Dyer
Bartlett (Finance Director) resigned as directors of the Company. In addition,
Michael Kerins resigned from his position as Chief Executive, but will continue
to serve as a non-executive Director. Glenn Gershon, General Manager of Cytomyx
LLC remains as an Executive Director.



At the meeting Dr. Wei-Wu He was appointed as the new Chairman and Chief
Executive with immediate effect. Dr. He is a General Partner and Co-founder of
Emerging Technology Partners LLC which manages the Biosciences Ventures II fund.
He was also one of the first employees of Human Genome Sciences, Inc. (NSDQ:
HGSI). Dr. He has been involved in over 20 biotech companies through his
career.



The Company also announces today that its operating subsidiary, Cytomyx LLC, has
entered into a new Europe-wide distribution agreement with Cambridge BioScience
Limited. Cambridge BioScience, which was previously a subsidiary of the
Company, is a well established marketing partner for life science technology
companies wishing to build their business in European markets. The initial term
of the appointment is 1 year, which may be extended subject to Cambridge
BioScience achieving certain minimum purchase levels.



Commenting on these developments, Dr. He said; "We are pleased to be able to
provide the Company with this new loan facility, which will be used to provide
short-term working capital. I will be exploring a number of options for the
future development of the Company. Cytomyx LLC is an exciting business with a
unique offering that can be of great value to its clients in the pharmaceutical
industry. The appointment of Cambridge BioScience as our European distributor
will provide us with extended reach into the important European market place. I
would like to thank Dr. Mason and Mr. Dyer-Bartlett for their efforts on behalf
of the Company, during what have at times proved to be challenging
circumstances".





For further information, please contact:
Cytomyx Holdings plc +1 301 222 2200
Dr Wei-Wu He, Chief Executive



Dr Wei-Wu He, aged 41, is currently a director or partner of the following
companies and partnerships:



Emerging Technology Partners
Origene Technologies, Inc.
Intradigm, Inc.
MithraGen, Inc.
Amnis, Inc.



In addition, Dr He has been, within the previous five years, a director or
partner of the following companies and partnerships:


Aptus Pharmaceutical, Inc.
InforMax, Inc
FasGen, Inc.



There is no further information required to be disclosed pursuant to Schedule 2
of the AIM Rules.


This information is provided by RNS
The company news service from the London Stock Exchange
END

BOALVLFLQFBBFBK
Posted at 20/5/2006 23:40 by jweekes
Another director leaves the ship! Is it sinking? The main problem I feel is that they have put all their hopes on the ion screening service, a problem in 3 ways:

1. Competition, and lots of it.

2. Big Pharma want to keep this type of screening in-house if possible.

3. Nearly all clients would need the screening to be performed in FDA-approved labs, wouldn't they? CYX labs are NOT FDA APPROVED are they? Getting approval is expensive and takes ages.

Why would a drug company bother with Cytomyx when the FDA would not even consider their screening results when looking to approve a drug? It has been over a year now since the service was launched and no real customers have been announced. Do they even hold the patents or licence agreements for any of their ion channels (except the Wyeth one)?!!
Posted at 27/4/2006 07:47 by ant15
Im not so certain Price is showing a premarket click up we might need to watch this space.
Posted at 14/3/2006 08:06 by charmer1_23
Disposal of Cytomyx Limited

RNS Number:7465Z
Cytomyx Holdings PLC
14 March 2006


For immediate release 14 March 2006





CYTOMYX HOLDINGS PLC
("Cytomyx" or "the Company")


Disposal of Cytomyx Limited to Serologicals UK for $7 million
Notice of Extraordinary General Meeting

Cytomyx Holdings plc (AIM: CYX.L) today announces the conditional sale of its
subsidiary Cytomyx Limited to Serologicals UK Holding Company Limited
("Serologicals") for $7 million (approximately #4 million) in cash ("the
Disposal"). The proceeds will be reserved for the repayment of outstanding loans
to the Company and used for working capital. Following the Disposal, the Company
will be focussed on the provision to the pharmaceutical industry of high quality
human tissue samples through Cytomyx LLC, its biorepository business based in
Massachusetts in the US. The corporate headquarters of the Company will remain
in the UK, which will also be the focus of the European sales of our
biorepository business.



Highlights



* The Company will sell the entire issued ordinary share capital of
Cytomyx Limited to Serologicals UK for an aggregate cash consideration of $7
million (approximately #4 million), subject to certain adjustments. The
consideration of $7 million is payable in full on completion, of which
approximately $6.2 million (approximately #3.54 million) will be in respect of
the repayment of inter-company debts owed by Cytomyx Limited to the Company and
its other subsidiaries.



