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IMM Immupharma Plc

2.30
0.06 (2.68%)
Last Updated: 15:35:26
Delayed by 15 minutes
Share Name Share Symbol Market Type Share ISIN Share Description
Immupharma Plc LSE:IMM London Ordinary Share GB0033711010 ORD 1P
  Price Change % Change Share Price Bid Price Offer Price High Price Low Price Open Price Shares Traded Last Trade
  0.06 2.68% 2.30 2.30 2.40 2.30 2.20 2.20 1,199,889 15:35:26
Industry Sector Turnover Profit EPS - Basic PE Ratio Market Cap
Finance Services 0 -3.81M -0.0114 -2.02 7.67M

Immupharma PLC Holding(s) in Company (3933R)

08/03/2016 11:11am

UK Regulatory


TIDMIMM

RNS Number : 3933R

Immupharma PLC

08 March 2016

 
 RNS : FOR IMMEDIATE RELEASE   8 MARCH 2016 
 

TR1 NOTIFICATION OF MAJOR INTEREST BY AVIVA

ImmuPharma PLC (LSE:IMM), ("ImmuPharma" or the "Company"), the specialist drug discovery and development company, confirms that it has received a TR-1 by Aviva plc and its subsidiaries ("Aviva") confirming its increased holding in ImmuPharma to 11,332,848 Ordinary Shares.

This increased holding follows on from Aviva's participation in ImmuPharma's recent GBP8.4 million fundraising in February the issue and allotment of, in aggregate, 33,158,756 new ordinary shares of 10 pence each in the Company. ImmuPharma now has a total of 121,781,219 Ordinary Shares in issue, which takes Aviva's current position in the Company to 9.31%.

Full disclosure of the TR1 is shown below:

 
 TR-1: NOTIFICATION OF MAJOR INTEREST IN SHARES(i) 
-------------------------------------------------- 
 
 
 
 1. Identity of the issuer or                                       Immupharma plc 
  the underlying issuer 
  of existing shares to which 
  voting rights are 
  attached: (ii) 
-----------------------------------------------------------------  ------------------------------------------ 
 2 Reason for the notification (please tick the appropriate 
  box or boxes): 
------------------------------------------------------------------------------------------------------------- 
 An acquisition or disposal of voting rights 
----------------------------------------------------------------------------------------------------------- 
 An acquisition or disposal of qualifying financial 
  instruments which may result in the acquisition 
  of shares already issued to which voting rights 
  are attached 
----------------------------------------------------------------------------------------------------------- 
 An acquisition or disposal of instruments with 
  similar economic effect to qualifying financial 
  instruments 
----------------------------------------------------------------------------------------------------------- 
 An event changing the breakdown of voting rights 
----------------------------------------------------------------------------------------------------------- 
 Other (please 
  specify):                                                    CHANGE TO THE NUMBER OF VOTING RIGHTS 
                                                               IN ISSUE, FOLLOWING THE RECENT ISSUE 
                                                               OF EQUITY. 
-----------------------------------------------------------  ---------------------------------------------- 
 3. Full name of person(s)                                      Aviva plc & its subsidiaries 
  subject to the 
  notification obligation: 
  (iii) 
-------------------------------------------------------------  ---------------------------------------------- 
 4. Full name of shareholder(s)                                 Registered Holder: 
  (if different from 3.):(iv) 
                                                                 BNY Norwich Union Nominees 
                                                                 Limited 628,858* 
 
                                                                 Chase (GA Group) Nominees 
                                                                 Limited 9,103,449* 
 
                                                                 *denotes direct interest 
 
                                                                 Chase (GA Group) Nominees 
                                                                 Limited 696,778 
 
                                                                 Chase Nominees Limited 275,292 
 
                                                                 Vidacos Nominees Limited 528,471 
-------------------------------------------------------------  ---------------------------------------------- 
 5. Date of the transaction                                     04 March 2016 
  and date on 
  which the threshold is 
  crossed or 
  reached: (v) 
-------------------------------------------------------------  ---------------------------------------------- 
 6. Date on which issuer                                        07 March 2016 
  notified: 
-------------------------------------------------------------  ---------------------------------------------- 
 7. Threshold(s) that is/are                                    8% to 7% Change at Direct 
  crossed or                                                     Interest Level (Box 8A) 
  reached: (vi, vii) 
-------------------------------------------------------------  ---------------------------------------------- 
 
