||EPS - Basic
||Market Cap (m)
Provexis Share Discussion Threads
Showing 45751 to 45770 of 45775 messages
|What has above got to do with Fruitflow?
Nothing at the moment.|
Scientists Just Found Evidence That Neurons Can Communicate in a Way We Never Anticipated
A new brain mechanism hiding in plain sight.
20 FEB 2017
Researchers have discovered a brand new mechanism that controls the way nerve cells in our brain communicate with each other to regulate learning and long-term memory.
The fact that a new brain mechanism has been hiding in plain sight is a reminder of how much we have yet to learn about how the human brain works, and what goes wrong in neurodegenerative disorders such as Alzheimer's and epilepsy.
"These discoveries represent a significant advance and will have far-reaching implications for the understanding of memory, cognition, developmental plasticity, and neuronal network formation and stabilisation," said lead researcher Jeremy Henley from the University of Bristol in the UK.
"We believe that this is a groundbreaking study that opens new lines of inquiry which will increase understanding of the molecular details of synaptic function in health and disease."
The human brain contains around 100 billion nerve cells, and each of those makes about 10,000 connections - known as synapses - with other cells.
That's a whole lot of connections, and each of them is strengthened or weakened depending on different brain mechanisms that scientists have spent decades trying to understand.
Until now, one of the best known mechanisms to increase the strength of information flow across synapses was known as LTP, or long-term potentiation.
LTP intensifies the connection between cells to make information transfer more efficient, and it plays a role in a wide range of neurodegenerative conditions - too much LTP, and you risk disorders such as epilepsy, too little, and it could cause dementia or Alzheimer's disease.
As far as researchers were aware, LTP is usually controlled by the activation of special proteins called NMDA receptors.
But now the UK team has discovered a brand new type of LTP that's regulated in an entirely different way.
After investigating the formation of synapses in the lab, the team showed that this new LTP mechanism is controlled by molecules known as kainate receptors, instead of NMDA receptors.
"These data reveal a new and, to our knowledge, previously unsuspected role for postsynaptic kainate receptors in the induction of functional and structural plasticity in the hippocampus," the researchers write in Nature Neuroscience.
This means we've now uncovered a previously unexplored mechanism that could control learning and memory.
"Untangling the interactions between the signal receptors in the brain not only tells us more about the inner workings of a healthy brain, but also provides a practical insight into what happens when we form new memories," said one of the researchers, Milos Petrovic from the University of Central Lancashire.
"If we can preserve these signals it may help protect against brain diseases."
Not only does this open up a new research pathway that could lead to a better understanding of how our brains work, but if researchers can find a way to target these new pathways, it could lead to more effective treatments for a range of neurodegenerative disorders.
It's still early days, and the discovery will now need to be verified by independent researchers, but it's a promising new field of research.
"This is certainly an extremely exciting discovery and something that could potentially impact the global population," said Petrovic.
The research has been published in Nature Neuroscience.
|make your own ending.|
|Vascular dementia is usually caused by a stroke or series of strokes,as far as I know, so if Fruitflow stops a stroke happening then obviously it would affect memory Mr.Grumpy but ..........................|
|I've no idea and TBH I don't think he/she has either. :)
Have a good w/e Bernie. Off for a spot of DIY.|
The article I mentioned was HTTP://dispatchweekly.com/2017/02/brits-aware-managing-blood-pressure-cholesterol-cardiovascular-health-still-ill-informed-blood-circulation/
I"ve no idea what Wheelie was typing about. He's fairly harmless in the grand scheme of things though.|
|The heart is an engine and as like any engine you have to keep the oil clear of clotting-up or your motor will cease up.
Fruitflow helps keep our engines/hearts from ceasing up by helping to maintain healthy blood flow by breaking down the blood clots; but I can not see how it can help with memory loss on its own as our brains are much more complicated with regard to storage space for our short term memories which then feed into our long term memory storage area. Unless you replace the alcohol with a Fruitflow drink and encourage the patient to say play football or table tennis and have a laugh while the brain has to switch back on to play and be merry and as with table tennis co-ordinate hand-eye-and memory part of the brain to simply bat the ball back and have a laugh in doing so etc.
A simple test without having fun on memory using just a Fruitflow drink I can not see it working but as stated above the brain can be re-stimulated in combinations of eat drink and be merry.IMHO
Bought back in again yesterday, just one million at 0.72p (was only 0.68p when I tested it but) was hoping and waiting for share price to drop even further so I could buy a few more, but all the signs said buy now.
Fruitflow is a great product.|
|However,I agree about memory trial.|
|Last three posts were
A picture of a tomato
and a good article about Fruitflow.|
|Bernie; Fractals are fascinating ... look at the pattern since the 1.3p and compare it to the 15p peak. I guess you're right about the next (if?) fundraise price around the 200EMA.
Putting aside whatever inane comments made in the last 3 posts, and re. the memory trial ... I asked about this at the last AGM. NoK ducked the question IIRC. In my view, the trial was and is, a waste of time.|
|16/02/2017:- Good article on the benefits of our Fruitflow:-
|Just a thought , is the revenue from fruitflow +omega3 shared with DSM ?|
Yea, probably. I'd guess it'll be between 0.5p and 0.55p, which isn't a million miles away from the current mid-price of ~.68p
|Looks like any placing will be around this price|
|what has been seen cannot be unseen even if you type a load of nonsense like some people do|
|LibraG - you have to see the huge loss of potential here in terms of money that was literally haemorraged on SIS (remember the "admin costs" of £2.4m or whatever they were in the first year?).
Now you think of the £8m that SIS cost us (cash and shares) what we could have done with that in terms of clinical trials and marketing budget for our new product!!!
Then the ludicrous director salaries to date - literally million spent on those alone - for doing what exactly???
Yet some holders claim to hold tens of millions???
|What's this then RP? Holding posters to account? Shame on you. :)
You're right about apathy, not one single call back after our pub visit.|
|Sahreholder apathy has been THE single biggest reason why this company has been run into the ground.
Hadn't someone told us they were not going to post here anymore?|
|Maybe even more now,the 76% was from 2016|
|Oh I forgot to mention 76% of shareholders NEVER attend AGMs.|