* The consideration is subject to an upwards or downwards adjustment on
a pound-for-pound basis to the extent that the working capital of Cytomyx
Limited as at the date of completion is greater or lesser than #21,000. An
adjustment of less than #25,000 upwards or downwards is to be ignored.



* In its unaudited financial statements for the year ended 30 September
2005, Cytomyx Limited reported an operating loss of #867,000 on turnover of
#963,000. As at 30 September 2005, it had net liabilities of #2.79 million.



* With the aim of optimising shareholder value, the Board has been
considering a full range of strategic options for the Company including the sale
of either part or all of the business of Cytomyx Limited. Following a thorough
search for a suitable buyer, for either part or all of the business, the sale of
Cytomyx Limited to Serologicals UK is, in the opinion of the Board, in the best
interests of the Company and its Shareholders as a whole.



* The Company has two loan facilities with Laurus Master Fund Limited ("
Laurus") which, by completion, are expected to total approximately $5.2 million.
The directors expect to use part of the Disposal proceeds to partly pay down the
facility which is based on the level of receivables in order to remain within
the limits of this facility. The directors will then pay an amount equal to the
balance of the principal amount of both Loans to a blocked account as security
for amounts outstanding to Laurus in respect of the Loans. The balance of the
Disposal proceeds, totalling approximately $1.8 million (approximately #1
million), will be used as working capital for the group.



* Following the Disposal, the remaining operating business of the
Company will be Cytomyx LLC, which is based in Lexington, MA., USA. Cytomyx LLC
maintains a large and diverse human tissue biorepository, which contains more
than 140,000 samples, all with extensive associated clinical data. Samples are
bar-coded for tracking purposes and are annotated with associated clinical data
in an on-line database. This collection has been created through supply
agreements with an extensive network of donor sites in the USA.



* Cytomyx LLC is currently working with many of the world's leading
pharmaceutical and biotechnology companies, providing them with samples that
assist them in developing new drugs based upon a clearer understanding of
patients' individual biochemistry. New drugs such as Herceptin, a new treatment
for breast cancer, and Gleevec for the treatment of Chronic Myeloid Leukaemia,
have already demonstrated the value of this approach. We believe that the
prospects for the business to expand in this emerging area are substantial.



* The completion of the Disposal is conditional on the transaction being
approved by the shareholders of the Company. Accordingly a circular has today
been posted to shareholders convening an Extraordinary General Meeting of the
Company, to be held at 11.00 a.m. on 31 March 2006 at 6/7 Technopark, Newmarket
Road, Cambridge, CB5 8PB at which an ordinary resolution seeking shareholder
approval will be considered.

* The Directors of the Company, who hold in aggregate 1,395,000 Ordinary
Shares, representing approximately 2.25% of the issued share capital of the
Company, have undertaken to vote in favour of the ordinary resolution. In
addition the Company has obtained irrevocable undertakings to vote in favour of
the ordinary resolution from Shareholders holding in aggregate 23,677,370
Ordinary Shares, representing approximately 38.3% of the issued share capital of
the Company.



Mike Kerins, Chief Executive of Cytomyx, commented: "Following a strategic
review by the Board, we believe that the disposal of Cytomyx Ltd is in the best
interests of shareholders. The disposal will strengthen the Company's balance
sheet and allow us to focus on our US biorepository business, which is already
working with many of the world's leading pharmaceutical companies and which has
significant potential for growth."





For further information, please contact:


Cytomyx Holdings plc +44 (0) 1223 508191
Mike Kerins, Chief Executive

Corporate Synergy plc +44 (0) 20 7448 4400
William Vandyk

Buchanan Communications +44 (0) 20 7466 5000
Mark Court/Mary-Jane Johnson








This information is provided by RNS
The company news service from the London Stock Exchange
END

DISIIFFDVAISLIR
Posted at 13/12/2005 22:24 by joyridder
High time this share springs back to life....
Posted at 06/12/2005 23:51 by phacops
Thanks RB but I hate to be right with doomed stocks. I prefer finding ones that could prosper due to good management such as Protherics. If the CEO of Cytomyx went on Dragon's Den he would be laughed out of the studio. I think that cyx will take receivership and certain directors will then take anything left private for a pittance. btw the Langbar debacle will and should make anyone leave AIM stocks such as Cytomyx well alone for a punt these days. The demise of Langbar made a splash but no-one will even hear the plip as Cytomyx gently drowns like a puppy in a grubby sack in the canal.
Posted at 01/11/2005 10:50 by phacops
Another director leaves the ship! Is it sinking? The main problem I feel is that they have put all their hopes on the ion screening service, a problem in 3 ways:

1. Competition, and lots of it.

2. Big Pharma want to keep this type of screening in-house if possible.

3. Nearly all clients would need the screening to be performed in FDA-approved labs, wouldn't they? CYX labs are NOT FDA APPROVED are they? Getting approval is expensive and takes ages.