 
 
 8. Notified details: 
------------------------------------------------------------------------------------------------------------- 
 A: Voting rights attached to shares (viii, ix) 
------------------------------------------------------------------------------------------------------------- 
 Class/type           Situation previous               Resulting situation after 
  of                   to the triggering                the triggering transaction 
  shares               transaction 
 
  if possible 
  using 
  the ISIN 
  CODE 
-------------------  -------------------------------  ------------------------------------------------------- 
                      Number               Number      Number       Number of               % of voting 
                       of                   of          of           voting                  rights (x) 
                       Shares               Voting      shares       rights 
                                            Rights 
-------------------  -------------------  ----------  -----------  ----------------------  ------------------ 
                                                       Direct       Direct      Indirect    Direct   Indirect 
                                                                     (xi)        (xii) 
-------------------  -------------------  ----------  -----------  ----------  ----------  -------  --------- 
 Ordinary 
  Shares 
 
  GB0033711010        8,140,848            8,140,848   11,232,848   9,732,307   1,500,541   7.99%     1.24% 
                     -------------------  ----------  -----------  ----------  ----------  -------  --------- 
 
 
 B: Qualifying Financial Instruments 
------------------------------------------------------------------------------------------------------------- 
 Resulting situation after the triggering transaction 
------------------------------------------------------------------------------------------------------------- 
 Type of financial    Expiration           Exercise/                Number of voting        % of voting 
  instrument           date                 Conversion               rights that             rights 
                       (xiii)               Period (xiv)             may be 
                                                                     acquired if 
                                                                     the 
                                                                     instrument 
                                                                     is 
                                                                     exercised/ 
                                                                     converted. 
-------------------  -------------------  -----------------------  ----------------------  ------------------ 
                                                                    100,000 * 
 RIGHT TO RECALL 
  LOANED SHARES       N/A                  N/A                       * Direct Interest      0.08% 
-------------------  -------------------  -----------------------  ----------------------  ------------------ 
 
 
 
 C: Financial Instruments with similar economic effect 
  to Qualifying Financial Instruments (xv, xvi) 
----------------------------------------------------------------------------------------------- 
 Resulting situation after the triggering transaction 
----------------------------------------------------------------------------------------------- 
 Type of financial   Exercise   Expiration   Exercise/     Number of voting     % of voting 
  instrument          price      date         Conversion    rights instrument   rights (xix, 
                                 (xvii)       period        refers to           xx) 
                                              (xviii) 
------------------  ---------  -----------  ------------  -------------------  ---------------- 
 
 
 
 
 Total (A+B+C) 
------------------------------------------------------ 
 Number of voting rights   Percentage of voting rights 
------------------------  ---------------------------- 
 11,332,848                9.31% 
------------------------  ---------------------------- 
 
 
 9. Chain of controlled undertakings through which the 
  voting rights and/or the 
  financial instruments are effectively held, if applicable: 
  (xxi) 
--------------------------------------------------------------------------------- 
                            The voting rights are managed and controlled by Aviva 
                            Investors Global Services Limited, with the following 
                                               chain of controlled undertakings:- 
 
                                         Aviva Investors Global Services Limited: 
                                                  *    Aviva plc (Parent Company) 
 
 
                       *    Aviva Group Holdings Limited (wholly owned subsidiary 
                                                                    of Aviva plc) 
 
 
                              *    Aviva Investors Holdings Limited (wholly owned 
                                      subsidiary of Aviva Group Holdings Limited) 
 
 
                       *    Aviva Investors Global Services Limited (wholly owned 
                                  subsidiary of Aviva Investors Holdings Limited) 
 
 Proxy Voting: 

March 08, 2016 06:11 ET (11:11 GMT)

--------------------------------------------------------------------------------- 
 10. Name of the proxy holder:                  See Section 4 
---------------------------------------------  ---------------------------------- 
 11. Number of voting rights proxy 
  holder will cease 
  to hold: 
---------------------------------------------  ---------------------------------- 
 12. Date on which proxy holder will 
  cease to hold 
  voting rights: 
---------------------------------------------  ---------------------------------- 
 
