Provexis Share Discussion Threads

[lafin] 29/11/2016 10:03

Or you would rather not say?
Apologies if a silly question.

[lafin] 29/11/2016 10:02

Very sensible of you.
Have you any idea what caused this rise in volume and SP,or don't you really care ?

[senor_sensible] 29/11/2016 09:18

lol, greedy short termers usually turn into long termers, not out of choice but because they get locked in :-)

I have been buying and selling PXS since 2006 s you could say I have a long term interest but the key is I always sell and bank profits.

Good luck anyone holding on, maybe we will get a dead cat bounce of 0.4p

[underhill2] 29/11/2016 09:06

If you are in for the long term you have made no mistake. If you are in for the short term - yes you have made a mistake !I'm in here for the long term

[senor_sensible] 29/11/2016 08:58

Not intending to gloat but looks like my mistake was not selling the other 25% :-(

[librag] 28/11/2016 11:32

Thanks for the spelling check. It's gratifying that you've read my post carefully.

Perhaps I was daydreaming of a margarine tub half full of toms. I like the shot seabird better, so I'll give you that. :)

Good advice though. These boards do spike my BP. Allergic to silly persons I guess.
GL.

[gunsofmarscapone] 28/11/2016 11:31

And for goodness sake calm down, very unhealthy approach to life.

[gunsofmarscapone] 28/11/2016 11:24

Ah quite right, I did use the word 'could' though thus creating a conditional statement.

Whats a haemorrhagic stork anyway? A tumescent genital organ weeping haemoglobin? A freshly shot seabird? Good grief man!

[librag] 28/11/2016 10:47

Guns;
#1. "Fruitflow (tm) has NO negative effect on normal clotting pathways"
#2. "... we can infer (subject to research) that Fruitflow, in reducing clot formation ..."

#2 first: There is no proof that FF reduces clot formation. We haven't done the in-vivo studies, just lab based. It's good for a start but not definite.
#1: We actually don't even know if FF has an effect or not on normal clotting pathways. IIRC higher dose WSTC might have an effect, certainly the trials to date have limited the dose studied. Equally we have no evidence at all for the effect in-vivo.

For clarity, I've sold 40% (I previously guessed at 30% when talking with SS) of my holdings. We could easily go up to 2p but just as easily drop back.

" ... with zero increased risk of haemorrhagic storke.tbc." I accept it needs to be confirmed but until then you can't say ZERO RISK. FFS.

You, and others are getting carried away.

[gunsofmarscapone] 28/11/2016 10:13

The aim is to improve heart health and thus increase longevity, that was the aim of Prof Duttaroy in investigating the reasons for increased healthy lifespan in the med.

This is a critical point; a long HEALTHY life, not just a long life. Heart disease is often very disabling and leads to a plethora of associated disease states. Obesity due inability to exercise, loss of neurological function due to poor oxygenation of tissue, pain, pulmonary edema. Social dysfunction occurs as many cardiac patients are unable to care for others and indeed are often dependent on carers. The economic costs are huge for societies.

Stroke, now there is an interesting avenue for research. FRUITFLOW(tm) has NO negative effect on normal clotting pathways, moreover as most embolic strokes are often caused by micro embolii originating from other regions in the vascular tree where clots already exist!

Therefore we can infer (subject to research) that Fruitflow, in reducing clot formation in the body could very well have a dramatic effect in reducing embolic stroke with zero increased risk of haemorrhagic stroke.tbc.

[nestoframpers] 28/11/2016 09:37

Thanks Libra , looks like I have been extrapolating , eager to believe my money isn't lost here .Off to work will look in detail later.

[librag] 28/11/2016 09:34

It's even simpler.
"Sticky blood" increases your chances of stroke.
Less platelet aggregation decreases "sticky blood".
FF decreases "sticky blood".

Unfortunately for you, that doesn't mean that FF decreases your chances of stroke.
Yes, the mechanism looks to be there and yes, FF might but it's not shown by the data. The Prof. of course is well aware of that, as is OKennedy. That's why they're careful to say that FF IS NOT a replacement for Aspirin. If you were at the AGM you'd have heard them say that.

Small example (and there are many more), from memory 10% of strokes are haemorrhagic, not embolic. Even if FF reduced the chance of embolic stroke, what effect does it have on haemorrhagic stroke? What if it did reduce embolic stroke but increase haemorragic stroke? What if the mortality figures were actually worse overall? What if the mortality was reduced but the surviving morbidity was worse?

That's why we need clinical trials. You're quoting non-clinical trials and extrapolating. Very dangerous.