Why would a drug company bother with Cytomyx when the FDA would not even consider their screening results when looking to approve a drug? It has been over a year now since the service was launched and no real customers have been announced. Do they even hold the patents or licence agreements for any of their ion channels (except the Wyeth one)?!!

Personally I think it'll all be over by Christmas.
Posted at 19/1/2005 10:53 by raldo
Cytomyx Holdings PLC
19 January 2005


For immediate release 19 January 2005

CYTOMYX HOLDINGS PLC

('Cytomyx' or 'the Company')

Preliminary results for the year ended 30 September 2004


Cytomyx Holdings plc (AIM: CYX), the leading provider of drug discovery products
and services, is pleased to announce its full year results for the year ended 30
September 2004.

Highlights:

• Turnover up 11 per cent at £5.66 million (2003: £5.10 million)
• Gross profit up 32 per cent at £3.38 million (2003: £2.56 million)
• Gross profit margin 60 per cent (2003: 50 per cent)
• Net loss £915,661 (2003: net loss £414,051), reflecting investment in new
US operations
• Successful institutional Placing to raise £1.9 million completed January
2004
• Acquisition of Clinomics Biosciences Inc., a US company with a major
collection of highly characterised human tissue samples, in January 2004
• Clinomics' new Oncology Cell Signalling Database licensed to AstraZeneca
in March 2004
• Significant expansion in the number of ion channel cell lines from 2 to 17
• Collaboration with Moffit Cancer Center, Florida, in July 2004



Highlights post the year end:

• Molecular Probes distribution contract reinstated
• Clinomics' integration with Cytomyx Ltd and equity fund raising facility
approved in December 2004
• $2.5 million convertible loan facility arranged through Laurus Master Fund
in December 2004



Commenting on the results, Mike Kerins, Cytomyx' Chief Executive, said: 'We are
delighted with the progress made during the year, reflected in the fact that we
now work regularly for eight out of the top ten pharmaceutical companies
worldwide. The developments post the year end, including additional flexibility
in financing the company, together with current trading give us confidence in
the year ahead.'



For further information, please contact:

Cytomyx Holdings plc 01223 508191
Mike Kerins, Chief Executive

Buchanan Communications 020 7466 5000
Mark Court/Mary-Jane Johnson

The Wall Street Group +1 212 888 4848
Ron Stabiner





CYTOMYX HOLDINGS PLC

Preliminary Statement for the year ended 30 September 2004

CHAIRMAN'S STATEMENT

Cytomyx has had an exciting year of growth and consolidation. This has included
not only a strengthening of gross profit margins through new high value
contracts in the second half of the financial year, but also the acquisition in
January 2004 of US-based Clinomics Biosciences Inc ('Clinomics'), a company
whose unique capabilities give us the potential for substantial growth in future
years.

As a result of this acquisition, we have been pleased to welcome Stephen Turner,
the Founder and CEO of Clinomics, to our Board. Mr Turner has a distinguished
track record in the life science industry and will be a major contributor to the
future direction of the group.

The acquisition of Clinomics will facilitate a number of plans that we have to
strengthen our offering of drug discovery technology solutions on a global
basis.

During the year, Cytomyx Ltd has greatly accelerated its progress in the
development of high value products used in drug discovery. A major effort to
develop recombinant cell lines that express ion channel proteins has been highly
successful and we are now recognised as the world's leading developer of these
systems. These high value products are used to develop new treatments in areas
such as pain, epilepsy and heart disease, as well as being widely used to test
new drugs for their potential to cause serious cardiac toxicity side effects.
These products have shown considerable promise for future revenues.

Clinomics has established a very large collection of human tissue samples,
spanning most of the major diseases currently being investigated by the
pharmaceutical industry. All of the samples in the collection are linked to
detailed clinical information from the donor patient and these are used by our
clients to discover new genes involved in disease progression.