 
  13. Additional information:                    Figures are based the revised 
                                                 total number of voting rights 
                                                 of 121,781,219 as per the 
                                                 recent Confirmation of EIS 
                                                 and VCT Qualifying Status 
                                                 and Issue of Equity announcement 
                                                 of 01 March 2016. 
---------------------------------------------  ---------------------------------- 
 14. Contact name:                                  Michael Dunhill, Aviva plc 
---------------------------------------------  ---------------------------------- 
 15. Contact telephone number:                      01603 685988 
---------------------------------------------  ---------------------------------- 
 
 

-Ends-

 
 For further information please 
  contact: 
                                               + 44 (0) 20 
   ImmuPharma plc (www.immupharma.org)           7152 4080 
   Tim McCarthy, Chairman 
   Lisa Baderoon, Head of Investor 
    Relations                                + 44 (0) 7721 
    Twitter: @immupharma                      413496 
 
    Panmure, Gordon & Co., NOMAD &            +44 (0) 20 7886 
    Broker                                         2500 
   Fred Walsh, Duncan Monteith, Corporate 
    Finance 
    Charles Leigh-Pemberton, Corporate 
    Broking 
 

Notes to Editors

ImmuPharma PLC

ImmuPharma is a pharmaceutical development company listed since 2006 on AIM of the London Stock Exchange (LSE:IMM), focusing on developing novel medicines with high sales potential in specialist markets with serious unmet need. ImmuPharma is led by a commercially focused Board and management team with extensive experience.

ImmuPharma announced on 1 March 2016 the successful completion of a GBP8.4 million fund raise, comprising a Placing and Subscription together with confirmation of EIS and VCT qualifying status. Monies raised will principally be used to complete the pivotal Phase III trial of Lupuzor(TM). Following the issue of the New Ordinary Shares referred to above, ImmuPharma will have 121,781,219 ordinary shares of 10 pence each (the "Ordinary Shares") in issue.

Lupuzor(TM)

Lupuzor(TM) (also referred to as forigerimod, rigerimod, IPP-201101 or P140 is ImmuPharma's lead compound and a potential treatment for lupus (or Systemic Lupus Erythematosus), a chronic, potentially life-threatening auto-immune disease. Lupuzor(TM) has a novel mechanism of action aimed at modulating the body's immune system so that it does not attack healthy cells, and avoids causing adverse side effects. It has the potential to halt the progression of the disease in a substantial proportion of patients.

Lupuzor(TM) has been granted Fast Track status by the US FDA and approval to start Phase III under Special Protocol Assessment (SPA). This SPA was subsequently amended due to its strong safety and efficacy profile to allow for a reduced number of patients in the pivotal Phase III trial thereby reducing the projected cost and time of development considerably.

The pivotal Phase III clinical study is entitled "A 52-Week, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Study to Evaluate the Efficacy and Safety of a 200-mcg Dose of IPP-201101 Plus Standard of Care in Patients With Systemic Lupus Erythematosus". It is a pivotal study designed to demonstrate the safety and efficacy of IPP-201101 and as a last step prior to the filing of the drug for approval with the US Food & Drug Administration ("FDA") and the European Medicines Agency ("EMA"). For more information please visit: www.ClinicalTrials.gov/lupuzor

Commercial Opportunity

There are an estimated five million people globally suffering from Lupus, with approximately 1.5 million patients in the US, Europe and Japan (Source: Lupus Foundation of America). Current 'standard of care' treatments, including steroids and immunosuppressants, can potentially have either serious side effects for patients or limited effectiveness, with over 60% of patients not adequately treated. GSK's Benlysta is the first Lupus drug approved in over 50 years and paves the path to market for Lupuzor(TM). Based on conservative estimates, and taking into account that Benlysta is priced currently at approximately $35,000 per patient per year, Lupuzor(TM) would be entering a market with the potential for multi-billion dollar sales. For more information on Lupuzor(TM) please visit: www.lupuzor.com

This information is provided by RNS

The company news service from the London Stock Exchange

END

HOLFVLFBQXFBBBD

(END) Dow Jones Newswires

March 08, 2016 06:11 ET (11:11 GMT)

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