So really, it's not simple at all.
GL.

[gunsofmarscapone] 28/11/2016 09:25

Its a fair call often to crystallise gains yet, I think 75% is a little on the risk averse side Sensible! Still I guess the clues in your name.

[nestoframpers] 28/11/2016 09:14

Very simple sticky blood increases your chances of a stroke , more platelet aggregation decreases the chances , so in some cases will prevent a stroke , that is bolted on .

[nestoframpers] 28/11/2016 09:10

I think Professor Asim Duttaroy who I was quoting knows more than you Libra.Is he medically illiterate ?

[librag] 28/11/2016 08:54

SS; ditto, though only 30% sold. We'll see, the P&D merchants are certainly playing.

NoR; I'm so tired of medically illiterate posters spouting nonsense about health effects. Just because you quote a paper, doesn't mean you're right. You've misunderstood what ADR's paper actually says. Takes years of training to get it right.
There is no evidence that FF reduces the risk of stroke, or any other cardiovascular disease. Neither is there any clinical evidence to say that FF can replace Aspirin or indeed reduce BP or improve erections etc. etc.

There is however, strong circumstantial evidence that it MIGHT. I'd love to run a small (ahem) trial on the latter. I'm afraid our scientists don't seem to have the imagination ...

[senor_sensible] 28/11/2016 07:41

Libra, Sold 75% and banked very healthy profits, leaving the rest to run in case the rampers have continued success. Lots of resistance between the 1p to 2p range with lot of long term holders willing to escape IMO, not sure if enough new punters can fill the gap.

Happy to be proved wrong and hedged my bets anyway :-)

[wheelds] 27/11/2016 23:45

Good luck to all fellow investors.

[nestoframpers] 27/11/2016 22:54

Yes we are all hoping , after 7 years of down down down I had given up. Now loss is 27% only after looking at 99% for years

[glenbo1] 27/11/2016 22:28

NestoframpersIf the BP results are positive then this really will receive the press coverage it deserves. All PXS needs is better marketing and if China is the market then it will be huge.This week could be very interesting.

[nestoframpers] 27/11/2016 22:19

Professor Asim Duttaroy of Provexis, who made the breakthrough discovery of the active anti-clotting ingredients in the tomato, said: “We at Provexis are hoping to raise awareness of the three pillars of cardiovascular health: healthy cholesterol, blood pressure levels and, just as important, healthy blood flow.


“Healthy blood flow is fundamental to maintaining a healthy circulation, and avoiding dangerous blood clots, which can lead to heart attack, stroke and pulmonary embolism.

“Within the blood there are platelets, released from bone marrow, which can change function from being smooth to spiky and sticky.

“In a smooth state they circulate easily but if they become spiky they can stick to the blood vessels and send out signals for other platelets to join them to form a clot. While this is obviously vital in an injury, it’s dangerous if it happens inside a blood vessel and any resulting clot interrupts healthy blood flow.

“Many people don’t know that as they get older their blood platelets tend to get spiky and sticky more of the time, meaning their blood flows less smoothly.



“Plus ’activated’ sticky platelets are more likely in people who have high cholesterol or blood pressure, are overweight, smoke, have a poor diet, lack exercise, have diabetes or experience stress.

“Generally, everyone’s blood flow can change hourly based on any of these lifestyle factors, meaning we all need to be more aware of managing it.

“So, we’re delighted that after making the discovery and years of gathering and publishing evidence across many human trials, we’ve credibly proved that Fruitflow works to maintain a healthy blood flow, in a similar way to aspirin, but with a milder and reversible action, making it suitable for use as a dietary antiplatelet.”

[glenbo1] 27/11/2016 22:12

Underhill agreed.People should only post worthy information and cut the crude comments and gutter language out.This is speculative I agree but buying in the last hour does not suddenly happen for no reason. I personally think something is brewing either the results of the BP trials or somebody is buying in ..Maybe an RNS this week.

[nestoframpers] 27/11/2016 22:11

Banshee going by the FF trial it is a better option than Aspirin , so yes it will prevent strokes as Aspirin does , I guess at least as many as Aspirin . Why not ask Ian Ford and post up what he says .

[underhill2] 27/11/2016 21:27

A lot of nonsense posts posts this weekend as expected.As a long term investment speculative investment I'm more than happy to hold. The BP results will be very important and will have a major affect on the share price either positive or negative.

[traidemark] 27/11/2016 21:02

Libra. Whatever! I wouldn't initiate an argument as you do without good cause. And then call a company fraudsters. Dangerous ground that my friend.