Since January, we have relocated Clinomics to a new facility in Albany, New
York, and made rapid strides in expanding its offering of products to the
pharmaceutical industry. During the year we were successful in securing a number
of major contracts with leading pharmaceutical companies, including AstraZeneca.
In addition, we entered into a major new initiative to develop new Cancer Tissue
MicroArrays (our core technology) with the prestigious Moffitt Cancer Centre in
Florida.

We believe that there are many significant synergies between the Clinomics and
Cytomyx Ltd businesses and, in order to best exploit these, it is our intention
to merge the two companies into a single global business unit early in 2005.
While the integration of Clinomics is not yet complete, early indications are
that this will be a powerful and accretive acquisition of the Cytomyx group.

Cambridge BioScience Ltd continued to perform well, and, after extensive
negotiation, we were delighted to announce re-attaining the distribution
contract for Molecular Probes following its sale to Invitrogen Corporation.
Cambridge BioScience Ltd during the year has also initiated a number of exciting
new distribution contracts with innovative US suppliers.

Fund raising

Interest in the group's key strategic products and services has been strong
during the year. We also recognise the need to strengthen our position in the
critical US marketplace, which accounts for around 50% of global pharmaceutical
R&D expenditure. The acquisition of Clinomics was our first major step towards
strengthening our activities in the US.

As a result of this acquisition, we have received interest from several US-based
investors and in December we agreed to an offer of a $2.5m convertible loan
facility from Laurus Funds that will expand available working capital necessary
for our increased level of activity in the US. We anticipate continued growth
through the group in light of our new US activities.

Financial

The group grew its revenues by more than 11% to £5,664,252 in 2004 from
£5,101,315 in 2003. This growth came from new and acquired activities, some of
the growth being temporarily masked by the temporary loss of the Molecular
Probes contract and the decision to wind down some low margin activities such as
DNA sequencing services. Gross profit has grown to £3,383,859 from £2,560,138 in
2003. Notwithstanding the net loss in the first half which, to a large extent,
reflected costs related to the investment in and relocation of Clinomics, our
second half provided firm evidence of increasing gross profit margins including
the positive impact of the Clinomics' acquisition.



Dividend

In light of the loss for the year, the early stage nature of the company and the
ongoing need for investment to grow the Cytomyx Group, the Board does not
recommend the payment of a dividend for the year.

Summary

The group has continued to focus on developing world class technologies for use
in pharmaceutical R&D and we are now seeing strong demand for these key
products. The strategically important acquisition of Clinomics puts us in a
leading position in a major growth market and provides access to the critical US
market. We have also seen strong interest from the US investment community who
have taken notice of our increasing focus on business opportunities in North
America.

We believe 2005 will be a year of significant consolidation, growth and
development of our increasingly successful pharmaceutical solutions business.





Dr. Bill Mason

Chairman

19 January 2005





CONSOLIDATED PROFIT AND LOSS ACCOUNT

Year ended 30 September 2004
Note 2004 2003
£ £

TURNOVER
Existing operations 4,993,523 5,101,315
Acquisitions 670,729 -

Turnover - continuing operations 5,664,252 5,101,315

Cost of sales (2,280,393) (2,541,177)

Gross profit 3,383,859 2,560,138

Distribution costs (137,300) (152,937)
Administrative expenses (4,218,815) (2,757,265)
Other operating income - 15,969


OPERATING LOSS
Existing operations (814,880) (334,095)
Acquisitions (157,376) -

Operating loss - continuing operations (972,256) (334,095)
Restructuring costs - (118,086)

LOSS ON ORDINARY ACTIVITIES BEFORE INTEREST (972,256) (452,181)

Interest receivable and similar income 22,124 7,592
Interest payable and similar charges (46,960) (32,328)

LOSS ON ORDINARY ACTIVITIES BEFORE TAXATION (997,092) (476,917)
Tax on loss on ordinary activities 81,431 62,866

LOSS FOR THE FINANCIAL YEAR (915,661) (414,051)


Loss per ordinary share (pence) 2 (2.42) (1.59)

Diluted loss per ordinary share (pence) 2 (2.42) (1.59)






CONSOLIDATED BALANCE SHEET

30 September 2004
Note 2004 2003
£ £

FIXED ASSETS
Intangible assets 4,479,363 1,233,895
Tangible assets 1,615,138 1,069,576

6,094,501 2,303,471


CURRENT ASSETS
Stocks 477,815 375,799
Debtors
Due after more than one year 60,600 60,600
Due within one year 964,402 1,184,044
Short term investments 450,000 -
Cash at bank and in hand 387,553 414,529

2,340,370 2,034,972
CREDITORS: amounts falling due
within one year (1,330,278) (869,695)

NET CURRENT ASSETS 1,010,092 1,165,277

TOTAL ASSETS LESS CURRENT LIABILITIES 7,104,593 3,468,748

CREDITORS: amounts falling due
after more than one year (880,194) (1,158,327)

6,224,399 2,310,421


CAPITAL AND RESERVES 3
Called up share capital 1,044,809 701,230
Share premium account 5,107,518 3,478,203
Share capital to be issued 675,817 -
Merger reserve 2,089,460 (99,900)
Foreign exchange reserve (8,432) -
Profit and loss account (2,684,773) (1,769,112)

EQUITY SHAREHOLDERS' FUNDS 6,224,399 2,310,421




COMPANY BALANCE SHEET

30 September 2004
Note 2004 2003
£ £

FIXED ASSETS
Tangible assets 2,495 -
Investments 3,394,016 102,000

3,396,511 102,000


CURRENT ASSETS
Debtors
Due after more than one year 4,654,580 3,856,571
Due within one year 22,364 27,287
Short term investments 450,000 -
Cash at bank and in hand 74,967 6,180

5,201,911 3,890,038

CREDITORS: amounts falling due within one year (221,309) (42,500)

NET CURRENT ASSETS 4,980,602 3,847,538

TOTAL ASSETS LESS CURRENT LIABILITIES 8,377,113 3,949,538


CAPITAL AND RESERVES 3
Called up share capital 1,044,809 701,230
Share premium account 5,107,518 3,478,203
Share capital to be issued 675,817 -
Merger reserve 2,189,360 -
Profit and loss account (640,391) (229,895)

EQUITY SHAREHOLDERS' FUNDS 8,377,113 3,949,538




CONSOLIDATED CASH FLOW STATEMENT

Year ended 30 September 2004
Note 2004 2003
£ £

Net cash outflow from operating activities 4 (122,629) (920,219)

Returns on investments and servicing of finance 5 (24,836) (24,736)

Taxation 5 58,338 10,880

Capital expenditure and financial investment 5 (617,755) (74,002)

Acquisitions 5 (243,003) (369,982)

Net cash outflow before management of liquid resources and
financing (949,885) (1,378,059)

Management of liquid resources 5 (450,000) -

Financing 5 1,372,909 1,868,502

(Decrease) increase in cash in the year 6 (26,976) 490,443




RECONCILIATION OF NET CASH FLOW TO MOVEMENT IN NET DEBT

2004 2003
£ £

(Decrease) increase in cash in the year (26,976) 490,443
Cash outflow from decrease in lease financing 44,142 24,320
Cash outflow from decrease in loan notes 365,464 25,000
Cash inflow from new bank loan - (100,000)
Cash outflow from increase in liquid resources 450,000 -

Change in net debt resulting from cash flows 832,630 439,763
Loans and finance leases acquired with subsidiary (48,789) -
New finance leases (34,129) (46,243)
New loan notes - (1,180,000)

Change in net debt 749,712 (786,480)

Net debt at beginning of year (911,827) (125,347)

Net debt at end of year (162,115) (911,827)






STATEMENT OF TOTAL RECOGNISED GAINS AND LOSSES

Year ended 30 September 2004
2004 2003

£ £

Loss for the financial year (915,661) (414,051)
Currency translation difference on foreign currency net
investments (8,432) -

Total gains and losses since last annual report (924,093) (414,051)






NOTES

The information set out above does not constitute the Company's statutory
accounts for the years ended 30 September 2004 or 2003, but is derived from
those accounts, and is prepared on the basis of the accounting policies as
set out in the most recently published set of annual financial statements.
Statutory accounts for 2003 have been delivered to the Registrar of Companies,
and those for 2004 will be delivered following the Company's Annual General
Meeting. The auditors have reported on those accounts; their report was
unqualified and did not contain a statement under section 237(2) or (3) of the
Companies Act 1985.

LOSS PER ORDINARY SHARE

The diluted loss per share takes into account the dilutive effect of share
options. Ordinary shares which are potentially issuable are only included in the
calculation of diluted earnings per share if their issue would decrease net
profit per share or increase net loss per share. The exercise of share options
does not increase the basic loss per share and therefore the basic and diluted
loss per share remain the same.

The calculation of basic loss per ordinary share is based on a loss of £915,661
(2003 - £414,051) and on 37,878,653 (2003 - 26,103,565) ordinary shares being
the weighted average number of ordinary shares in issue during the year.


RECONCILIATION OF MOVEMENTS IN SHAREHOLDERS' FUNDS AND STATEMENT OF MOVEMENTS ON RESERVES

Called up Share Share Foreign Profit and
share premium capital to Merger exchange loss
capital account be issued reserve reserve account Total
£ £ £ £ £ £ £

Group
Balance at 1 October 2003 701,230 3,478,203 - (99,900) - (1,769,112) 2,310,421
Loss for the year - - - - - (915,661) (915,661)
Shares issued 343,579 1,761,800 - 2,189,360 - - 4,294,739
Shares to be issued - - 675,817 - - - 675,817
Currency translation
differences on foreign
currency net investments - - - - (8,432) - (8,432)
Costs set against share
premium - (132,485) - - - - (132,485)

Balance at 30 September
2002 1,044,809 5,107,518 675,817 2,089,460 (8,432) (2,684,773) 6,224,399

Company
Balance at 1 October 2003 701,230 3,478,203 - - - (229,895) 3,949,538
Loss for the year - - - - - (410,496) (410,496)
Shares issued 343,579 1,761,800 - 2,189,360 - - 4,294,739
Shares to be issued - - 675,817 - - - 675,817
Costs set against share
premium - (132,485) - - - - (132,485)

Balance at 30 September
2002 1,044,809 5,107,518 675,817 2,189,360 - (640,391) 8,377,113


Share capital to be issued represents Deferred Contingent Consideration in
relation to the acquisition of Clinomics Biosciences Inc.



NET CASH OUTFLOW FROM OPERATING ACTIVITIES
2004 2003
£ £

Operating loss (972,256) (334,095)
Depreciation charge 260,389 196,350
Loss on disposal of fixed assets 1,150 -
Amortisation of goodwill and intangibles 204,953 63,016
Exceptional restructuring costs - (118,086)
Decrease (increase) in debtors 333,737 (658,770)
Increase in stocks (102,016) (160,803)
Increase in creditors 151,414 92,169

Net cash outflow from operating activities (122,629) (920,219)


ANALYSIS OF CASH FLOWS FOR HEADINGS NETTED IN THE CASH FLOW STATEMENT
2004 2003
£ £
Returns on investments and servicing of finance
Interest received 22,124 7,592
Interest paid (7,227) (32,328)
Interest element of finance lease rental payments (39,733) -

Net cash outflow from returns on investments and servicing of finance (24,836) (24,736)

Taxation
Research and development tax credit 58,338 10,880

Capital expenditure and financial investment
Payments to acquire tangible fixed assets (512,972) (57,073)
Receipts from the sale of fixed assets 6,611 -
Payments to acquire intangible fixed assets (111,394) (16,929)

Net cash outflow from capital expenditure and financial investment (617,755) (74,002)

Acquisitions
Purchase of trade and assets of Cambridge BioScience Limited - (319,982)
Purchase of trade and assets of Cytocell Limited - (50,000)
Purchase of Clinomics Biosciences Inc (236,460) -
Overdraft acquired with subsidiary (6,543) -

(243,003) (369,982)

Management of liquid resources
Increase in short-term investments (450,000) -

Financing
Proceeds from issue of ordinary share capital 1,915,000 2,269,000
Cost of issuing ordinary share capital (132,485) (451,178)
Capital element of finance lease rental repayments (44,142) (24,320)
Repayment of loan notes (365,464) (25,000)
New bank loan - 100,000

Net cash inflow from financing 1,372,909 1,868,502




ANALYSIS OF CHANGES IN NET DEBT

Acquisition
At 1 excluding Other At 30
October Cash cash and non-cash September
2003 flows overdraft changes 2004

£ £ £ £ £

Cash at bank and in hand 414,529 (26,976) - - 387,553

Debt due after one year (1,145,000) 224,103 (17,428) 83,025 (855,300)
Debt due within one year (110,000) 141,361 (31,361) (83,025) (83,025)
Finance leases (71,356) 44,142 - (34,129) (61,343)

(1,326,356) 409,606 (48,789) (34,129) (999,668)

Short term investment - 450,000 - - 450,000

Net debt (911,827) 832,630 (48,789) (34,129) (162,115)



This information is provided by RNS
The company news service from the London Stock Exchange
Cytomyx share price data is direct from the London Stock Exchange

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